Cat. No. | Product Name | Target | Signaling Pathways |
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T35663 |
Cortistatin-29 (rat) (trifluoroacetate salt)
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Others | Others |
Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Cortistatin mRNA is expressed in the human brain and in interneurons of the rat hippocampus and cerebral cortex. Cortistatin-29 binds to somatostatin (SST) receptors with IC50 values of 2.8, 7.1, 0.2, 3, and 13.7 nM for SST1-... | |||
T35662 |
Cortistatin-29 (1-13) (rat) (trifluoroacetate salt)
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Others | Others |
Cortistatin-29 (1-13) is a neuropeptide and cleavage product of cortistatin-29 , which is a cleavage product of procortistatin. Cortistatin-29 (1-13) corresponds to the first 13 amino acids of cortistatin-29. | |||
T76331 |
Cortistatin 29
|
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Cortistatin 29,一种具备高亲和力结合至所有生长抑素(SS)受体亚型的神经肽,其对SSTR1、SSTR2、SSTR3、SSTR4、SSTR5的IC50值分别为2.8, 7.1, 0.2, 3.0, 13.7 nM。该化合物不仅能减轻神经性疼痛,还表现出抗纤维化作用。 |