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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22711 |
DCB
3,3'-dichlorobenzaldazine |
Others; GluR | Neuroscience; Others |
DCB (3,3'-dichlorobenzaldazine) 是 mGluR5 的变构配体,显示出 3,3'-二甲氧基苯扎嗪 (DMeOB) 的负调节作用。 DCB 在 3,3'-二氟苯扎嗪 (DFB) 的帮助下阻断 mGluR 的正变构调节。 | |||
T13378 |
Z-Asp-CH2-DCB
|
Others | Others |
Z-Asp-CH2-DCB 是广谱半胱天冬酶的不可逆抑制剂。 | |||
T27128 |
DCB-3503
NSC716802,NSC 716802,NSC-716802,DCB3503,DCB 3503 |
Others | Others |
Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA. | |||
T34970 |
Tylophorine, (-)-
DCB-3500 |
Others | Others |
Tylophorine, (-)- is a biomedical. | |||
T68320 |
L594881 HCl
|
Others | Others |
L594881, also known as 3',4'-Dichlorobenzamil or DCB, is an inhibitor of Na+/Ca2+ exchanger, Na+ transport and sarcoplasmic reticulum Ca2+ release channels. L594881 can inhibit Na+/Ca2+ exchanger, Na+ transport and sarcoplasmic reticulum Ca2+ release channels. | |||
T8547 |
DCBA
|
Drug Metabolite | Metabolism |
DCBA 是驱虫剂 N-N-diethyl-meta-toluamide (DEET) 的代谢物。尿液中 DCBA 的浓度是评估 DEET 暴露程度的指标。 | |||
T9370 |
dCBP-1
|
Epigenetic Reader Domain; PROTACs | Chromatin/Epigenetic; PROTAC |
dCBP-1 是基于Cereblon 配体的p300/CBP 的选择性双功能降解剂。dCBP-1可以有效的杀死多发性骨髓瘤细胞,并降低驱动 MYC 表达的致癌增强子活性。 | |||
T33226 |
m-Chloro-DCBA
|
Others | Others |
m-Chloro-DCBA is a bioactive chemical. | |||
T81250 |
Ru(bpy)2(dcbpy)NHS dihexafluorophosphate
|
||
Ru(bpy)2(dcbpy)NHS (dihexafluorophosphate)与金纳米颗粒结合, 可构建用于电化学发光检测溶菌酶的扩增系统。 | |||
T33373 |
m-Fluoro-DCBA
|
Others | Others |
m-Fluoro-DCBA is a bioactive chemical | |||
T31223 |
DCBCI0901
DCBCI-0901,DCBCI 0901 |
Others | Others |
DCBCI0901 is an inhibitor of phosphatidylinositide 3-kinase (PI3K), raptor-mTOR (mTOR complex 1 or mTORC1) and rictor-mTOR (mTOR complex 2 or mTORC2) with potential antineoplastic activity. | |||
T37880 |
OPC-167832
|
Others | Others |
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03400 |
DCBLD1 Protein, Human, Recombinant (His)
dJ94G16.1,discoidin, CUB and LCCL domain containing 1,RP1-94... |
Human | HEK293 Cells |
Discoidin, also known as DCBLD1, contains 1 CUB domain, 1 F5/8 type C domain and 1 LCCL domain. It is a 715 amino acid single-pass membrane protein. Discoidin has a discoidin I-like domain which shares a common C-terminal region of about 110 amino acids with the FA58C domain, but whose N-terminal 40 amino acids are much less conserved. Discoidin gene contains 31 distinct gt-ag introns. Transcription produces 18 different mRNAs, 16 alternatively spliced variants and 2 unspliced forms. Discoidin i... | |||
TMPY-03853 |
DCBLD2 Protein, Human, Recombinant (His)
CLCP1,discoidin, CUB and LCCL domain containing 2,ESDN |
Human | HEK293 Cells |
DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor med... |