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Cat. No. | Product Name | ||
---|---|---|---|
L7110 | 抗高血压化合物库 | 678 compounds | |
678 种高血压相关的小分子,用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1462 |
Captopril
SQ 14225,甲巯丙脯酸,卡托普利,SQ-14534,SA333 |
RAAS | Endocrinology/Hormones |
Captopril (SA333) 是一种含巯基的,具有口服活性的血管紧张素转换酶(ACE)抑制剂 ,IC50=0.025 μM,广泛应用于高血压和充血性心力衰竭的研究。Captopril 也是NDM-1抑制剂,IC50=7.9 μM。 | |||
T20512 |
Captopril disulfide
SQ14,551,SQ 14,551,SQ-14,551 |
Others | Others |
Captopril disulfide, a metabolite of Captopril, is a new antihypertensive agent. | |||
T39885 |
Captopril EP Impurity E
|
Others | Others |
Captopril EP Impurity E is an impurity of Captopril. Captopril, also known as SQ-14534, is an orally active angiotensin-converting enzyme (ACE) inhibitor that contains a thiol group. It has antihypertensive properties and competes with ACE with an inhibitor constant (IC 50 ) of 0.025 μM. | |||
T60383 |
Captopril hydrochloride
|
Others | Others |
Captopril (SQ 14225) hydrochloride 是一种含巯基的口服活性血管紧张素转换酶(ACE)抑制剂,IC50值为0.025 μM,已广泛应用于高血压和充血性心力衰竭的研究。Captopril hydrochloride 也是 NDM-1抑制剂,IC50值为 7.9 μM。 | |||
T67511 |
Captopril EP Impurity D
|
Others | Others |
Captopril EP Impurity D 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67511,CAS号为 56970-78-6。 | |||
T74109 |
Captopril EP Impurity B
|
Others | Others |
CaptoprilEPImpurity B 是一种 Captopril 的杂质。Captopril 是一种含巯基的口服活性血管紧张素转换酶(ACE)抑制剂 (IC50=0.025 μM)。 | |||
T25832 |
Moveltipril
Moveltipril calcium,MC-838,Altiopril calcium |
RAAS | Endocrinology/Hormones |
Moveltipril (Moveltipril calcium) 是一种强效血管紧张素转换酶(ACE)抑制剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2496 |
1,4-Anthraquinone
|
Others | Others |
1,4-Anthraquinone 是一种抗癌药物,在体外与柔红霉素相同纳摩尔范围内阻断核苷转运、抑制大分子合成、诱导 DNA 片段化并降低 L1210 白血病细胞的生长和活力。它被提议为一种用于高效液相色谱 (HPLC) 测定药物制剂中 N-乙酰半胱氨酸 (NAC) 和卡托普利 (CAP) 的新型柱前试剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01682 |
METTL7B Protein, Human, Recombinant (His)
Methyltransferase-like protein 7B,TMT1B,Thiol S-methyltransf... |
Human | E. coli |
Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-l-methionine to hydrogen sulfide and other thiol compounds including dithiothreitol, 7alpha-thiospironolactone, L-penicillamine, and captopril. | |||
TMPJ-00386 |
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Metalloprotease MPROT15,ACEH,Angiotensin-Converting Enzyme H... |
Human | HEK293 Cells |
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate... |