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Search Results for " caco-2 "
Targets Recommended: EGFR

40

抑制剂 & 化合物

16

天然产物

294

重组蛋白

2

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T9927 Panitumumab

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Panitumumab 是一种重组全人源 IgG2 单克隆抗体,可与表皮生长因子(EGFR)结合,具有抗肿瘤活性。
T2670 ML167

NCGC00188654,CID44968231

DYRK; CDK Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
ML167 (CID44968231) 是一种高选择性的 Cdc2 样激酶 4 抑制剂,IC50为 136 nM。
T1502 Vildagliptin

维达列汀,NVP-LAF 237,维格列汀,LAF237

Apoptosis; Ferroptosis; Proteasome; DPP-4 Apoptosis; Proteases/Proteasome; Ubiquitination
Vildagliptin (LAF237) 是一种选择性二肽基肽酶IV (DPP-IV) 抑制剂,在人 Caco-2 细胞中抑制 DPP-IV 的IC50为 3.5 nM。它具有出色的口服生物利用度和降血糖活性。
T1244 Celiprolol hydrochloride

Selecor,Selectrol,盐酸塞利洛尔

Adrenergic Receptor GPCR/G Protein; Neuroscience
Celiprolol hydrochloride (Selectrol) 是一种选择性肾上腺素受体调节剂,是一种选择性的和具有口服活性的β1肾上腺素受体拮抗剂,具有部分β2激动剂活性,具有降压和抗心绞痛的作用。
T0242L Sitagliptin phosphate monohydrate

MK-0431,MK-0431 phosphate monohydrate,西他列汀磷酸盐一水合物

Proteasome; DPP-4; Autophagy Autophagy; Proteases/Proteasome; Ubiquitination
Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) 是一种有效的 DPP-IV 抑制剂,在 Caco-2 细胞提取物中的 IC50 为 19 nM。
T18957 D-Ala-Lys-AMCA hydrochloride

Others Others
D-Ala-Lys-AMCA hydrochloride 是发射蓝色荧光的质子偶联寡肽转运蛋白 1 (PEPT1) 的已知底物。 D-Ala-Lys-AMCA 可能被转运到 Caco-2 细胞和肝癌细胞中。
T3148 MK-571 sodium

L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid

Leukotriene Receptor; LTR GPCR/G Protein; Immunology/Inflammation
MK-571 sodium (L-660711 sodium salt) 是一种可口服的选择性白三烯 D4受体拮抗剂,在豚鼠和人肺膜的 Ki 分别为0.222.1 nM。
T34973 Tyrphostin 8

4-Hydroxybenzylidenemalononitrile

EGFR; GTPase Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) 是一种有效的 GTP 酶抑制剂,对 EGFR 激酶有抑制作用, IC50 值为 560 μM。Tyrphostin 8 可抑制蛋白丝氨酸/苏氨酸钙调磷酸酶 (IC50=21 μM),增强 Caco-2 细胞中转铁蛋白受体介导的转吞作用,并增加口服胰岛素 - 转铁蛋白的降血糖作用。
T23358 Sitagliptin phosphate

磷酸西他列汀,Januvia,MK-0431 phosphate,Sitagliptin (phosphate)

DPP-4; Autophagy Autophagy; Proteases/Proteasome
Sitagliptin phosphate (MK-0431 phosphate) 是一种二肽基肽酶 4 (DPP4) 抑制剂,在 Caco-2 细胞中,IC50值为 19 nM。
T0242 Sitagliptin

西他列汀,MK0431,西格列汀

Proteasome; DPP-4; Autophagy Autophagy; Proteases/Proteasome; Ubiquitination
Sitagliptin (MK0431) 是一种有效的 DPP4抑制剂,在 Caco-2 细胞中,IC50值为 19 nM。它是一种新型口服降糖药,可单独使用或与二甲双胍或噻唑烷二酮联合用于治疗 2 型糖尿病。
T37281 1-Palmitoleoyl glycerol

Others Others
1-Palmitoleoyl glycerol 是具有生物活性的单酰基甘油,在 Caco-2 细胞中可抑制 P-糖蛋白,还能诱导胸腺细胞凋亡。
T81910 L-Tryptophanylglycine

L-Tryptophanylglycine(Trp-gly)作为一种二肽,其对Caco-2细胞摄取Ceronapril具有抑制作用,表现出Ki值为7.19 mM。
T61076 Vildagliptin dihydrate

Others Others
Vildagliptin dihydrate (LAF237 dihydrate) is a powerful and stable dipeptidyl peptidase IV (DPP-IV) inhibitor, demonstrating selectivity with an IC50 of 3.5 nM in human Caco-2 cells. This compound exhibits exceptional oral bioavailability and significant antihyperglycemic activity [1].
T69897 MC-70 hydrochloride

Others Others
MC-70 hydrochloride is a potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively).
T83083 Anticancer agent 166

Others Others
Anticanceragent 166 (compound 3)表现出对Caco-2细胞的显著抑制效果,其半数抑制浓度(IC50)为9.6 nM。
T40930 (S)-Sitagliptin phosphate

(S)-Sitagliptin phosphate,(S)-MK-0431 phosphate

Others Others
(S)-Sitagliptin phosphate, the less active S-enantiomer of Sitagliptin phosphate, is a high-potency inhibitor of DPP4. It exhibits an IC50 of 19 nM in Caco-2 cell extracts.
T30491 BMS 183920

BMS-183920,BMS183920

Others Others
BMS-183920 is a diacid, potent angiotensin II receptor antagonist that improves Caco-2 cell permeability and in vivo oral absorption. The relative degree of hydrolysis (biological activation) and prodrug metabolism determines whether substantial improveme
T82489 eIF4E-IN-6

Others Others
eIF4E-IN-6(化合物4b)是一种针对eIF4E设计的抑制剂,可阻止其与cap mRNA的结合,其化学结构为GMP类似物。该化合物在Caco-2、HepG-2和MCF-7细胞系中显示出细胞毒性效果,其IC50值分别约为31、27和21 μM。
T32242 IWP-051

IWP051

Others Others
IWP-051 is a potent, orally active sGC stimulator (EC50 = 290nM). IWP-051 showed >99% plasma protein binding, high metabolic stability, high permeability, and no efflux in a Caco-2 model of intestinal absorption. IWP-051 achieves good alignment of pote
T61783 Antimicrobial agent-1

Others Others
Antimicrobial Agent-1 (compound 6C) shows strong activity (MIC = 2 μg/mL) against TolC mutant E. coli. Additionally, it synergistically interacts with Colistin to exhibit enhanced activity against Gram-negative bacteria. Importantly, Antimicrobial Agent-1 exhibits no cytotoxic effects on mammalian cell lines. Its MIC values on Caco-2 and Vero cell lines are greater than 128 μg/mL [1].
T18958 D-Ala-Lys-AMCA TFA (375822-19-8 free base)

D-Ala-Lys-AMCA TFA

Others Others
D-Ala-Lys-AMCA TFA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into Caco-2 cells and liver cancer cells.
T70908 EST64454 free base

Others Others
EST64454 is a σ1 receptor (σ1R) antagonist clinical candidate for the treatment of pain. EST64454 shows an outstanding aqueous solubility, which together with its high permeability in Caco-2 cells will allow its classification as a BCS class I compound. It also shows high metabolic stability.
T80142 Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)

c(GRGDSP)

Integrin Cytoskeletal Signaling
Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)(c(GRGDSP))为RGD 抑制肽。该化合物作为合成的α5β1整联蛋白配体,能够竞争性阻断 invasin(Inv)与Caco-2细胞表面α5β1整联蛋白的相互结合。
T18959 D-Ala-Lys-AMCA

Others Others
D-Ala-Lys-AMCA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into Caco-2 cells and liver cancer cells.
T82617 D-Ala-Lys-AMCA TFA

D-Ala-Lys-AMCA是一个已知的PEPT1底物,具有发射蓝色荧光的性质。该化合物可被转运至肝癌细胞及Caco-2细胞。D-Ala-Lys-AMCA能够作为工具用于评估PEPT1的特异性底物或其抑制剂。
T82314 GK444

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
GK444(Compound 15a),一种针对HDAC1/2的抑制剂,IC50分别为HDAC1和HDAC2的100 nM与92 nM。其对Caco-2细胞的IC50为4.1μM,并能下调原代正常人肺成纤维细胞中TGF-β1刺激的COL1A1 mRNA水平。此外,GK444还能抑制博来霉素诱发的小鼠肺纤维化。
T79256 DPP-4-IN-8

Others Others
DPP-4-IN-8 (compound 27) 是一种高效的选择性DPP4抑制剂,具有 0.96 μM 的 Ki。该化合物能够抑制 Caco-2 和 HepG-2 细胞中的 DPP4 二肽酶活性,并剂量依赖性地降低 TNF-α、IL-6 和 IL-1β 的表达水平[1]。
T35815 Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)

Others Others
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. Vildagliptin carboxylic acid metabolite has an IC50 value of 477 μM for DPP-4 in human Caco-2 cells. It is formed from hydrolysis of the cyano group on vildagliptin.
T78793 MAOA-IN-1

Monoamine Oxidase Neuroscience
MAOA-IN-1(化合物15)是一种口服有效的MAOA抑制剂,对前列腺癌细胞显示出细胞毒性。该化合物表现出Caco-2渗透性,同时具有较低的CNS渗透性。MAOA-IN-1可以用于研究抗癌和抗炎适应症。
T61504 PKM2 activator 3

Others Others
PKM2 activator 3 is a highly potent compound that activates PKM2, with an AC 50 value of 90 nM. It exhibits excellent Caco-2 permeability, a low efflux ratio, and remarkable microsomal stability. PKM2 activator 3 is particularly valuable for anticancer research purposes [1]. (AC 50: the concentration at which 50% enzyme activation occurs.)
T79915 Antioxidant agent-15

COX Immunology/Inflammation; Neuroscience
Antioxidant agent-15 (Compound 4) 显示出显著的抗氧化抑制活性,其 IC50 为 15.44 nM。在细胞水平上,Antioxidant agent-15 对Hela、Hep G2Caco-2肿瘤细胞生长的抑制作用各自具有不同的 IC50 值,分别为 395.26 nM、4000.4 nM 和 24.6 nM。
T36410 9(E),11(E),13(E)-Octadecatrienoic Acid

Others Others
9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid. It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner. In vitro, β-ESA induces DNA fragmentation and upregulation of pro-apoptotic Bax mRNA. β-ESA decreases protein expression of the apoptosis suppression factor Bcl-2 and induces a...
T36035 CAY10784

Others Others
CAY10784 is a STAT3 inhibitor (IC50= 0.74 μM in a reporter assay) and a derivative of WP1066 .1It inhibits proliferation of HeLa, Caco-2, A549, A375, U87MG, and HL-60 cancer cells (IC50s = 1.8, 1.8, 3, 2.8, 2.3, and 1.2 μM, respectively) but not PC3 or HT-29 cancer cells (IC50s = >10 μM for both). CAY10784 is also active againstH. pyloriandC. jejuni(MICs = 1.6 and 4.7 μM, respectively).2 1.Lü, Z., Li, X., Li, K., et al.Structure-activity study of nitazoxanide derivatives as novel STAT3 pathway i...
T38072 HSGN-218

Others Others
HSGN-218 is a gut-restrictive antibiotic.1It is active againstC. difficile(MIC = 0.007 μg/ml) and clinical isolates ofC. difficile(MICs = 0.003-0.03 μg/ml) and is not cytotoxic to Caco-2 cells when used at concentrations ranging from 4 to 64 μg/ml. HSGN-218 (50 mg/kg) increases survival and protects mice fromC. difficilerecurrence in mouse models ofC. difficileinfection. 1.Naclerio, G.A., Abutaleb, N.S., Li, D., et al.Ultrapotent inhibitor of Clostridioides difficile growth, which suppresses rec...
T36887 8(E),10(E),12(Z)-Octadecatrienoic Acid

Others Others
8(E),10(E),12(Z)-Octadecatrienoic acid is a conjugated polyunsaturated fatty acid (PUFA) that has been found inC. officinalisseed oil and has anticancer activity.1,2,3It inhibits the growth of Caco-2 cells when used at concentrations ranging from 10 to 50 μM.28(E),10(E),12(Z)-Octadecatrienoic acid (10 μM) induces formation of thiobarbituric acid reactive substances (TBARS) and apoptosis in DLD-1 colorectal adenocarcinoma cells.3It also inhibits prostaglandin biosynthesis in sheep vesicular gland...
T36698 9(Z),11(E),13(E)-Octadecatrienoic Acid

Others Others
9(Z),11(E),13(E)-Octadecatrienoic Acid (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1...
T36517 Resveratrol-3-O-sulfate sodium

Others Others
Resveratrol-3-O-sulfate is a metabolite of resveratrol . In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 μM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 μM, and induces apoptosis at conc...
T36889 Methyl alpha-eleostearate

Others Others
Methyl alpha-eleostearate (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1 cells supple...
T36888 9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester

Others Others
9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPA...
T61259 Valganciclovir

Others Others
Valganciclovir 是ganciclovir 的原药,具有抗巨细胞病毒CMV 感染的活性。

化合物

Panitumumab
Cat.No: T9927
Synonym:
Target: EGFR
ML167
Cat.No: T2670
Synonym: NCGC00188654,CID44968231
Target: DYRK, CDK
Vildagliptin
Cat.No: T1502
Synonym: 维达列汀,NVP-LAF 237,维格列汀,LAF237
Target: Apoptosis, Ferroptosis, Proteasome, DPP-4
Celiprolol hydrochloride
Cat.No: T1244
Synonym: Selecor,Selectrol,盐酸塞利洛尔
Target: Adrenergic Receptor
Sitagliptin phosphate monohydrate
Cat.No: T0242L
Synonym: MK-0431,MK-0431 phosphate monohydrate,西他列汀磷酸盐一水合物
Target: Proteasome, DPP-4, Autophagy
D-Ala-Lys-AMCA hydrochloride
Cat.No: T18957
Synonym:
Target: Others
MK-571 sodium
Cat.No: T3148
Synonym: L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid
Target: Leukotriene Receptor, LTR
Tyrphostin 8
Cat.No: T34973
Synonym: 4-Hydroxybenzylidenemalononitrile
Target: EGFR, GTPase
Sitagliptin phosphate
Cat.No: T23358
Synonym: 磷酸西他列汀,Januvia,MK-0431 phosphate,Sitagliptin (phosphate)
Target: DPP-4, Autophagy
Sitagliptin
Cat.No: T0242
Synonym: 西他列汀,MK0431,西格列汀
Target: Proteasome, DPP-4, Autophagy
1-Palmitoleoyl glycerol
Cat.No: T37281
Synonym:
Target: Others
L-Tryptophanylglycine
Cat.No: T81910
Synonym:
Target:
Vildagliptin dihydrate
Cat.No: T61076
Synonym:
Target: Others
MC-70 hydrochloride
Cat.No: T69897
Synonym:
Target: Others
Anticancer agent 166
Cat.No: T83083
Synonym:
Target: Others
(S)-Sitagliptin phosphate
Cat.No: T40930
Synonym: (S)-Sitagliptin phosphate,(S)-MK-0431 phosphate
Target: Others
BMS 183920
Cat.No: T30491
Synonym: BMS-183920,BMS183920
Target: Others
eIF4E-IN-6
Cat.No: T82489
Synonym:
Target: Others
IWP-051
Cat.No: T32242
Synonym: IWP051
Target: Others
Antimicrobial agent-1
Cat.No: T61783
Synonym:
Target: Others
D-Ala-Lys-AMCA TFA (375822-19-8 free base)
Cat.No: T18958
Synonym: D-Ala-Lys-AMCA TFA
Target: Others
EST64454 free base
Cat.No: T70908
Synonym:
Target: Others
Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
Cat.No: T80142
Synonym: c(GRGDSP)
Target: Integrin
D-Ala-Lys-AMCA
Cat.No: T18959
Synonym:
Target: Others
D-Ala-Lys-AMCA TFA
Cat.No: T82617
Synonym:
Target:
GK444
Cat.No: T82314
Synonym:
Target: HDAC
DPP-4-IN-8
Cat.No: T79256
Synonym:
Target: Others
Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)
Cat.No: T35815
Synonym:
Target: Others
MAOA-IN-1
Cat.No: T78793
Synonym:
Target: Monoamine Oxidase
PKM2 activator 3
Cat.No: T61504
Synonym:
Target: Others
Antioxidant agent-15
Cat.No: T79915
Synonym:
Target: COX
9(E),11(E),13(E)-Octadecatrienoic Acid
Cat.No: T36410
Synonym:
Target: Others
CAY10784
Cat.No: T36035
Synonym:
Target: Others
HSGN-218
Cat.No: T38072
Synonym:
Target: Others
8(E),10(E),12(Z)-Octadecatrienoic Acid
Cat.No: T36887
Synonym:
Target: Others
9(Z),11(E),13(E)-Octadecatrienoic Acid
Cat.No: T36698
Synonym:
Target: Others
Resveratrol-3-O-sulfate sodium
Cat.No: T36517
Synonym:
Target: Others
Methyl alpha-eleostearate
Cat.No: T36889
Synonym:
Target: Others
9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester
Cat.No: T36888
Synonym:
Target: Others
Valganciclovir
Cat.No: T61259
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TQ0265 Indolelactic acid

Endogenous Metabolite Metabolism
Indolelactic acid 是 Azotobacter vinelandii 培养中的色氨酸分解代谢物。
T7210 Guanosine 5'-diphosphate

GDP,鸟苷-5ˊ-二磷酸

Endogenous Metabolite Metabolism
Guanosine 5'-diphosphate (GDP) 是核苷二磷酸,是潜在的铁动员剂,能够阻断铁调素-铁转运蛋白相互作用并调节白细胞介素-6 (IL-6)/stat-3 途径。
T19676 Tributyrin

NSC661583,NSC 661583,NSC-661583,甘油三丁酸酯

Apoptosis Apoptosis
Tributyrin (Glyceryl tributyrate) 是一种中性短链脂肪酸甘油三酯,是一种稳定且吸收迅速的丁酸前药。 它通过生物膜扩散并被细胞内脂肪酶代谢,在体内将有效的丁酸直接释放到细胞中,有抗增殖、促凋亡和诱导分化作用。
TN1237 3-O-Methylgallic acid

3,4-Dihydroxy-5-methoxybenzoic acid,3-O-甲基没食子酸

Apoptosis; NF-κB; OCT; DNA/RNA Synthesis; STAT Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; JAK/STAT signaling; Membrane transporter/Ion channel; NF-κB; Stem Cells
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) 是一种花青素代谢产物,具有强大的抗氧化能力。它还诱导细胞凋亡并具有抗癌作用,可抑制 Caco-2 细胞增殖,IC50值为 24.1 μM。
TN3967 Epieriocalyxin A

ERK; BCL; ROS; Caspase; DNA/RNA Synthesis; JNK Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Proteases/Proteasome
Epieriocalyxin A 可以抑制 Caco-2 结肠癌细胞的生长。它可能是未来结肠癌治疗的潜在药物。
TN1740 Homoeriodictyol

高胜草酚,高圣草酚

5-HT Receptor; transporter; Sodium Channel; Drug Metabolite GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
Homoeriodictyol 是 Eriocitrin 的代谢物,属于黄酮类。Eriocitrin 是强效抗氧化剂。
T5S0890 Oleandrin

Neriostene,Folinerin,Foliandrin,欧夹竹桃苷

Apoptosis; ATPase; Potassium Channel; Sodium Channel Apoptosis; Membrane transporter/Ion channel
Oleandrin (Folinerin) 是夹竹桃属中的一种类固醇,可抑制Na+/K+-ATPase 活性,IC50为 620 nM。
T6S1315 Oroxylin A

千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮,具有较强的抗癌作用。
T81797 Microcystin-LF

Microcystin-LF 是 Microcystin-LR 的苯丙氨酸变体,属于细菌代谢物,且对 Caco-2 细胞显示出细胞毒性。
TN1387 Angelol B

Others Others
The absorption and transport of angelol A and Angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
TN7405 Ganolucidic acid E

Others Others
Ganolucidic acid E effectively suppresses the proliferation of three human cancer cell lines: Caco-2 (colon cancer), HepG2 (hepatocellular carcinoma), and HeLa (cervical cancer).
TN1386 Angelol A

当归酚A,当归醇A

Others Others
Angelol A and angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
TN6645 Lucidumol A

Lucidumol A has relatively good effect against aldose reductase with IC50 of 19.1uM. Lucidumol A has cytotoxic activity, it reduced cell growth in three human carcinoma cells (Caco-2, HepG2, and HeLa cells) dose dependently with LC50s from 20.87 to 84.36
TQ0164 Dodecanoic acid ingenol ester

正十二烷酸巨大戟酯,13-Oxyingenol dodecanoat

Others Others
Dodecanoic acid ingenol ester, a natural compound, shows moderate cytotoxicity with IC50 values being 35.59 μM (Caco-2), 24.04 μM (MCF-7), and 22.24 μM (MCF-7/ADM).
T37810 6',7'-Epoxybergamottin

Others Others
6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo...
TN2190 Scoulerine

Apoptosis; Beta-Secretase; BACE; Parasite Apoptosis; Microbiology/Virology; Neuroscience
Scoulerine 是抗有丝分裂化合物。它抑制细胞增殖,阻止细胞周期,并诱导癌细胞凋亡。它也是BACE1(淀粉样前体蛋白裂解酶 1) 的抑制剂。

天然产物

Indolelactic acid
Cat.No: TQ0265
Synonym:
Target: Endogenous Metabolite
Guanosine 5'-diphosphate
Cat.No: T7210
Synonym: GDP,鸟苷-5ˊ-二磷酸
Target: Endogenous Metabolite
Tributyrin
Cat.No: T19676
Synonym: NSC661583,NSC 661583,NSC-661583,甘油三丁酸酯
Target: Apoptosis
3-O-Methylgallic acid
Cat.No: TN1237
Synonym: 3,4-Dihydroxy-5-methoxybenzoic acid,3-O-甲基没食子酸
Target: Apoptosis, NF-κB, OCT, DNA/RNA Synthesis, STAT
Epieriocalyxin A
Cat.No: TN3967
Synonym:
Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK
Homoeriodictyol
Cat.No: TN1740
Synonym: 高胜草酚,高圣草酚
Target: 5-HT Receptor, transporter, Sodium Channel, Drug Metabolite
Oleandrin
Cat.No: T5S0890
Synonym: Neriostene,Folinerin,Foliandrin,欧夹竹桃苷
Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel
Oroxylin A
Cat.No: T6S1315
Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether
Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy
Microcystin-LF
Cat.No: T81797
Synonym:
Target:
Angelol B
Cat.No: TN1387
Synonym:
Target: Others
Ganolucidic acid E
Cat.No: TN7405
Synonym:
Target: Others
Angelol A
Cat.No: TN1386
Synonym: 当归酚A,当归醇A
Target: Others
Lucidumol A
Cat.No: TN6645
Synonym:
Target:
Dodecanoic acid ingenol ester
Cat.No: TQ0164
Synonym: 正十二烷酸巨大戟酯,13-Oxyingenol dodecanoat
Target: Others
6',7'-Epoxybergamottin
Cat.No: T37810
Synonym:
Target: Others
Scoulerine
Cat.No: TN2190
Synonym:
Target: Apoptosis, Beta-Secretase, BACE, Parasite
Cat. No. Product Name Species Expression System
TMPY-00539 GSTA1 Protein, Human, Recombinant (His)

glutathione S-transferase alpha 1,GTH1,GST2,glutath...

Human HEK293 Cells
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno...
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02096 TACI Protein, Human, Recombinant (His)

RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...

Human HEK293 Cells
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...

Human E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-02011 CD96 Protein, Human, Recombinant (His)

CD96 molecule,TACTILE

Human HEK293 Cells
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPY-01717 VEGF164 Protein, Mouse, Recombinant

vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子

Mouse Baculovirus Insect Cells
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His)

A630052E07Rik,OSF-2,Osf2,PLF,AI74...

Mouse HEK293 Cells
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Protein T1,suppression of tumorigenicity 2,Ly84,DER...

Mouse HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His)

SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP...

Human HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-00751 TrkB Protein, Human, Recombinant (His)

trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...

Human HEK293 Cells
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-05288 PLGF/PGF Protein, Human, Recombinant (aa 19-149)

PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...

Human E. coli
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-04844 BTN3A1 Protein, Human, Recombinant (His)

BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2...

Human HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His)

KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL...

Human E. coli
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-02820 SDF-1/CXCL12 Protein, Human, Recombinant (isoform a)

SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1

Human E. coli
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01935 c-Kit Protein, Human, Recombinant (His)

PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-04644 PDGFB Protein, Human, Recombinant (His)

platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...

Human P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-01985 CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

FCGR2,FCGR21,CD32A,FCG2,...

Human HEK293 Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04356 GSK3B Protein, Human, Recombinant (His)

glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β

Human Baculovirus Insect Cells
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02500 YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

Gp39,AW208766,Brp39,chitinase 3 like 1

Mouse HEK293 Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
TMPY-05414 NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

D6H12S2489E,NKG2-D,killer cell le...

Mouse Baculovirus Insect Cells
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-01871 IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

interleukin 5 receptor, alpha,IL5R,CD125,CDw12<...

Human HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293)

HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...

Human HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01359 ST2/IL-1 RL1 Protein, Human, Recombinant (His)

IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His)

KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...

Human E. coli
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-00747 Nectin-2 Protein, Human, Recombinant (His)

PVRR2,Nectin-2,poliovirus receptor-related...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-04051 c-Kit Protein, Human, Recombinant (hFc)

SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene h...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
TMPY-05427 CD19 Protein, Human, Recombinant (hFc)

CVID3,B4,CD19 molecule

Human HEK293 Cells
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His)

TGFR-2,TGF-beta type II receptor,Transforming growt...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-00127 M-CSF/CSF1 Protein, Human, Recombinant

集落刺激因子,CSF-1,MCSF,M-CSF,colony stimulating factor 1 (macroph...

Human HEK293 Cells
M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
TMPY-04116 KRAS Protein,Human,Recombinant(G12C & Q61H, His)

NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2

Human E. coli
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-02231 TrkB Protein, Mouse, Recombinant (His)

trk-B,neurotrophic tyrosine kinase, receptor, type 2

Mouse HEK293 Cells
TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-02432 VEGF164 Protein, Rat, Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Rat Baculovirus Insect Cells
VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-00850 ST2/IL-1 RL1 Protein, Human, Recombinant

ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
TMPY-02367 Neuropilin-1 Protein, Human, Recombinant (isoform b, His)

neuropilin 1,NRP,VEGF165R,BDCA4,Neuropilin-1,NP1,CD304

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
TMPY-00849 ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-04829 G-CSF Protein, Human, Recombinant

G-CSF,colony stimulating factor 3 (granulocyte),集落刺激因子,CSF3O...

Human HEK293 Cells
G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
TMPY-00871 LAYN Protein, Human, Recombinant (hFc)

layilin

Human HEK293 Cells
LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
TMPY-01199 CD74 Protein, Human, Recombinant (His)

II,DHLAG,Ia-GAMMA,CD74 molecule, major histocompatibility co...

Human HEK293 Cells
CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
TMPY-00005 FGF-8a Protein, Human, Recombinant

fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-03425 Tau Protein, Human, Recombinant (His)

PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as...

Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPY-02358 CD98 Protein, Mouse, Recombinant (His)

NACAE,AI314110,Ly-m10,Cd98,Mgp-2hc,4F2HC,L...

Mouse HEK293 Cells
CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2.
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc)

HML2,CD301,CLECSF13,HML,MGL,C-type lectin domain fa...

Human HEK293 Cells
CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPY-05586 CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated

TMIGD2,IGPR-1,transmembrane and immunoglobulin doma...

Human HEK293 Cells
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu...
TMPY-00748 Nectin-2 Protein, Human, Recombinant

PRR2,Nectin-2,PVRR2,poliovirus re...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-00392 PAM Protein, Human, Recombinant (His)

PAL,peptidylglycine alpha-amidating monooxygenase,peptidylgl...

Human HEK293 Cells
PAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 94.4 kDa and the accession number is P19021-2.
TMPY-01726 Neuroligin-1 Protein, Human, Recombinant (His)

neuroligin 1,NL1

Human HEK293 Cells
Neuroligin-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72 kDa and the accession number is Q8N2Q7-2.
TMPY-03597 VIP Protein, Human, Recombinant (His)

PHM27,vasoactive intestinal peptide

Human HEK293 Cells
VIP, or vasoactive intestinal peptide, is a neuropeptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, and it exerts its actions through three G-protein-coupled receptors (PAC1, VPAC1, and VPAC2). VIP is synthesized by trophoblast cells; it regulates trophoblast cell function and interaction with the major immune cell populations present in the pregnant uterus.
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重组蛋白

GSTA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00539
Species: Human
Expression System: HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
Cat.No: TMPY-00891
Species: Human
Expression System: HEK293 Cells
TACI Protein, Human, Recombinant (His)
Cat.No: TMPY-02096
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Cat.No: TMPY-04113
Species: Human
Expression System: E. coli
CD96 Protein, Human, Recombinant (His)
Cat.No: TMPY-02011
Species: Human
Expression System: HEK293 Cells
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Mouse, Recombinant
Cat.No: TMPY-01717
Species: Mouse
Expression System: Baculovirus Insect Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
Cat.No: TMPY-00341
Species: Human
Expression System: HEK293 Cells
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01613
Species: Mouse
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Cat.No: TMPJ-00850
Species: Mouse
Expression System: HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His)
Cat.No: TMPY-01691
Species: Human
Expression System: HEK293 Cells
TrkB Protein, Human, Recombinant (His)
Cat.No: TMPY-00751
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
Cat.No: TMPY-05288
Species: Human
Expression System: E. coli
BTN3A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04844
Species: Human
Expression System: HEK293 Cells
KRAS Protein, Human, Recombinant (G12D, His)
Cat.No: TMPY-06056
Species: Human
Expression System: E. coli
SDF-1/CXCL12 Protein, Human, Recombinant (isoform a)
Cat.No: TMPY-02820
Species: Human
Expression System: E. coli
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
c-Kit Protein, Human, Recombinant (His)
Cat.No: TMPY-01935
Species: Human
Expression System: HEK293 Cells
PDGFB Protein, Human, Recombinant (His)
Cat.No: TMPY-04644
Species: Human
Expression System: P. pastoris (Yeast)
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-01985
Species: Human
Expression System: HEK293 Cells
GSK3B Protein, Human, Recombinant (His)
Cat.No: TMPY-04356
Species: Human
Expression System: Baculovirus Insect Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02500
Species: Mouse
Expression System: HEK293 Cells
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05414
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
Cat.No: TMPY-01871
Species: Human
Expression System: HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-02792
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01359
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human, Recombinant (Q61H, His)
Cat.No: TMPY-01888
Species: Human
Expression System: E. coli
Nectin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00747
Species: Human
Expression System: HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04051
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05427
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00335
Species: Mouse
Expression System: HEK293 Cells
M-CSF/CSF1 Protein, Human, Recombinant
Cat.No: TMPY-00127
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
Cat.No: TMPY-04116
Species: Human
Expression System: E. coli
TrkB Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02231
Species: Mouse
Expression System: HEK293 Cells
VEGF164 Protein, Rat, Recombinant
Cat.No: TMPY-02432
Species: Rat
Expression System: Baculovirus Insect Cells
ST2/IL-1 RL1 Protein, Human, Recombinant
Cat.No: TMPY-00850
Species: Human
Expression System: HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (isoform b, His)
Cat.No: TMPY-02367
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00849
Species: Human
Expression System: HEK293 Cells
G-CSF Protein, Human, Recombinant
Cat.No: TMPY-04829
Species: Human
Expression System: HEK293 Cells
LAYN Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00871
Species: Human
Expression System: HEK293 Cells
CD74 Protein, Human, Recombinant (His)
Cat.No: TMPY-01199
Species: Human
Expression System: HEK293 Cells
FGF-8a Protein, Human, Recombinant
Cat.No: TMPY-00005
Species: Human
Expression System: E. coli
Tau Protein, Human, Recombinant (His)
Cat.No: TMPY-03425
Species: Human
Expression System: E. coli
CD98 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02358
Species: Mouse
Expression System: HEK293 Cells
CLEC10A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02971
Species: Human
Expression System: HEK293 Cells
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05586
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant
Cat.No: TMPY-00748
Species: Human
Expression System: HEK293 Cells
PAM Protein, Human, Recombinant (His)
Cat.No: TMPY-00392
Species: Human
Expression System: HEK293 Cells
Neuroligin-1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01726
Species: Human
Expression System: HEK293 Cells
VIP Protein, Human, Recombinant (His)
Cat.No: TMPY-03597
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
T35775 HT-2 Toxin-13C22

HT-2 Toxin-13C22

HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...
TMIJ-0142 Vildagliptin-d7

Vildagliptin-d7 是 Vildagliptin 的氘代化合物。Vildagliptin 的 CAS 号为 274901-16-5。Vildagliptin 是一种选择性二肽基肽酶IV (DPP-IV) 抑制剂,在人 Caco-2 细胞中抑制 DPP-IV 的IC50为 3.5 nM。它具有出色的口服生物利用度和降血糖活性。

同位素标记化合物

HT-2 Toxin-13C22
Cat.No: T35775
Synonym: HT-2 Toxin-13C22
Target:
Vildagliptin-d7
Cat.No: TMIJ-0142
Synonym:
Target:
TargetMol Loading
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