73
4
19
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T64350 |
Casein kinase 1δ-IN-3
|
Casein Kinase | Metabolism; Stem Cells |
Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) 是一种酪蛋白激酶 1δ (CK1d) 抑制剂,pIC50 为 6.5376。 | |||
T64376 |
Casein kinase 1δ-IN-9
|
NADPH | Metabolism |
Casein kinase 1δ-IN-9是一种醌还原酶2(Quinone reductase 2)抑制剂,IC50为0.6μM。 | |||
T77500 |
Casein kinase 1δ-IN-6
|
Casein Kinase | Metabolism; Stem Cells |
Casein kinase 1δ-IN-6 是一种有效且具有选择性的蛋白激酶 CK-1δ 抑制剂,其 IC50 为 23 nM。Casein kinase 1δ-IN-6 在体外和体内实验中均显示出神经保护和抗炎活性。Casein kinase 1δ-IN-6 可用于研究神经退行性疾病。 | |||
T10687 |
Casein Kinase II Inhibitor IV
|
Casein Kinase | Metabolism; Stem Cells |
Casein Kinase II Inhibitor IV 是一种小分子诱导剂,可诱导表皮角质形成细胞分化。 | |||
T9175 |
Casein Kinase inhibitor A51
|
Apoptosis; Casein Kinase | Apoptosis; Metabolism; Stem Cells |
Casein Kinase inhibitor A51 是一种具有口服活性的酪蛋白激酶 1α (CK1α) 抑制剂,具有抗癌活性,可诱导白血病细胞凋亡 (apoptosis),可用于研究颈部癌、急性髓系白血病、乳腺癌和前列腺癌。 | |||
T77648 |
Casein kinase 1δ-IN-14
WAY-637081 |
Others | Others |
Casein kinase 1δ-IN-14(WAY-637081) 可用于研究动脉粥样硬化相关心血管疾病。 | |||
T60295 |
Casein kinase 1δ-IN-1
WAY-643895 |
Casein Kinase | Metabolism; Stem Cells |
Casein kinase 1δ-IN-1 (WAY-643895) 是一种酪蛋白激酶 1δ (CK1δ) 的抑制剂,对CK1δ有抑制作用。Casein kinase 1δ-IN-1 可用于如阿尔茨海默病类的神经退行性疾病的研究。 | |||
T39482 |
Casein Kinase inhibitor A86
Casein Kinase inhibitor A86 |
Others | Others |
Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α). Additionally, it displays inhibitory actions towards CDK7 (TFIIH) and CDK9 (P-TEFb). Furthermore, Casein Kinase inhibitor A86 demonstrates the ability to induce apoptosis in leukemia cells, portraying substantial anti-leukemic effects. | |||
T77708 |
Casein kinase 1δ-IN-7
|
Casein Kinase | Metabolism; Stem Cells |
Casein kinase 1δ-IN-7 是一种 Casein kinase 1δ 抑制剂,可用于阿尔茨海默氏病等神经退行性疾病的研究。 | |||
T77709 |
Casein kinase 1δ-IN-8
|
Casein Kinase | Metabolism; Stem Cells |
Casein kinase 1δ-IN-8 是一种酪蛋白激酶 1δ 的抑制剂,可用于治疗如阿尔茨海默病类型的神经退行性疾病。 | |||
T2695 |
TBB
Casein Kinase II Inhibitor I,NSC 231634,4,5,6,7-tetrabromobenzotriazole |
GSK-3; Casein Kinase; CDK | Cell Cycle/Checkpoint; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells |
TBB (NSC-231634) 是一种高选择性的 ATP/GTP 竞争性酪蛋白激酶 2 (CK2) 抑制剂,可抑制大鼠肝脏 CK2,IC50值为0.15 μM。 | |||
T2449 |
D4476
D 4476,Casein Kinase I Inhibitor |
Apoptosis; Casein Kinase; ALK; Autophagy | Angiogenesis; Apoptosis; Autophagy; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors |
D4476 (Casein Kinase I Inhibitor) 是一种选择性和细胞渗透性的CK1抑制剂,在体外实验的IC50值为0.3 μM。 | |||
T21915 |
TBCA
Casein Kinase II Inhibitor III, TBCA |
Casein Kinase | Metabolism; Stem Cells |
TBCA (Casein Kinase II Inhibitor III, TBCA) 是高选择性的酪蛋白激酶II CK2 抑制剂,IC50 为 110 nM,Ki 为 77 nM。TBCA 对 CK1、DYRK1A 和 其它 27 个激酶表现出选择性。 | |||
TP1509 |
Casein Kinase Substrates 3
|
||
Casein Kinase Substrates 3 is a substrate of casein kinase. | |||
T7390 |
DMAT
Casein kinase II Inhibitor,2-二甲基氨基-4,5,6,7-四溴苯并咪唑,CK2 Inhibitor |
Casein Kinase | Metabolism; Stem Cells |
DMAT (Casein kinase II Inhibitor) 是一种特异性 CK2抑制剂,IC50值为 130 nM。 | |||
T10687L |
Casein Kinase II Inhibitor IV Hydrochloride
Casein Kinase II Inhibitor IV Hydrochloride (863598-09-8 free base) |
Others | Others |
Casein Kinase II Inhibitor IV Hydrochloride 是一种表皮角质形成细胞分化的小分子诱导剂,可用于机制研究,并具有治疗皮肤过度增生性疾病的研究潜力。 | |||
T5358 |
Longdaysin
|
ERK; Casein Kinase; CDK | Cell Cycle/Checkpoint; MAPK; Metabolism; Stem Cells |
Longdaysin 是一种 CK1α 和 CK1δ 的抑制剂,IC50为5.6和8.8 µM。它还抑制ERK2,IC50值为52 µM。它是Wnt/β-catenin 信号通路的抑制剂,通过阻断CK1δ/ε依赖性 Wnt 信号通路发挥抗肿瘤作用。 | |||
T3972 |
SR-3029
SR3029 |
Casein Kinase | Metabolism; Stem Cells |
SR-3029 具有 ATP 竞争性,有效抑制 CK1δ和 CK1ε,IC50值分别为 44 nM 和 260 nM,Ki 均为 97 nM。 | |||
T14069 |
A-3 hydrochloride
|
CaMK; Casein Kinase; PKA; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Neuroscience; Stem Cells; Tyrosine Kinase/Adaptors |
A-3 hydrochloride 是一种细胞可渗透的、可逆的、ATP 竞争性非选择性拮抗剂。它抑制 PKA 、酪蛋白激酶 II 和肌球蛋白轻链激酶,Ki 值分别为4.3 µM、5.1 µM 和7.4 µM。它还抑制 PKC 和酪蛋白激酶 I 的活性,Ki 分别为 47 µM 和 80 µM。 | |||
T3073 |
PF-670462
PF670462 |
Casein Kinase | Metabolism; Stem Cells |
PF-670462 是一种选择性酪蛋白激酶 (CK1δ/ε)抑制剂,IC50值分别为 14 nM 和 7.7 nM。 | |||
T7949 |
NCC007
|
Casein Kinase | Metabolism; Stem Cells |
NCC007 是一种双酪蛋白激酶 Iα(CKIα)和 δ(CKIδ)抑制剂,IC50分别为 1.8 和 3.6 μM。它通过对 longdaysin 的 N9和 C2位进行结构修饰,可研究哺乳动物昼夜节律周期。 | |||
T5056 |
PF-4800567
|
Casein Kinase | Metabolism; Stem Cells |
PF-4800567 是酪蛋白激酶 1ε (CK1ε) 的选择性抑制剂,IC50为 32 nM,对其选择性是对 CK1δ 的 20 倍,IC50为711 nM。 | |||
T1828 |
TTP 22
|
Casein Kinase | Metabolism; Stem Cells |
TTP 22 是一种高亲和力、ATP 竞争性酪蛋白激酶 2 抑制剂,IC50和 Ki 值分别为 0.1 uM 和 40 nM。 | |||
T5393 |
CK1-IN-1
PUN51207 |
p38 MAPK; Casein Kinase | MAPK; Metabolism; Stem Cells |
CK1-IN-1 (PUN51207) 是一种酪蛋白激酶 1 抑制剂,对 CK1δ、CK1ε和p38σ MAPK 的IC50值为 15 nM、16 nM 和73 nM。 | |||
T4645 |
TA-01
|
p38 MAPK; Casein Kinase; Autophagy | Autophagy; MAPK; Metabolism; Stem Cells |
TA01 是一种心源性抑制剂,有效抑制CK1和p38 MAPK,其对 CK1ε,CK1δ 和 p38 MAPK 的IC50值分别为 6.4 nM,6.8 nM 和 6.7 nM。 | |||
T2702 |
IWP-2
IWP2 |
Casein Kinase; Wnt/beta-catenin; Porcupine | Cytoskeletal Signaling; Metabolism; Stem Cells |
IWP-2 是一种 Wnt 加工和分泌抑制剂,IC50为 27 nM。它还是一种具有 ATP 竞争能力的CK1δ抑制剂,对于M82FCK1δ的IC50为 40 nM。在无细胞试验中,它可选择性阻断 Porcn 介导的 Wnt 棕榈酰化。 | |||
T1877 |
LH846
LH-846,LH 846 |
Casein Kinase | Metabolism; Stem Cells |
LH846 是一种CKIδ的选择性抑制剂,IC50值为 290 nM。它对 CKIα 和 CKIε 的IC50值分别为 2.5 μM 和 1.3 μM。 | |||
T8987 |
Epiblastin A
|
Casein Kinase | Metabolism; Stem Cells |
Epiblastin A 是 ATP 竞争性的酪蛋白激酶 1 (CK1) 抑制剂,能够抑制 CK1α (IC50:8.9 µM)、 CK1δ (IC50:0.5 µM)、CK1 ɛ (IC50:4.7 µM)。它能够抑制 CK1 诱导外胚层干细胞重编程为胚胎干细胞。 | |||
T2440 |
IC261
SU-5607 |
Apoptosis; Casein Kinase; CDK | Apoptosis; Cell Cycle/Checkpoint; Metabolism; Stem Cells |
IC261 (SU-5607) 是一种选择性的,ATP 竞争性的CK1抑制剂,可触发有丝分裂检查点控制。对Ckiδ、Ckiε、 Ckiα1 和Cdk5的IC50值分别为 1 μM、1 μM 、16 μM 和4.5mM。 | |||
T10547 |
BioE-1115
|
Serine/threonin kinase; Casein Kinase | Cell Cycle/Checkpoint; Metabolism; Stem Cells |
BioE-1115 是一种特异性和有效的丝氨酸-苏氨酸蛋白激酶抑制剂 (PASK, IC50 = 4 nM)。 BioE-1115 是一种有效的酪蛋白激酶 2α 抑制剂 (IC50 = 10 μM)。 | |||
T79697 |
Casein kinase 1δ-IN-10
|
Casein Kinase | Metabolism; Stem Cells |
Casein kinase1δ-IN-10为一种针对酪蛋白激酶1δ(CK1δ)的抑制剂。 | |||
T76383 |
Casein Kinase II Receptor Peptide
|
||
Casein KinaseII Receptor Peptid 是酪蛋白激酶 II 的一种底物,Km 值为 500 µM。Casein KinaseII Substrate 可用于测定粗制酶制剂中酪蛋白激酶 II 的活性。 | |||
T76475 |
Casein Kinase II Substrate
|
||
Casein KinaseII Substrate 是一种酪蛋白激酶 II (CK2) 肽底物,可被CK2选择性磷酸化。 | |||
T79127 |
Casein kinase 1δ-IN-4
|
Casein Kinase | Metabolism; Stem Cells |
Casein kinase1δ-IN-4(compound 567)是一种高效的casein kinase1δ抑制剂,展现出在阿尔茨海默病研究中的潜在应用价值。 | |||
T79154 |
Casein kinase 1δ-IN-5
|
Casein Kinase | Metabolism; Stem Cells |
Casein kinase1δ-IN-5为一种高效的蛋白激酶CK-1δ选择性抑制剂,IC50值为47 nM。该化合物在体外展现出神经保护和抗炎效果,具备应用于神经退行性疾病研究的潜力。 | |||
T15024 |
Silmitasertib sodium salt
CX-4945 sodium salt |
Casein Kinase; Autophagy | Autophagy; Metabolism; Stem Cells |
Silmitasertib sodium salt (CX-4945 sodium salt) 是一种可口服的高度选择性 CK2抑制剂,对 CK2α 和 CK2α' 的 IC50值均为 1 nM。 | |||
T6150 |
TAK-715
|
p38 MAPK; Casein Kinase; JNK | MAPK; Metabolism; Stem Cells |
TAK-715 是一种具有口服活性的p38 MAPK 抑制剂,对 p38α 和 p38β 的IC50分别为 7.1 nM 和200 nM。它抑制酪蛋白激酶 I (CK1δ/ε),调节 Wnt/β-catenin 信号传导的激活,有抗炎活性。 | |||
T2259 |
Silmitasertib
CX-4945,5-[(3-氯苯基)氨基]-苯并[C]-2,6-萘啶-8-羧酸 |
Casein Kinase; Autophagy | Autophagy; Metabolism; Stem Cells |
Silmitasertib (CX-4945) 是一种可口服的高度选择性 CK2抑制剂,Ki 为 0.38 nM。 | |||
T76411 |
Casein Kinase 2 Substrate Peptide
|
||
Casein Kinase2 Substrate Peptide 是一种常见的 CK2底物肽。Casein Kinase2 Substrate Peptide 的 C 端与 5-[(2-氨基乙基)氨基]萘-1-磺酸 (EDANS) 结合。Casein Kinase2 Substrate Peptide 可用于蛋白激酶 CK2活性的测定。 | |||
T9356 |
(E/Z)-GO289
|
Casein Kinase | Metabolism; Stem Cells |
(E/Z)-GO289 是一种选择性酪蛋白激酶 2 抑制剂,IC50值为 7 nM。它可显着延长昼夜节律周期,表现出与细胞时钟功能相关的癌细胞生长的细胞类型依赖性抑制。 | |||
T2008 |
LY294002
LY 294002,NSC 697286,SF 1101 |
Apoptosis; DNA-PK; Casein Kinase; PI3K; Autophagy | Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells |
LY294002 (SF 1101) 是一种 PI3K 的广谱抑制剂,抑制 PI3Kα、PI3Kδ 和 PI3Kβ (IC50=0.5/0.57/0.97 μM)。LY294002 也是 DNA-PK 抑制剂 (IC50=1.4 μM) 和 CK2 抑制剂 (IC50=98 nM)。LY294002 可以激活凋亡和自噬。 | |||
T4976 |
Umbralisib
TGR-1202,RP5264,TGR 1202,TGR1202 |
PI3K | PI3K/Akt/mTOR signaling |
Umbralisib (TGR 1202) 是一种PI3Kδ抑制剂,IC50=22.2 nM,EC50=24.3 nM。它同时可抑制CK1ε,EC50=6.0 μM。 | |||
T4079 |
LY-294002 hydrochloride
SF 1101,LY 294002,NSC 697286 |
PI3K | PI3K/Akt/mTOR signaling |
LY-294002 hydrochloride (NSC 697286) 是一种合成的 PI3Kα/δ/β 分子抑制剂(IC50:0.5/0.57/0.97 μM,在无细胞试验中);在溶液中比 Wortmannin 更稳定,也是自噬体形成的阻断剂。 | |||
T19913 |
CKI-7
CKI 7 2HCl,CKI-7 dihydrochloride,N-(2-氨基乙基)-5-氯异喹啉-8-磺酰胺二盐酸盐,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl |
ROCK; SGK; Casein Kinase; CDK; S6 Kinase | Cell Cycle/Checkpoint; Cytoskeletal Signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells |
CKI-7 是一种有效且 ATP 竞争性的酪蛋白激酶 1 抑制剂,IC50为 6 μM,Ki 为 8.5 μM。它选择性抑制 Cdc7激酶,还抑制 SGK,S6K1以及 MSK1。 | |||
T13004 |
SSTC3
|
Casein Kinase; Wnt/beta-catenin | Cytoskeletal Signaling; Metabolism; Stem Cells |
SSTC3 是一种酪蛋白激酶 1α (CK1α) 的激活剂,Kd 为 32 nM。SSTC3 具有潜在的抗肿瘤活性,可抑制 WNT 信号传导,抑制 SHH 髓母细胞瘤肿瘤的生长。 | |||
T7789 |
DRB
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
DRB 是一种核苷类似物,对几种羧基末端结构域激酶(包括酪蛋白激酶 II 、细胞周期依赖性激酶)有抑制作用。它可诱导人类结肠腺癌细胞的 p53 依赖性凋亡,且不会诱发健康细胞遗传毒性应激。 | |||
T6187 |
TDZD-8
GSK-3β Inhibitor I,NP 01139 |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
TDZD-8 (NP 01139) 是抑制GSK-3β的抑制剂,其 IC50=2 μM。它对 Cdk-1/cyclin B,CK-II,PKA 和 PKC 的作用较弱,IC50值均 >100 μM。 | |||
T60005 |
CK1-IN-3
|
Casein Kinase | Metabolism; Stem Cells |
CK1-IN-3 是酪蛋白激酶 1 抑制剂,可用于治疗或预防与 circadiantiazol 节律相关的疾病、炎症性疾病的研究。 | |||
T3689 |
Ruboxistaurin hydrochloride
Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride,芦布妥林 |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Ruboxistaurin hydrochloride (LY 333531 hydrochloride) 是蛋白激酶 C(PKC) 的同工酶选择性抑制剂,竞争性且可逆地抑制 PKCβI 和 PKCβII,IC50 值分别为 4.7 和 5.9 nM。 | |||
T15469 |
Hematein
Hydroxybrasilein |
Wnt/beta-catenin; Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells |
Hematein 抑制Akt/PKB Ser129磷酸化,Wnt/TCF 途径,并增加癌症细胞的凋亡。Hematein 是苏木精的氧化产物,也是变构酪蛋白激酶II 抑制剂(IC50:0.74μM)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2869 |
Emodin
Frangula emodin,大黄素 |
SARS-CoV; Casein Kinase; Autophagy | Autophagy; Metabolism; Microbiology/Virology; Stem Cells |
Emodin (Frangula emodin) 是蒽醌衍生物,有抗SARS-CoV 作用。它阻断 SARS 冠状病毒刺突蛋白和血管紧张素转化酶 2 的相互作用。它抑制酪蛋白激酶 2 ,具有抗炎和抗癌作用。它可改善饮食诱导的肥胖小鼠的代谢紊乱。 | |||
T0465 |
Ellagic acid
鞣花酸,Gallogen,Elagostasine |
Hedgehog/Smoothened; Casein Kinase; Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; PKA; Syk; PKC; Carbonic Anhydrase | Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors |
Ellagic acid (Gallogen) 是从 Eucalyptus maculata Hook 和 E. Hemipholia F. Muell 的 kino 中分离出来的稠合四环天然产物,是一种有效的,ATP 竞争性的CK2抑制剂,IC50和Ki 值分别为 40 nM 和 20 nM。 | |||
TN2019 |
Orobol
3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮 |
BCL; Caspase; PI3K | Apoptosis; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) 是酪氨酸特异性蛋白激酶和磷脂酰肌醇转换的抑制剂。Orobol 抑制 PI3K,对 PI3K α/β/γ/K/δ 的 IC50 为 3.46-5.27 μM。 Orobol 具有抗皮肤老化和抗肥胖的作用。 | |||
T8305 |
Ellagic acid (hydrate)
Ellagic Acid hydrate,鞣花酸水合物 |
Antioxidant; Casein Kinase | Metabolism; oxidation-reduction; Stem Cells |
Ellagic acid (hydrate) 是存在于许多水果和蔬菜中的一种天然抗氧化剂,是 ATP 竞争性的 CK2抑制剂,IC50和 Ki 值分别为 40 nM 和 20 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04750 |
CSNK2A2 Protein, Human, Recombinant
CK2A2,CSNK2A1,casein kinase 2, alpha prime... |
Human | Baculovirus Insect Cells |
CSNK2A2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.4 kDa and the accession number is P19784. | |||
TMPY-04422 |
Casein Kinase 1 gamma 2 Protein, Human, Recombinant (His)
CK1g2,casein kinase 1, γ2,casein ... |
Human | Baculovirus Insect Cells |
Casein kinase I gamma 2 isoform (CSNK1G2), a member of the large casein kinase I (CKI) subfamily, protein kinase superfamily. It may affect the development of brain, and associate with vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. The CKI family includes several other isoforms (alpha, beta, gamma, and delta). Dishevelled (Dsh), another positive component of the Wnt pathway, becomes phosphorylated in response to Wnt signals. All the CKI isoforms, with the exce... | |||
TMPY-04375 |
Casein Kinase 1 alpha Protein, Human, Recombinant (GST)
CKIa,casein kinase 1, alpha 1,casein |
Human | Baculovirus Insect Cells |
Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. High expression of CSNK2A1, or concomitantly high expression of CSNK2A1, are independent prognostic factors of poor survival in NSCLC patients. CSNK2A1 are use... | |||
TMPY-04402 |
CSNK1G1 Protein, Human, Recombinant (His & GST)
CK1γ1,casein kinase 1, gamma 1,casein<... |
Human | Baculovirus Insect Cells |
Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are serine / threonine-selective enzymes that function as regulators ofsignal transductionpathways in most eukaryotic cell types. Casein has been used as a substrate since the earliest days of research on protein phosphorylation. Casein kinase activity associated with the endopla... | |||
TMPY-04758 |
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant
casein kinase 2, α1 polypeptide,casein... |
Mouse | Baculovirus Insect Cells |
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 45.3 kDa and the accession number is Q60737. | |||
TMPY-04441 |
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST)
casein kinase 2, alpha 1 polypeptide,c... |
Mouse | Baculovirus Insect Cells |
CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.9 kDa and the accession number is Q60737. | |||
TMPY-04372 |
CK2 alpha/CSNK2A1 Protein, Human, Recombinant (GST)
CK2 α/CSNK2A1,CKII,CSNK2A3,CK2A1,casein kinase<... |
Human | Baculovirus Insect Cells |
CK2 alpha/CSNK2A1 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 71.4 kDa and the accession number is P68400-1. | |||
TMPY-04393 |
CSNK2A2 Protein, Human, Recombinant (His & GST)
casein kinase 2, alpha prime polypeptide,C... |
Human | Baculovirus Insect Cells |
CSNK2A2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69 kDa and the accession number is P19784. | |||
TMPH-01054 |
CSNK1E Protein, Human, Recombinant (His)
Casein kinase I isoform epsilon,CKI-epsilo... |
Human | E. coli |
CSNK1E Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.3 kDa and the accession number is P49674. | |||
TMPJ-01387 |
PACSIN2 Protein, Human, Recombinant (His)
Protein Kinase C and Casein Kinase |
Human | HEK293 Cells |
Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2 (PACSIN2) is a member of the PACSIN family. PACSIN2 is localized to the plasma membrane via its coiled-coil domain. PACSIN2 is widely expressed and contains one FCH domain and one SH3 domain. PACSIN2 forms homo- and hetero-aggregates with other PACSINs. PACSIN2 may play a role in vesicle formation and transport. In addition, PACSIN2 is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymeri... | |||
TMPJ-01307 |
PACSIN1 Protein, Human, Recombinant (His)
Protein Kinase C and Casein Kinase |
Human | HEK293 Cells |
Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in the heart, pancreas, and liver. PACSIN1 may play a role in vesicle formation and transport. PACSIN1 has been shown to interact with DNM1, PACSIN3, Huntingtin, and PACSIN2. In addition, PACSIN1 is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). | |||
TMPH-02647 |
FAM20C Protein, Mouse, Recombinant (His & Myc)
Fam20c,Dentin matrix protein 4,Golgi-enriched fraction c... |
Mouse | Baculovirus Insect Cells |
FAM20C Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 60.4 kDa and the accession number is Q5MJS3. | |||
TMPJ-01261 |
PPP1R14A Protein, Human, Recombinant (His)
17 kDa PKC-Potentiated Inhibitory Protein of PP1,CPI17,PPP1R... |
Human | E. coli |
Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA su... | |||
TMPJ-01068 |
FKBP25/FKBP3 Protein, Human, Recombinant (His)
25 kDa FKBP,FKBP-3,Peptidyl-prolyl cis-trans isomerase FKBP3... |
Human | E. coli |
FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a... | |||
TMPJ-01190 |
SPESP1 Protein, Human, Recombinant (His)
Sperm Equatorial Segment Protein 1,Glycosylated 38 kDa Sperm... |
Human | HEK293 Cells |
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may intera... | |||
TMPY-04137 |
ATP6V1F Protein, Human, Recombinant (GST)
Vma7,ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F,... |
Human | E. coli |
ATP6V1F encodes a component of vacuolar ATPase mediating acidification. The cDNA and the genomic sequences of ATP6V1F were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) using reverse transcription polymerase chain reaction and touchdown-polymerase chain reaction, respectively. Topology prediction showed that there is one protein kinase C phosphorylation site, two Casein kinase II phosphorylation sites, and one N-myristoylation site in the ATP6V1F protein. U... | |||
TMPY-01948 |
COQ7 Protein, Human, Recombinant (His)
CLK1,coenzyme Q7 homolog, ubiquinone (yeast),CAT5,CLK-1 |
Human | HEK293 Cells |
Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. Th... | |||
TMPJ-00991 |
S100A8 Protein, Rat, Recombinant (His)
Leukocyte L1 complex light chain,Migration inhibitory factor... |
Rat | E. coli |
Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhi... | |||
TMPY-03438 |
Calsequestrin 1 Protein, Human, Recombinant
CASQ,PDIB1,VMCQA,calsequestrin 1 (fast-twitch, skeletal musc... |
Human | E. coli |
Calsequestrin-1 is an isoform of calsequestrin. Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. It helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. Two forms of calsequestrin have been identified: Calsequestrin-2 and Calsequestrin-1. Calsequestrin-1 is found in fast skeletal muscle. The release of calsequestrin-boun... |