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Search Results for " dna-dependent protein kinase catalytic subunit "
Targets Recommended: Others

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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T61633 DNA-PK-IN-2

Others Others
DNA-PK-IN-2 is a highly effective inhibitor of DNA-dependent protein kinase (DNA-PK), which is a complex enzyme composed of Ku70/Ku80 heterodimer and DNA-PK catalytic subunit (DNA-PKcs). With its potential applications in cancer research, DNA-PK-IN-2 demonstrates promise as a valuable tool for studying cancer diseases [1].

化合物

DNA-PK-IN-2
Cat.No: T61633
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00476 DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc)

DNA-PKcs,DNA-PK catalytic sub...

Dictyostelium discoideum E. coli
DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) is expressed in E. coli.
TMPH-02314 XRCC5 Protein, Human, Recombinant (His & MBP)

Nuclear factor IV,Lupus Ku autoantigen protein p86,...

Human Baculovirus Insect Cells
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPH-02315 XRCC5 Protein, Human, Recombinant (His & Myc)

ATP-dependent DNA helicase 2 subunit

Human E. coli
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPY-04542 CDK2 Protein, Human, Recombinant (His)

CDKN2,cyclin-dependent kinase 2,p33(CDK2)

Human Baculovirus Insect Cells
CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. Cdks (cyclin-dependent kinases) are heteromeric serine/threonine kinases that control progression through the cell cycle in concert with their regulatory subunits, the c...

重组蛋白

DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc)
Cat.No: TMPH-00476
Species: Dictyostelium discoideum
Expression System: E. coli
XRCC5 Protein, Human, Recombinant (His & MBP)
Cat.No: TMPH-02314
Species: Human
Expression System: Baculovirus Insect Cells
XRCC5 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02315
Species: Human
Expression System: E. coli
CDK2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04542
Species: Human
Expression System: Baculovirus Insect Cells
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