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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T83885 |
DXR Inhibitor 11a sodium
1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a |
Others | Others |
DXR抑制剂11a是P. falciparum 1-去氧-D-木糖-5-磷酸还原异构酶(DXR; IC50 = 0.11 µM)的抑制剂。它抑制在分离的人类红细胞中P. falciparum的生长(IC50 = 0.37 µM)。 | |||
T83908 |
DXR Inhibitor 11a (free acid)
1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a |
Others | Others |
DXR inhibitor 11a是一种针对P. falciparum 1-脱氧-D-木糖-5-磷酸还原异构酶(DXR; IC50 = 0.11 µM)的抑制剂。它能够抑制在分离的人类红细胞中P. falciparum的生长(IC50 = 0.37 µM)。 | |||
T37988 |
D-Ribulose-5-phosphate (sodium salt)
Ru5P,D-Ribulose-5-phosphate (sodium salt) |
Others | Others |
D-Ribulose-5-phosphate is an intermediate in the pentose phosphate pathway. [1][2] It can be derived from 6-phosphogluconate by a dehydrogenase or from xylulose 5-phosphate by ribulose phosphate 3-epimerase. D-Ribulose-5-phosphate is also an intermediate in carbon fixation in photosynthetic organisms as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics.[3] | |||
T78936 |
Antimalarial agent 27
|
Parasite | Microbiology/Virology |
Antimalarial agent 27 (compound 11a) 是一款针对恶性疟原虫有效的抗疟疾化合物,展现出优异的抑制能力(IC50=0.37 μM)。其机制主要通过抑制目标疟原虫中的DXR (1-脱氧-D-木糖-5-磷酸还原酶),以达成较高抑制效果(IC50=0.11 μM)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TQ0190 |
D-Xylulose
|
Others; Endogenous Metabolite | Metabolism; Others |
D-xylulose 通过葡萄糖醛酸途径中的酶 NAD+ 连接的木糖醇脱氢酶从木糖醇转化,葡萄糖醛酸途径是哺乳动物中重要的木糖醇处理代谢途径。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00557 |
DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc)
1-deoxy-D-xylulose 5-phosphate re... |
E. coli | E. coli |
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). | |||
TMPH-03182 |
DTE Protein, Pseudomonas cichorii, Recombinant (His & Myc)
Ketose 3-epimerase,D-ribulose 3-epimerase,D |
Pseudomonas cichorii | E. coli |
Catalyzes the epimerization of various ketoses at the C(3) position. It is able to interconvert D-tagatose and D-ribulose to D-sorbose and D-xylulose, respectively. The enzyme is also able to accept other ketopentoses such as D-psicose with lower efficiency. DTE Protein, Pseudomonas cichorii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.1 kDa and the accession number is O50580. |