|
TMPY-00653
|
Complement C5 Protein, Human, Recombinant (Complement C5a)
C5D,C5b,CPAMD4,complement component 5,Complemen...
|
Human
|
E. coli
|
|
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is P01031. |
|
TMPH-02597
|
C1QA Protein, Mouse, Recombinant (His)
Complement C1q subcomponent subunit A,C1QA
|
Mouse
|
P. pastoris (Yeast)
|
|
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
|
TMPK-00776
|
Complement factor I Protein, Human, Recombinant (His)
FIC3b-INA,KAF,IF,CFI,I factor (complement),EC:3.4.2...
|
Human
|
HEK293 Cells
|
|
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64.58 kDa and the accession number is P05156. |
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TMPK-01023
|
Complement factor I Protein, Mouse, Recombinant (His)
FIC3b-INA,I factor (complement),IF,C3B/C4B inactiva...
|
Mouse
|
HEK293 Cells
|
|
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 66.39 kDa and the accession number is Q61129. |
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TMPJ-00417
|
Complement C3a Protein, Human, Recombinant
Anaphylatoxin,C3a,Complement Component C3a
|
Human
|
E. coli
|
|
Complement C3a Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 KDa and the accession number is P01024. |
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TMPJ-00416
|
Complement C3a Protein, Mouse, Recombinant
C3a,Complement Component C3a,Anaphylatoxin
|
Mouse
|
E. coli
|
|
Complement C3a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 KDa and the accession number is P01027. |
|
TMPH-02921
|
SUSD4 Protein, Mouse, Recombinant (His)
Sushi domain-containing protein 4,Susd4
|
Mouse
|
E. coli
|
|
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways. SUSD4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.5 kDa and the accession number is Q8BH32. |
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TMPY-04902
|
Complement C5a Protein, Mouse, Recombinant
complement component 5
|
Mouse
|
E. coli
|
|
Complement C5a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. |
|
TMPH-00231
|
Complement C3 Protein, Bovine, Recombinant (His & SUMO)
Complement C3,C3
|
Bovine
|
E. coli
|
|
Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.5 kDa and the accession number is Q2UVX4. |
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TMPY-05459
|
Complement C5a Protein, Mouse, Recombinant, Biotinylated
complement component 5
|
Mouse
|
E. coli
|
|
Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. |
|
TMPH-03270
|
Complement C5 Protein, Rat, Recombinant (His & Myc)
Complement C5,C5
|
Rat
|
E. coli
|
|
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.0 kDa and the accession number is P08650. |
|
TMPH-03574
|
SdrE Protein, S. aureus, Recombinant (His)
sdrE,Serine-aspartate repeat-containing protein E
|
Staphylococcus aureus
|
E. coli
|
|
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clearance by interacting with host complement factor H/CFAH and modulating its activity. Inhibits also bacterial opsonization and killing by interacting with host complement regulator C4BPA and thus inhibiting classical complement pathway activation. SdrE Protein, S. aureus, Recombin... |
|
TMPH-02607
|
Complement factor B Protein, Mouse, Recombinant (His)
C3/C5 convertase,Complement factor B,Cfb,Bf,H2-Bf
|
Mouse
|
E. coli
|
|
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. |
|
TMPH-02602
|
C1RA Protein, Mouse, Recombinant (His & Myc)
Complement component 1 subcomponent r-A,C1ra,C1r,
|
Mouse
|
E. coli
|
|
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. |
|
TMPJ-00809
|
CFH Protein, Human, Recombinant (His)
CFH,Complement factor H
|
Human
|
HEK293 Cells
|
|
Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessi... |
|
TMPH-02604
|
Complement C3 Protein, Mouse, Recombinant (His & SUMO)
C3,Complement C3
|
Mouse
|
E. coli
|
|
Complement C3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.3 kDa and the accession number is P01027. |
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TMPY-02023
|
CD46 Protein, Human, Recombinant (His)
AHUS2,MIC10,CD46 molecule, complement regulatory pr...
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Human
|
HEK293 Cells
|
|
CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic... |
|
TMPJ-01064
|
Serpin G1 Protein, Mouse, Recombinant (His)
Serping1,Plasma protease C1 inhibitor,C1 Inh,C1 esterase inh...
|
Mouse
|
HEK293 Cells
|
|
SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation. SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. SERPIN G1 prevents the proteolytic cleavage of later... |
|
TMPH-02376
|
OmpC Protein, Klebsiella pneumoniae, Recombinant (His & Myc)
Outer membrane porin C,ompC,Porin OmpC,Porin ompk36,Outer me...
|
Klebsiella pneumoniae
|
E. coli
|
|
Forms pores that allow passive diffusion of small molecules across the outer membrane. In K.pneumoniae it has been shown to bind the C1Q component and activate the classical pathway of the complement system. OmpC Protein, Klebsiella pneumoniae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 45.0 kDa and the accession number is Q48473. |
|
TMPH-02603
|
C1SB Protein, Mouse, Recombinant (His & Myc)
C1sb,C1s,Gm5077,Complement C1s-1 subcomponent,C...
|
Mouse
|
E. coli
|
|
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. |
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TMPH-02606
|
CR1L Protein, Mouse, Recombinant (His)
Crry,Complement regulatory protein Crry,Complem...
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Mouse
|
E. coli
|
|
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. CR1L Prot... |
|
TMPY-06585
|
C1s Protein, Human, Recombinant (His)
complement component 1, s subcomponent,C1s,FLJ44757
|
Human
|
HEK293 Cells
|
|
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex composed of the binding protein C1q and two proenzymes, C1r and C1s. Upon binding of IgG to the head of C1q, C1r undergoes autoactivation and in turn cleaves and activates C1s. C1r and C1s, the proteases responsible for activation and proteolytic activity of the C1 complex of complem... |
|
TMPH-03762
|
TPP2 Protein, Mouse, Recombinant (E. coli, His & Myc)
Tpp2,Tripeptidyl-peptidase 2,Tripeptidyl aminopeptidase,Trip...
|
Mouse
|
E. coli
|
|
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis. TPP2 Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.5 kDa and the accession number is Q64514. |
|
TMPH-03559
|
Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated
sbi,Immunoglobulin-binding protein Sbi
|
Staphylococcus aureus
|
E. coli
|
|
Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis. Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The... |
|
TMPH-01447
|
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein C (His)
gC,Envelope glycoprotein C
|
HHV-2
|
E. coli
|
|
Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Plays also a role in host immune evasion by inhibiting the host complement cascade activation. Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein C (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 50.5 kDa and the accession number is Q89730. |
|
TMPH-02596
|
C1QA Protein, Mouse, Recombinant (E. coli, His)
C1QA,Complement C1q subcomponent subunit A
|
Mouse
|
E. coli
|
|
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
|
TMPH-01339
|
Ficolin 3/FCN3 Protein, Human, Recombinant (His)
Collagen/fibrinogen domain-containing protein 3,Hakata antig...
|
Human
|
E. coli
|
|
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota. Ficolin 3/FCN3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.4 kDa and the accession number is O75636. |
|
TMPH-01134
|
Complement C8g Protein, Human, Recombinant (His)
C8G,Complement component C8 gamma chain
|
Human
|
E. coli
|
|
C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Complement C8g Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P07360. |
|
TMPH-03327
|
MBL2 Protein, Rat, Recombinant (His)
Mannan-binding protein,Ra-reactive factor polysaccharide-bin...
|
Rat
|
E. coli
|
|
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession num... |
|
TMPH-01133
|
Complement C8b Protein, Human, Recombinant (His)
Complement component C8 beta chain,C8B,Compleme...
|
Human
|
E. coli
|
|
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Complement C8b Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 67.0 kDa and the accession number is P07358. |
|
TMPH-03166
|
Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
PAE,lasB,Pseudolysin,Neutral metalloproteinase,Elastase
|
Pseudomonas aeruginosa
|
E. coli
|
|
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD). Involved in the pathogenesis of P.aeruginosa infections. Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.1 kDa and the accession number is P14756. |
|
TMPH-03326
|
MASP2 Protein, Rat, Recombinant (His)
Mannan-binding lectin serine protease 2,MBL-associated serin...
|
Rat
|
Baculovirus Insect Cells
|
|
Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. MASP2 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 79.2 kDa and the accession number is Q9JJS8. |
|
TMPJ-00502
|
Serpin G1 Protein, Human, Recombinant (His)
C1-Inhibiting Factor,Serpin G1,SERPING1,C1 Esterase Inhibito...
|
Human
|
HEK293 Cells
|
|
As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein. It is the largest member among the serpin class of proteins. Remarkably, Serpin G1 has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of Serpin G1 provides the inhibitory activity. The N-terminal domain ... |
|
TMPK-01194
|
IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-22,Cytokine Zcyto18,白细胞介素,IL-TIF,白介素,Interleukin-22,TIFIL...
|
Mouse
|
E. coli
|
|
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 19.7 kDa and the accession number i... |
|
TMPH-03757
|
TPP2 Protein, Human, Recombinant (E. coli, His & Myc)
TPP2,Tripeptidyl-peptidase II,Tripeptidyl-peptidase 2,Tripep...
|
Human
|
E. coli
|
|
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis. TPP2 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.8 kDa and the accession number is P29144. |
|
TMPH-03665
|
Vaccinia virus (strain Copenhagen) OPG185 Protein (His)
Hemagglutinin,Protein OPG185,OPG185
|
VACV
|
E. coli
|
|
Prevents cell to cell fusion by interacting with and directing the viral K2 protein on the host plasma membrane. The A56-K2 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation. Via its interaction with C3/VCP protein, protects the infected cell and probably also the extracellular enveloped virus from complement attack. Vaccinia virus (strain Copenhagen) OPG185 Protein (His) is expressed in E. coli expression system with ... |
|
TMPY-01712
|
C1QB Protein, Human, Recombinant (His)
complement component 1, q subcomponent, B chain,C1Q...
|
Human
|
Baculovirus Insect Cells
|
|
Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Southern blot analysis of chromosomal DNA from vertebrate species demonstrated highest similarity between the C1qB genes, followed by C1qC and finally C1qA. Sequence comparison of C1... |
|
TMPH-03528
|
Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc)
chp,Chemotaxis inhibitory protein,CHIPS
|
Staphylococcus aureus
|
E. coli
|
|
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS... |
|
TMPH-03578
|
SCIN Protein, S. aureus, Recombinant (His & Myc)
scn,Staphylococcal complement inhibitor
|
Staphylococcus aureus
|
E. coli
|
|
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses. SCIN Protein, S. aureus, ... |
|
TMPY-01733
|
SIGNR1 Protein, Mouse, Recombinant (His)
CD209b antigen,DC-SIGNR1,OtB7,SIGNR1,1810030I22Rik,mSIGNR1
|
Mouse
|
HEK293 Cells
|
|
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... |
|
TMPY-01692
|
NETO1 Protein, Human, Recombinant (His)
neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTCL1
|
Human
|
HEK293 Cells
|
|
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr... |
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