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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78204 |
CYP11A1-IN-1
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Others | Others |
CYP11A1-IN-1(化合物30)是一种针对CYP11A1的抑制剂,其IC50为201-2000 nM。该化合物主要应用于类固醇受体研究,尤其适用于雄激素受体依赖性疾病,例如前列腺癌的研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01084 |
CYP11A1 Protein, Human, Recombinant (His & SUMO)
Cholesterol side-chain cleavage enzyme, mitochondrial,CY... |
Human | E. coli |
CYP11A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.1 kDa and the accession number is P05108. | |||
TMPH-02143 |
NR5A1 Protein, Human, Recombinant (His)
Adrenal 4-binding protein,NR5A1,Steroidogenic factor 1,Fushi... |
Human | E. coli |
Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cA... |