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Search Results for " connexin-43 "

Targets Recommended: Gap Junction Protein

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T5192	Gap 26	Gap Junction Protein	Cytoskeletal Signaling
	Gap 26 是模拟肽，对应于连接蛋白 43 的残基 63-75，是间隙连接阻断剂。
TP1333	Gap 27	Gap Junction Protein	Cytoskeletal Signaling
	Gap 27是一种合成的 connexin43 模拟肽，是一种间隙连接抑制剂。它与通往第二跨膜连接蛋白区段的第二细胞外环的一部分具有保守的序列同源性。
T75795	Gap 26 TFA
	Gap 26 TFA 是一种连接蛋白 (connexin) 模拟肽，由连接蛋白 connexin 43 (gap junction 阻滞剂)一个胞外环的第 63-75 残基组成，包含SHVR 氨基酸基序。
TP1511	Gap19 TFA (1507930-57-5 free base) Gap19 TFA
	Gap19 TFA is a peptide derived from nine amino acids of Cx43 cytoplasmic ring (CL), an effective, selective connexin 43 (Cx43) half-channel blocker.
T78061	Peptide5 TFA	Gap Junction Protein	Cytoskeletal Signaling
	Peptide5 TFA，一种connexin 43模拟肽，能够降低动物脊髓损伤后的肿胀、抑制星形胶质细胞增生和神经元死亡。该化合物还可抑制NLRP3炎症小体，具有抗炎作用。
T75820	Gap19 TFA
	Gap19 TFA，源自Cx43胞浆环(CL)的九个氨基酸肽，是高效且选择性的连接蛋白43 (Cx43) 半通道阻滞剂。该肽阻止C末端（CT）与CL之间的分子内相互作用，但不影响GJ通道或Cx40/pannexin-1半通道。此外，Gap19 TFA对心肌有保护作用。
T36851	Peptide5
	Connexin43 mimetic peptide. Reduces swelling, astrogliosis, neuroinflammation and neuronal cell death following spinal cord injury ex vivo and in vivo. Exhibits analgesic effects in models of neuropathic pain. O'Carroll et al (2008) Connexin 43 mimetic peptides reduce swelling, astrogliosis and neuronal cell death after spinal cord injury. Cell.Commun.Adhes. 15 27 PMID:18649176 \|Mao et al (2017) Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats....

化合物

Gap 26

Cat.No: T5192

Synonym:

Target: Gap Junction Protein

Gap 27

Cat.No: TP1333

Synonym:

Target: Gap Junction Protein

Gap19 TFA (1507930-57-5 free base)

Cat.No: TP1511

Synonym: Gap19 TFA

Target: Gap Junction Protein

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01372	GJA1 Protein, Human, Recombinant (His) Gap junction 43 kDa heart protein,GJA1,Connexin...	Human	E. coli
	GJA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.3 kDa and the accession number is P17302.
TMPH-02669	GJA1 Protein, Mouse, Recombinant (His & Myc) Gap junction 43 kDa heart protein,Gja1,Gap junction...	Mouse	Baculovirus Insect Cells
	Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibi...