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Search Results for " coumarin "

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抑制剂 & 化合物

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同位素标记化合物

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Cat. No.	Product Name
L6100	天然多酚类化合物库		635 compounds
	635 个天然多酚化合物的独特集合，可用于高通量、高内涵筛选；

化合物库

天然多酚类化合物库

Cat.No: L6100

Compounds: 635

Cat. No.	Product Name	Target	Signaling Pathways
T36105	coumarin-SAHA coumarin-Suberoylanilide Hydroxamic Acid,coumarin-SAHA	Others	Others
	Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. [1] coumarin-Suberoylanilide hydroxamic acid (c-SAHA) is a SAHA derivative where the anilino cap" group is replaced by 7-amino-4-methylcoumarin to produce a fluorescent probe that competitively binds HDAC. [2] The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm
T31017	Coumarin-TMP-Halo Coumarin TMP Halo,CTH	Others	Others
	Coumarin-TMP-Halo is a specific fluorescent protein labeling agent.
T5845	7ACC1 DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421	Monocarboxylate transporter	Membrane transporter/Ion channel
	7ACC1 (D 142) 抑制表达MCT1和MCT4肿瘤细胞的乳酸涌入，能选择性干扰肿瘤微环境乳酸通量。
T117521	7-BFC 7-Benzyloxy-4-(trifluoromethyl)coumarin,Y040-0031	P450	Metabolism
	7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) 是一种香豆素类荧光底物，可作为细胞色素 P 450 的生物标记物，可用于研究 CYP 亚型和细胞色素 P 450 代谢。
T38324	Coumarin Boronic Acid	Others	Others
	Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide.It reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively.
T37797	Coumarin-Quinone Conjugate	Others	Others
	Coumarin-quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases.1It is comprised of a coumarin fluorophore conjugated to a ubiquinone analog that can be reduced by NADH:ubiquinone oxidoreductases. It has been used to measure the kinetic parameters of apoptosis-inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1). 1.Doll, S., Freitas, F.P., Shah, R., et al.FSP1 is a glutathione-independent ferroptosis suppressorNature575(7784)693-698(20...
T38325	Coumarin Boronic Acid pinacolate ester	Others	Others
	Coumarin boronic acid pinacolate ester (CBE) is a more soluble form of coumarin boronic acid that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide. Peroxynitrite oxidizes CBE into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively.
T37926	7-Ethoxy-4-(trifluoromethyl)coumarin
	7-Ethoxy-5-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs).1Upon O-deethylation by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively. 1.Buters, J.T.M., Schiller, C.D., and Chou, R.C.A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation o...
T37365	7-hydroxy Coumarin sulfate (potassium salt)	Others	Others
	7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS.
T37364	7-hydroxy Coumarin Glucuronide (sodium salt)	Others	Others
	7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.
T31015	Coumarin, 3-glyoxyloyl- 3-Glyoxylcoumaric aldehyde,3-Glyoxyloylcoumarin,Aldeide cumarin-3-gliossilica	Others	Others
	Coumarin, 3-glyoxyloyl-, is a coumarin analogue for treatment of various diseases. Substituting new functional groups at different positions of coumarin nucleus may be useful in the development of novel compounds for the treatment of cancer.
T31016	Coumarin, 3-glyoxyloyl-8-methoxy- 3-Glyoxyloyl-8-methoxycoumarin,3-Glyoxyl-8-methoxycoumaric aldehyde	Others	Others
	Coumarin, 3-glyoxyloyl-8-methoxy- is a coumarin analogue for treatment of various diseases. Substituting new functional groups at different positions of coumarin nucleus may be useful in the development of novel compounds for the treatment of cancer.
T82679	Coumarin hydrazine
	Coumarin hydrazine，作为荧光化学探针（λex=420-450 /λem=468 nm），专用于细胞内蛋白质和脂质结合羰基的标记。
T66908	Coumarin 314
	Coumarin 314 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66908，CAS号为 55804-66-5。
T82675	Coumarin-PEG3-TCO
	Coumarin-PEG3-TCO，一种含有3个PEG单元的香豆素衍生物，通过其TCO基团参与与含有四唑基团的分子的逆电子需求Diels-Alder反应(iEDDA)发挥作用。
T82677	Coumarin-C2-TCO
	Coumarin-C2-TCO，作为Coumarin的染料衍生物，通过其TCO基团能够与带有四嗪基团的分子发生逆电子需求Diels-Alder反应(iEDDA)。
T82674	Coumarin-PEG8-tetrazine
	Coumarin-PEG8-tetrazine是一种含有8个PEG单元的Coumarin衍生物。该化合物具有一个Tetrazine基团，能够与含有TCO基团的分子发生逆电子需求Diels-Alder反应(iEDDA)。
T82676	Coumarin-PEG2-TCO
	Coumarin-PEG2-TCO是一种含有2个PEG单元的香豆素衍生物。该化合物的TCO基团可通过逆电子需求Diels-Alder反应（iEDDA）与含有四唑基团的分子反应。
T123943	6,7-Bis(benzyloxy)coumarin	Others	Others
	6,7-Bis(benzyloxy)coumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T123943，CAS号为 909-84-2。
T82678	Coumarin-C2-exo-BCN
	Coumarin-C2-exoBCN是一种Coumarin染料衍生物。该化合物含有亲脂性双齿大环配体exo-BCN，可用于合成大环复合物。在点击化学中，exo-BCN能在无催化剂条件下与含有叠氮基团的分子发生反应，生成稳定的三唑。
T18933	Calcein Blue	Others	Others
	Calcein Blue 是含有亚氨基二乙酸结构的香豆素衍生物，是不渗透膜的荧光染料，也是金属荧光变色指示剂。
T77557	Coumarin343
	Coumarin343对单羧酸转运蛋白 4有抑制作用，IC50值在0.01-100 µM。Coumarin343具有抗癌和抗菌活性。Coumarin343是一种香豆素染料。
T77674	3-Cyano-7-hydroxycoumarin 3-Cyanoumbelliferone
	3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) 是一种巨噬细胞游走抑制因子 (MIF) 互变异构酶抑制剂，Ki 为 2.9 μM。3-Cyano-7-hydroxycoumarin 属于香豆素衍生物，可被用作分子探针和荧光染料。
T77558	5,7-Dimethoxy-4-methylcoumarin	Antioxidant	oxidation-reduction
	5,7-Dimethoxy-4-methylcoumarin 具有潜在的抗氧化抗增殖和抗癌或活性。
T10115	3-Nitrocoumarin 3-nitrochromen-2-one	Phospholipase	Metabolism
	3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) 是一个有效的、磷脂酶 C-γ (PLC-γ) 的选择性抑制剂。
T7037	7-Acetoxy-4-methylcoumarin 7-乙酰氧基-4-甲基香豆素,MU-Ac	Others; GST	Others; oxidation-reduction
	7-Acetoxy-4-methylcoumarin 是羧酸酯酶的荧光底物，可作为一种 GST 的抑制剂，可从 Trigonella foenum graceum 中分离出来，抑制 AFB1-DNA 结合。
T8677	3,4 Dichloroisocoumarin	Others; Serine Protease; Cysteine Protease	Others; Proteases/Proteasome
	3,4 Dichloroisocoumarin 是一种颗粒酶、组织蛋白酶 G 和中性粒细胞弹性蛋白酶抑制剂
T77564	Coumarin102 Exciton 480
	Coumarin102 (Exciton 480)是一种荧光染料。Coumarin102对Monoamine oxidase B、MAO-B和MAO-A具有较弱的抑制活性，可用来研究神经系统疾病。
T7696	3-Cyano-7-ethoxycoumarin	Others	Others
	3-Cyano-7-ethoxycoumarin 是荧光色素 P-450底物，在酶切时获得蓝色荧光产物。
TD0078	Succinimidyl 7-methoxycoumarin-3-carboxylate 7-甲氧基-3-羧基香豆素琥珀酰亚胺酯,7-Methoxycoumarin-3-carboxylic acid, succinimidyl ester
	7-Methoxycoumarin-3-carboxylic acid may be used as a reference compound in the purification, separation and analysis of coumarin compounds.
TD0075	7-Hydroxy-4-methylcoumarin-3-acetic acid
	7-Hydroxy-4-methylcoumarin-3-acetic acid is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. This coumarin is increasingly used to label peptides, nucleotides and carbohydrates.
T83363	3-Acetyl-6-bromocoumarin	Others	Others
	3-Acetyl-6-bromocoumarin，一种香豆素，具有约56%的强抗氧化活性。
T83256	7-(Dimethylamino)-4-methylcoumarin	Others	Others
	7-(Dimethylamino)-4-methylcoumarin，一种香豆素，主要用于香豆素荧光增白剂溶液研究。
TD0074	N-Succinimidyl 7-hydroxycoumarin-3-carboxylate 7-羟基-3-羧基香豆素琥珀酰亚胺酯,7-Hydroxycoumarin-3-carboxylic acid, succinimidyl ester
	7-Hydroxycoumarin-3-carboxylic acid, SE is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. This coumarin is also increasingly used to label peptides, nucleotides and carbohydrates.
T37000	7-Azido-4-methylcoumarin	Others	Others
	7-Azido-4-methylcoumarin (AzMC) is a coumarin fluorescent probe for hydrogen sulfide (H2S).1 AzMC selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species. AzMC displays excitation/emission maxima of 340/445 nm, respectively. \|1. Chen, B., Li, W., Lv, C., et al. Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues. Analyst 138(3), 946-951 (2013).
T83250	7-Acetoxy-4-bromomethylcoumarin
	7-Acetoxy-4-bromomethylcoumarin是作为脂肪酸新型荧光探针。
T32784	Liqcoumarin	Others	Others
	Liqcoumarin 属于羟基香豆素类。在细胞内，它主要位于细胞质中。在人体外，它可以在草药、香料和茶中找到。这使得Liqcoumarin 成为这些食品消费的潜在生物标志物。
T83324	4-Bromomethyl-6,7-dimethoxycoumarin
	4-Bromomethyl-6,7-dimethoxycoumarin 作为羧酸在色谱检测中的荧光标记物使用。
TD0073	7-Hydroxycoumarin-3-carboxylic acid
	7-Hydroxycoumarin-3-carboxylic acid is a blue fluorophores for labeling proteins and nucleic acids mostly through the in situ formation of its succinimidyl ester catalyzed by EDAC.
T29485	7-Lysylalanyl-4-methylcoumarinamide	Others	Others
	7-Lysylalanyl-4-methylcoumarinamide is a Fluorogenic substrate for dipeptidyl aminopeptidase.
T124649	5,6,7,8-Tetramethoxycoumarin	Others	Others
	5,6,7,8-Tetramethoxycoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124649。
T40888	3-Acetamidocoumarin	Others	Others
	3-Acetamidocoumarin, a compound significant in biology and medicine, exhibits physiological effects and is utilized in treating various conditions, including burns, brucellosis-rheumatic diseases, and cancer.
T130450	3,4,8-Trihydroxycoumarin	Others	Others
	3,4,8-Trihydroxycoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T130450。
T125085	5-Methoxy-7-hydroxycoumarin	Others	Others
	5-Methoxy-7-hydroxycoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125085。
T124089	Preethuliacoumarin	Others	Others
	Preethuliacoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124089，CAS号为 85431-45-4。
T67631	4,6-Dimethyl-7-ethylaminocoumarin
	4,6-Dimethyl-7-ethylaminocoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67631，CAS号为 26078-25-1。
T83249	7-Aminocoumarin
	7-Aminocoumarin，高荧光性化合物，用于荧光增白及探针应用。
T126231	6,8-Dihydroxy-3-methylisocoumarin	Others	Others
	6,8-Dihydroxy-3-methylisocoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126231，CAS号为 1204-37-1。
T123948	6,8-Di-O-methylcitreoisocoumarin	Others	Others
	6,8-Di-O-methylcitreoisocoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T123948。
T125251	8-Geranyl-7-hydroxycoumarin	Others	Others
	8-Geranyl-7-hydroxycoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125251，CAS号为 23660-05-1。

化合物

coumarin-SAHA

Cat.No: T36105

Synonym: coumarin-Suberoylanilide Hydroxamic Acid,coumarin-SAHA

Target: Others

Coumarin-TMP-Halo

Cat.No: T31017

Synonym: Coumarin TMP Halo,CTH

Target: Others

Cat.No: T5845

Synonym: DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421

Target: Monocarboxylate transporter

Cat.No: T117521

Synonym: 7-Benzyloxy-4-(trifluoromethyl)coumarin,Y040-0031

Target: P450

Coumarin Boronic Acid

Cat.No: T38324

Target: Others

Coumarin-Quinone Conjugate

Cat.No: T37797

Target: Others

Coumarin Boronic Acid pinacolate ester

Cat.No: T38325

Target: Others

7-Ethoxy-4-(trifluoromethyl)coumarin

Cat.No: T37926

7-hydroxy Coumarin sulfate (potassium salt)

Cat.No: T37365

Target: Others

7-hydroxy Coumarin Glucuronide (sodium salt)

Cat.No: T37364

Target: Others

Coumarin, 3-glyoxyloyl-

Cat.No: T31015

Synonym: 3-Glyoxylcoumaric aldehyde,3-Glyoxyloylcoumarin,Aldeide cumarin-3-gliossilica

Target: Others

Coumarin, 3-glyoxyloyl-8-methoxy-

Cat.No: T31016

Synonym: 3-Glyoxyloyl-8-methoxycoumarin,3-Glyoxyl-8-methoxycoumaric aldehyde

Target: Others

Coumarin hydrazine

Cat.No: T82679

Cat.No: T66908

Coumarin-PEG3-TCO

Cat.No: T82675

Coumarin-C2-TCO

Cat.No: T82677

Coumarin-PEG8-tetrazine

Cat.No: T82674

Coumarin-PEG2-TCO

Cat.No: T82676

6,7-Bis(benzyloxy)coumarin

Cat.No: T123943

Target: Others

Coumarin-C2-exo-BCN

Cat.No: T82678

Cat.No: T18933

Target: Others

Cat.No: T77557

3-Cyano-7-hydroxycoumarin

Cat.No: T77674

Synonym: 3-Cyanoumbelliferone

5,7-Dimethoxy-4-methylcoumarin

Cat.No: T77558

Target: Antioxidant

3-Nitrocoumarin

Cat.No: T10115

Synonym: 3-nitrochromen-2-one

Target: Phospholipase

7-Acetoxy-4-methylcoumarin

Cat.No: T7037

Synonym: 7-乙酰氧基-4-甲基香豆素,MU-Ac

Target: Others, GST

3,4 Dichloroisocoumarin

Cat.No: T8677

Target: Others, Serine Protease, Cysteine Protease

Cat.No: T77564

Synonym: Exciton 480

3-Cyano-7-ethoxycoumarin

Cat.No: T7696

Target: Others

Succinimidyl 7-methoxycoumarin-3-carboxylate

Cat.No: TD0078

Synonym: 7-甲氧基-3-羧基香豆素琥珀酰亚胺酯,7-Methoxycoumarin-3-carboxylic acid, succinimidyl ester

7-Hydroxy-4-methylcoumarin-3-acetic acid

Cat.No: TD0075

3-Acetyl-6-bromocoumarin

Cat.No: T83363

Target: Others

7-(Dimethylamino)-4-methylcoumarin

Cat.No: T83256

Target: Others

N-Succinimidyl 7-hydroxycoumarin-3-carboxylate

Cat.No: TD0074

Synonym: 7-羟基-3-羧基香豆素琥珀酰亚胺酯,7-Hydroxycoumarin-3-carboxylic acid, succinimidyl ester

7-Azido-4-methylcoumarin

Cat.No: T37000

Target: Others

7-Acetoxy-4-bromomethylcoumarin

Cat.No: T83250

Cat.No: T32784

Target: Others

4-Bromomethyl-6,7-dimethoxycoumarin

Cat.No: T83324

7-Hydroxycoumarin-3-carboxylic acid

Cat.No: TD0073

7-Lysylalanyl-4-methylcoumarinamide

Cat.No: T29485

Target: Others

5,6,7,8-Tetramethoxycoumarin

Cat.No: T124649

Target: Others

3-Acetamidocoumarin

Cat.No: T40888

Target: Others

3,4,8-Trihydroxycoumarin

Cat.No: T130450

Target: Others

5-Methoxy-7-hydroxycoumarin

Cat.No: T125085

Target: Others

Preethuliacoumarin

Cat.No: T124089

Target: Others

4,6-Dimethyl-7-ethylaminocoumarin

Cat.No: T67631

7-Aminocoumarin

Cat.No: T83249

6,8-Dihydroxy-3-methylisocoumarin

Cat.No: T126231

Target: Others

6,8-Di-O-methylcitreoisocoumarin

Cat.No: T123948

Target: Others

8-Geranyl-7-hydroxycoumarin

Cat.No: T125251

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0775	Coumarin	Factor Xa; Influenza Virus	Metabolism; Microbiology/Virology
	Coumarin 是中国北沙参中的一种主要生物活性成分，具有抗癌、抗炎和抗病毒等活性。它作为几种抗凝剂的前体具有临床价值，尤其是华法林。
TN1529	Coumarin 6 Coumarin VI,香豆素 6	Others	Others
	Coumarin 6 (Coumarin VI) 是一种荧光染料，可作为微粒给药系统中的荧光探针，研究药物给药系统的体内跟踪、细胞摄取和转运机制。
TJS0341	7-Amino-4-(trifluoromethyl)coumarin 香豆素151,Coumarin 151,AFC,7-氨基-4-（三氟甲基）香豆素	5-HT Receptor	GPCR/G Protein; Neuroscience
	7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是一种荧光标记物，其激发和发射波长分别为400和500 nm，可用来灵敏的检测蛋白酶。
T7960	Coumarin 7 香豆素-7,香豆素7	Others	Others
	Coumarin 7 是一种在植物中以糖苷的形式存在的香豆素激光染料。
TJS0339	Coumarin-3-carboxylic acid 香豆素-3-羧酸,3-Carboxycoumarin	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Coumarin-3-carboxylic acid (3-Carboxycoumarin) 是一种合成香豆素的重要起始化合物。其中香豆素是具有多种生物活性的天然产物。它的镧系复合物对 K-562 细胞具有抗增殖活性。
T2909	Fraxetin 7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀	Apoptosis; Others	Apoptosis; Others
	Fraxetin (7,8-dihydroxy-6-methoxy coumarin) 是从秦皮中分离出来的一种天然产物，可诱导细胞凋亡，具有抗肿瘤、抗氧化作用和抗炎作用。
TN1243	3-Aminocoumarin 3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine	Others	Others
	3-Aminocoumarin (3-aminochromen-2-one) 是金属配合物的关键中间体。
TN6209	7-(3'-Carboxybutoxy)coumarin
	7-(3'-Carboxybutoxy)coumarin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6209，CAS号为 16851-01-7。
TJS0311	Ethyl 3-coumarincarboxylate 3-Ethoxycarbonylcoumarin,香豆素-3-羧酸乙酯,香豆素-3-羧酸乙素,Ethyl 2-Oxo-2H-Chromene-3-Carboxylate,Ethyl coumarin-3-carboxylate,3-Carbethoxycoumarin	Others	Others
	Ethyl coumarin-3-carboxylate 是香豆素衍生物。它可作为一种伪模板，制备能够特异性识别黄曲霉毒素的分子印迹聚合物 (MIP)。
TN2024	Oxyimperatorin	Others	Others
	Oxyimperatorin 是一种香豆素，分离自当归。
TN6207	7-(6'R-hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin
	7-(6'R-hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6207，CAS号为 118584-19-3。
T37345	5,7-Dihydroxycoumarin	Antibacterial	Microbiology/Virology
	5,7-Dihydroxycoumarin 是分离自Macaranga triloba 花序的香豆素，具有抗菌活性。
TN1120	Osthenol	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Osthenol 是一种前酰化香豆素，从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用，IC50=0.74 µM，对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的，选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。
T7934	7-Methylcoumarin	Others	Others
	7-Methylcoumarin 具有很强的保肝活性。
T6S1435	Notopterol	Apoptosis; Others	Apoptosis; Others
	Notopterol 是从羌活提取的一种香豆素，可诱导细胞凋亡，具有解热、缓解疼痛和抗炎作用。它有用于急性髓细胞性白血病的潜力。
TN5888	Toddaculin	Others	Others
	Toddaculin 是一种天然香豆素，抑制过度的破骨细胞活性并增强成骨细胞分化和矿化。它可诱导白血病细胞分化和凋亡，具有抗炎活性。
T8002	3-Hydroxycoumarin	Lipoxygenase	Metabolism
	3-hydroxycoumarin 是一种 15-LOX-1的有效氧化还原抑制剂，近期被证明能保护海胆生殖细胞免受紫外线 B 的损伤。
T8038	7-Ethoxy-4-Methylcoumarin	Others	Others
	7-Ethoxy-4-Methylcoumarin 具有独特气味的芳香化合物。它被认为是细胞中酶的抑制剂，已被用于酶抑制的研究，并已被用于研究各种药物对人体的影响。
T3872	Nodakenin 紫花前胡苷,(+)-Marmesinin	AChE	Neuroscience
	Nodakenin ((+)-Marmesinin) 是一种Peucedanum decursivum Maxim 根中的主要香豆素苷。它能够抑制乙酰胆碱酯酶活性，IC50=84.7 μM。
T3888	Scopolin Murrayin,东莨菪甙,Scopoloside,东莨菪苷	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Scopolin (Scopoloside) 是从拟南芥根中分离出来的香豆素，可通过激活SIRT1介导的信号级联反应减轻了肝脂肪变性。
T4S0592	Toddalolactone (+)-Toddalolactone,飞龙掌血内酯,毛两面针素	PAI-1	Metabolism
	Toddalolactone ((+)-Toddalolactone) 是一种Toddalia asiatica 的主要成分，能够抑制重组人纤溶酶原激活物抑制物-1(PAI-1)的活性， IC50=37.31 μM。
TN1328	7-Amino-4-methylcoumarin-3-acetic acid 7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin	Others	Others
	7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) 是荧光蛋白质标记剂，能够被紫外光(350 nm) 激活，可在蓝色区域 (440-460 nm) 发光。
TJS0328	Nordalbergin 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素	Others	Others
	Nordalbergin 是一种香豆素，分离自Dalbergia sissoo的木皮中。它能够显著性的诱导 HL-60 细胞的分化。
TJS0312	7-hydroxy-4-methyl-8-nitrocoumarin	Others	Others
	7-Hydroxy-4-methyl-8-nitrocoumarin 是香豆素衍生物的一种。
T5647	6-Methylcoumarin Toncarine,6-甲基香豆素	Others	Others
	6-Methylcoumarin (Toncarine) 是一种合成香料，广泛用于化妆品中。
PDK0015	4-Hydroxycoumarin	Endogenous Metabolite; Antibacterial; AChR	Metabolism; Microbiology/Virology; Neuroscience
	4-Hydroxycoumarin 是香豆素衍生物，也是通用的杂环支架之一，具有亲电和亲核性质。
TJS0318	6-Hydroxy-4-methylcoumarin 6-羟基-4-甲基香豆素,6-Hydroxy-4-Methyl-2H-Chromen-2-One,6-羟基-4-甲基香豆素；6-羟基-4-甲基-2H-1-苯并吡喃-2-酮	Others	Others
	6-Hydroxy-4-methylcoumarin (6-Hydroxy-4-Methyl-2H-Chromen-2-One) 是一种香豆素的次级代谢产物，具有抗癌作用。
Fr12277	4-Hydroxy-6-methylcoumarin	Others	Others
	4-Hydroxy-6-methylcoumarin（4-HMC）是一种天然存在的酚类化合物，是香豆素的衍生物，存在于各种植物、真菌和细菌中，具有抗炎和抗肿瘤活性。4-HMC 在食品工业中用作调味剂、防腐剂和抗氧化剂。
T4137	4,7-DIHYDROXYCOUMARIN	Others	Others
	4,7-DIHYDROXYCOUMARIN 是一种天然存在的香豆素衍生物，存在于多种植物中，包括欧芹和洋甘菊。已经发现它可以抑制几种酶的活性，包括细胞色素P450、环氧合酶和脂氧合酶；也可以与DNA 结合，调节基因表达，并抑制细胞周期进展；还可以诱导肿瘤细胞凋亡并减轻炎症。
TN1552	7,8-Dimethoxycoumarin 7,8-dimethoxychromen-2-one,Daphnetin dimethyl ether	Others	Others
	7,8-Dimethoxycoumarin 是一种从 Artemisia caruifolia 和 Wikstroemia indica 中分离出来的天然产物。
T2S0357	6-Hydroxycoumarin 6-hydroxychromen-2-one,6-羟基香豆素	Others; Carbonic Anhydrase	Metabolism; Others
	6-Hydroxycoumarin (6-hydroxychromen-2-one) 是一种香豆素。其中香豆素具有抗炎，支气管扩张，解热，血管扩张，抗氧化，抗菌，抗真菌，抑菌和抗肿瘤作用。
T7993	8-Acetyl-7-Hydroxycoumarin	Antifungal	Microbiology/Virology
	8-Acetyl-7-Hydroxycoumarin 是一种天然化合物，具有抗真菌和抗菌活性。
T5744	7-Prenyloxycoumarin 7-(异戊烯基氧基)香豆素,Nsc267697,7-O-Prenylumbelliferone,7-异戊烯氧基香豆素	Antifungal	Microbiology/Virology
	7-Prenyloxycoumarin (Nsc267697) 是一种 Heracleum dissectum 的天然产物，对乳腺癌具有预防和治疗作用。
TN1702	Glycycoumarin 甘草香豆素	P450; JNK; AMPK; Autophagy	Autophagy; Chromatin/Epigenetic; MAPK; Metabolism; PI3K/Akt/mTOR signaling
	Glycycoumarin 是甘草中的一种香豆素，能直接靶向 T-LAK 细胞源蛋白激酶发挥抗肝癌活性。它通过激活自噬，抑制内质网应激介导的 JNK 和 GSK-3 介导的线粒体途径，来抑制肝细胞脂性凋亡。它是一种雌激素激动剂，对 CYP1A2 和 CYP2B6 有中度抑制作用。
Fr12596	3-Acetylcoumarin	Others	Others
	3-Acetylcoumarin 作为室温下铜催化 CN 偶联反应的实用配体。它具有神经保护和杀螨特性。
Fr12290	4-Methoxycoumarine	Others	Others
	4-Methoxycoumarine 具有抗肿瘤作用。
TJS0314	5,7-Dihydroxy-4-methylcoumarin Methyl-2H-Chromen-2-One,5,7-二羟基-4-甲基香豆素,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin	Others; Antibacterial; Antifungal	Microbiology/Virology; Others
	5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) 是墨西哥龙蒿中的一种香豆素衍生物。它抑制人类中性粒细胞氧化代谢和弹性蛋白酶活性，有抗真菌和抗细菌活性。
Fr12662	4-Ethoxycoumarin	Others	Others
	4-Ethoxycoumarin 具有抗菌活性。
T7970	7-Ethoxycoumarin	Others	Others
	7-Ethoxycoumarin 是细胞色素 P450(CYP) 的底物，现已被应用于多种 CYP 的功能表征。
T2S0300	Dihydrocoumarin 二氢香豆素,Chroman-2-one,Hydrocoumarin,melilotin,2-chromanone,3,4-dihydrocoumarin,二氢香豆素；氢化肉桂酸内酯、1,2-苯并二氢吡喃酮、二氢色满酮、二羟基香豆素;苯并二氢吡喃酮;二氢香豆酯、二氢香兰素	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Dihydrocoumarin (melilotin) 是在草木犀中发现的一种天然产物。它是酵母 Sir2p 抑制剂，还抑制人 SIRT1和SIRT2，IC50分别为 208 和 295 μM。
T8113	4-Methyl-6-Methoxycoumarin	Others	Others
	4-Methyl-6-Methoxycoumarin 是一种从 Eupatorium pauciflorum 中分离出来的天然产物。
TN3110	5-Geranoxy-7-methoxycoumarin	Anti-infection; Antibacterial; Antifungal	Microbiology/Virology
	5-Geranoxy-7-methoxycoumarin 是一种香豆素。它诱导细胞凋亡，具有抗癌、抗真菌和抗菌活性。
TJP2865	7-methoxy-8-hydroxy-4-methylcoumarin	Others	Others
	7-methoxy-8-hydroxy-4-methylcoumarin 是分离自酸橙 (Citrus aurantium) 的一种化合物。
TJS0368	4-Phenyl-7,8-dihydroxycoumarin 7,8-二羟基-4-苯基香豆素,7,8-Dihydroxy-4-Phenyl-2H-Chromen-2-One,7,8-Dihydroxy-4-phenylcoumarin	Others	Others
	4-Phenyl-7,8-dihydroxycoumarin (7,8-Dihydroxy-4-phenylcoumarin) 是香豆素衍生物，可用于研究支气管扩张。
T81334	Qianhucoumarin B
	Qianhucoumarin B, 香豆素类衍生物，源自中药Peucedanum praeruptorum根部提取。
T81333	Qianhucoumarin C
	Qianhucoumarin C是从白前胡(Peucedanum praeruptorum)根部提取的香豆素类化合物，已研究其具有抗炎、抗氧化和抗癌等潜在药用活性。Qianhucoumarin C亦在多个工业流程中发挥重要作用，尤其是在制药和草药制造过程中。
TN4880	Qianhucoumarin A	Others	Others
	Qianhucoumarin A是一种天然产物，属于伞形科前胡属，其产品编号为 TN4880，CAS号为 150135-35-6。Qianhucoumarin A可用作对照参考。
TN3271	8-Acetyl-7-methoxycoumarin	Others	Others
	8-Acetyl-7-methoxycoumarin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3271，CAS号为 89019-07-8。
T11683	Isoglycycoumarin	Others	Others
	Isoglycycoumarin, a flavonoid derived from the roots of Glycyrrhiza uralensis, serves as a highly selective probe for human cytochrome P450 2A6.
TN3225	7-Geranyloxy-5-methoxycoumarin	Others	Others
	7-Geranyloxy-5-methoxycoumarin 是一种天然存在的化合物，存在于许多植物中，包括红枫树的树皮。它已被证明具有抗炎、抗氧化和抗肿瘤的特性。
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天然产物

Cat.No: T0775

Target: Factor Xa, Influenza Virus

Cat.No: TN1529

Synonym: Coumarin VI,香豆素 6

Target: Others

7-Amino-4-(trifluoromethyl)coumarin

Cat.No: TJS0341

Synonym: 香豆素151,Coumarin 151,AFC,7-氨基-4-（三氟甲基）香豆素

Target: 5-HT Receptor

Cat.No: T7960

Synonym: 香豆素-7,香豆素7

Target: Others

Coumarin-3-carboxylic acid

Cat.No: TJS0339

Synonym: 香豆素-3-羧酸,3-Carboxycoumarin

Target: VEGFR

Cat.No: T2909

Synonym: 7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀

Target: Apoptosis, Others

3-Aminocoumarin

Cat.No: TN1243

Synonym: 3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine

Target: Others

7-(3'-Carboxybutoxy)coumarin

Cat.No: TN6209

Ethyl 3-coumarincarboxylate

Cat.No: TJS0311

Synonym: 3-Ethoxycarbonylcoumarin,香豆素-3-羧酸乙酯,香豆素-3-羧酸乙素,Ethyl 2-Oxo-2H-Chromene-3-Carboxylate,Ethyl coumarin-3-carboxylate,3-Carbethoxycoumarin

Target: Others

Cat.No: TN2024

Target: Others

7-(6'R-hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin

Cat.No: TN6207

5,7-Dihydroxycoumarin

Cat.No: T37345

Target: Antibacterial

Cat.No: TN1120

Target: MAO, Monoamine Oxidase

7-Methylcoumarin

Cat.No: T7934

Target: Others

Cat.No: T6S1435

Target: Apoptosis, Others

Cat.No: TN5888

Target: Others

3-Hydroxycoumarin

Cat.No: T8002

Target: Lipoxygenase

7-Ethoxy-4-Methylcoumarin

Cat.No: T8038

Target: Others

Cat.No: T3872

Synonym: 紫花前胡苷,(+)-Marmesinin

Target: AChE

Cat.No: T3888

Synonym: Murrayin,东莨菪甙,Scopoloside,东莨菪苷

Target: Sirtuin

Cat.No: T4S0592

Synonym: (+)-Toddalolactone,飞龙掌血内酯,毛两面针素

Target: PAI-1

7-Amino-4-methylcoumarin-3-acetic acid

Cat.No: TN1328

Synonym: 7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin

Target: Others

Cat.No: TJS0328

Synonym: 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素

Target: Others

7-hydroxy-4-methyl-8-nitrocoumarin

Cat.No: TJS0312

Target: Others

6-Methylcoumarin

Cat.No: T5647

Synonym: Toncarine,6-甲基香豆素

Target: Others

4-Hydroxycoumarin

Cat.No: PDK0015

Target: Endogenous Metabolite, Antibacterial, AChR

6-Hydroxy-4-methylcoumarin

Cat.No: TJS0318

Synonym: 6-羟基-4-甲基香豆素,6-Hydroxy-4-Methyl-2H-Chromen-2-One,6-羟基-4-甲基香豆素；6-羟基-4-甲基-2H-1-苯并吡喃-2-酮

Target: Others

4-Hydroxy-6-methylcoumarin

Cat.No: Fr12277

Target: Others

4,7-DIHYDROXYCOUMARIN

Cat.No: T4137

Target: Others

7,8-Dimethoxycoumarin

Cat.No: TN1552

Synonym: 7,8-dimethoxychromen-2-one,Daphnetin dimethyl ether

Target: Others

6-Hydroxycoumarin

Cat.No: T2S0357

Synonym: 6-hydroxychromen-2-one,6-羟基香豆素

Target: Others, Carbonic Anhydrase

8-Acetyl-7-Hydroxycoumarin

Cat.No: T7993

Target: Antifungal

7-Prenyloxycoumarin

Cat.No: T5744

Synonym: 7-(异戊烯基氧基)香豆素,Nsc267697,7-O-Prenylumbelliferone,7-异戊烯氧基香豆素

Target: Antifungal

Cat.No: TN1702

Synonym: 甘草香豆素

Target: P450, JNK, AMPK, Autophagy

3-Acetylcoumarin

Cat.No: Fr12596

Target: Others

4-Methoxycoumarine

Cat.No: Fr12290

Target: Others

5,7-Dihydroxy-4-methylcoumarin

Cat.No: TJS0314

Synonym: Methyl-2H-Chromen-2-One,5,7-二羟基-4-甲基香豆素,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin

Target: Others, Antibacterial, Antifungal

4-Ethoxycoumarin

Cat.No: Fr12662

Target: Others

7-Ethoxycoumarin

Cat.No: T7970

Target: Others

Dihydrocoumarin

Cat.No: T2S0300

Synonym: 二氢香豆素,Chroman-2-one,Hydrocoumarin,melilotin,2-chromanone,3,4-dihydrocoumarin,二氢香豆素；氢化肉桂酸内酯、1,2-苯并二氢吡喃酮、二氢色满酮、二羟基香豆素;苯并二氢吡喃酮;二氢香豆酯、二氢香兰素

Target: Sirtuin

4-Methyl-6-Methoxycoumarin

Cat.No: T8113

Target: Others

5-Geranoxy-7-methoxycoumarin

Cat.No: TN3110

Target: Anti-infection, Antibacterial, Antifungal

7-methoxy-8-hydroxy-4-methylcoumarin

Cat.No: TJP2865

Target: Others

4-Phenyl-7,8-dihydroxycoumarin

Cat.No: TJS0368

Synonym: 7,8-二羟基-4-苯基香豆素,7,8-Dihydroxy-4-Phenyl-2H-Chromen-2-One,7,8-Dihydroxy-4-phenylcoumarin

Target: Others

Qianhucoumarin B

Cat.No: T81334

Qianhucoumarin C

Cat.No: T81333

Qianhucoumarin A

Cat.No: TN4880

Target: Others

8-Acetyl-7-methoxycoumarin

Cat.No: TN3271

Target: Others

Isoglycycoumarin

Cat.No: T11683

Target: Others

7-Geranyloxy-5-methoxycoumarin

Cat.No: TN3225

Target: Others

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01184	CYP2A6 Protein, Human, Recombinant (His & Myc) CYP2A3,Coumarin 7-hydroxylase,1,4-cineole 2-exo-mon...	Human	E. coli
	CYP2A6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

重组蛋白

CYP2A6 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01184

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0371	Coumarin-d4
	Coumarin-d4 是 Coumarin 的氘代化合物。Coumarin 的 CAS 号为 91-64-5。Coumarin 是中国北沙参中的一种主要生物活性成分，具有抗癌、抗炎和抗病毒等活性。它作为几种抗凝剂的前体具有临床价值，尤其是华法林。

同位素标记化合物

Cat.No: TMIJ-0371

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