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Search Results for " dna polymerase eta "
Targets Recommended: Others

2

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T70337 PNR-7-02

Others Others
PNR-7-02 is an inhibitor of human DNA polymerase eta (Polη).
T72696 UCK2 Inhibitor-3

Others Others
UCK2 Inhibitor-3是一款UCK2 (尿苷胞苷激酶2)的非竞争性抑制剂,其IC50值为16.6 μM。该化合物能在一定程度上补偿因感染或快速分裂的细胞中DHODH (二氢旋酸脱氢酶)功能的缺失,有效地挽救尿苷。此外,UCK2 Inhibitor-3还能抑制DNA聚合酶η和κ,其IC50值分别为56 μM和16 μM。

化合物

PNR-7-02
Cat.No: T70337
Synonym:
Target: Others
UCK2 Inhibitor-3
Cat.No: T72696
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-01237 POLQ Protein, Human, Recombinant (E. coli, His)

DNA polymerase eta,POLQ,DNA

Human E. coli
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul...
TMPH-01238 POLQ Protein, Human, Recombinant (His)

DNA polymerase eta,POLQ,DNA

Human Baculovirus Insect Cells
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul...

重组蛋白

POLQ Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01237
Species: Human
Expression System: E. coli
POLQ Protein, Human, Recombinant (His)
Cat.No: TMPH-01238
Species: Human
Expression System: Baculovirus Insect Cells
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