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Search Results for " cypd "
Targets Recommended: Others

6

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T27110 CypD inhibitor C-9

CypD inhibitor C 9

Others Others
CypD inhibitor C-9 is a CypD inhibitor, it attenuates mitochondrial and cellular perturbation insulted by Aß and calcium stress.
T71997 CypD-IN-29

Others Others
CypD-IN-29 is a non-peptidic inhibitor of cyclophilin D as a neuroprotective agent in Aβ-induced mitochondrial dysfunction.
T74963 CypD-IN-3

Others Others
CypD-IN-3是一种高效的CypD (亲环蛋白D) 选择性抑制剂,其对CypD的IC50值仅为0.01 μM。该化合物在氧化应激、神经退行性疾病、肝病、衰老、自噬及糖尿病等多种疾病的研究中有潜在应用。
T74964 CypD-IN-4

Others Others
CypD-IN-4是一种针对亲环蛋白D(CypD)的有效亚型选择性抑制剂,展现出0.057 μM的IC50,表明其对CypD具有高度亲和力。该化合物适用于氧化应激、神经退行性疾病、肝病、衰老、自噬及糖尿病等多种疾病的研究。
T71432 MDL-27088

Others Others
MDL-27088 is an angiotensin-covering enzyme inhibitor.
T74965 CypE-IN-1

Others Others
CypD-IN-1 是一种有效的亚型选择性亲环蛋白 E (CypE) 抑制剂。CypD-IN-1 具有 CypE 亲和力,IC50和 Ki 值分别为 0.013 μM 和 0.072 μM。CypD-IN-1 可用于多种疾病的研究,如氧化应激、神经退行性疾病、肝病、衰老、自噬和糖尿病。

化合物

CypD inhibitor C-9
Cat.No: T27110
Synonym: CypD inhibitor C 9
Target: Others
CypD-IN-29
Cat.No: T71997
Synonym:
Target: Others
CypD-IN-3
Cat.No: T74963
Synonym:
Target: Others
CypD-IN-4
Cat.No: T74964
Synonym:
Target: Others
MDL-27088
Cat.No: T71432
Synonym:
Target: Others
CypE-IN-1
Cat.No: T74965
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T5S1133 Ganoderic acid D

灵芝酸D,灵芝酸 D

Apoptosis; Sirtuin Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
Ganoderic acid D 是高度氧化的四环三萜,是灵芝的主要活性成分,可诱导 HeLa 人宫颈癌细胞凋亡。它上调 SIRT3的蛋白质表达并通过 SIRT3 诱导脱乙酰化的亲环蛋白 D 。它抑制结肠癌细胞的能量重编程,包括结肠癌细胞中的葡萄糖摄取,乳酸、丙酮酸和乙酰辅酶的产生。

天然产物

Ganoderic acid D
Cat.No: T5S1133
Synonym: 灵芝酸D,灵芝酸 D
Target: Apoptosis, Sirtuin
Cat. No. Product Name Species Expression System
TMPY-00156 Cyclophilin F Protein, Human, Recombinant (His)

peptidylprolyl isomerase F,CYP3,Cyp-D,CyP-M,CypD

Human HEK293 Cells
Cyclophilin F Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A0A024QZS4.
TMPJ-01090 PPID Protein, Human, Recombinant (His)

Cyclophilin-40,CYPD,Peptidyl-Prolyl Cis-Trans Isome...

Human E. coli
Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.

重组蛋白

Cyclophilin F Protein, Human, Recombinant (His)
Cat.No: TMPY-00156
Species: Human
Expression System: HEK293 Cells
PPID Protein, Human, Recombinant (His)
Cat.No: TMPJ-01090
Species: Human
Expression System: E. coli
TargetMol Loading
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