Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T84380 |
5'-Ethynyl-2'-deoxycytidine
EdC,2'-deoxy-5-Ethynylcytidine,Click Tag™ 5'-Ethynyl-2'-deoxycytidine |
Others | Others |
5'-Ethynyl-2'-deoxycytidine (EdC) functions as a nucleoside analog effectively inhibiting the replication of herpes simplex virus-1 (HSV-1) KOS strain with an ID50 of 0.2 μg/mL. Additionally, it decreases virus-induced cytopathogenic effects in PRK cells for HSV-1, HSV-2, and vaccinia virus strains, demonstrating MIC values between 0.2 to 5 μg/mL. EdC acts as a thymidylate synthetase inhibitor, selectively impacting the DNA incorporation rates of [1',2'-3H]deoxyuridine compared to [CH3-3H]deoxyt... |