Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02876 |
RIPK1 Protein, Mouse, Recombinant (His)
Cell death protein RIP,R... |
Mouse | E. coli |
Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways. Exhibits kinase activity-dependent functions that regulate cell death and kinase-independent scaffold functions regulating inflammatory signaling and cell survival. Has kinase-independent scaffold functions: upon binding of TNF to TNFR1, RIPK1 is recruited to the TNF-R1 signaling complex (TNF-RSC also known as complex I) where it acts as a scaffold protein promoting cell survival, i... | |||
TMPH-02007 |
RIPK1 Protein, Human, Recombinant (His & Myc)
Receptor-interacting protein 1,Receptor-interacting... |
Human | E. coli |
RIPK1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.4 kDa and the accession number is Q13546. | |||
TMPJ-01059 |
CRADD Protein, Human, Recombinant
Caspase and RIP Adapter with Death Domain,... |
Human | E. coli |
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numero... |