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Search Results for " carbonic anhydrase "

Targets Recommended: Carbonic Anhydrase Others

129

抑制剂 & 化合物

8

天然产物

38

重组蛋白

6

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T76013	Carbonic anhydrase	Others	Others
	Carbonic anhydrase 是原核生物和真核生物中普遍存在的含锌金属酶。Carbonic anhydrase 可以催化二氧化碳可逆地转化为碳酸氢盐和质子。Carbonic anhydrase 可用于癌症、青光眼、肥胖症和癫痫症的研究。
T77631	Enpp/Carbonic anhydrase-IN-2	Apoptosis; PDE; Carbonic Anhydrase	Apoptosis; Metabolism
	Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-IN-2 induced apoptosis.Enpp/Carbonic anhydrase-IN-2 has antiproliferative activity against cancer cells and low cytotoxicity against normal cells.
T67775	Enpp/Carbonic anhydrase-IN-1	PDE; Carbonic Anhydrase	Metabolism
	Enpp/Carbonic anhydrase-IN-1 (compound 1e) 是有效的 Enpp 和 carbonic anhydrase 抑制剂。Enpp/Carbonic anhydrase-IN-1抑制 NPP1、NPP2、NPP3、CA-II、CA-IX 的 IC50 值分别 1.36、1.35、3.00、0.88、1.02 µM。Enpp/Carbonic anhydrase-IN-1 选择性抑制癌细胞的增殖，对正常细胞毒性较低。
T63305	Carbonic anhydrase inhibitor 6	Carbonic Anhydrase	Metabolism
	Carbonic anhydrase inhibitor 6 是一种高效的人碳酸酐酶 (hCA) 抑制剂，抑制 hCA IX，hCA II，hCA XII和hCA I，可用于研究碳酸酐酶异常引起的疾病。
T0515	Tioxolone	Carbonic Anhydrase	Metabolism
	Tioxolone 是一种金属酶碳酸酐酶 I 抑制剂，具有抗痤疮作用。
T16960	Sultiame	Others; Carbonic Anhydrase	Metabolism; Others
	Sultiame 是一种碳酸酐酶抑制剂。 Sultiame 可用于抗癫痫研究。
T8827	EMAC10101d	Carbonic Anhydrase	Metabolism
	EMAC10101d 是 hCA II 选择性抑制剂(Ki:8.1 nM)。
T0142	Brinzolamide 布林佐胺,AL-4862	Carbonic Anhydrase	Metabolism
	Brinzolamide (AL-4862) 是一种碳酸酐酶(carbonic anhydrase)II 抑制剂(IC50:3.19 nM)。
T0782	Benzthiazide Aquatag,苄噻嗪,Lemazide,Dihydrex	Carbonic Anhydrase	Metabolism
	Benzthiazide (Lemazide) 是长效利尿剂及抗高血压剂。它也是碳酸酐酶 9 的抑制剂，他对 CA9，CA2 和 CA1 的 Ki 分别为 8.0，8.8 和 10 nM。它对肿瘤细胞增殖具有抑制作用。
T6781	Benzenesulfonamide Benzenesulphonamide,苯磺酰胺,Phenyl sulfonamide,Benzosulfonamide	Carbonic Anhydrase	Metabolism
	Benzenesulfonamide (Benzosulfonamide) 是碳酸酐酶的抑制剂。
T4321	Indisulam E 7070	CDK; Carbonic Anhydrase	Cell Cycle/Checkpoint; Metabolism
	Indisulam (E 7070) 是碳酸酐酶抑制剂。它是细胞周期 G1期的靶向化合物，能够抑制 CDK2及周期蛋白 E 的激活，阻止 G1/S 的转化。它可以募集 DCAF15诱导RBM39降解来靶向剪接，具有抗癌作用。
T2187	Orthanilamide O-Aminobenzenesulfonamide,邻氨基苯磺酰胺,Benzenesulfonamide,O-Sulfanilamide	Carbonic Anhydrase; Autophagy	Autophagy; Metabolism
	Orthanilamide (Orthanilamide) 是一种碳酸酐酶 IX 抑制剂。
T6581	Methyclothiazide Duretic,Enduron,甲氯噻嗪,Aquatensen	Others; Carbonic Anhydrase	Metabolism; Others
	Methyclothiazide (Aquatensen) 是一种具有口服活性的利尿剂，也是一种降压剂。它能够拮抗体外的电压依赖性钙通道的 (VDCC) 活性，也可以抑制内源性血管收缩刺激导致的血管反应。
T6469	Dichlorphenamide Diclofenamide,双氯非那胺,二氯苯二磺胺,Daranide,Antidrasi	Carbonic Anhydrase	Metabolism
	Dichlorphenamide (Diclofenamide) 是一种碳酸酐酶抑制剂。
T83137	ALP/Carbonic anhydrase-IN-1	Carbonic Anhydrase	Metabolism
	ALP/Carbonic anhydrase-IN-1（Compound 1e）为碳酸酐酶（CA）与碱性磷酸酶（ALP）的双效抑制剂。对CA-II、CA-IX、CA-XII和ALP具有显著抑制活性，其IC50值分别为0.44 µM、1.61 µM、0.51 µM和0.107 µM。
T36758	CAIX Inhibitor S4 S4	Carbonic Anhydrase	Metabolism
	CAIX Inhibitor S4 (S4) 是一种有效的碳酸酐酶 IX/XII 抑制剂，Ki 分别为 7 nM 和 2 nM。 CA II 和 CA I 的 Ki 分别为 546 和 5600 nM。
T61120	Carbonic anhydrase inhibitor 2	Others	Others
	Carbonic Anhydrase Inhibitor2 (compound 7c) 是一种针对 Carbonic Anhydrase II 抑制剂，有效降低青光眼兔眼压。
T61980	Carbonic anhydrase inhibitor 8	Others	Others
	Carbonic anhydrase inhibitor 8 (compound R-13) 是一种有效的人碳酸酐酶 (hCA) 抑制剂。Carbonic anhydrase inhibitor 8抑制 hCA I、hCA II、hCA IV 的Ki 值分别为 60.7 nM、320.7 nM、2298 nM。
T62666	Carbonic anhydrase inhibitor 7	Others	Others
	Carbonic anhydrase inhibitor 7 是一种人碳酸酐酶 (hCA) 的有效抑制剂，作用于 hCA IX (Ki: 6.5 nM)，hCA II (Ki: 7.1 nM)，hCA XII (Ki: 72.1 nM) 和 hCA I (Ki: 255.8 nM)。
T78840	Carbonic anhydrase inhibitor 15	Carbonic Anhydrase	Metabolism
	Carbonic anhydrase inhibitor15 (Compound 8) 是具有Ki值为8.5 nM对hCA II的碳酸酐酶抑制剂，同时展现出镇痛效应。
T5012	Ethoxzolamide 依索唑胺,PNU-4191,Redupresin,L-643786	Antibacterial; Carbonic Anhydrase	Metabolism; Microbiology/Virology
	Ethoxzolamide (L-643786) 对 carbonic anhydrase 有抑制作用，Ki 值为 1 nM。
T21294	Polmacoxib CG-100649,帕马考昔,CG100649,CG 100649	COX; Carbonic Anhydrase	Immunology/Inflammation; Metabolism; Neuroscience
	Polmacoxib (CG 100649) 是一流的 NSAID 候选药物，是碳酸酐酶 (CA) 和 COX-2 的双重抑制剂。它在小鼠模型中抑制大肠腺瘤和肿瘤生长。
T63731	Carbonic anhydrase inhibitor 9	Others	Others
	Carbonic anhydrase inhibitor 9 是碳酸酐酶 (CA) 的有效抑制剂，能够作用于 hCA II (Ki: 56.4 nM) 和 IX (Ki: 56.9 nM)，表现出抗增殖效果。
T63005	Carbonic anhydrase inhibitor 11	Others	Others
	Carbonic anhydrase inhibitor 11 (compound VI) 是一种有效的、选择性碳酸酐酶抑制剂，能够作用于 CA II (Ki: 40 nM)、CA IX (Ki: 39 nM) 和 CA XII (Ki: 900 nM)。
T72164	Enpp/Carbonic anhydrase-IN-2	Others	Others
	Enpp/Carbonic anhydrase-IN-2 是一种有效的 Enpp 和 carbonic anhydrase 抑制剂，对 NPP1、NPP2、NPP3、CA-IX, CA-XII 的 IC50值分别 1.13、 1.07、 0.74、 0.33、 0.68。Enpp/Carbonic anhydrase-IN-2 对癌细胞具有抗增殖活性，对正常细胞具有低细胞毒性。Enpp/Carbonic anhydrase-IN-2 诱导细胞凋亡 (Apoptosis)。
T0106	Methazolamide L584601,醋甲唑胺,CL 8490	Carbonic Anhydrase	Metabolism
	Methazolamide (CL 8490) 是一种磺胺衍生物，用作碳酸酐酶 (carbonic anhydrase) 抑制剂，对人 carbonic anhydrase II 的 Ki=为 14 nM。它是降低眼压的药物，能够抑制由青光眼及其他眼病引起的眼压升高的作用。
T61952	Carbonic anhydrase inhibitor 13	Others	Others
	Carbonic anhydrase inhibitor 13 (化合物 7) 是有效的碳酸酐酶 (CA) 抑制剂。
T61829	Carbonic anhydrase inhibitor 4	Others	Others
	Carbonic anhydrase inhibitor 4 is a photoprobe that inhibits the activity of carbonic anhydrase. It specifically targets human carbonic anhydrases, including hCA I-XIV, with K i values ranging from 640-1166 nM [1].
T60848	Carbonic anhydrase inhibitor 3	Others	Others
	Carbonic anhydrase inhibitor 3 (compound 11g) 可降低青光眼兔的眼压，它是一种碳酸酐酶 II 的抑制剂，。
T62976	Carbonic anhydrase inhibitor 5	Others	Others
	Carbonic anhydrase inhibitor 5 是一种有效的、选择性的人碳酸酐酶 (hCA) 抑制剂，能够作用于 hCA II (IC50: 42.9 nM)、hCA IX (IC50: 47.6 nM) 和 hCA XII (IC50: 6.7 nM)。
T61032	Carbonic anhydrase inhibitor 10	Others	Others
	Carbonic anhydrase inhibitor 10 可用于研究癌症，它对 MCF-7 癌细胞表现出抗增殖活性， IC50值为 11.9 μM。Carbonic anhydrase inhibitor 10 是 hCA IX 的有效抑制剂，Ki 值为 6.2 nM。
T61842	Carbonic anhydrase inhibitor 14	Others	Others
	Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibits CDK2 with an IC 50 of 20.3 μM. Furthermore, Carbonic anhydrase inhibitor 14 demonstrates significant antitumor activity [1].
T72122	Carbonic anhydrase inhibitor 12	Carbonic Anhydrase	Metabolism
	碳酸酐酶抑制剂12是针对CA II具有高效抑制作用的化合物，其Kis值仅为1.72 nM，对CA I亦表现出有效抑制（Kis为271 nM）。此外，该化合物在多种肿瘤细胞系中显示出显著的抗癌活性。
T2017	U-104 NSC-213841,MST-104	Carbonic Anhydrase	Metabolism
	U-104 (NSC-213841) 是 CA IX 和 CA XII 碳酸酐酶 (CA) 抑制剂，其 Ki 分别为 45.1 nM 和 4.5 nM。小鼠模型中，它能够表现出明显的抑制肿瘤生长的作用。
T0267	Zonisamide AD 810,唑尼沙胺,CI 912	Calcium Channel; Sodium Channel; Carbonic Anhydrase	Membrane transporter/Ion channel; Metabolism
	Zonisamide (AD 810) 是锌酶碳酸酐酶 (carbonic anhydrase) 的有效抑制剂，对人类线粒体同工酶 hCA II 和 hCA V 作用的 Ki 值分别为 35.2 nM 和 20.6 nM。Zonisamide 具有抗癫痫活性，在癫痫、癫痫发作和帕金森病的研究中具有价值。
T61982	Human carbonic anhydrase II-IN-2	Others	Others
	Human carbonic anhydrase II-IN-24 (Compound R-13) 是一种有效的人碳酸酐酶(hCA)抑制剂。Human carbonic anhydrase II-IN-24抑制 hCA I、II、IV 和 IX 的 Ki 分别为 60.7、320.7 和 2298 和 35.2 nM。
T23782	Benzolamide CL-11366,W 1803,CL 11366,CL11366,苯唑拉胺,W-1803	Carbonic Anhydrase	Metabolism
	Benzolamide (CL 11366) 是碳酸酐酶 (CA) 抑制剂，抑制hCA I(Ki:15 nM)、hCA II(Ki:9 nM)、EcoCAγ(Ki:94 nM)、VchCAγ(Ki:78 nM)、CAS3(Ki:54 nM)。它可用于研究青光眼和癫痫。
T61981	Human carbonic anhydrase II-IN-1	Others	Others
	Human carbonic anhydrase II-IN-1 (Compound S-13) 是一种有效的人碳酸酐酶 II (hCA II) 抑制剂。Human carbonic anhydrase II-IN-1抑制 hCA II，其他 hCA 同工型 I、IV 和 IX 的分别 Ki 为 4.4 nM、 9.2 nM、480.2 nM 和 14.7 nM。Human carbonic anhydrase II-IN-1可用于青光眼的研究。
T6503	Fluorometholone Acetate NSC 47438,Flarex,Eflone,氟米龙醋酸酯,Oxylone acetate	Glucocorticoid Receptor; Carbonic Anhydrase	Endocrinology/Hormones; Metabolism
	Fluorometholone Acetate (Oxylone acetate) 是合成的糖皮质激素皮质类固醇及皮质类固醇酯。它有效抑制碳酸酐酶 (CA) 对 hCA-I(IC50:2.18 μM)和 hCA-II(IC50:17.5 μM)。它具有抗炎活性，可用于研究外部眼部炎症。
T0037	Halazone 哈拉宗,Cloritines,Pantocid,Halazon	Sodium Channel; Antibacterial; Antibiotic; Carbonic Anhydrase	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Halazone (Pantocid) 是一种非典型的磺酰胺衍生物，有抗菌活性。它也是碳酸酐酶 II 抑制剂，Kd 值为 1.45 µM。它广泛用于饮用水消毒，可保护钠通道免于灭活。
T0675	Topiramate RWJ 17021,McN 4853,托吡酯	Potassium Channel; Calcium Channel; GABA Receptor; Sodium Channel; GluR; Carbonic Anhydrase; iGluR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Topiramate (RWJ 17021) 是一种GluR5受体拮抗剂，可通过增强GABAergic 活性，抑制kainate/AMPA 受体，抑制钠和钙通道的电压敏感，增加钾电导并抑制碳酸酐酶来产生抗癫痫作用，用于治疗部分性和全身性癫痫发作。
T2134	Dorzolamide hydrochloride MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl	Carbonic Anhydrase	Metabolism
	Dorzolamide hydrochloride (MK507 hydrochloride) 是一种碳酸酐酶carbonic anhydrase II 抑制剂，能够抑制红细胞CA-II(IC50:0.18 nM) 和CA-I(IC50:600 nM) 。
T34994	Uk-390957 Uk390957,Uk 390957	Others	Others
	Uk-390957 是一种磺酰胺化合物，由于与碳酸酐酶结合而具有高BPR。
T8611	2,3-dihydro-1H-indene-5-sulfonamide	Carbonic Anhydrase	Metabolism
	2,3-dihydro-1H-indene-5-sulfonamide 是碳酸酐酶 12（人）抑制剂。
T60561	Disulfamide	Carbonic Anhydrase	Metabolism
	Disulfamide 是一种具有口服活性的碳酸酐酶 (carbonic anhydrase) 抑制剂，其 IC50 值为 0.07 μM。Disulfamide 具有利尿作用，可通过抑制碳酸酐酶，阻止钠、碳酸氢盐在近曲小管中的重吸收，从而发挥作用。
T68136	(Iso)-Samixogrel	COX; Carbonic Anhydrase	Immunology/Inflammation; Metabolism; Neuroscience
	(Iso)-Samixogrel对碳酸酐酶和环加氧酶 2 有活性。
T34093	pNNP p NNP,p-Nitrophenyl phosphate,p-NNP,Nitrophenylphosphate	Carbonic Anhydrase	Metabolism
	pNNP (Nitrophenylphosphate) 可用作 PP2C 试验的底物。pNNP 对β-碳酸酐酶和α-碳酸酯脱水酶有抑制作用，对幽门螺杆菌幽门螺杆菌也具有抑制作用。pNNP 是一种活性较弱的组织非特异性碱性磷酸酶调节剂。
T80663	hCAI/II/IV-IN-28 WAY-638358	Carbonic Anhydrase	Metabolism
	hCAI/II/IV-IN-28(WAY-638358) 是一种有效的碳酸酐酶抑制剂，具有潜在抗惊厥活性。
T67774	Compound CDy9	Carbonic Anhydrase	Metabolism
	Compound CDy9 是碳酸酐酶（CA）的高选择性抑制剂，对hCA II 的IC50值为0.18μM。
T76684	Girentuximab cG250,WX-G250,G250	Carbonic Anhydrase	Metabolism
	Girentuximab (G250) 是一种有效的抗碳酸酐酶 IX (CAIX)单克隆抗体，具有抗癌活性，可用于研究尿路上皮癌 PET (ZiPUP）。

化合物

Carbonic anhydrase

Cat.No: T76013

Target: Others

Enpp/Carbonic anhydrase-IN-2

Cat.No: T77631

Target: Apoptosis, PDE, Carbonic Anhydrase

Enpp/Carbonic anhydrase-IN-1

Cat.No: T67775

Target: PDE, Carbonic Anhydrase

Carbonic anhydrase inhibitor 6

Cat.No: T63305

Target: Carbonic Anhydrase

Cat.No: T0515

Target: Carbonic Anhydrase

Cat.No: T16960

Target: Others, Carbonic Anhydrase

Cat.No: T8827

Target: Carbonic Anhydrase

Cat.No: T0142

Synonym: 布林佐胺,AL-4862

Target: Carbonic Anhydrase

Cat.No: T0782

Synonym: Aquatag,苄噻嗪,Lemazide,Dihydrex

Target: Carbonic Anhydrase

Benzenesulfonamide

Cat.No: T6781

Synonym: Benzenesulphonamide,苯磺酰胺,Phenyl sulfonamide,Benzosulfonamide

Target: Carbonic Anhydrase

Cat.No: T4321

Synonym: E 7070

Target: CDK, Carbonic Anhydrase

Cat.No: T2187

Synonym: O-Aminobenzenesulfonamide,邻氨基苯磺酰胺,Benzenesulfonamide,O-Sulfanilamide

Target: Carbonic Anhydrase, Autophagy

Methyclothiazide

Cat.No: T6581

Synonym: Duretic,Enduron,甲氯噻嗪,Aquatensen

Target: Others, Carbonic Anhydrase

Dichlorphenamide

Cat.No: T6469

Synonym: Diclofenamide,双氯非那胺,二氯苯二磺胺,Daranide,Antidrasi

Target: Carbonic Anhydrase

ALP/Carbonic anhydrase-IN-1

Cat.No: T83137

Target: Carbonic Anhydrase

CAIX Inhibitor S4

Cat.No: T36758

Synonym: S4

Target: Carbonic Anhydrase

Carbonic anhydrase inhibitor 2

Cat.No: T61120

Target: Others

Carbonic anhydrase inhibitor 8

Cat.No: T61980

Target: Others

Carbonic anhydrase inhibitor 7

Cat.No: T62666

Target: Others

Carbonic anhydrase inhibitor 15

Cat.No: T78840

Target: Carbonic Anhydrase

Cat.No: T5012

Synonym: 依索唑胺,PNU-4191,Redupresin,L-643786

Target: Antibacterial, Carbonic Anhydrase

Cat.No: T21294

Synonym: CG-100649,帕马考昔,CG100649,CG 100649

Target: COX, Carbonic Anhydrase

Carbonic anhydrase inhibitor 9

Cat.No: T63731

Target: Others

Carbonic anhydrase inhibitor 11

Cat.No: T63005

Target: Others

Enpp/Carbonic anhydrase-IN-2

Cat.No: T72164

Target: Others

Cat.No: T0106

Synonym: L584601,醋甲唑胺,CL 8490

Target: Carbonic Anhydrase

Carbonic anhydrase inhibitor 13

Cat.No: T61952

Target: Others

Carbonic anhydrase inhibitor 4

Cat.No: T61829

Target: Others

Carbonic anhydrase inhibitor 3

Cat.No: T60848

Target: Others

Carbonic anhydrase inhibitor 5

Cat.No: T62976

Target: Others

Carbonic anhydrase inhibitor 10

Cat.No: T61032

Target: Others

Carbonic anhydrase inhibitor 14

Cat.No: T61842

Target: Others

Carbonic anhydrase inhibitor 12

Cat.No: T72122

Target: Carbonic Anhydrase

Cat.No: T2017

Synonym: NSC-213841,MST-104

Target: Carbonic Anhydrase

Cat.No: T0267

Synonym: AD 810,唑尼沙胺,CI 912

Target: Calcium Channel, Sodium Channel, Carbonic Anhydrase

Human carbonic anhydrase II-IN-2

Cat.No: T61982

Target: Others

Cat.No: T23782

Synonym: CL-11366,W 1803,CL 11366,CL11366,苯唑拉胺,W-1803

Target: Carbonic Anhydrase

Human carbonic anhydrase II-IN-1

Cat.No: T61981

Target: Others

Fluorometholone Acetate

Cat.No: T6503

Synonym: NSC 47438,Flarex,Eflone,氟米龙醋酸酯,Oxylone acetate

Target: Glucocorticoid Receptor, Carbonic Anhydrase

Cat.No: T0037

Synonym: 哈拉宗,Cloritines,Pantocid,Halazon

Target: Sodium Channel, Antibacterial, Antibiotic, Carbonic Anhydrase

Cat.No: T0675

Synonym: RWJ 17021,McN 4853,托吡酯

Target: Potassium Channel, Calcium Channel, GABA Receptor, Sodium Channel, GluR, Carbonic Anhydrase, iGluR

Dorzolamide hydrochloride

Cat.No: T2134

Synonym: MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl

Target: Carbonic Anhydrase

Cat.No: T34994

Synonym: Uk390957,Uk 390957

Target: Others

2,3-dihydro-1H-indene-5-sulfonamide

Cat.No: T8611

Target: Carbonic Anhydrase

Cat.No: T60561

Target: Carbonic Anhydrase

(Iso)-Samixogrel

Cat.No: T68136

Target: COX, Carbonic Anhydrase

Cat.No: T34093

Synonym: p NNP,p-Nitrophenyl phosphate,p-NNP,Nitrophenylphosphate

Target: Carbonic Anhydrase

hCAI/II/IV-IN-28

Cat.No: T80663

Synonym: WAY-638358

Target: Carbonic Anhydrase

Cat.No: T67774

Target: Carbonic Anhydrase

Cat.No: T76684

Synonym: cG250,WX-G250,G250

Target: Carbonic Anhydrase

Cat. No.	Product Name	Target	Signaling Pathways
T4S2354	Dimethylfraxetin 二甲基白蜡树亭,Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin	Carbonic Anhydrase	Metabolism
	Dimethylfraxetin (6,7,8-Trimethoxycoumarin) 是Carbonic anhydrase 抑制剂(Ki:0.0097 μM)。
TN6708	ETHYL 3,5-DIHYDROXYBENZOATE	Others	Others
	ETHYL 3,5-DIHYDROXYBENZOATE 是一种天然产物，抑制人体碳酸酐酶2。
T6S0221	Eriocitrin eriodictyol 7-rutinoside,圣草次甙,Eriodictyol-7-O-Rutinoside,Eriodictioside,圣草次甙；圣草次苷,Eriodictyol glycoside	Apoptosis; Carbonic Anhydrase	Apoptosis; Metabolism
	Eriocitrin (Eriodictyol-7-O-Rutinoside) 是从柠檬中分离出来的一种黄酮类天然产物，是强效的抗氧化剂。它通过激活线粒体涉及的内在信号传导途径来触发细胞凋亡。它通过上调 p53、cyclin A、cyclin D3 和 CDK6 使 S 期细胞周期停滞，从而抑制肝癌细胞的增殖。
T69833	Xanthalin	Others	Others
	Xanthalin is a non-alkaloid natural compound of Angelica purpurascens (Avé-Lall.) Gilli. (Apiaceae) with cholinesterase and carbonic anhydrase inhibition potential.
TN2095	Pomiferin	NOS; NF-κB; PDE	Immunology/Inflammation; Metabolism; NF-κB
	Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has anti-inflammatory and neuroprotective activities.
TN3058	4-O-Methylgrifolic acid	Others	Others
	4-O-Methylgrifolic acid is a natural carbonic anhydrase Ⅱ(CAⅡ) inhibitor, it shows in-hibitory activities against CAⅡ with IC50s in the range of 6.37-71.73 umol/L.
T40611	(E)-Dehydrodiconiferyl alcohol	Others	Others
	(E)-Dehydrodiconiferyl alcohol is a potent dual inhibitor of hCA IX and hCA XII, effectively impeding the catalytic activity of both carbonic anhydrase isoforms. Additionally, (E)-Dehydrodiconiferyl alcohol exerts inhibitory effects on the nuclear translocation of NF-κB in the connective tissue of the healing area.
TN4167	Grifolic acid	Antifection	Microbiology/Virology
	Grifolic acid is a natural carbonic anhydrase Ⅱ inhibitor(CAⅡ), it shows in-hibitory activities against CAⅡ with IC50 of 6.37 umol/L. Grifolic acid has antibacterial activity, it can inhibit the growth of Staphylococcus aureus and Staphylococcus epidermid

天然产物

Dimethylfraxetin

Cat.No: T4S2354

Synonym: 二甲基白蜡树亭,Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin

Target: Carbonic Anhydrase

ETHYL 3,5-DIHYDROXYBENZOATE

Cat.No: TN6708

Target: Others

Cat.No: T6S0221

Synonym: eriodictyol 7-rutinoside,圣草次甙,Eriodictyol-7-O-Rutinoside,Eriodictioside,圣草次甙；圣草次苷,Eriodictyol glycoside

Target: Apoptosis, Carbonic Anhydrase

Cat.No: T69833

Target: Others

Cat.No: TN2095

Target: NOS, NF-κB, PDE

4-O-Methylgrifolic acid

Cat.No: TN3058

Target: Others

(E)-Dehydrodiconiferyl alcohol

Cat.No: T40611

Target: Others

Cat.No: TN4167

Target: Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00690	Carbonic Anhydrase 9 Protein, Human, Recombinant (His) Carbonic Anhydrase IX,MN,CAIX	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.5 kDa and the accession number is A0A0S2Z3D0.
TMPY-00689	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) CAIX,Carbonic Anhydrase IX,MN	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.7 kDa and the accession number is A0A0S2Z3D0.
TMPY-00694	Carbonic Anhydrase 12 Protein, Human, Recombinant (His) HsT18816,FLJ20151,carbonic anhydrase XII,C...	Human	HEK293 Cells
	Carbonic Anhydrase 12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is O43570-1.
TMPY-01735	Carbonic Anhydrase 2 Protein, Human, Recombinant (His) HEL-S-282,CA-II,HEL-76,CAII,carbonic anhydrase<...	Human	E. coli
	Carbonic Anhydrase 2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30 kDa and the accession number is P00918.
TMPY-02990	Carbonic Anhydrase 9 Protein, Canine, Recombinant (His) carbonic anhydrase IX	Canine	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.1 kDa and the accession number is A0A8C0RHE4.
TMPY-01700	Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His) carbonic anhydrase IX	Mouse	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is Q3UUZ9.
TMPJ-00731	Carbonic Anhydrase 1 Protein, Human, Recombinant (His) Carbonic Anhydrase B,Carbonate Dehydratase...	Human	E. coli
	Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonam...
TMPY-02989	Carbonic Anhydrase 9 Protein, Canine, Recombinant (hFc) carbonic anhydrase IX	Canine	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.6 kDa.
TMPY-00691	Carbonic Anhydrase 14 Protein, Mouse, Recombinant (His) Ca14,carbonic anhydrase XIV,Catm,Car14	Mouse	HEK293 Cells
	Carbonic Anhydrase 14 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is Q9WVT6.
TMPY-01761	Carbonic Anhydrase 3 Protein, Human, Recombinant (His) carbonic anhydrase III,CAIII,Car3	Human	E. coli
	Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Carbonic anhydrases (CAs) form a family of enzymes that catalyze the rapid conversion of carbon dioxide and water to bicarbonate an...
TMPY-02133	Carbonic Anhydrase VB Protein, Human, Recombinant (His) carbonic anhydrase VB, mitochondrial,CA-VB...	Human	E. coli
	Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological process...
TMPY-02277	Carbonic Anhydrase 7 Protein, Human, Recombinant (His) CAVII,carbonic anhydrase VII	Human	E. coli
	Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, ...
TMPY-06939	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc & Avi), Biotinylated MN,CAIX,Carbonic Anhydrase IX	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 69.51 kDa and the accession number is NP_001207.2.
TMPH-03259	Carbonic Anhydrase 2 Protein, Rat, Recombinant (His) CA-II,Carbonate dehydratase II,Carbonic anhydra...	Rat	E. coli
	Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. Carbonic Anhydrase 2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.7 kDa and the accession number is P27139.
TMPY-02301	Carbonic Anhydrase 8 Protein, Mouse, Recombinant (His) RP23-180H12.1,Ca8,AW546993,Cals,Carp,carbonic a...	Mouse	E. coli
	Carbonic Anhydrase 8 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P28651.
TMPY-06936	Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated Carbonic Anhydrase IX,CAIX,MN	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 44.23 kDa and the accession number is NP_001207.2.
TMPY-00513	Carbonic Anhydrase 4 Protein, Human, Recombinant (His) CAIV,Car4,RP17,carbonic anhydrase IV	Human	CHO Cells
	Carbonic Anhydrase 4 Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 31.7 kDa and the accession number is P22748-1.
TMPY-00693	Carbonic Anhydrase 10 Protein, Human, Recombinant carbonic anhydrase X,CARPX,CA-RPX,HUCEP-15...	Human	HEK293 Cells
	Carbonic Anhydrase 10 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.2 kDa and the accession number is A0A384MTY8.
TMPY-00967	Carbonic Anhydrase 14 Protein, Human, Recombinant (His) CAXiV,CA14,carbonic anhydrase XIV	Human	HEK293 Cells
	Carbonic Anhydrase 14 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is A8K3J4.
TMPY-00688	Carbonic Anhydrase 12 Protein, Mouse, Recombinant (His) AI314958,Car12,2310047E01Rik,carbonic anhydrase...	Mouse	HEK293 Cells
	Carbonic Anhydrase 12 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q8CI85.
TMPK-00478	Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His) CA12,CAXII,Carbonic anhydrase,CA-XII,Tumor...	Cynomolgus	HEK293 Cells
	Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Carbonic anhydrase XII (CA XII) is a key mediator of several signaling pathways that are involved in cancer development.
TMPH-03258	Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) Cyanamide hydratase CA1,CA-I,Carbonate dehydratase I,Car1,Ca...	Rat	E. coli
	Reversible hydration of carbon dioxide. Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.2 kDa and the accession number is B0BNN3.
TMPY-02302	Carbonic Anhydrase 10 Protein, Mouse, Recombinant (His) carbonic anhydrase X,BB085816,RP23-448I9.1...	Mouse	HEK293 Cells
	Carbonic Anhydrase 10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is P61215.
TMPY-02111	Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His) Car-2,Lvtw-5,Ca2,Ltw-5,carbonic anhydrase ...	Mouse	E. coli
	Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.4 kDa and the accession number is AAH55291.1.
TMPY-01327	Carbonic Anhydrase 4 Protein, Mouse, Recombinant (His) RP23-167D6.1,carbonic anhydrase IV,AW45671...	Mouse	HEK293 Cells
	Carbonic Anhydrase 4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is Q64444.
TMPY-01706	Carbonic Anhydrase 8 Protein, Human, Recombinant (His) CAMRQ3,carbonic anhydrase VIII,MGC120502,C...	Human	E. coli
	Carbonic Anhydrase 8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 33.8 kDa and the accession number is P35219.
TMPY-01351	Carbonic Anhydrase 10 Protein, Human, Recombinant (His) carbonic anhydrase X,CA-RPX,CARPX,CA10,HUC...	Human	HEK293 Cells
	Carbonic Anhydrase 10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is A0A384MTY8.
TMPJ-00701	Carbonic Anhydrase 11 Protein, Human, Recombinant (His) Carbonic Anhydrase-Related Protein 2,CARP ...	Human	HEK293 Cells
	Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA11 is expressed abundantly in the brain with moder...
TMPY-06944	Carbonic Anhydrase 12 Protein, Human, Recombinant (His & Avi), Biotinylated HsT18816,carbonic anhydrase XII,CAXII,FLJ2...	Human	HEK293 Cells
	Carbonic Anhydrase 12 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 33.45 kDa and the accession number is NP_001209.1.
TMPJ-00283	Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated G250,P54/58N,Carbonic Anhydrase IX,CA9,Car...	Human	HEK293 Cells
	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC...
TMPH-01038	CA5A Protein, Human, Recombinant Carbonic anhydrase VA,Carbonic	Human	HEK293 Cells
	Reversible hydration of carbon dioxide. Low activity. CA5A Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 30.6 kDa and the accession number is P35218.
TMPY-01877	CA5A Protein, Human, Recombinant (His) CA5,GS1-21A4.1,CA5AD,carbonic anhydrase VA...	Human	E. coli
	Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospi...
TMPK-01252	E8L Protein, Monkeypox virus, Recombinant (His) Cell surface-binding protein,Carbonic anhydrase...	Monkeypox virus	E. coli
	E8L is an important protein that mediates the invasion of monkeypox virus into host cells. In the process of invading and completing replication, E8L acts as a surface-binding protein of mature virion and can bind to chondroitin sulfate on the cell surface, so that the virus can attach to target cells.
TMPY-01734	CA13 Protein, Human, Recombinant (His) carbonic anhydrase XIII,FLJ37995,CAXIII,MG...	Human	E. coli
	The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. The CAXIII is a member of th...
TMPH-03655	Vaccinia virus (strain Copenhagen) OPG105 Protein (His & SUMO) OPG105,Carbonic anhydrase homolog,Cell sur...	VACV	E. coli
	Binds to chondroitin sulfate on the cell surface to provide virion attachment to target cell. Vaccinia virus (strain Copenhagen) OPG105 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.3 kDa and the accession number is P20508.
TMPK-00524	CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His) CAIX,CA9,P54/58N,RCC,G250,EC 4.2.1.1,PMW1,CA-IX,MN	Cynomolgus	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The pred...
TMPK-00283	CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) RCC,EC 4.2.1.1,CA9,P54/58N,MN,CA-IX,CAIX,G250,PMW1	Human	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The...
TMPY-04920	ICA Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	INHCA, official full name is inhibitor of carbonic anhydrase, which is a member of the transferrin gene family. Unlike many members of that gene family it does not play a significant role in iron homeostasis but rather is an inhibitor of carbonic anhydrase. Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase.

重组蛋白

Carbonic Anhydrase 9 Protein, Human, Recombinant (His)

Cat.No: TMPY-00690

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00689

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 12 Protein, Human, Recombinant (His)

Cat.No: TMPY-00694

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01735

Species: Human

Expression System: E. coli

Carbonic Anhydrase 9 Protein, Canine, Recombinant (His)

Cat.No: TMPY-02990

Species: Canine

Expression System: HEK293 Cells

Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01700

Species: Mouse

Expression System: HEK293 Cells

Carbonic Anhydrase 1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00731

Species: Human

Expression System: E. coli

Carbonic Anhydrase 9 Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-02989

Species: Canine

Expression System: HEK293 Cells

Carbonic Anhydrase 14 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00691

Species: Mouse

Expression System: HEK293 Cells

Carbonic Anhydrase 3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01761

Species: Human

Expression System: E. coli

Carbonic Anhydrase VB Protein, Human, Recombinant (His)

Cat.No: TMPY-02133

Species: Human

Expression System: E. coli

Carbonic Anhydrase 7 Protein, Human, Recombinant (His)

Cat.No: TMPY-02277

Species: Human

Expression System: E. coli

Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06939

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 2 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03259

Species: Rat

Expression System: E. coli

Carbonic Anhydrase 8 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02301

Species: Mouse

Expression System: E. coli

Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06936

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00513

Species: Human

Expression System: CHO Cells

Carbonic Anhydrase 10 Protein, Human, Recombinant

Cat.No: TMPY-00693

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 14 Protein, Human, Recombinant (His)

Cat.No: TMPY-00967

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 12 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00688

Species: Mouse

Expression System: HEK293 Cells

Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00478

Species: Cynomolgus

Expression System: HEK293 Cells

Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO)

Cat.No: TMPH-03258

Species: Rat

Expression System: E. coli

Carbonic Anhydrase 10 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02302

Species: Mouse

Expression System: HEK293 Cells

Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02111

Species: Mouse

Expression System: E. coli

Carbonic Anhydrase 4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01327

Species: Mouse

Expression System: HEK293 Cells

Carbonic Anhydrase 8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01706

Species: Human

Expression System: E. coli

Carbonic Anhydrase 10 Protein, Human, Recombinant (His)

Cat.No: TMPY-01351

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 11 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00701

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 12 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06944

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00283

Species: Human

Expression System: HEK293 Cells

CA5A Protein, Human, Recombinant

Cat.No: TMPH-01038

Species: Human

Expression System: HEK293 Cells

CA5A Protein, Human, Recombinant (His)

Cat.No: TMPY-01877

Species: Human

Expression System: E. coli

E8L Protein, Monkeypox virus, Recombinant (His)

Cat.No: TMPK-01252

Species: Monkeypox virus

Expression System: E. coli

CA13 Protein, Human, Recombinant (His)

Cat.No: TMPY-01734

Species: Human

Expression System: E. coli

Vaccinia virus (strain Copenhagen) OPG105 Protein (His & SUMO)

Cat.No: TMPH-03655

Species: VACV

Expression System: E. coli

CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00524

Species: Cynomolgus

Expression System: HEK293 Cells

CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00283

Species: Human

Expression System: HEK293 Cells

ICA Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04920

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T10231	Acetazolamide-d3 醋氮酰胺 D3	Others	Others
	Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.
TMID-0299	Zonisamide-d4
	Zonisamide-d4 是 Zonisamide 的氘代化合物。Zonisamide 的 CAS 号为 68291-97-4。Zonisamide 是锌酶碳酸酐酶 (carbonic anhydrase) 的有效抑制剂，对人类线粒体同工酶 hCA II 和 hCA V 作用的Ki值分别为 35.2 nM 和 20.6 nM。Zonisamide 具有抗癫痫活性，在癫痫、癫痫发作和帕金森病的研究中具有价值。
TMIH-0523	Sodium cyclamate-d4
	Sodium cyclamate-d4 是 Sodium cyclamate 的氘代化合物。Sodium cyclamate 的 CAS 号为 139-05-9。Cyclamic acid sodium是一种碳酸酐酶抑制剂，是食品和药品中使用最广泛的人工甜味剂之一。Cyclamic acid sodium在最大电休克惊厥发作模型显示出中等的抗惊厥活性。Cyclamic acid sodium可用于研究癌症。
T36059	Dichlorphenamide-13C6 Dichlorphenamide-13C6
	Dichlorphenamide-13C6is intended for use as an internal standard for the quantification of dichlorphenamide by GC- or LC-MS. Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor (Kis = 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively).1It lowers intraocular pressure in rabbits when 50 μl of a 10% solution is applied topically to the eye.2Dichlorphenamide rescues the potassium deficiency and prevents insulin-induc...
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...
T70186	Methazolamide-d6
	Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and re...

同位素标记化合物

Acetazolamide-d3

Cat.No: T10231

Synonym: 醋氮酰胺 D3

Target: Others

Cat.No: TMID-0299

Sodium cyclamate-d4

Cat.No: TMIH-0523

Dichlorphenamide-13C6

Cat.No: T36059

Synonym: Dichlorphenamide-13C6

Zonisamide-13C2,15N

Cat.No: T37847

Synonym: Zonisamide-13C2,15N

Methazolamide-d6

Cat.No: T70186

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