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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T61633 |
DNA-PK-IN-2
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Others | Others |
DNA-PK-IN-2 is a highly effective inhibitor of DNA-dependent protein kinase (DNA-PK), which is a complex enzyme composed of Ku70/Ku80 heterodimer and DNA-PK catalytic subunit (DNA-PKcs). With its potential applications in cancer research, DNA-PK-IN-2 demonstrates promise as a valuable tool for studying cancer diseases [1]. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00476 |
DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc)
DNA-PKcs,DNA-PK cata... |
Dictyostelium discoideum | E. coli |
DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02314 |
XRCC5 Protein, Human, Recombinant (His & MBP)
Nuclear factor IV,Lupus Ku autoantigen protein p86,ATP-depen... |
Human | Baculovirus Insect Cells |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind... | |||
TMPH-02315 |
XRCC5 Protein, Human, Recombinant (His & Myc)
ATP-dependent DNA helicase 2 subunit 2,XRC... |
Human | E. coli |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind... |