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Search Results for " dcl "

Targets Recommended: Others

5

抑制剂 & 化合物

1

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T72591	Sp-5,6-DCl-cBIMPS	Others	Others
	Sp-5,6-DCl-cBIMPS 为一种高效特异的 cAMP 依赖性蛋白激酶(cAMP-PK)激活剂，能够促进胰岛素释放，并抑制U46619引起的血小板Rho、Gq及G12/G13的激活[3]。
T27133	DCLX069 DCLX 069,DCLX-069	Histone Methyltransferase	Chromatin/Epigenetic
	DCLX069 是一种选择性蛋白精氨酸甲基转移酶 1 抑制剂，IC50值为 17.9 µM，对 PRMT4 和 PRMT6 的活性较低。它可有效阻断乳腺癌、肝癌和急性髓性白血病细胞系中的细胞增殖。
T8418	DCLK1-IN-1	Others	Others
	DCLK1-IN-1 是选择性的、体内相容的双皮质素样激酶1DCLK1激酶结构域化学探针。它抑制 DCLK1 和 DCLK2 激酶。它具有低毒性，可以研究 DCLK1 的生物学特性，确定其在肿瘤中的作用，如 DCLK1+胰腺导管腺癌。
T79421	DCLK1-IN-2	Others	Others
	DCLK1-IN-2（化合物I-5）为高效DCLK1抑制剂，IC50值为171.3 nM。对SW1990细胞系具有明显的抗增殖活性（IC50为0.6 μM），并展现出体内的抗肿瘤效能。
T9280	CS-0047390 (S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate	Others	Others
	CS-0047390又称tert-Butyl-DCL，PSMA抑制剂，是一种放射显影多肽试剂。

化合物

Sp-5,6-DCl-cBIMPS

Cat.No: T72591

Target: Others

Cat.No: T27133

Synonym: DCLX 069,DCLX-069

Target: Histone Methyltransferase

Cat.No: T8418

Target: Others

Cat.No: T79421

Target: Others

Cat.No: T9280

Synonym: (S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5086	Pharmatose DCL 14 D-乳糖一水合物,D-Lactose monohydrate	Others; Endogenous Metabolite	Metabolism; Others
	Pharmatose DCL 14 (D-Lactose monohydrate) 是内源性代谢产物的一种。

天然产物

Pharmatose DCL 14

Cat.No: T5086

Synonym: D-乳糖一水合物,D-Lactose monohydrate

Target: Others, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03740	DCL Protein, Bacillus subtilis, Recombinant (His) DCL,D-alanine--poly(phosphoribitol) ligase subunit ...	Bacillus subtilis	E. coli
	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the...
TMPY-04752	DCLK1 Protein, Human, Recombinant doublecortin-like kinase 1,CL1,DCLK,CLICK1,DCAMKL1,...	Human	Baculovirus Insect Cells
	DCLK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 78.5 kDa and the accession number is O15075-1.
TMPY-04404	DCLK1 Protein, Human, Recombinant (aa 1-705, His & GST) doublecortin-like kinase 1,CL1,DCDC3A,DCLK,CLICK1,D...	Human	Baculovirus Insect Cells
	DCLK1 Protein, Human, Recombinant (aa 1-705, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 106 kDa and the accession number is O15075-1.

重组蛋白

DCL Protein, Bacillus subtilis, Recombinant (His)

Cat.No: TMPH-03740

Species: Bacillus subtilis

Expression System: E. coli

DCLK1 Protein, Human, Recombinant

Cat.No: TMPY-04752

Species: Human

Expression System: Baculovirus Insect Cells

DCLK1 Protein, Human, Recombinant (aa 1-705, His & GST)

Cat.No: TMPY-04404

Species: Human

Expression System: Baculovirus Insect Cells

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