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Search Results for " cytomegalovirus "

Targets Recommended: Others HSV

46

抑制剂 & 化合物

4

天然产物

1

化合物库

16

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L1800	抗感染化合物库		2938 compounds
	2938 种具有抗感染活性的化合物的特有集合，包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性；

化合物库

抗感染化合物库

Cat.No: L1800

Compounds: 2938

Cat. No.	Product Name	Target	Signaling Pathways
T0718	Brivudine Bromovinyldeoxyuridine,BVDU,溴夫定	Others; HSV	Microbiology/Virology; Others
	Brivudine (BVDU) 是胸苷类似物，有抗病毒活性，用于早期急性带状疱疹的研究。
T38514	PMEDAP	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	PMEDAP 是有效的人类免疫缺陷病毒 (HIV) 复制抑制剂。它具有抗小鼠巨细胞病毒活性。它有效抑制莫罗尼鼠肉瘤病毒诱导的肿瘤形成和相关死亡率。
T9648	SIRT1-IN-1	Antiviral; Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation
	SIRT1-IN-1 是一种选择性的 SIRT1 抑制剂，IC50 为 205 nM。 SIRT1-IN-1 是一种具有抗病毒活性的巨细胞病毒 (CMV) 抑制剂。
T15235	Enocitabine	Nucleoside Antimetabolite/Analog; HCV Protease; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Enocitabine 是一种核苷类似物，抑制 DNA 复制剂。Enocitabine 抑制人巨细胞病毒的复制，显示出抗白血病和抗病毒活性。
T14324	Artemisone BAY 44-9585,Artemifone,青蒿酮	Others; Parasite	Microbiology/Virology; Others
	Artemisone (BAY 44-9585) 是一种半合成的有效抗疟疾剂，还是一种人CMV 的有效抑制剂，可抑制多种P. falciparum，平均IC50值为 0.83 nM。
T2162	Maribavir BW1263W94,GW257406X,Benzimidavir,马立巴韦,1263W94	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Maribavir (GW257406X) 是一种可口服的苯并咪唑核苷化合物，具有抗巨细胞病毒的活性。
T7659	Bisindolylmaleimide IV	Others; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Others
	Bisindolylmaleimide IV 是一种蛋白激酶 C 细胞渗透抑制剂，其 IC50范围为 0.1-0.55 μM。它也抑制 PKA，IC50范围为3.1-11.8 μM。在细胞培养中，它有效抑制人巨细胞病毒(HCMV)复制，IC50为 0.2 μM。
T5396	Letermovir AIC246,MK-8828,莱莫维韦	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Letermovir (AIC246) 是一种新型抗 CMV 抑制剂，靶向病毒末端酶，抑制其活性。
T1533	Valganciclovir hydrochloride Valganciclovir HCl,Valcyt,缬更昔洛韦盐酸盐,Valcyte	Others; Antiviral	Immunology/Inflammation; Others
	Valganciclovir hydrochloride (Valganciclovir HCl) 是 ganciclovir 的原药，具有抗巨细胞病毒活性，可抑制病毒 DNA 聚合酶和病毒复制。
T0220	Foscarnet sodium Phosphonoformate,膦甲酸钠	Virus Protease; Reverse Transcriptase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Foscarnet sodium (Phosphonoformate) 是一种病毒 DNA 聚合酶活性抑制剂，可逆地抑制病毒复制。它是一种用于治疗巨细胞病毒性视网膜炎的抗病毒剂。
T6593	ML324	Histone Demethylase; Others; HSV	Chromatin/Epigenetic; Microbiology/Virology; Others
	ML324 是 jumonji 组蛋白去甲基化酶的特异性抑制剂，IC50值为920 nM。
TQ0095	Brincidofovir CMX001,HDP-CDV	Others; Antiviral; HSV	Immunology/Inflammation; Microbiology/Virology; Others
	Brincidofovir (HDP-CDV) 是 Cidofovir 的一种具有口服活性的亲脂性形式的前体药物，是一种口服长效的抗病毒药物，有广泛的抗 DNA 病毒活性。
T8972	FIT-039	Others; DNA/RNA Synthesis; CDK; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	FIT-039 是一种选择性和 ATP 竞争性的口服活性 CDK9 抑制剂，对CKD9/cyclin T1的IC50为 5.8 μM。它抑制HSV-1(IC50为 0.69 μM)，HSV-2，人腺病毒和人CMV 的复制。它可抑制耐药性HSV 和其他 DNA 病毒，是有前途的抗病毒药物。
T6244	Cidofovir HPMPC,GS 0504,西多福韦,(S)-HPMPC	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。
T39477	Ca-DTPA trisodium salt hydrate Ca-DTPA trisodium salt hydrate,Calcium trinatrium diethylenetriaminepentaacetic acid hydrate	Others	Others
	Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) 是螯合剂和有用的解毒剂，如急性镉中毒。它是一种无毒的 CMV 复制抑制剂。
T8736	Cidofovir dihydrate HPMPC,(S)-HPMPC,GS 0504,西多福韦二水合物	Others	Others
	Cidofovir dihydrate (HPMPC) 是注射型巨细胞病毒 DNA 聚合酶抑制剂，通过选择性抑制病毒 DNA 聚合酶来抑制 CMV 复制，从而阻止病毒复制和转录。
T0964	Floxuridine 氟尿苷,5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640	Apoptosis; Nucleoside Antimetabolite/Analog; Others; DNA/RNA Synthesis; Antibacterial; HSV	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Floxuridine (FUDR) 是一种嘧啶类似物，也是一种抗肿瘤代谢物。它抑制胸苷酸合成酶，导致 DNA 合成中断和细胞毒性。它是一种可诱导细胞凋亡的金黄色葡萄球菌感染抑制剂，具有抗HSV 和CMV 病毒的作用。
T0688	Ganciclovir BW 759,更昔洛韦,RS-21592,2'-Nor-2'-deoxyguanosine	Nucleoside Antimetabolite/Analog; Others; Antibiotic; Antifection; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Ganciclovir (2'-Nor-2'-deoxyguanosine) 是核苷类似物和口服抗病毒药物，对CMV 具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。
T22337	Ganciclovir sodium RS-21592 sodium,Cytovene IV sodium,2'-Nor-2'-deoxyguanosine sodium,BW 759 sodium,更昔洛韦钠	Nucleoside Antimetabolite/Analog; Others; Antifection; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Ganciclovir sodium (Cytovene IV sodium) 是核苷类似物和口服抗病毒药物，具有抗病毒活性，尤其是针对巨细胞病毒和单纯疱疹病毒 1 型。
T10445	B220	HSV	Microbiology/Virology
	B220 是一种能抑制 HSV-1，HSV-2 和人巨细胞病毒 (CMV) 生长的抗病毒剂。
TP1687L	CEF20 acetate(153045-21-7 free base)	Others	Others
	CEF20 acetate(153045-21-7 free base) 是 CEF 对照肽库，是来自巨细胞病毒 pp65 (495-503) 的 HLA-A*0201 限制性表位。
T67788	BAY-43-9695	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	BAY-43-9695是具有抗人巨细胞病毒(HCMV)活性的非核苷类化合物，是BAY-38-4766的主要代谢产物。
TP1822L	CEF6 acetate(913545-15-0 free base)	Influenza Virus	Microbiology/Virology
	CEF6 acetate(913545-15-0 free base) 是 HLA-B7限制性流感病毒核蛋白表位，属于 CEF 对照肽。 CEF 对照肽长度为 8-12 个氨基酸，其序列来自人类巨细胞病毒、爱泼斯坦-巴尔病毒和流感病毒。
T69390	T-0902611 benzenesulfonate	Others	Others
	T-0902611 benzenesulfonate is a cytomegalovirus replication inhibitor that may be useful in the treatment of cytomegalovirus infections.
T69396	MLS000108969	Others	Others
	MLS000108969 is a novel inhibitor of human cytomegalovirus.
T61840	pUL89 Endonuclease-IN-2	Others	Others
	pUL89 Endonuclease-IN-2 (Compound 15k) is a highly effective inhibitor of the pUL89 endonuclease of human cytomegalovirus (HCMV). With an IC50 of 3.0 μM, it exhibits potent antiviral activities [1].
T28905	T-611 free base T-0902611,T-2611,T0902611,T-902611,T2611,T-611	Others	Others
	T-611, a cytomegalovirus replication inhibitor, is used potentially for the treatment of cytomegalovirus infections.
TP1687	CEF20
	CEF20, a CEF control peptide pool, is an HLA-A0201-restricted epitope from cytomegalovirus* pp65 (495-503).
T28767	SGM8	Others	Others
	SGM8 is a covalent allosteric inhibitor of human cytomegalovirus DNA polymerase subunit Interactions.
T71066	Cidofovir sodium	Others	Others
	Cidofovir sodium is the salt form of Cidofovir, a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor that is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis in people with AIDS. The mechanism of action of cidofovir is as a DNA Polymerase Inhibitor. The chemical classification of cidofovir anhydrous is Nucleoside Analog.
T68495	Ganciclovir triphosphate	Others	Others
	Ganciclovir triphosphate is a synthetic analog of 2'-deoxy-guanosine which is used to treat or prevent cytomegalovirus (CMV) infections. It inhibits the replication of human CMV with an IC50 value of 0.01 μM and is effective against strains of CMV from human, monkey, mouse, and guinea pig.
T77146	Regavirumab
	Regavirumab (MCA C23)为针对巨细胞病毒(CMV)、人血清白蛋白(HSA)及氨基乙酸的人源单克隆抗体。
T15028	Cyclopropavir MBX-400,Filociclovir,ZSM-I-62	Others	Others
	Cyclopropavir (Filociclovir; MBX-400) is a compound of broad-spectrum anti-herpesvirus. It has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 (EC50s: 0.7 μM to 8 μM).
T70514	Ganciclovir monophosphonate	Others	Others
	Ganciclovir monophosphonate is a synthetic analog of 2'-deoxy-guanosine which is used to treat or prevent cytomegalovirus (CMV) infections. It inhibits the replication of human CMV with an IC50 value of 0.01 μM and is effective against strains of CMV from human, monkey, mouse, and guinea pig.
TP1822	CEF6
	CEF6, a HLA-B7 restricted influenza virus nucleoprotein epitope, belongs to the CEF control peptides. The CEF control peptides are 8-12 amino acids in length, with sequences derived from the human cytomegalovirus, Epstein-Barr virus and influenza virus.
T72385	LDC4297 hydrochloride	Others	Others
	LDC4297 hydrochloride为CDK7选择性抑制剂，IC50为0.13 nM。针对人巨细胞病毒(HCMV)复制展现抑制作用，EC50为24.5 nM，并对疱疹病毒、腺病毒、痘病毒、逆转录病毒及正粘病毒显示广谱抗病毒活性，EC50范围0.02-1.21 μM。适用于感染研究。
T39068	Fomivirsen sodium	Others	Others
	Fomivirsen sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein (required for viral replication), thus providing bioactive effects for CMV retinitis by inhibition of virus proliferation.
T60379	pUL89 Endonuclease-IN-1	Others	Others
	pUL89 Endonuclease-IN-1 (Compound 13d) 是人巨细胞病毒 (HCMV) pUL89 核酸内切酶的有效抑制剂，IC50值为 0.88 μM，具有抗病毒活性。
T77168	Sevirumab
	Sevirumab (MSL-109) 是一种人抗巨细胞病毒 (CMV)IgG1中和单克隆抗体。Sevirumab 识别CMVgH 复合物，抑制CMV 复制，EC50为 0.3 μg/mL。
T82701	CMV pp65(13-27)
	CMVpp65(13-27)是一种源自人巨细胞病毒65k下层基质磷蛋白的氨基酸残基13至27的生物活性肽。它含有的九个氨基酸序列(LGPISGHVL)与主要组织相容性复合物H2-Dd T细胞表位的共有结合基序匹配。
T60419	Cyclic HPMPC	Others	Others
	Cyclic HPMPC 是有效的抗病毒剂，可以增加感染致死性牛痘苗病毒 (IHD 株) 小鼠的动脉氧饱和度水平。用 Cyclic HPMPC 治疗可改善先天性豚鼠巨细胞病毒 (GPCMV) 感染的结果并减少豚鼠模型中的病毒复制。
T77010	Fiztasovimab
	Fiztasovimab (NPC-21; EV2038) 是一种全人 IgG1λ 单克隆抗体，具有抗人巨细胞病毒 (hCMV) 活性。Fiztasovimab 通过结合 hCMV 包膜上糖蛋白 B 的抗原结构域 1 发挥中和活性。Fiztasovimab 还抑制 hCMV 的细胞间传播。
T73983	Cidofovir diphosphate tri(triethylamine)	Others	Others
	Cidofovir diphosphate tri triethylamine 是西多福韦的细胞内活性代谢物。diphosphate tri triethylamine 是病毒 DNA 聚合酶的选择性抑制剂，对 HCMV，HSV-1和 HSV-2的 Ki 值分别为 6.6，0.86 和 1.4 μM。
T60488	Ganciclovir hydrate	Others	Others
	Ganciclovir (BW 759) hydrate 是一种核苷类似物，是具有口服活性的抗病毒剂，显示出抗巨细胞病毒活性。Ganciclovir hydrate 对疱疹病毒和其他一些 DNA 病毒也具有体外抗病毒活性。Ganciclovir hydrate 在体外抑制人类疱疹病毒 (HSV 1 型和 2 型，CMV) 和腺病毒血清型1、2、4、6、8、10、19、22 和 28 的复制。Ganciclovir hydrate 对猫疱疹病毒 1 型 (FHV-1) 的 IC50为 5.2 μM，可扩散到大脑。
T61259	Valganciclovir	Others	Others
	Valganciclovir 是ganciclovir 的原药，具有抗巨细胞病毒CMV 感染的活性。
T36673	CC 401 dihydrochloride	Others	Others
	High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of active, phosphorylated JNK. Exhibits > 40-fold selectivity for JNK over p38, ERK, IKK2, protein kinase C, Lck and ZAP70. Hepatoprotective. Also inhibits HCMV replication. Uehara et al (2004) c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation. Transplantation. 78 324 PMID:15316358 \|Uehara et al (2005) JNK mediates hepatic ischemia reperfusion injury. J...

化合物

Cat.No: T0718

Synonym: Bromovinyldeoxyuridine,BVDU,溴夫定

Target: Others, HSV

Cat.No: T38514

Target: Others, HIV Protease

Cat.No: T9648

Target: Antiviral, Sirtuin

Cat.No: T15235

Target: Nucleoside Antimetabolite/Analog, HCV Protease, DNA/RNA Synthesis

Cat.No: T14324

Synonym: BAY 44-9585,Artemifone,青蒿酮

Target: Others, Parasite

Cat.No: T2162

Synonym: BW1263W94,GW257406X,Benzimidavir,马立巴韦,1263W94

Target: Others, HCV Protease

Bisindolylmaleimide IV

Cat.No: T7659

Target: Others, PKC

Cat.No: T5396

Synonym: AIC246,MK-8828,莱莫维韦

Target: Others, HCV Protease

Valganciclovir hydrochloride

Cat.No: T1533

Synonym: Valganciclovir HCl,Valcyt,缬更昔洛韦盐酸盐,Valcyte

Target: Others, Antiviral

Foscarnet sodium

Cat.No: T0220

Synonym: Phosphonoformate,膦甲酸钠

Target: Virus Protease, Reverse Transcriptase, DNA/RNA Synthesis

Cat.No: T6593

Target: Histone Demethylase, Others, HSV

Cat.No: TQ0095

Synonym: CMX001,HDP-CDV

Target: Others, Antiviral, HSV

Cat.No: T8972

Target: Others, DNA/RNA Synthesis, CDK, HSV

Cat.No: T6244

Synonym: HPMPC,GS 0504,西多福韦,(S)-HPMPC

Target: Others, DNA/RNA Synthesis

Ca-DTPA trisodium salt hydrate

Cat.No: T39477

Synonym: Ca-DTPA trisodium salt hydrate,Calcium trinatrium diethylenetriaminepentaacetic acid hydrate

Target: Others

Cidofovir dihydrate

Cat.No: T8736

Synonym: HPMPC,(S)-HPMPC,GS 0504,西多福韦二水合物

Target: Others

Cat.No: T0964

Synonym: 氟尿苷,5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Others, DNA/RNA Synthesis, Antibacterial, HSV

Cat.No: T0688

Synonym: BW 759,更昔洛韦,RS-21592,2'-Nor-2'-deoxyguanosine

Target: Nucleoside Antimetabolite/Analog, Others, Antibiotic, Antifection, HSV

Ganciclovir sodium

Cat.No: T22337

Synonym: RS-21592 sodium,Cytovene IV sodium,2'-Nor-2'-deoxyguanosine sodium,BW 759 sodium,更昔洛韦钠

Target: Nucleoside Antimetabolite/Analog, Others, Antifection, HSV

Cat.No: T10445

Target: HSV

CEF20 acetate(153045-21-7 free base)

Cat.No: TP1687L

Target: Others

Cat.No: T67788

Target: HCV Protease

CEF6 acetate(913545-15-0 free base)

Cat.No: TP1822L

Target: Influenza Virus

T-0902611 benzenesulfonate

Cat.No: T69390

Target: Others

Cat.No: T69396

Target: Others

pUL89 Endonuclease-IN-2

Cat.No: T61840

Target: Others

T-611 free base

Cat.No: T28905

Synonym: T-0902611,T-2611,T0902611,T-902611,T2611,T-611

Target: Others

Cat.No: TP1687

Cat.No: T28767

Target: Others

Cidofovir sodium

Cat.No: T71066

Target: Others

Ganciclovir triphosphate

Cat.No: T68495

Target: Others

Cat.No: T77146

Cat.No: T15028

Synonym: MBX-400,Filociclovir,ZSM-I-62

Target: Others

Ganciclovir monophosphonate

Cat.No: T70514

Target: Others

Cat.No: TP1822

LDC4297 hydrochloride

Cat.No: T72385

Target: Others

Fomivirsen sodium

Cat.No: T39068

Target: Others

pUL89 Endonuclease-IN-1

Cat.No: T60379

Target: Others

Cat.No: T77168

CMV pp65(13-27)

Cat.No: T82701

Cat.No: T60419

Target: Others

Cat.No: T77010

Cidofovir diphosphate tri(triethylamine)

Cat.No: T73983

Target: Others

Ganciclovir hydrate

Cat.No: T60488

Target: Others

Cat.No: T61259

Target: Others

CC 401 dihydrochloride

Cat.No: T36673

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1068	Tricin	Others; CDK	Cell Cycle/Checkpoint; Others
	Tricin 是米糠中大量存在的一种天然类黄酮。它通过抑制 CDK9 来抑制HCMV 的复制。它通过上调 FAK 靶向 microRNA-7 的表达来抑制 C6 胶质瘤细胞的增殖和侵袭。
T3342	Xanthohumol	Apoptosis; Others; Influenza Virus; COX; Acyltransferase; HSV	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; Others
	Xanthohumol 是从啤酒花中分离到的黄酮类化合物，可抑制 COX-1 和 COX-2 活性，具有抗肿瘤，抗血管生成的作用，还具有抗多种病毒的活性。
T1591	Ancitabine hydrochloride NSC 145668 HCl,盐酸环胞苷,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C	Others; DNA/RNA Synthesis; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Ancitabine hydrochloride (NSC 145668 HCl) 是一种天然的抗白血病药物。
TN2231	Soyasaponin II	Influenza Virus; HIV Protease; HSV	Microbiology/Virology; Proteases/Proteasome
	Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.

天然产物

Cat.No: TN1068

Target: Others, CDK

Cat.No: T3342

Target: Apoptosis, Others, Influenza Virus, COX, Acyltransferase, HSV

Ancitabine hydrochloride

Cat.No: T1591

Synonym: NSC 145668 HCl,盐酸环胞苷,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C

Target: Others, DNA/RNA Synthesis, Autophagy

Cat.No: TN2231

Target: Influenza Virus, HIV Protease, HSV

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00811	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein Human cytωlovirus (HCMV) Glycoprotein B/gB	CMV	HEK293 Cells
	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 92 kDa and the accession number is P13201.
TMPY-01201	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His) Human cytωlovirus (HCMV) Glycoprotein B/gB	CMV	HEK293 Cells
	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 93.2 kDa and the accession number is P13201.
TMPY-00810	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (hFc) Human cytωlovirus (HCMV) Glycoprotein B/gB	CMV	HEK293 Cells
	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 118 kDa and the accession number is P13201.
TMPH-01195	Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog UL111A,Viral interleukin-10 homolog	HCMV	E. coli
	Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog ...
TMPY-00054	Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) Macaca fascicularis Cytωlovirus (CyCMV) (strain OT-1) glycop...	CyCMV	HEK293 Cells
	Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 102.5 kDa and the accession number is E7DB34.
TMPY-00812	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (aa 1-700, hFc) Human cytωlovirus (HCMV) Glycoprotein B/gB	CMV	HEK293 Cells
	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (aa 1-700, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 104 kDa and the accession number is P13201.
TMPH-01193	Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His) Uncharacterized protein UL128,UL128	HHV-5	E. coli
	Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His) is expressed in E. coli.
TMPH-01190	Human cytomegalovirus (HCMV) (strain AD169) glycoprotein H/gH Protein (His & SUMO) gH,Envelope glycoprotein H	HHV-5	E. coli
	Human cytomegalovirus (HCMV) (strain AD169) glycoprotein H/gH Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.8 kDa and the accession number is P12824.
TMPH-01194	Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO) UL130,Uncharacterized protein UL130	HHV-5	E. coli
	Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37....
TMPH-01191	Human cytomegalovirus (HCMV) (strain Towne) glycoprotein UL132 Protein (Avi & His & MBP), Biotinylated UL132,Envelope glycoprotein UL132	HHV-5	E. coli
	Human cytomegalovirus (HCMV) (strain Towne) glycoprotein UL132 Protein (Avi & His & MBP), Biotinylated is expressed in E. coli.
TMPH-01192	Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated Phosphoprotein UL32,150 kDa matrix phosphoprotein,Tegument p...	HHV-5	E. coli
	Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated is expressed in E. coli.
TMPH-03406	Rhesus cytomegalovirus (RhCMV) (strain 68-1) Glycoprotein B/gB Protein (His & Myc) gB,Envelope glycoprotein B	RhCMV	E. coli
	Rhesus cytomegalovirus (RhCMV) (strain 68-1) Glycoprotein B/gB Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.0 kDa and the accession number is P89053.
TMPJ-00993	CCL5 Protein, Rat, Recombinant (E. coli, His) Small-inducible cytokine A5,SIS-δ,C-C motif chemokine 5,T-ce...	Rat	E. coli
	C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory sites, and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. Inflammatory responses can be impaired by the sequestration of CCL5 by the cytomegalovirus protein US28. Oligomerization of CCL5 on glycosaminoglycans is required for CCR1mediated leu...
TMPJ-00131	NKG2DL Protein, Human, Recombinant (hFc) ALCAN-β,NKG2DL1,UL16-binding protein 1,NKG2D ligand 1,ULBP1,...	Human	HEK293 Cells
	NKG2D ligand 1, also called ULBP1, is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC molecules possess α1, α2 and α3 domains, ULBP/RAET1 family members lack α3 domain. ULBP1 is recognized by the activating receptor NKG2D on the surface of cytotoxic natural killer (NK) and T cells, and then promotes the lysis of cells expressing ULBP1 which is important for the im...
TMPH-01524	KPNA1 Protein, Human, Recombinant (His) Nucleoprotein interactor 1,SRP1-beta,Karyopherin subunit alp...	Human	E. coli
	Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta ...
TMPY-02210	Serpin B9 Protein, Human, Recombinant (His) CAP-3,PI-9,CAP3,PI9,serpin peptidase inhibitor, clade B (ova...	Human	Baculovirus Insect Cells
	SerpinB9, also known as Cytoplasmic antiproteinase 3, CAP-3, Peptidase inhibitor 9, SERPINB9 and PI-9, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. Serpin-B9 ( CAP-3 / PI-9 ) is the only known human intracellular inhibitor of granzyme B (GrB), the effector molecule in immunity against cytomegalovirus (CMV) and in renal allograft rejection. Serpin-B9 and SPI-6 expression in immune-privileged cells, APCs, and CTLs protect these cells against the actions of gran...

重组蛋白

Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein

Cat.No: TMPY-00811

Species: CMV

Expression System: HEK293 Cells

Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His)

Cat.No: TMPY-01201

Species: CMV

Expression System: HEK293 Cells

Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (hFc)

Cat.No: TMPY-00810

Species: CMV

Expression System: HEK293 Cells

Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog

Cat.No: TMPH-01195

Species: HCMV

Expression System: E. coli

Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc)

Cat.No: TMPY-00054

Species: CyCMV

Expression System: HEK293 Cells

Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (aa 1-700, hFc)

Cat.No: TMPY-00812

Species: CMV

Expression System: HEK293 Cells

Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His)

Cat.No: TMPH-01193

Species: HHV-5

Expression System: E. coli

Human cytomegalovirus (HCMV) (strain AD169) glycoprotein H/gH Protein (His & SUMO)

Cat.No: TMPH-01190

Species: HHV-5

Expression System: E. coli

Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO)

Cat.No: TMPH-01194

Species: HHV-5

Expression System: E. coli

Human cytomegalovirus (HCMV) (strain Towne) glycoprotein UL132 Protein (Avi & His & MBP), Biotinylated

Cat.No: TMPH-01191

Species: HHV-5

Expression System: E. coli

Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated

Cat.No: TMPH-01192

Species: HHV-5

Expression System: E. coli

Rhesus cytomegalovirus (RhCMV) (strain 68-1) Glycoprotein B/gB Protein (His & Myc)

Cat.No: TMPH-03406

Species: RhCMV

Expression System: E. coli

CCL5 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPJ-00993

Species: Rat

Expression System: E. coli

NKG2DL Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00131

Species: Human

Expression System: HEK293 Cells

KPNA1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01524

Species: Human

Expression System: E. coli

Serpin B9 Protein, Human, Recombinant (His)

Cat.No: TMPY-02210

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0306	Ganciclovir-d5
	Ganciclovir-d5 是 Ganciclovir 的氘代化合物。Ganciclovir 的 CAS 号为 82410-32-0。Ganciclovir是核苷类似物和口服抗病毒药物，对CMV具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。

同位素标记化合物

Cat.No: TMIJ-0306

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