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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T69207 |
Chelerythrine hydroxide
|
Others | Others |
Chelerythrine hydroxide is the salt form of Chelerythrine, a benzophenanthridine alkaloid present in the plant Chelidonium majus (greater celandine). It is a potent, selective, and cell-permeable protein kinase C inhibitor in vitro. And an efficacious antagonist of G-protein-coupled CB1 receptors.]This molecule also exhibits anticancer qualities and it has served as a base for many potential novel drugs against cancer. | |||
T126454 |
6-Methoxyldihydrochelerythrine chloride
|
Others | Others |
6-Methoxyldihydrochelerythrine chloride 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126454。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6S0052 |
Chelerythrine
Toddalin,Broussonpapyrine,白屈菜红碱,Cheleritrine |
Apoptosis; BCL; PKC; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling |
Chelerythrine (Broussonpapyrine) 是一种天然生物碱,为有效、选择性的 Ca2+/磷脂依赖性PKC 拮抗剂,IC50值为 0.7 μM。它具有抗肿瘤、抗糖尿病、抗炎的活性。它抑制BclXL-Bak BH3肽结合,IC50为 1.5 μM,并从 BclXL 取代了 Bax。它诱导细胞凋亡和自噬。 | |||
T3419 |
Chelerythrine chloride
白屈菜红碱,盐酸白屈菜红碱 |
Apoptosis; BCL; PKC; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling |
Chelerythrine chloride 是一种可渗透细胞的蛋白激酶 C 抑制剂,对磷酸盐受体具有竞争性,而对 ATP 是非竞争性的。它诱导细胞凋亡和自噬。 | |||
T3S0057 |
Dihydrochelerythrine
12,13-Dihydrochelerythrine,二氢白屈菜红碱 |
Antifungal | Microbiology/Virology |
Dihydrochelerythrine (12,13-Dihydrochelerythrine) 是一种从榕树叶片分离出的天然化合物,具有抗真菌活性,有潜力治疗多丝蚴引起的严重感染。 | |||
TN3152 |
6-Acetonyldihydrochelerythrine
|
ERK; BCL; Akt; HIV Protease; PPAR; p53 | Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively. 6-Acetonyldihydrochelerythrine is | |||
TN4725 |
Oxychelerythrine
|
Antifection | Microbiology/Virology |
Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeeding activities against Tribolium castaneum adults, with the EC50 of 192.32 p | |||
T2S0058 |
6-Ethoxychelerythrine
乙氧基白屈菜红碱,Ethoxychelerythrin |
Antibacterial | Microbiology/Virology |
6-Ethoxychelerythrine (Ethoxychelerythrin) 具有抗菌活性,对烟曲霉和耐甲氧西林金黄色葡萄球菌 (MRSA) 表现出很强的活性。 | |||
TN1991 |
Norchelerythrine
|
Antifection | Microbiology/Virology |
Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activity in a concentration-dependant manner with the EC50 of 62.67 ppm. | |||
T83281 |
6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine
|
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6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine 显著影响细胞器特性,涉及早期内体、线粒体及自噬体(源自帕金森病患者的嗅觉细胞)。 |