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Search Results for " che "

Targets Recommended: AChE Others

235

抑制剂 & 化合物

135

天然产物

3

化合物库

17

重组蛋白

6

同位素标记化合物

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Cat. No.	Product Name
L5100	含氟化合物库		574 compounds
	574 个含氟化合物的独特集合，可用于高通量筛选和高内涵筛选；
L7600	趋化因子抑制剂库		59 compounds
	59 种趋化因子或其受体抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
L2151	化疗药物库		48 compounds
	48 个肿瘤化疗药物，可以用于高通量和高内涵筛选；

化合物库

含氟化合物库

Cat.No: L5100

Compounds: 574

趋化因子抑制剂库

Cat.No: L7600

Compounds: 59

化疗药物库

Cat.No: L2151

Compounds: 48

Cat. No.	Product Name	Target	Signaling Pathways
T60940	ChE/Aβ1-42-IN-1	Others	Others
	ChE/Aβ1-42-IN-1 (compound 28) 是一种有效的ChE 和Aβ1-42聚集抑制剂，具有良好的血脑屏障通透性。ChE/Aβ1-42-IN-1 对 AChE、BuChE 和 Aβ1-42聚集的IC50值分别为 0.062、0.767和1.227 μM。ChE/Aβ1-42-IN-1 是一种有效的多靶点抗阿尔茨海默病剂。
T19084	1-Naphthyl acetate	AChE	Neuroscience
	1-Naphthyl acetate 是一种有吸引力的生色底物，用于检测红细胞乙酰胆碱酯酶的活性。它具有检测有机磷农药中毒的潜力。
T14194	β-NETA α-NETA	AChE	Neuroscience
	β-NETA(α-NETA) 是胆碱乙酰转移酶(ChA；IC50=76 μM) 和胆碱酯酶 (ChE;IC50=40 µM)的非竞争性抑制剂，对乙酰胆碱酯的作用微弱 (AChE;IC50=1 mM)。
T9989	AChE-IN-27	Others	Others
	AChE-IN-27是一种用于高通量测定的小分子。
T7114	GALANTHAMINONE (-)-Narwedine,氢溴酸加兰他敏,Narwedin	AChE	Neuroscience
	Galanthaminone ((-)-Narwedine) 是一种竞争性的、可逆的胆碱酯酶抑制剂，可作用于多种记忆障碍疾病的研究。
T7891	Ipidacrine 伊匹达克林,NIK‐247	Others	Others
	Ipidacrine (NIK‐247) 是一种具有益智作用的化合物，也是一种胆碱酯酶抑制剂，具有药物活性，可用于阿尔茨海默病的治疗。
T21825	TAE-1	Beta Amyloid; AChE	Neuroscience
	TAE-1 是淀粉样蛋白-β 原纤维形成和聚集的抑制剂。它抑制胆碱酯酶 AChE 和 BuChE，IC50 分别为 0.3 μM 和 3.9 μM。
T1624	Neostigmine bromide Neoserine bromide,溴化新斯的明,Eustigmin bromide	AChE	Neuroscience
	Neostigmine Bromide 是一种胆碱酯酶抑制剂，不会穿过血脑屏障，可作用于重症肌无力。
T7640	Aldicarb sulfone 得灭克,丁醛肟威,涕灭威砜	AChE	Neuroscience
	Aldicarb sulfone 是一种氨基甲酸酯类杀虫剂，是一种胆碱酯酶抑制剂，能够抑制在突触乙酰胆碱的分解。
T0229	Rivastigmine SDZ-ENA 713,卡巴拉汀,S-Rivastigmine,Exelon,利凡斯的明	AChE	Neuroscience
	Rivastigmine (Exelon) 是具有口服活性的、有效的、可透过血脑屏障的胆碱酯酶抑制剂，可抑制丁酰胆碱酯酶和乙酰胆碱酯酶，IC50分别为 0.037 μM 和 4.15 μM。它是一种拟副交感神经剂或胆碱能剂，用于研究轻度至中度阿尔茨海默氏型痴呆和帕金森氏病引起的痴呆。
T1635	Fenchlorphos Ronnel,Dermafos,皮蝇磷	AChE; Parasite	Microbiology/Virology; Neuroscience
	Fenchlorphos (Dermafos) 是一种有机磷酸盐杀虫剂，是乙酰胆碱酯酶的抑制剂，能够引起线粒体功能障碍。
T20812	Azamethiphos 甲基吡啶磷,唑啶磷	AChE	Neuroscience
	Azamethiphos 是有机磷杀虫剂和神经毒性物质，能够抑制乙酰胆碱酯酶的活性。
T0713	Drofenine hydrochloride 盐酸六氢芬宁,Hexahydroadiphenine hydrochloride	AChE	Neuroscience
	Drofenine hydrochloride (Hexahydroadiphenine hydrochloride) 是竞争性胆碱酯酶抑制剂，ki=3 uM。
T1628	Rivastigmine tartrate SDZ-ENA 713,ENA 713,酒石酸卡巴拉汀	AChR; AChE	Neuroscience
	Rivastigmine tartrate (SDZ-ENA 713) 是一种具有口服活性的、可透过血脑屏障的胆碱酯酶抑制剂，能够抑制丁酰胆碱酯酶和乙酰胆碱酯酶。它是一种拟副交感神经剂或胆碱能剂，用于研究轻度至中度阿尔茨海默氏型痴呆和帕金森氏病引起的痴呆。
T0780	Pyridostigmine bromide 溴吡斯的明,Mestinon,溴化吡啶斯的明	AChE	Neuroscience
	Pyridostigmine bromide (Mestinon) 是一种可逆的胆碱酯酶抑制剂。
T7213	Demecarium bromide 地美溴铵,BC-48	AChE	Neuroscience
	Demecarium bromide (BC-48) 是一种有效的cholinesterase 抑制剂，Kiapp=0.15 μM，它可用研究于青光眼。
T2571	Benactyzine hydrochloride Neuroleptone,胃复康,盐酸贝那替嗪,Tranquilline,Amitakon	AChR; AChE	Neuroscience
	Benactyzine hydrochloride (Neuroleptone) 是丁酰胆碱酯酶抑制剂，其Ki=0.010 mM。
T21439	Tacrine 他克林,CS 12602,Tacrinum,Tetrahydroaminocrine	AChR	Neuroscience
	Tacrine (CS 12602) 一种间接胆碱能激动剂和中枢作用的抗胆碱酯酶。它被批准用于治疗阿尔茨海默病。
T7041	Donepezil E2020,Donepezilo,Aricept,多奈哌齐	AChE	Neuroscience
	Donepezil (Aricept) 是一种AChE 抑制剂，对牛 AChE 和人 AChE 的IC50分别为 8.12 nM 和 11.6 nM。
T4466	Pitofenone hydrochloride Baralgin Ketone Hydrochloride,Pitophenone hydrochloride,吡托非农盐酸盐	AChE	Neuroscience
	Pitofenone hydrochloride (Pitophenone hydrochloride) 是一种能够抑制乙酰胆碱酯酶活性的解痉化合物，对于来自牛红细胞和电鳗的乙酰胆碱酯酶的Ki 分别为 36 和 45 μM。
T22545	Acephate acetylphosphoramidothioicacido,s-dimethylester,Ortran,Orthene,Acetamidophos,chevronorthene,乙酰甲胺磷	AChE	Neuroscience
	Acephate (Orthene) 是能产生胆碱毒性的抗胆碱酯酶杀虫剂。它能够有效抑制蟑螂的 AChE，但对大鼠 AChE 的抑制作用较弱。
T2191	Tacrine hydrochloride (hydrate) Tacrine,他克林盐酸盐水合物,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine	AChR; AChE	Neuroscience
	Tacrine hydrochloride hydrate (Tetrahydroaminacrine) 是一种乙酰胆碱酯酶 (AChE) 和丁酰胆碱酯酶 (BChE) 的抑制剂，它们的IC50值分别为 31 nM 和 25.6 nM。
T1612	Neostigmine methyl sulfate Normastigmin,甲基硫酸新斯的明,甲硫酸新斯的明,Hodostin,Syntostigmin	AChR; AChE	Neuroscience
	Neostigmine methyl sulfate (Syntostigmin) 是一种乙酰胆碱酯酶的可逆抑制剂, 不能透过血脑屏障。
T2227	Hemicholinium 3 半胆碱基-3,Hemicholinium-3,Hemicholine	Others; AChE	Neuroscience; Others
	Hemicholinium 3 是一种竞争性的、高亲和力的胆碱转运蛋白 (HACU) 抑制剂，Ki=25 nM。它是一种神经肌肉阻滞剂，能够抑制乙酰胆碱 (ACh)的合成和释放。它抑制Epibatidine 诱发的收缩和 [3H] 乙酰胆碱释放，IC50分别为 897 nM 和 693 nM。
T1072	Loxeen Pridinol methanesulfonate,Α,Α-二苯基-1-哌啶丙醇(普立地诺甲磺酸盐 )	AChR	Neuroscience
	Loxeen (Pridinol methanesulfonate) 用作抗胆碱能药物和抗帕金森病药物。
T7465	4-Methylbenzylidene camphor Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC	AChE	Neuroscience
	4-Methylbenzylidene camphor 是有机的樟脑衍生物，应用于化妆品行业，具有保护皮肤抵抗紫外线（特别是紫外线B 辐射）的能力。
T6478	Donepezil Hydrochloride Aricept,BNAG,E2020,Donepezil HCl,盐酸多奈哌齐	AChR; AChE	Neuroscience
	Donepezil HCl(Aricept) 是可逆的选择性AChE 抑制剂，IC50=6.7 nM，对 AChE 的选择性高于 BuChE。Donepezil Hydrochloride (Aricept) 对 Aβ42 神经毒性具有神经保护作用。
T1552	Itopride hydrochloride 盐酸伊托必利,HSR803,盐酸依托必利,Ganaton	Dopamine Receptor; AChE	GPCR/G Protein; Neuroscience
	Itopride hydrochloride (Ganaton) 是一种促胃动力的 Benzamide 衍生物，是一种乙酰胆碱酯酶 (AChE) 和多巴胺受体 D2 (D2DR) 抑制剂。
T7002	Trihexyphenidyl hydrochloride Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride,盐酸苯海索	AChR	Neuroscience
	Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) 是一种抗毒蕈碱类的抗帕金森病药物，结合至M1毒蕈碱受体。
T1111	Pralidoxime Chloride 2-PAM chloride,吡啶醛肟甲氯,2-Pyridinealdoxime methochloride,2-PAM (chloride)	AChE	Neuroscience
	Pralidoxime Chloride (2-PAM chloride) 是一种肟类化合物，对中毒乙酰胆碱酯酶具有恢复作用，可用于有机磷中毒的研究。
T2319	Acotiamide monohydrochloride trihydrate Acotiamide hydrochloride,YM-443 HCl,盐酸阿考替胺,Z-338 HCl	AChE	Neuroscience
	Acotiamide monohydrochloride trihydrate (Z-338 HCl) 是一种首创的、具有口服活性的胃肠动力药。它通过促毒蕈碱受体拮抗作用和乙酰胆碱酯酶(AChE)抑制作用增强肠神经元释放的乙酰胆碱，从而增强胃排空和胃部适应性，有潜力用于功能性消化不良的研究。
T20539	Pirimiphos-methyl R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic	AChE; Parasite	Microbiology/Virology; Neuroscience
	Pirimiphos-methyl (AI3-27699) 是一种速效有机磷杀虫剂和杀螨剂，对目标生物的乙酰胆碱酯酶有抑制作用。甲基嘧啶磷常用于农粮贮藏过程中甲虫、鼻甲虫、飞蛾和蝽蛄的防治。
T0204	Protriptyline hydrochloride 盐酸普罗替林,Protriptyline HCl	5-HT Receptor; AChE	GPCR/G Protein; Neuroscience
	Protriptyline hydrochloride (Protriptyline HCl) 是一种含有一个仲胺的三环结构抗抑郁试剂，可以用于抑郁和 ADHD 的相关研究。它使动物精力充沛起激励作用，并且有时用于嗜睡症的相关研究。
T77758	AChE/BuChE-IN-4	AChE	Neuroscience
	AChE/BuChE-IN-4是一种具有口服活性和血脑屏障通透性的多靶点AChE/BuChE抑制剂，对AChE和BuChE的IC50值分别为2.08和7.41 μM。
T65070	Chenodeoxycholic Acid sodium salt CDCA sodium salt	FXR	Metabolism
	Chenodeoxycholic Acid sodium salt (CDCA sodium salt) 是一种人体中的胆汁酸，能够活化核受体 FXR，可挽救痉挛性截瘫 5 型和脑黄瘤病患者诱导多能干细胞衍生神经元的轴突变性，可用于研究胰腺坏死。
T60891	AChE/BChE/MAO-B-IN-1	MAO; AChE	Metabolism; Neuroscience
	AChE/BChE/MAO-B-IN-1是一种可逆的、非时间依赖且可透过血脑屏障的AChE、BChE 和MAO-B 抑制剂，对 hAChE、hBChE 和 hMAO-B 表现出抑制作用，IC50分别为 7.31、0.56 和 26.1 μM。AChE/BChE/MAO-B-IN-1具有神经保护作用且无明显细胞毒性。
T72066	CHET3	Potassium Channel	Membrane transporter/Ion channel
	CHET3 is a TASK-3 inhibitor that can be used to study pain.
T40335	AChE-IN-3	NO Synthase; AChE	Immunology/Inflammation; Neuroscience
	AChE-IN-3 对 AChE 有抑制作用，对 NO 抑制作用较强，其 EC50 为 0.57 μM。
T60092	CHEMBL1276927 N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide,N-[3-(1H-苯并[d]咪唑-2-基)苯基]-3-甲基苯甲酰胺	Antibacterial; Parasite	Microbiology/Virology
	CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) 对肺炎衣原体和多诺瓦尼利什曼原虫具有抗菌和抗寄生虫活性。
T14858	Calicheamicin Calicheamicin γ1,卡奇霉素	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Calicheamicin (Calicheamicin γ1) 是肿瘤抗生素，可引起DNA 双链断裂，抑制DNA 合成。
T80671	ACHE-IN-38 5,6-Dimethoxy-2-(piperidin-4-yl)methylene-indan-1-one	Antifungal	Microbiology/Virology
	ACHE-IN-38 是一种有效的Acetylcholinesterase 抑制剂，可用于合成具有抗炎、抗肿瘤和抗菌活性的化合物。
T60102L	Dimethylaminomicheliolide HCl	PKM	Metabolism
	Dimethylaminomicheliolide HCl 具有潜在的抗炎和抗肿瘤活性，通过靶向丙酮酸激酶 2 （PKM2）和重新连接有氧细胞群来抑制胶质母细胞瘤细胞的增殖。
T61969	AChE/BChE-IN-10	AChR; AChE	Neuroscience
	AChE/BChE-IN-10 (Compound 7b) 是有效的、血脑屏障渗透性的 AChE 和 BChE 双重抑制剂，IC50 值分别为 0.176 和 0.47 μM。AChE/BChE-IN-10 可以抑制 Aβ 的聚集。
T10630	BuChE-IN-TM-10 TM-10	AChR	Neuroscience
	BuChE-IN-TM-10 (TM-10) 是一种有效的丁基胆碱酯酶 (BuChE) 抑制剂，其IC50 值为8.9 nM。BuChE inhibitor 1能够抑制和分解自诱导的Aβ聚合, 表现出强大的抗氧化活性和良好的血脑屏障 (BBB) 渗透性。可用于阿尔兹海默症的研究。
T13639	Deferasirox (Fe3+ chelate)	Apoptosis	Apoptosis
	Deferasirox (Fe3+ chelate) 是一种可口服的铁螯合剂，具有潜在的抗癌活性，抑制 MCL-1 的抗凋亡活性，可用于研究铁超负荷。
T5884	Chelidamic acid 4-氧代-1,4-二氢-2,6-吡啶二甲酸,白屈氨酸	GluR	Neuroscience
	Chelidamic acid 是一种有效的谷氨酸脱羧酶抑制剂(Ki:33 μM)，也是含有吡喃骨架的杂环有机酸，与金属离子有良好的配位能力。
T77352	ACHE Inhibitor 12	Others	Others
	ACHE Inhibitor 12 对乙酰胆碱酯酶具有抑制作用，IC50值为0.38 µM。
T8598	CHEMBL241987 2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE	Adenosine Receptor	GPCR/G Protein; Neuroscience
	CHEMBL241987 靶向腺苷受体 A3（人）。
TP1617L	Chemerin-9 (149-157) acetate Chemerin-9 (149-157) acetate (676367-27-4 free base)	Others	Others
	Chemerin-9 (149-157) acetate (676367-27-4 free base) 对应于加工的 chemerin 的 C 末端，保留了全尺寸蛋白质的大部分活性和关于对 chemerinR 的激动。它是 ChemR23 (chemerinR) 的天然配体。
T60093	CHEMBL1380345 N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)	Antibacterial	Microbiology/Virology
	CHEMBL1380345 对金黄色葡萄球菌、蜡状芽孢杆菌和大肠杆菌具有抗菌活性，pMIC 值分别为 3.64、3.56 和 3.70。

化合物

ChE/Aβ1-42-IN-1

Cat.No: T60940

Target: Others

1-Naphthyl acetate

Cat.No: T19084

Target: AChE

Cat.No: T14194

Synonym: α-NETA

Target: AChE

Cat.No: T9989

Target: Others

Cat.No: T7114

Synonym: (-)-Narwedine,氢溴酸加兰他敏,Narwedin

Target: AChE

Cat.No: T7891

Synonym: 伊匹达克林,NIK‐247

Target: Others

Cat.No: T21825

Target: Beta Amyloid, AChE

Neostigmine bromide

Cat.No: T1624

Synonym: Neoserine bromide,溴化新斯的明,Eustigmin bromide

Target: AChE

Aldicarb sulfone

Cat.No: T7640

Synonym: 得灭克,丁醛肟威,涕灭威砜

Target: AChE

Cat.No: T0229

Synonym: SDZ-ENA 713,卡巴拉汀,S-Rivastigmine,Exelon,利凡斯的明

Target: AChE

Cat.No: T1635

Synonym: Ronnel,Dermafos,皮蝇磷

Target: AChE, Parasite

Cat.No: T20812

Synonym: 甲基吡啶磷,唑啶磷

Target: AChE

Drofenine hydrochloride

Cat.No: T0713

Synonym: 盐酸六氢芬宁,Hexahydroadiphenine hydrochloride

Target: AChE

Rivastigmine tartrate

Cat.No: T1628

Synonym: SDZ-ENA 713,ENA 713,酒石酸卡巴拉汀

Target: AChR, AChE

Pyridostigmine bromide

Cat.No: T0780

Synonym: 溴吡斯的明,Mestinon,溴化吡啶斯的明

Target: AChE

Demecarium bromide

Cat.No: T7213

Synonym: 地美溴铵,BC-48

Target: AChE

Benactyzine hydrochloride

Cat.No: T2571

Synonym: Neuroleptone,胃复康,盐酸贝那替嗪,Tranquilline,Amitakon

Target: AChR, AChE

Cat.No: T21439

Synonym: 他克林,CS 12602,Tacrinum,Tetrahydroaminocrine

Target: AChR

Cat.No: T7041

Synonym: E2020,Donepezilo,Aricept,多奈哌齐

Target: AChE

Pitofenone hydrochloride

Cat.No: T4466

Synonym: Baralgin Ketone Hydrochloride,Pitophenone hydrochloride,吡托非农盐酸盐

Target: AChE

Cat.No: T22545

Synonym: acetylphosphoramidothioicacido,s-dimethylester,Ortran,Orthene,Acetamidophos,chevronorthene,乙酰甲胺磷

Target: AChE

Tacrine hydrochloride (hydrate)

Cat.No: T2191

Synonym: Tacrine,他克林盐酸盐水合物,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine

Target: AChR, AChE

Neostigmine methyl sulfate

Cat.No: T1612

Synonym: Normastigmin,甲基硫酸新斯的明,甲硫酸新斯的明,Hodostin,Syntostigmin

Target: AChR, AChE

Hemicholinium 3

Cat.No: T2227

Synonym: 半胆碱基-3,Hemicholinium-3,Hemicholine

Target: Others, AChE

Cat.No: T1072

Synonym: Pridinol methanesulfonate,Α,Α-二苯基-1-哌啶丙醇(普立地诺甲磺酸盐 )

Target: AChR

4-Methylbenzylidene camphor

Cat.No: T7465

Synonym: Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC

Target: AChE

Donepezil Hydrochloride

Cat.No: T6478

Synonym: Aricept,BNAG,E2020,Donepezil HCl,盐酸多奈哌齐

Target: AChR, AChE

Itopride hydrochloride

Cat.No: T1552

Synonym: 盐酸伊托必利,HSR803,盐酸依托必利,Ganaton

Target: Dopamine Receptor, AChE

Trihexyphenidyl hydrochloride

Cat.No: T7002

Synonym: Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride,盐酸苯海索

Target: AChR

Pralidoxime Chloride

Cat.No: T1111

Synonym: 2-PAM chloride,吡啶醛肟甲氯,2-Pyridinealdoxime methochloride,2-PAM (chloride)

Target: AChE

Acotiamide monohydrochloride trihydrate

Cat.No: T2319

Synonym: Acotiamide hydrochloride,YM-443 HCl,盐酸阿考替胺,Z-338 HCl

Target: AChE

Pirimiphos-methyl

Cat.No: T20539

Synonym: R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic

Target: AChE, Parasite

Protriptyline hydrochloride

Cat.No: T0204

Synonym: 盐酸普罗替林,Protriptyline HCl

Target: 5-HT Receptor, AChE

AChE/BuChE-IN-4

Cat.No: T77758

Target: AChE

Chenodeoxycholic Acid sodium salt

Cat.No: T65070

Synonym: CDCA sodium salt

Target: FXR

AChE/BChE/MAO-B-IN-1

Cat.No: T60891

Target: MAO, AChE

Cat.No: T72066

Target: Potassium Channel

Cat.No: T40335

Target: NO Synthase, AChE

CHEMBL1276927

Cat.No: T60092

Synonym: N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide,N-[3-(1H-苯并[d]咪唑-2-基)苯基]-3-甲基苯甲酰胺

Target: Antibacterial, Parasite

Cat.No: T14858

Synonym: Calicheamicin γ1,卡奇霉素

Target: Others, ADC Cytotoxin

Cat.No: T80671

Synonym: 5,6-Dimethoxy-2-(piperidin-4-yl)methylene-indan-1-one

Target: Antifungal

Dimethylaminomicheliolide HCl

Cat.No: T60102L

Target: PKM

AChE/BChE-IN-10

Cat.No: T61969

Target: AChR, AChE

Cat.No: T10630

Synonym: TM-10

Target: AChR

Deferasirox (Fe3+ chelate)

Cat.No: T13639

Target: Apoptosis

Chelidamic acid

Cat.No: T5884

Synonym: 4-氧代-1,4-二氢-2,6-吡啶二甲酸,白屈氨酸

Target: GluR

ACHE Inhibitor 12

Cat.No: T77352

Target: Others

Cat.No: T8598

Synonym: 2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE

Target: Adenosine Receptor

Chemerin-9 (149-157) acetate

Cat.No: TP1617L

Synonym: Chemerin-9 (149-157) acetate (676367-27-4 free base)

Target: Others

CHEMBL1380345

Cat.No: T60093

Synonym: N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)

Target: Antibacterial

Cat. No.	Product Name	Target	Signaling Pathways
TN1091	Dehydronuciferine	AChE	Neuroscience
	Dehydronuciferine 是一种乙酰胆碱酯酶抑制剂，其 IC50=25 μg/mL，是从 Nelumbo nucifera Gaertn 的叶子中分离得到。
T3852	Rhodiosin	Antioxidant; AChE	Neuroscience; oxidation-reduction
	Rhodiosin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂，IC50=0.761 μM，Ki=0.769 μM。它有 DPPH 自由基清除活性，IC50=27.7 μM。它抑制乙酰胆碱酯酶，IC50范围为 57.50 至 2.43 μg/mL。
T2846	Isoimperatorin	Antibacterial; AChE	Microbiology/Virology; Neuroscience
	Isoimperatorin 是 Angelica dahurica 根的甲醇提取物，是一种抗炎剂，有效抑制乙酰胆碱酯酶，IC50为 74.6 μM。
T13301	Violanthin	AChE	Neuroscience
	Violanthin 是一种从胡椒Piper bavinum 中分离出来，具有抗氧化和抗菌作用。它能够抑制乙酰胆碱酯酶，IC50=79.80 μM。
TN1011	Rhodionin	P450; AChE	Metabolism; Neuroscience
	Rhodionin 是从红景天的根中分离的特异性非竞争性细胞色素 P450 2D6 抑制剂，IC50=0.761 μM，Ki=0.769 μM。它有 DPPH 自由基清除活性，IC50为 19.49 μM。它抑制乙酰胆碱酯酶，IC50范围为 57.50 至 2.43 μg/mL。
T5855	Edrophonium chloride	AChE	Neuroscience
	Edrophonium chloride 是一种乙酰胆碱酯酶抑制剂，可通过特异性结合其催化位点来防止神经递质乙酰胆碱的分解。
T5S2361	Epiberberine	ERK; Beta-Secretase; MEK; BACE; AMPK; AChR; AChE	Chromatin/Epigenetic; MAPK; Neuroscience; PI3K/Akt/mTOR signaling
	Epiberberine 是一种从黄连中得到的生物碱，是AChE 和BChE 抑制剂，和非竞争性BACE1抑制剂。在 3T3-L1 细胞分化早期，它能够下调 Raf/MEK1/2/ERK1/2 和 AMPKα/Akt 信号通路。它具有抗氧化作用，能够清除 ONOO-，可用于阿尔滋海默症和糖尿病的研究。
TN1589	Dihydrowithaferin A	AChE	Neuroscience
	Dihydrowithaferin A 是一种从 Withania somnifera 中分离出来的 withanolide，具有抗乙酰胆碱酯酶 (AChE) 的活性。饮食中的Dihydrowithaferin A 可以预防或减少肿瘤的生长。
TN1899	Lycoramine	AChE	Neuroscience
	Lycoramine 是一种加兰他敏的二氢衍生物，从Lycoris radiate 中分离得到，是一种乙酰胆碱酯酶抑制剂。
T5S1408	Pteryxin 北美芹素,(+)-Pteryxin	Others; AChE	Neuroscience; Others
	Pteryxin ((+)-Pteryxin) 是一种白花前胡叶中的香豆素，是一种有效的丁酰胆碱酯酶(BChE)抑制剂，IC50=12.96 μg/ml，具有抗肥胖作用。
TN1858	Leptomerine	AChE	Neuroscience
	Leptomerine 是分离自Esenbeckia leiocarpaEngl. (Rutaceae) 茎中的生物碱。它抑制乙酰胆碱酯酶，IC50为 2.5 μM，具有抗胆碱能活性。它可用于研究阿尔茨海默症。
T13469	(±)-Huperzine A	AChE	Neuroscience
	(±)-Huperzine A 是一种从中药中提取的活性石松属生物碱。 (±)-Huperzine A 是一种特异性和可逆的乙酰胆碱酯酶抑制剂，可用于治疗阿尔茨海默病的研究。
T4S1725	Galanthamine Galantamine,加兰他敏	Apoptosis; AChE	Apoptosis; Neuroscience
	Galanthamine (Galantamine) 是一种乙酰胆碱酯酶抑制剂，IC50为 500 nM。
TN2298	Vincosamide 喜果苷	AChE	Neuroscience
	Vincosamide 是一种来自Psychotria leiocarpa 提取物的生物碱，具有抑制乙酰胆碱酯酶 (AChE) 作用，具有抗炎活性。
T13681	Epi-galantamine	AChE	Neuroscience
	Epi-galantamine 是 Galantamine 的非对映异构体，是从高加索雪花莲的鳞茎和花朵中分离出来的生物碱。它能够抑制AChE，EC50=45.7 μM 。
TN1786	Isomerazin Isomeranzin,异橙皮内酯	ERK; NF-κB; AChE	MAPK; Neuroscience; NF-κB
	Isomerazin (Isomeranzin) 是一种香豆素类化合物，分离于 Poncirus trifoliateRaf 中，具有胆碱酯酶抑制作用。
T3769	Tenuifolin	Others; Beta-Secretase; AChE	Neuroscience; Others
	Tenuifolin 是一种从远志中分离出的三萜，能够抑制β-secretase 以减少 Aβ 蛋白分泌，具有神经保护作用。它可通过降低 AChE 活性来改善衰老小鼠的学习和记忆能力，有潜力用于阿尔茨海默氏病的研究。
T6S2356	Corynoline 紫蓳灵,堇醇灵碱,(+)-Corynoline	Nrf2; AChE	Immunology/Inflammation; Neuroscience
	Corynoline ((+)-Corynoline) 是可逆和非竞争性的乙酰胆碱酯酶抑制剂，IC50=30.6 μM。它可激活 Nrf2，具有抗炎作用。
TN6919	Methyl tridecanoate	Beta Amyloid; AChE	Neuroscience
	Methyl tridecanoate 能够适度抑制 β-淀粉样蛋白聚集，弱抑制乙酰胆碱酯酶。
T2S1720	Huperzine B	AChE	Neuroscience
	Huperzine B 是一种从 Huperzia serrata 中分离出的石蒜生物碱，也是一种高度选择性的乙酰胆碱酯酶抑制剂，可以用于改善阿尔茨海默氏病。
TN1124	Neoeriocitrin	AChE	Neuroscience
	Neoeriocitrin 是一种有效的乙酰胆碱酯酶抑制剂，分离于自百日草，在 MC3T3-E1 中显示出对增殖和成骨分化的活性。
T4S1024	Picfeltarraenin IB 苦玄参苷IB,苦玄参苷 IB	Others; AChE	Neuroscience; Others
	Picfeltarraenin IB 是一种Picriafel-terraeLour (P.fel-terrae) 中提取的三萜类化合物，是一种乙酰胆碱酯酶抑制剂。它可用于感染，癌症和炎症的研究。
T5S2343	Acetylshikonin 乙酰紫草素,Acetyl shikonin	Others; P450; AChE	Metabolism; Neuroscience; Others
	Acetylshikonin 来源于紫草根，具有抗癌、抗炎作用。它是一种 AChE 抑制剂，具有很强的抗凋亡活性。它是一种非选择性的细胞色素 P450抑制剂，对所有 P450 亚型抑制的 IC50值范围为 1.4-4.0 μM。
T11351	Galanthamine N-Oxide	AChE	Neuroscience
	Galanthamine N-Oxide 是分离于Zephyranthes concolor 的球茎中的一种生物碱。它抑制电鳗乙酰胆碱酯酶，EC50=26.2 μM。它是TcAChE，hAChE 和 hBChE 酶活性位点中底物调节的显著抑制剂。
T3872	Nodakenin 紫花前胡苷,(+)-Marmesinin	AChE	Neuroscience
	Nodakenin ((+)-Marmesinin) 是一种Peucedanum decursivum Maxim 根中的主要香豆素苷。它能够抑制乙酰胆碱酯酶活性，IC50=84.7 μM。
T11366	Garcinol	Apoptosis; Endogenous Metabolite; Histone Acetyltransferase; AChR; AChE	Apoptosis; Chromatin/Epigenetic; Metabolism; Neuroscience
	Garcinol 是一种从印度藤黄提取的聚异戊二烯基二苯甲酮，对乙酰胆碱酯酶和丁酰胆碱酯酶具有抗胆碱酯酶的特性，IC50分别为 0.66 µM 和 7.39 µM。它还抑制组蛋白乙酰转移酶和 p300/CPB 相关因子，具有抗炎和抗癌活性。
T8306	Epiberberine chloride	Antioxidant; BACE; AChR; AChE	Neuroscience; oxidation-reduction
	Epiberberine chloride 是一种来自Coptis chinensis Franch.的天然原小檗碱，是 AChE、 BChE 和 BACE1 抑制剂，IC50 值分别为 1.07，6.03 和 8.55 μM。Epiberberine chloride 具有抗氧化作用，抑制Ca9-22和FaDu细胞系的运动，可用于研究高脂血症、阿尔滋海默症和糖尿病。
T5S1025	Picfeltarraenin IA 苦玄参苷IA,Picfeltarraenin A,苦玄参苷 IA	AChE	Neuroscience
	Picfeltarraenin IA (Picfeltarraenin A) 是一种Picriafel-terraeLour (P.fel-terrae) 中提取的三萜类化合物，是一种乙酰胆碱酯酶抑制剂。它可用于感染，癌症和炎症的研究。
Fr14127	Coumaran 2,3-Dihydrobenzofuran,2,3-二氢苯并呋喃	Endogenous Metabolite; AChE	Metabolism; Neuroscience
	Coumaran (2,3-Dihydrobenzofuran) 是一种提取自L. camara 的 (AChE) 抑制剂。2,3-Dihydrobenzofuran 能够用作生物农药。
T0130	Physostigmine Salicylate 水杨酸依色林,水杨酸毒扁豆碱	AChR; AChE	Neuroscience
	Physostigmine salicylate 是一种可逆的乙酰胆碱酯酶抑制剂，也一种是抗胆碱能中毒的解毒剂。它可透过血脑屏障并刺激中枢胆碱能神经传递。它能逆转阿尔茨海默病转基因小鼠的记忆缺陷。
T5S2254	Swertianolin Bellidifolin-8-O-Glucoside,当药醇苷	Others; HBV; Antibacterial; AChE	Microbiology/Virology; Neuroscience; Others
	Swertianolin (Bellidifolin-8-O-Glucoside) 是从Gentianella Acuta 分离得到的一种黄酮，具有抗 HBV 和抗菌活性，可抑制乙酰胆碱酯酶。
T3767	Polygalacic acid Virgaureagenin G,毛果一枝黄花皂苷元G,远志酸	MMP; AChR; AChE	Neuroscience; Proteases/Proteasome
	Polygalacic acid (Virgaureagenin G) 是一种从远志 Polygala tenuifolia Willd 根中分离出来的三萜，可抑制 MMP 表达。它对认知障碍有显著的神经保护作用，PA 通过抑制乙酰胆碱酯酶活性，增加胆碱乙酰转移酶活性，提高海马和额皮质中的乙酰胆碱水平来提高胆碱能系统反应性。它可以用于骨关节炎相关研究。
T3395	Timosaponin AIII Filiferin B,知母皂苷 A-III,AneMarsaponin A3,Timosaponin A3	AChE; mTOR	Neuroscience; PI3K/Akt/mTOR signaling
	Timosaponin AIII (Timosaponin A3) 是一种乙酰胆碱酯酶活性抑制剂，其IC50=35.4 μM。
T9862	Pseudocoptisine chloride 盐酸异黄连碱,Isocoptisine chloride	AChE	Neuroscience
	Pseudocoptisine chloride (Isocoptisine chloride) 是从 Corydalis Tuber 中分离出来的，具有抗炎和抗健忘的作用。 Pseudocoptisine chloride 抑制乙酰胆碱酯酶 (AChE) 活性 (IC50 = 12.8 μM)。
TN6786	O-Desmethyl Galanthamine Sanguinine,O-去甲基加兰他敏	AChE	Neuroscience
	O-Desmethyl Galanthamine (Sanguinine) 是一种加兰他敏型生物碱，是一种乙酰胆碱酯酶 (AChE) 抑制剂，其IC50=1.83 μM。
TN1030	N-p-trans-Coumaroyltyramine N-反式对香豆酰基酪胺,N-反式-对香豆酰酪胺	AChE; Parasite	Microbiology/Virology; Neuroscience
	N-p-trans-Coumaroyltyramine 是从蓼属植物中分离出的肉桂酰苯乙酰胺，是一种乙酰胆碱酯酶抑制剂，IC50 为 122 μM。它具有抗锥虫活性，对T. brucei rhodesiense 作用的 IC50值为 13.3 µM。
T6S0653	Linarin Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷	TNF; AChE	Apoptosis; Neuroscience
	Linarin (Acacetin-7-O-rutinoside) 是一种选择性的乙酰胆碱酯酶 (AChE) 抑制剂，从薄荷花提取物中分离得到。
T5S2360	Corydaline Corydalin,紫堇碱,延胡索甲素,(+)-Corydaline	P450; Virus Protease; Opioid Receptor; AChE	Endocrinology/Hormones; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Corydaline (Corydalin) 是从 Corydalis yanhusuo 提取的一种异喹啉生物碱，是一种新型促动力植物药的主要活性成分之一。它促进胃排空和小肠转运，促进胃的调节，具有抗乙酰胆碱酯酶、抗过敏和镇痛活性。
T0086	Galanthamine hydrobromide Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏	AChR; AChE	Neuroscience
	Galanthamine hydrobromide (Galantamine hydrobromide) 是一种长效的中枢活性 AChE 抑制剂，IC50为 410 nM。它是神经元烟碱型 ACh 受体的变构增强剂，IC50值为 0.35 µM，可用于阿尔茨海默症的研究。
T2845	Imperatorin Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen	TRP/TRPV Channel; AChR; AChE; NOD	Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB
	Imperatorin (8-Isopentenyloxypsoralene) 是NO synthesis 和BChE 的抑制剂，IC50分别为 9.2 μmol 和 31.4 μmol。它也是TRPV1的微弱激动剂，EC50为 12.6±3.2 μM。
T2S1200	Sinapine	Antioxidant; P-gp; AChE	Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
	Sinapine 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
T3392	Sinapine thiocyanate	P-gp; AChE	Membrane transporter/Ion channel; Neuroscience
	Sinapine thiocyanate 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
T2984	Scopoletin Chrysatropic acid,东莨菪内酯,Esculetin 6-methyl ether,Gelseminic acid,6-Methylesculetin	Apoptosis; AChR; AChE	Apoptosis; Neuroscience
	Scopoletin (Esculetin 6-methyl ether) 是一种源自东莨菪根的植物生长因子，可抑制乙酰胆碱酯酶。
T3933	Jatrorrhizine Yatrorizine,neprotin,药根碱	MAO; 5-HT Receptor; Antibacterial; AChE	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Jatrorrhizine (neprotin) 是一种从黄连中分离得到的生物碱，具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。
T3026	(-)-Huperzine A HupA,石杉碱,Huperzine A,石杉碱甲	Apoptosis; AChR; AChE; iGluR	Apoptosis; Membrane transporter/Ion channel; Neuroscience
	(-)-Huperzine A (HupA) 是从中国梅花苔中分离得到的一种生物碱，具有神经保护活性。它是高特异性可逆的，具有血脑屏障渗透性的一种乙酰胆碱酯酶抑制剂，其IC50值为 82 nM。它也是 N-甲基-D-天冬氨酸受体的非竞争性拮抗剂，可研究神经退行性疾病，如阿尔茨海默病。
T4852	Trimyristin Trimyristoylglycerol,Tritetradecanoin,三肉豆蔻酸甘油酯,Glyceryl trimyristate,甘油三肉豆蔻酸酯,1,2,3-Tritetradecanoylglycerol	Phosphatase; Endogenous Metabolite; AChE	Metabolism; Neuroscience
	Trimyristin (Tritetradecanoin) 是一种 Myristica fragransHoutt 的有效成分，能够显著抑制乙酰胆碱酯酶 (AChE)，酸性和碱性磷酸酶 (ACP/ALP) 特性。它对 AChE，ACP 和 ALP 的 IC50分别为 0.11、0.16 和 0.18 mM。
TN2130	Manghaslin 槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside	AChE; Glucosidase	Metabolism; Neuroscience
	Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) 是具有抗炎活性的黄酮苷，对 AChE 具有抑制活性，IC50=94.92 µM。
T4912	Jatrorrhizine chloride 盐酸药根碱,Yatrorhizine chloride,Neprotine chloride	Others; 5-HT Receptor; OCT; Antibacterial; AChE	GPCR/G Protein; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others
	Jatrorrhizine chloride (Neprotine chloride) 是从黄连中分离得到的生物碱，具有神经保护、抗菌、抗氧化和抗疟原虫活性。它通过抑制摄取2转运蛋白的活性减少血清素和去甲肾上腺素的摄取。它是具有口服活性的乙酰胆碱酯酶抑制剂。
T2S0491	Isoeugenol acetate 乙酸异丁香酚酯,Isoeugenyl acetate,Acetisoeugenol,Acetylisoeugenol,乙酸异丁香酚酯，乙酰基异丁香酚;2-甲氧基-4-丙烯基苯基乙酸酯	AChE; Antifungal	Microbiology/Virology; Neuroscience
	Isoeugenol acetate (Acetylisoeugenol) 是肉豆蔻，丁香和肉桂的精油成分，对某些代谢酶如乙酰胆碱酯酶，能够抑制α-糖苷酶和 α-淀粉酶。它用于医疗和化妆品工业，具有抗氧化，抗癌，抗菌和抗炎作用。
T4439	sn-Glycero-3-phosphocholine Choline Alfoscerate,甘磷酸胆碱,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC	Endogenous Metabolite; AChE	Metabolism; Neuroscience
	sn-Glycero-3-phosphocholine (Choline glycerophosphate) 是脑磷脂生物合成的前体，能够提高胆碱在神经组织中的生物利用度。它对认知功能有显著影响，同时具有良好的耐受性和安全性，因此能够用于阿尔茨海默病和痴呆症的研究。
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天然产物

Dehydronuciferine

Cat.No: TN1091

Target: AChE

Cat.No: T3852

Target: Antioxidant, AChE

Cat.No: T2846

Target: Antibacterial, AChE

Cat.No: T13301

Target: AChE

Cat.No: TN1011

Target: P450, AChE

Edrophonium chloride

Cat.No: T5855

Target: AChE

Cat.No: T5S2361

Target: ERK, Beta-Secretase, MEK, BACE, AMPK, AChR, AChE

Dihydrowithaferin A

Cat.No: TN1589

Target: AChE

Cat.No: TN1899

Target: AChE

Cat.No: T5S1408

Synonym: 北美芹素,(+)-Pteryxin

Target: Others, AChE

Cat.No: TN1858

Target: AChE

(±)-Huperzine A

Cat.No: T13469

Target: AChE

Cat.No: T4S1725

Synonym: Galantamine,加兰他敏

Target: Apoptosis, AChE

Cat.No: TN2298

Synonym: 喜果苷

Target: AChE

Epi-galantamine

Cat.No: T13681

Target: AChE

Cat.No: TN1786

Synonym: Isomeranzin,异橙皮内酯

Target: ERK, NF-κB, AChE

Cat.No: T3769

Target: Others, Beta-Secretase, AChE

Cat.No: T6S2356

Synonym: 紫蓳灵,堇醇灵碱,(+)-Corynoline

Target: Nrf2, AChE

Methyl tridecanoate

Cat.No: TN6919

Target: Beta Amyloid, AChE

Cat.No: T2S1720

Target: AChE

Cat.No: TN1124

Target: AChE

Picfeltarraenin IB

Cat.No: T4S1024

Synonym: 苦玄参苷IB,苦玄参苷 IB

Target: Others, AChE

Cat.No: T5S2343

Synonym: 乙酰紫草素,Acetyl shikonin

Target: Others, P450, AChE

Galanthamine N-Oxide

Cat.No: T11351

Target: AChE

Cat.No: T3872

Synonym: 紫花前胡苷,(+)-Marmesinin

Target: AChE

Cat.No: T11366

Target: Apoptosis, Endogenous Metabolite, Histone Acetyltransferase, AChR, AChE

Epiberberine chloride

Cat.No: T8306

Target: Antioxidant, BACE, AChR, AChE

Picfeltarraenin IA

Cat.No: T5S1025

Synonym: 苦玄参苷IA,Picfeltarraenin A,苦玄参苷 IA

Target: AChE

Cat.No: Fr14127

Synonym: 2,3-Dihydrobenzofuran,2,3-二氢苯并呋喃

Target: Endogenous Metabolite, AChE

Physostigmine Salicylate

Cat.No: T0130

Synonym: 水杨酸依色林,水杨酸毒扁豆碱

Target: AChR, AChE

Cat.No: T5S2254

Synonym: Bellidifolin-8-O-Glucoside,当药醇苷

Target: Others, HBV, Antibacterial, AChE

Polygalacic acid

Cat.No: T3767

Synonym: Virgaureagenin G,毛果一枝黄花皂苷元G,远志酸

Target: MMP, AChR, AChE

Timosaponin AIII

Cat.No: T3395

Synonym: Filiferin B,知母皂苷 A-III,AneMarsaponin A3,Timosaponin A3

Target: AChE, mTOR

Pseudocoptisine chloride

Cat.No: T9862

Synonym: 盐酸异黄连碱,Isocoptisine chloride

Target: AChE

O-Desmethyl Galanthamine

Cat.No: TN6786

Synonym: Sanguinine,O-去甲基加兰他敏

Target: AChE

N-p-trans-Coumaroyltyramine

Cat.No: TN1030

Synonym: N-反式对香豆酰基酪胺,N-反式-对香豆酰酪胺

Target: AChE, Parasite

Cat.No: T6S0653

Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷

Target: TNF, AChE

Cat.No: T5S2360

Synonym: Corydalin,紫堇碱,延胡索甲素,(+)-Corydaline

Target: P450, Virus Protease, Opioid Receptor, AChE

Galanthamine hydrobromide

Cat.No: T0086

Synonym: Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏

Target: AChR, AChE

Cat.No: T2845

Synonym: Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen

Target: TRP/TRPV Channel, AChR, AChE, NOD

Cat.No: T2S1200

Target: Antioxidant, P-gp, AChE

Sinapine thiocyanate

Cat.No: T3392

Target: P-gp, AChE

Cat.No: T2984

Synonym: Chrysatropic acid,东莨菪内酯,Esculetin 6-methyl ether,Gelseminic acid,6-Methylesculetin

Target: Apoptosis, AChR, AChE

Cat.No: T3933

Synonym: Yatrorizine,neprotin,药根碱

Target: MAO, 5-HT Receptor, Antibacterial, AChE

(-)-Huperzine A

Cat.No: T3026

Synonym: HupA,石杉碱,Huperzine A,石杉碱甲

Target: Apoptosis, AChR, AChE, iGluR

Cat.No: T4852

Synonym: Trimyristoylglycerol,Tritetradecanoin,三肉豆蔻酸甘油酯,Glyceryl trimyristate,甘油三肉豆蔻酸酯,1,2,3-Tritetradecanoylglycerol

Target: Phosphatase, Endogenous Metabolite, AChE

Cat.No: TN2130

Synonym: 槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside

Target: AChE, Glucosidase

Jatrorrhizine chloride

Cat.No: T4912

Synonym: 盐酸药根碱,Yatrorhizine chloride,Neprotine chloride

Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE

Isoeugenol acetate

Cat.No: T2S0491

Synonym: 乙酸异丁香酚酯,Isoeugenyl acetate,Acetisoeugenol,Acetylisoeugenol,乙酸异丁香酚酯，乙酰基异丁香酚;2-甲氧基-4-丙烯基苯基乙酸酯

Target: AChE, Antifungal

sn-Glycero-3-phosphocholine

Cat.No: T4439

Synonym: Choline Alfoscerate,甘磷酸胆碱,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC

Target: Endogenous Metabolite, AChE

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01693	Butyrylcholinesterase Protein, Human, Recombinant (His) CHE1,E1,butyrylcholinesterase,CHE2	Human	HEK293 Cells
	Butyrylcholinesterase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.5 kDa and the accession number is P06276.
TMPY-00367	Chemerin/RARRES2 Protein, Mouse, Recombinant (His) AI303516,retinoic acid receptor responder (tazarotene induce...	Mouse	HEK293 Cells
	Chemerin/RARRES2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is Q9DD06.
TMPJ-01292	Chemerin/RARRES2 Protein, Human, Recombinant (His) RAR-responsive protein TIG2,RARRES2,Chemerin,Tazaro...	Human	HEK293 Cells
	Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon. It is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1. RARRES2 is secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. It is thou...
TMPH-00754	Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) Gene product D,Auxiliary protein D,Major capsid protein D,gp...	Escherichia phage lambda	E. coli
	Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. 415 capsid decoration protein molecules cooperatively bind the expanded capsid, thereby stabilizing the mature capsid shell. Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) is expressed in E. coli expression system with N-GST...
TMPY-04143	Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc) 0610007L05Rik,retinoic acid receptor responder (tazarotene i...	Mouse	HEK293 Cells
	Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.6 kDa and the accession number is Q9DD06.
TMPY-04435	CHEK2 Protein, Mouse, Recombinant (His & GST) Rad53,CHK2,checkpoint kinase 2,Cds1,HUCDS1	Mouse	Baculovirus Insect Cells
	CHEK2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89 kDa and the accession number is Q9Z265.
TMPY-06677	Bla g 4 Protein, cockroaches, Recombinant	cockroaches	P. pastoris (Yeast)
	Bla g 4 Protein, cockroaches, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 30 kDa.
TMPY-04681	CHEK2 Protein, Human, Recombinant (GST) CDS1,HuCds1,checkpoint kinase 2,hCds1,LFS2,RAD53,CH...	Human	Baculovirus Insect Cells
	CHEK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 88.1 kDa and the accession number is O96017-1.
TMPH-00755	Integrase Protein, Escherichia phage lambda, Recombinant (His) Integrase,int	Escherichia phage lambda	E. coli
	Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Integrase Protein, Escherichia phage lambda, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.3 kDa and the accession number is P03700.
TMPH-00159	Subtilisin Carlsberg Protein, Bacillus licheniformis, Recombinant (His & SUMO) subC,Subtilisin Carlsberg	Bacillus licheniformis	E. coli
	Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides (Ref.4, PubMed:11109488). Shows high specificity for aromatic and hydrophobic amino acids in the P1 substrate position. May play an important role in the degradation of feather keratin. Subtilisin Carlsberg Protein, Bacillus licheniformis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 42.0 kDa and the ac...
TMPH-01332	Ferrochelatase Protein, Human, Recombinant (His & Myc) Ferrochelatase, mitochondrial,Heme synthase,Protohe...	Human	E. coli
	Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6 kDa and the accession number is P22830.
TMPY-05906	Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H1N1	HEK293 Cells
	Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is A0A0U4T2C2.
TMPH-03529	Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His) CHIPS,Chemotaxis inhibitory protein,chp	Staphylococcus aureus	P. pastoris (Yeast)
	Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Re...
TMPH-03528	Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc) chp,Chemotaxis inhibitory protein,CHIPS	Staphylococcus aureus	E. coli
	Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS...
TMPH-00756	Capsid Protein, Escherichia phage MS2, Recombinant (His & Myc) CP,Capsid protein,Coat protein	Escherichia phage MS2	E. coli
	Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 26 nm in diameter, and consisting of 89 capsid proteins dimers (178 capsid proteins). Involved in viral genome encapsidation through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome. The capsid contains also 1 copy of the A2 maturation protein.; Acts as a translational repressor of viral replicase synthesis late in infection. This latter function is th...
TMPH-03195	Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc) Protein archease	Pyrococcus horikoshii	E. coli
	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.1 kDa and the accession number is O59205...
TMPH-00265	Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) Ferrochelatase, mitochondrial,Protoheme ferro-lyase...	Bovine	E. coli
	Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Mycd tag. The predicted molecular weight is 58.1 kDa and the accession number is P22600.

重组蛋白

Butyrylcholinesterase Protein, Human, Recombinant (His)

Cat.No: TMPY-01693

Species: Human

Expression System: HEK293 Cells

Chemerin/RARRES2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00367

Species: Mouse

Expression System: HEK293 Cells

Chemerin/RARRES2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01292

Species: Human

Expression System: HEK293 Cells

Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST)

Cat.No: TMPH-00754

Species: Escherichia phage lambda

Expression System: E. coli

Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04143

Species: Mouse

Expression System: HEK293 Cells

CHEK2 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-04435

Species: Mouse

Expression System: Baculovirus Insect Cells

Bla g 4 Protein, cockroaches, Recombinant

Cat.No: TMPY-06677

Species: cockroaches

Expression System: P. pastoris (Yeast)

CHEK2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04681

Species: Human

Expression System: Baculovirus Insect Cells

Integrase Protein, Escherichia phage lambda, Recombinant (His)

Cat.No: TMPH-00755

Species: Escherichia phage lambda

Expression System: E. coli

Subtilisin Carlsberg Protein, Bacillus licheniformis, Recombinant (His & SUMO)

Cat.No: TMPH-00159

Species: Bacillus licheniformis

Expression System: E. coli

Ferrochelatase Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01332

Species: Human

Expression System: E. coli

Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-05906

Species: H1N1

Expression System: HEK293 Cells

Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)

Cat.No: TMPH-03529

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc)

Cat.No: TMPH-03528

Species: Staphylococcus aureus

Expression System: E. coli

Capsid Protein, Escherichia phage MS2, Recombinant (His & Myc)

Cat.No: TMPH-00756

Species: Escherichia phage MS2

Expression System: E. coli

Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc)

Cat.No: TMPH-03195

Species: Pyrococcus horikoshii

Expression System: E. coli

Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00265

Species: Bovine

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T13446	(S)-Rivastigmine D6 tartrate 酒石酸卡巴拉汀 D6,(R)-卡巴拉汀酒石盐酸-D6,(R)-Rivastigmine D6 tartrate	AChE	Neuroscience
	(S)-Rivastigmine D6 tartrate 是一种 (S)-Rivastigmine 氘代化合物。
TMIH-0518	SCHEMBL19801452-d3
	SCHEMBL19801452-d3 是 SCHEMBL19801452 的氘代化合物。SCHEMBL19801452 的 CAS 号为 2173409-13-5。
TMIH-0145	Chenodeoxycholic Acid-d4
	Chenodeoxycholic Acid-d4 是 Chenodeoxycholic Acid 的氘代化合物。
TMIH-0286	Isochenodeoxycholic Acid-d4
	Isochenodeoxycholic Acid-d4 是 Isochenodeoxycholic Acid 的氘代化合物。Isochenodeoxycholic Acid 的 CAS 号为 566-24-5。
TMIH-0254	Glycochenodeoxycholic Acid-d4
	Glycochenodeoxycholic Acid-d4 是 Glycochenodeoxycholic Acid 的氘代化合物。
TMIJ-0198	Taurochenodeoxycholic Acid-d5 Sodium Salt
	Taurochenodeoxycholic Acid-d5 Sodium Salt 是 Taurochenodeoxycholic Acid Sodium Salt 的氘代化合物。Taurochenodeoxycholic Acid Sodium Salt 的 CAS 号为 6009-98-9。Taurochenodeoxycholic acid sodium 是动物胆汁酸的主要生物活性物质之一。它可诱导细胞凋亡，具有抗炎和免疫调节作用。

同位素标记化合物

(S)-Rivastigmine D6 tartrate

Cat.No: T13446

Synonym: 酒石酸卡巴拉汀 D6,(R)-卡巴拉汀酒石盐酸-D6,(R)-Rivastigmine D6 tartrate

Target: AChE

SCHEMBL19801452-d3

Cat.No: TMIH-0518

Chenodeoxycholic Acid-d4

Cat.No: TMIH-0145

Isochenodeoxycholic Acid-d4

Cat.No: TMIH-0286

Glycochenodeoxycholic Acid-d4

Cat.No: TMIH-0254

Taurochenodeoxycholic Acid-d5 Sodium Salt

Cat.No: TMIJ-0198

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