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Search Results for " cyp "

Targets Recommended: CYP19A1 Dopamine Receptor GABA Receptor

183

抑制剂 & 化合物

23

天然产物

1

化合物库

35

重组蛋白

7

同位素标记化合物

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Cat. No.	Product Name
LF1030	LC高溶解性片段化合物库		9600 compounds

化合物库

LC高溶解性片段化合物库

Cat.No: LF1030

Compounds: 9600

Cat. No.	Product Name	Target	Signaling Pathways
T26834	BL-1020 Mesylate CYP-1020 Mesylate	Dopamine Receptor; GABA Receptor	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	BL-1020 Mesylate (CYP-1020 Mesylate) 是一种可口服的 GABA A 受体激动剂和 D2 拮抗剂，可降低多巴胺活性并增强GABAA活性。BL-1020 Mesylate 可用于研究神经分裂、阿尔茨海默症和双向认知障碍。
T10923	CYP17-IN-1	P450	Metabolism
	CYP17-IN-1 是一种有效的 CYP17 口服抑制剂，可抑制大鼠和人类的 CYP17，IC50 分别为 15.8 和 20.1 nM。
T10922	CYP11B2-IN-1	P450	Metabolism
	CYP11B2-IN-1 是一种有效的选择性 CYP11B2 抑制剂，对 CYP11B2 和 CYP11B1 的 IC50 分别为 2.3 nM 和 142 nM。
T67916	CYP4A11/CYP4F2-IN-2	P450	Metabolism
	CYP4A11/CYP4F2-IN-2 是一种有效的和具有口服活性的细胞色素 P450 (CYP) 4A11 和 CYP4F2 的双重抑制剂，IC50 值分别为 140 nM 和 40 nM。CYP4A11/CYP4F2-IN-2可从肝脏和肾脏中提取，具有治疗肾脏疾病的潜力。
T72501	CYP4A11/CYP4F2-IN-1	P450	Metabolism
	CYP4A11/CYP4F2-IN-1 是一种高效的小分子细胞色素 P450 (CYP) 4A11 和 CYP4F2 抑制剂，对P450 (CYP) 4A11 的 IC50 值为 19 nM，对 CYP4F2 的 IC50 值为 17 nM。CYP4A11/CYP4F2-IN-1 可用于研究肾脏疾病和心脑血管疾病。
T50011	CYP2A6-IN-1	Others	Others
	(2-methylpropyl)({[3-(trifluoromethyl)phenyl]methyl})amine 是一种选择性血清素受体激动剂，特异性靶向5-HT2A 和5-HT2C 受体，已被用于研究血清素在各种生理和病理条件下的作用。
T73040	CYP1B1-IN-4	P450	Metabolism
	CYP1B1-IN-4为选择性CYP1B1抑制剂（IC50=0.2 nM），属2,4-二芳基噻唑类化合物。其对细胞的毒性低，且在人类及大鼠肝微粒体中表现出稳定性。
T73042	CYP1B1-IN-5	P450	Metabolism
	CYP1B1-IN-5 是一种具有选择性和高效性的细胞色素 P450 1B1 (CYP1B1) 抑制剂，IC50 为 4.7 nM。CYP1B1-IN-5 可用于研究与代谢相关的疾病。
T27109	CYP1A1 inhibitor 8a	Others	Others
	CYP1A1 inhibitor 8a is a potent and selective CYP1A1 inhibitor. It antagonizes B[a]P mediated activation of aromatic hydrocarbon receptor (AhR) in yeast cells, thereby protects human cells from CYP1A1-mediated B[a]P toxicity.
T63496	CYP2C9/CYP2C19-IN-1	Others	Others
	CYP2C9/CYP2C19-IN-1 是无肝脏毒性和遗传毒性的CYP2C9/CYP2C19强效抑制剂，能够用于研究寨卡病毒 (ZIKV) 感染。
T63495	CYP2C1/CYP2C19-IN-2	Others	Others
	CYP2C1/CYP2C19-IN-2 是无肝脏毒性和遗传毒性的CYP2C9/CYP2C19强效抑制剂，能够用于研究寨卡病毒 (ZIKV) 感染。
T63954	CYP3A4-IN-1	Others	Others
	CYP3A4-IN-1 是细胞色素 P450 3A4 (CYP3A4) 的有效抑制剂 (IC50: 0.085 μM)。
T73039	CYP1B1-IN-3	Others	Others
	CYP1B1-IN-3为选择性CYP1B1抑制剂，其IC50值分别针对CYP1B1、CYP1A1、CYP1A2为6.6, 347.3, >10000 nM。该化合物能够抑制细胞迁移与侵袭，并作用于P-gp、AKT/ERK、FAK/SRC及EMT信号通路。
T6420	BMS-707035 N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	BMS707035是一种 HIV-1 整合酶抑制剂，IC50为15 nM。
T64249	CYP11B1-IN-2	Others	Others
	CYP11B1-IN-2 (compound 7aa) 是一种选择性的、口服具有活力的 CYP11B1 抑制剂，能够作用于 human CYP11B1 (IC50: 9 nM) 和 rat CYP11B1 (IC50: 25 nM)。CYP11B1-IN-2 能够用于研究皮质醇过量所致疾病。
T63337	CYP2C19-IN-1	Others	Others
	CYP2C19-IN-1 是强效的，无遗传毒性的、无肝脏毒性的 CYP2C19 抑制剂。 CYP2C19-IN-1 能够抑制 RNA 依赖的 RNA 聚合酶 (RdRP) (Ki: 6.16 μM)，能够用于研究寨卡病毒 (ZIKV) 感染。
T61287	CYP121A1-IN-1	Others	Others
	CYP121A1-IN-1 是一种有效的CYP121A1抑制剂，对抗结核分枝杆菌具有良好的活性 (H37RvMIC90～6.25 μM, ～2.2 μg/mL)。CYP121A1-IN-1 通过抑制 CYP121A1 介导的环(l-酪氨酸-l-酪氨酸)转化为真菌环素，可显著减少真菌环素的产生。
T64032	CYP3A4-IN-3	Others	Others
	CYP3A4-IN-3 是特异性的、高度亲和力的细胞色素 P450 3A4 (CYP3A4) (cytochrome P450 3A4 (CYP3A4)) 抑制剂 (IC50: 0.075 μM)。CYP3A4-IN-3 是利托那韦类似物，结构更加简单，且抑制效果是利托那韦的两倍。CYP3A4-IN-3 能够用做抗病毒剂和免疫抑制剂。
T64037	CYP3A4-IN-2	Others	Others
	CYP3A4-IN-2 是细胞色素 P450 3A4 (CYP3A4) (cytochrome P450 3A4 (CYP3A4)) 的特异性抑制剂 (IC50: 0.055 μM)。CYP3A4-IN-2 是利托那韦类似物，与利托那韦相比，其 R2 侧基的疏水性更高，抑制作用更强。CYP3A4-IN-2 能够作为免疫抑制剂及抗病毒剂。
T78204	CYP11A1-IN-1	Others	Others
	CYP11A1-IN-1（化合物30）是一种针对CYP11A1的抑制剂，其IC50为201-2000 nM。该化合物主要应用于类固醇受体研究，尤其适用于雄激素受体依赖性疾病，例如前列腺癌的研究。
T61082	CYP1B1-IN-2	Others	Others
	CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of CYP1B1, a cytochrome P450 enzyme. It exhibits an IC50 value of 0.52 nM [1].
T60723	CYP1B1-IN-1	Others	Others
	CYP1B1-IN-1 (Compound 9e) 是细胞色素 P450 1B1 (CYP1B1) 的选择性抑制剂 (IC 50 = 0.49 nM)。
T64154	CYP51/HDAC-IN-1	Others	Others
	CYP51/HDAC-IN-1 是一种口服具有活力的、有效的、双重 CYP51/HDAC 抑制剂。CYP51/HDAC-IN-1 能够抑制重要的毒力因子，可下调相关耐药基因的表达。CYP51/HDAC-IN-1 对热带念珠菌病和隐球菌性脑膜炎都表现出有效的治疗作用。
T79739	CYP51/PD-L1-IN-2	Others	Others
	CYP51/PD-L1-IN-2（compound L20）是一种具有抗真菌活性的喹唑啉化合物。它作为CYP51（IC50：0.263 μM）和PD-L1（IC50：0.017 μM）的双重抑制剂，能够在细胞周期的早期引发真菌细胞凋亡。CYP51/PD-L1-IN-2进一步显著降低IL-2、NLRP3、NF-κBp65等蛋白水平，触发线粒体损伤及ROS积累，终致真菌细胞裂解和死亡。
T79740	CYP51/PD-L1-IN-3	Others	Others
	CYP51/PD-L1-IN-3（compound L21）是一种具有抗真菌活性的喹唑啉化合物。作为CYP51(IC50: 0.205 μM) 和PD-L1(IC50: 0.039 μM) 的双重抑制剂，它能够引发真菌细胞在细胞周期早期的凋亡。此外，CYP51/PD-L1-IN-3 还能显著降低IL-2、NLRP3、NF-κBp65 蛋白的细胞内水平，并诱导线粒体损害及ROS 聚集，进而导致真菌细胞的裂解与死亡。
T78902	CYP51/PD-L1-IN-4	Others	Others
	CYP51/PD-L1-IN-4（化合物14a-2）是一种高效的双靶点抑制剂，其IC50值针对CYP51为0.17 μM，针对PD-L1为0.021 μM。该化合物在体外展现出卓越的抗真菌和抗耐药真菌能力，适用于真菌感染的研究。
T79738	CYP51/PD-L1-IN-1	Others	Others
	CYP51/PD-L1-IN-1（compound L11）是一种具有抗真菌活性的喹唑啉化合物，作为CYP51（IC50: 0.884 μM）和PD-L1（IC50: 0.083 μM）的双重抑制剂，能够在细胞周期早期引发真菌细胞的凋亡。该化合物还能有效减少IL-2、NLRP3、NF-κBp65等蛋白的细胞内水平，诱导线粒体损伤及ROS积聚，进而导致真菌细胞的破裂和死亡。
T74519	PROTAC CYP1B1 degrader-1	PROTACs	PROTAC
	PROTACCYP1B1 degrader-1 (Compound 6C) 是一种 α-萘黄酮嵌合衍生物，能够通过靶向 CYP1B1降解消除细胞色素 P450 (CYP)1B1 介导的耐药性，对 CYP1B1 和 CYP1A2 的 IC50分别为 95.1 和 9838.6 nM。PROTACCYP1B1 Degrader-1 可用于研究 CYP1B1过表达的前列腺癌。
T20968	CyPPA	Potassium Channel; Dopamine Receptor	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	CyPPA 是hSK2和hSK3的阳性调节剂，其EC50值分别为 5.6 μM 和14 μM。它对 hSK1 和 hIK 通道无活性。
T6814	Cyproheptadine hydrochloride Periactin hydrochloride,Anarexol,盐酸赛庚啶,Cyproheptadine HCl,Nuran	5-HT Receptor	GPCR/G Protein; Neuroscience
	Cyproheptadine hydrochloride (Periactin hydrochloride) 是一种 5-HT2A 受体拮抗剂，具有抗抑郁和抗血清素作用。它具有抗血小板活性，可用于血栓栓塞性疾病的研究。
T1025	Tranylcypromine (2-PCPA) hydrochloride 反苯环丙胺盐酸盐,Tranylcypromine (2-PCPA) HCl,SKF-385 HCl	Histone Demethylase; MAO	Chromatin/Epigenetic; Metabolism; Neuroscience
	Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl) 是一种单胺氧化酶抑制剂，对治疗重度抑郁症、心境恶劣障碍和非典型抑郁症有效。
T0174	Cyproheptadine hydrochloride sesquihydrate Peritol,盐酸赛庚啶半水合物,Periactin hydrochloride,Cyproheptadine hydrochloride,赛庚啶盐酸盐	5-HT Receptor; Histone Methyltransferase; Histamine Receptor	Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cyproheptadine hydrochloride sesquihydrate (Peritol) 是一种抗组胺剂，也是血清素和组胺2拮抗剂。
T1167	Cyproterone acetate Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮	Androgen Receptor	Endocrinology/Hormones
	Cyproterone acetate (Cyproterone 17-O-acetate) 是能够抗雄激素(IC50=7.1 nM) 和孕激素合成的类固醇。它与 progesteron 和糖皮质激素受体有亲和力。
T0168	Estradiol (cypionate) Depofemin,环戊丙酸雌二醇,Estradiol cypionate	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Estradiol cypionate (Depofemin) 是一种 Estradiol 的 17β-环戊丙酸酯，能够作用于雌激素受体。抑制ET-1的合成。
T77698	hCYP3A4 Fluorogenic substrate 1	Others; COX	Immunology/Inflammation; Neuroscience; Others
	hCYP3A4 Fluorogenic substrate 1 是邻苯二甲酰亚胺衍生物，对 COX 表现出低活性。
T7942	Tranylcypromine hemisulfate Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐	Histone Demethylase; MAO; Monoamine Oxidase	Chromatin/Epigenetic; Metabolism; Neuroscience
	Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂，可用于研究抑郁症和子宫内膜异位症。
T15033	Cyproconazole	Antibacterial	Microbiology/Virology
	Cyproconazole 是一种三唑类杀菌剂，在农业上用于保护作物免受多种真菌病原体的侵害。
TP2238	Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]	Others	Others
	Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] is a peptide from Cytochrome c, which is a small heme protein found loosely associated with the inner membrane of the mitochondrion. Cytochromes c from certain eukaryotes, including plants and fungi but not higher animals, contains methylated lysine residues at specific positions1. Cytochrome c is a required cofactor for Apaf-1 function2.
T131586	1,2-Dehydro-alpha-cyperone	Others	Others
	1,2-Dehydro-alpha-cyperone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131586。
T31154	Cypridina luciferin	Others	Others
	Cypridina luciferin is a bioactive chemical.
T36501	CYPMPO RR 071	Others	Others
	CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution and a hypoxanthine/xanthine oxidase system, respectively. CYPMPO traps superoxide radicals generated by bovine neutrophils as effectively as DEPMPO.[1] The high melting point (126°C),...
T74965	CypE-IN-1	Others	Others
	CypD-IN-1 是一种有效的亚型选择性亲环蛋白 E (CypE) 抑制剂。CypD-IN-1 具有 CypE 亲和力，IC50和 Ki 值分别为 0.013 μM 和 0.072 μM。CypD-IN-1 可用于多种疾病的研究，如氧化应激、神经退行性疾病、肝病、衰老、自噬和糖尿病。
T79914	Tranylcypromine SKF 385	Monoamine Oxidase	Neuroscience
	Tranylcypromine (SKF 385)为一种高效的单胺氧化酶抑制剂。
T79283	hCYP1B1-IN-1	Others	Others
	hCYP1B1-IN-1 (compound B18)为高效的hCYP1B1抑制剂(IC50=3.6 nM)，同时亦为芳香烃受体拮抗剂。该化合物展现优秀的代谢稳定性与细胞膜渗透性，能有效抑制MCF-7细胞迁移。
T79343	hCYP3A4-IN-1	Others	Others
	hCYP3A4-IN-1（化合物C6）是一种经口服时具有活性的hCYP3A4抑制剂，其对hCYP3A4的IC50值在人肝微粒体(HLM)为43.93 nM，在CHO-3A4稳定转染细胞系中为153.00 nM。hCYP3A4-IN-1通过竞争性抑制机制，有效抑制CYP3A4催化的N-乙基-1,8-萘二甲酰亚胺(NEN)羟基化反应，其Ki值为30.00 nM。
T73099	Etbicyphat Trimethylopropane phosphate	Others	Others
	Etbicyphat (Trimethylopropane phosphate)作为一种GABA(A)受体竞争性拮抗剂展现出显著效果。通过诱发海马体CA1神经元的类似癫痫的活动并与GABA(A)-benzodiazepine受体结合，Etbicyphat的作用机制得到了阐述。
T33627	Nematocyphol	Others	Others
	Nematocyphol is a triterpenoid from Euphorbia nematocypha hand-mazz.
T26117	Rolicyprine RMI 83027,RMI-83027,RMI83,027,RMI 83,027,RMI-83,027	Others	Others
	Rolicyprine is an antidepressant.
T20787	Cyphenothrin S-2703,Gokilaht,S2703,S 2703	Others	Others
	Cyphenothrin, a synthetic pyrethroid insecticide, is effective against cockroaches that have developed resistance to carbamate and organophosphorous insecticides.
T71997	CypD-IN-29	Others	Others
	CypD-IN-29 is a non-peptidic inhibitor of cyclophilin D as a neuroprotective agent in Aβ-induced mitochondrial dysfunction.

化合物

BL-1020 Mesylate

Cat.No: T26834

Synonym: CYP-1020 Mesylate

Target: Dopamine Receptor, GABA Receptor

Cat.No: T10923

Target: P450

Cat.No: T10922

Target: P450

CYP4A11/CYP4F2-IN-2

Cat.No: T67916

Target: P450

CYP4A11/CYP4F2-IN-1

Cat.No: T72501

Target: P450

Cat.No: T50011

Target: Others

Cat.No: T73040

Target: P450

Cat.No: T73042

Target: P450

CYP1A1 inhibitor 8a

Cat.No: T27109

Target: Others

CYP2C9/CYP2C19-IN-1

Cat.No: T63496

Target: Others

CYP2C1/CYP2C19-IN-2

Cat.No: T63495

Target: Others

Cat.No: T63954

Target: Others

Cat.No: T73039

Target: Others

Cat.No: T6420

Synonym: N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺

Target: HIV Protease

Cat.No: T64249

Target: Others

Cat.No: T63337

Target: Others

CYP121A1-IN-1

Cat.No: T61287

Target: Others

Cat.No: T64032

Target: Others

Cat.No: T64037

Target: Others

Cat.No: T78204

Target: Others

Cat.No: T61082

Target: Others

Cat.No: T60723

Target: Others

CYP51/HDAC-IN-1

Cat.No: T64154

Target: Others

CYP51/PD-L1-IN-2

Cat.No: T79739

Target: Others

CYP51/PD-L1-IN-3

Cat.No: T79740

Target: Others

CYP51/PD-L1-IN-4

Cat.No: T78902

Target: Others

CYP51/PD-L1-IN-1

Cat.No: T79738

Target: Others

PROTAC CYP1B1 degrader-1

Cat.No: T74519

Target: PROTACs

Cat.No: T20968

Target: Potassium Channel, Dopamine Receptor

Cyproheptadine hydrochloride

Cat.No: T6814

Synonym: Periactin hydrochloride,Anarexol,盐酸赛庚啶,Cyproheptadine HCl,Nuran

Target: 5-HT Receptor

Tranylcypromine (2-PCPA) hydrochloride

Cat.No: T1025

Synonym: 反苯环丙胺盐酸盐,Tranylcypromine (2-PCPA) HCl,SKF-385 HCl

Target: Histone Demethylase, MAO

Cyproheptadine hydrochloride sesquihydrate

Cat.No: T0174

Synonym: Peritol,盐酸赛庚啶半水合物,Periactin hydrochloride,Cyproheptadine hydrochloride,赛庚啶盐酸盐

Target: 5-HT Receptor, Histone Methyltransferase, Histamine Receptor

Cyproterone acetate

Cat.No: T1167

Synonym: Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮

Target: Androgen Receptor

Estradiol (cypionate)

Cat.No: T0168

Synonym: Depofemin,环戊丙酸雌二醇,Estradiol cypionate

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

hCYP3A4 Fluorogenic substrate 1

Cat.No: T77698

Target: Others, COX

Tranylcypromine hemisulfate

Cat.No: T7942

Synonym: Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐

Target: Histone Demethylase, MAO, Monoamine Oxidase

Cyproconazole

Cat.No: T15033

Target: Antibacterial

Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]

Cat.No: TP2238

Target: Others

1,2-Dehydro-alpha-cyperone

Cat.No: T131586

Target: Others

Cypridina luciferin

Cat.No: T31154

Target: Others

Cat.No: T36501

Synonym: RR 071

Target: Others

Cat.No: T74965

Target: Others

Tranylcypromine

Cat.No: T79914

Synonym: SKF 385

Target: Monoamine Oxidase

Cat.No: T79283

Target: Others

Cat.No: T79343

Target: Others

Cat.No: T73099

Synonym: Trimethylopropane phosphate

Target: Others

Cat.No: T33627

Target: Others

Cat.No: T26117

Synonym: RMI 83027,RMI-83027,RMI83,027,RMI 83,027,RMI-83,027

Target: Others

Cat.No: T20787

Synonym: S-2703,Gokilaht,S2703,S 2703

Target: Others

Cat.No: T71997

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5786	TETRAHYDROPIPERINE 四氢胡椒碱,Cosmoperine	P450; TRP/TRPV Channel	Membrane transporter/Ion channel; Metabolism
	Tetrahydropiperine (Cosmoperine) 是胡椒碱的环己基类似物，也是一种天然芳基戊酰胺，从Piper longum 分离得到。它对细胞色素 P450 (CYP) 同工型 CYP1A1/芳基烃羟化酶 (AHH；IC50=23 µM)具有抑制作用。
T1011	Itraconazole 伊曲康唑,R51211	P450; Hedgehog/Smoothened; Antibiotic; Autophagy; Antifungal	Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Stem Cells
	Itraconazole (R51211) 属于三唑类天然产物，是一种抗真菌剂，具有口服活性。Itraconazole 是一种 Hedgehog 信号通路拮抗剂，一种 oxysterol-binding protein (OSBP) 抑制剂，也是一种细胞色素 P-450 依赖性酶的抑制剂。
T6S0923	Hypericin Hypericine,金丝桃素,Cyclosan	Apoptosis; Antiviral; Influenza Virus; Tyrosine Kinases; Antibacterial; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Hypericin (Cyclosan) 是贯叶连翘的提取物，有抗菌、抗病毒、抗肿瘤和抗抑郁作用。
T5709	Cyperotundone	Others	Others
	Cyperotundone 是分离自 Nagarmotha (Cyperus rotundus) 中的一种倍半萜。
T5S1981	alpha-Cyperone (+)-α-Cyperone,α-香附酮,α-Cyperone	Others; Endogenous Metabolite	Metabolism; Others
	alpha-Cyperone (α-Cyperone) 与 IL-6, Cox-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。
TN4438	Ligucyperonol	Others	Others
	Ligucyperonol exhibits significant activities on protecting muscle cells from mild to moderate oxidative stress.
TN5681	Cypellocarpin C Camaldulenside,桉叶苷
	Cypellocarpin C shows potent in vitro antitumor-promoting activity, it also can suppress an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin.
T0671	2-Naphthol Betanaphthol,β-萘酚,乙萘酚	Others; Endogenous Metabolite	Metabolism; Others
	2-Naphthol 是一种 naphthalene 的代谢物，由细胞色素 P450 亚型 (CYP 1A1，CYP 1A2，CYP 2A1，CYP 2E1 和 CYP 2F2) 催化而成。2-Naphthol 具有细胞毒性。
T2761	Naringin dihydrochalcone Naringin DC,柚皮苷二氢查尔酮,柚皮甙二氢查尔酮	P450; NF-κB	Metabolism; NF-κB
	Naringin dihydrochalcone (Naringin DC) 是一种新型甜味剂，是来自柚皮苷的一种人工甜味剂。它也是一种CYP enzymes 的抑制剂。
T7970	7-Ethoxycoumarin	Others	Others
	7-Ethoxycoumarin 是细胞色素 P450(CYP) 的底物，现已被应用于多种 CYP 的功能表征。
T5594	Cedrol	P450; Antifungal	Metabolism; Microbiology/Virology
	Cedrol 是一种雪松烷倍半萜类叔醇，抑制细胞色素 P450 (CYP) 异构体 CYP2B6 和 CYP3A4，Kis 分别为 0.9 和 3.4 μM，具有抗炎，抗脓毒，抗痉挛，滋补，收敛，利尿，杀虫和抗真菌活性。
T2876	Flavone 2-Phenyl-4-benzopyron,黄酮,2-Phenyl-4-chromone,2-Phenylchromone	NOS; Endogenous Metabolite	Immunology/Inflammation; Metabolism
	Flavone (2-Phenyl-4-chromone) 是内源性代谢产物的一种。
T5778	5,7-DIMETHOXYFLAVONE	Anti-infection; P450	Metabolism; Microbiology/Virology
	5,7-Dimethoxyflavone 是一种 Kaempferia parviflora 的主要成分，具有抗肿瘤、抗肥胖及抗炎活性。它对细胞色素 P450 (CYP) 3As 具有抑制作用，也是抗乳腺癌蛋白 (BCRP) 抑制剂。
T11218	ε-Viniferin epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体	P450	Metabolism
	ε-Viniferin (epsilon-Viniferin) 提取自 Vitis vinifera，是 Resveratrol 的二聚体，能够抑制 CYP 家族,其 Ki=0.5~20 μM，具有抗氧化作用。
T3S0860	Gitogenin	UGT	Metabolism
	Gitogenin 是一种从Tribulus longipetalus 整株中分离出来的天然类固醇，是一种 UDP-葡萄糖醛酸转移酶 1A4 (UGT1A4) 和 α-葡萄糖苷酶的选择性抑制剂，其IC50分别为 0.69 µM (使用三氟拉嗪为底物) 和 37.2 μM，对人类主要细胞色素 P450 亚型的活性无抑制作用。
T5S2343	Acetylshikonin 乙酰紫草素,Acetyl shikonin	Others; P450; AChE	Metabolism; Neuroscience; Others
	Acetylshikonin 来源于紫草根，具有抗癌、抗炎作用。它是一种 AChE 抑制剂，具有很强的抗凋亡活性。它是一种非选择性的细胞色素 P450抑制剂，对所有 P450 亚型抑制的 IC50值范围为 1.4-4.0 μM。
T13520	6-Hydroxymelatonin	Others	Others
	6-Hydroxymelatonin is a primary metabolic of Melatonin, which is metabolized by CYP 1A2.
TN4130	Germacrone 4,5-epoxide	gp120/CD4; IL Receptor; P450	Immunology/Inflammation; Metabolism
	(4S,5S)-(+)-Germacrone-4,5-epoxide inhibits certain subtypes of cytochrome P450 (CYP).
T82305	Glucoarabin
	Glucoarabin是一种硫代葡萄糖苷，具备生物活性。在Hepa1c1c7细胞内，Glucoarabin的水解产物能够上调NQO1，而对细胞色素P450 (CYP) 1A1的活性无显著作用。
T40859	5-Hydroxy-8-methoxypsoralen 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen	Others	Others
	5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite derived from Xanthotoxin, which acts as a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). It is employed as an agent for the treatment of psoriasis, eczema, vitiligo, and certain cutaneous Lymphomas, in combination with phototherapy involving exposure to sunlight.
T36472	Tetrahydro-11-deoxy Cortisol	Others	Others
	Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cytochrome P450 (CYP) isoform CYP11B1. Urinary levels of THS are also elevated in patients with adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA) but are higher in patients with ACC compared to ACA.
TN7505	Thujopsene NSC 44707	Others	Others
	Thujopsene, a sesquiterpene found in T. dolabrata, exhibits a wide range of biological activities. It inhibits Na+/K+-ATPase and cytochrome P450 (CYP) isoform CYP2B6 with IC50 values of 25.9 µg/ml and Ki of 0.8 µM, respectively. Additionally, thujopsene demonstrates antimicrobial efficacy against both Gram-positive and Gram-negative bacteria, such as S. aureus, M. luteus, and S. typhimurium, with MICs ranging from 25-50 µg/ml. It also suppresses antigen-induced β-hexosaminidase release in IgE-se...
T37810	6',7'-Epoxybergamottin	Others	Others
	6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo...

天然产物

TETRAHYDROPIPERINE

Cat.No: T5786

Synonym: 四氢胡椒碱,Cosmoperine

Target: P450, TRP/TRPV Channel

Cat.No: T1011

Synonym: 伊曲康唑,R51211

Target: P450, Hedgehog/Smoothened, Antibiotic, Autophagy, Antifungal

Cat.No: T6S0923

Synonym: Hypericine,金丝桃素,Cyclosan

Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

Cyperotundone

Cat.No: T5709

Target: Others

alpha-Cyperone

Cat.No: T5S1981

Synonym: (+)-α-Cyperone,α-香附酮,α-Cyperone

Target: Others, Endogenous Metabolite

Cat.No: TN4438

Target: Others

Cypellocarpin C

Cat.No: TN5681

Synonym: Camaldulenside,桉叶苷

Cat.No: T0671

Synonym: Betanaphthol,β-萘酚,乙萘酚

Target: Others, Endogenous Metabolite

Naringin dihydrochalcone

Cat.No: T2761

Synonym: Naringin DC,柚皮苷二氢查尔酮,柚皮甙二氢查尔酮

Target: P450, NF-κB

7-Ethoxycoumarin

Cat.No: T7970

Target: Others

Cat.No: T5594

Target: P450, Antifungal

Cat.No: T2876

Synonym: 2-Phenyl-4-benzopyron,黄酮,2-Phenyl-4-chromone,2-Phenylchromone

Target: NOS, Endogenous Metabolite

5,7-DIMETHOXYFLAVONE

Cat.No: T5778

Target: Anti-infection, P450

Cat.No: T11218

Synonym: epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体

Target: P450

Cat.No: T3S0860

Target: UGT

Cat.No: T5S2343

Synonym: 乙酰紫草素,Acetyl shikonin

Target: Others, P450, AChE

6-Hydroxymelatonin

Cat.No: T13520

Target: Others

Germacrone 4,5-epoxide

Cat.No: TN4130

Target: gp120/CD4, IL Receptor, P450

Cat.No: T82305

5-Hydroxy-8-methoxypsoralen

Cat.No: T40859

Synonym: 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen

Target: Others

Tetrahydro-11-deoxy Cortisol

Cat.No: T36472

Target: Others

Cat.No: TN7505

Synonym: NSC 44707

Target: Others

6',7'-Epoxybergamottin

Cat.No: T37810

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00156	Cyclophilin F Protein, Human, Recombinant (His) peptidylprolyl isomerase F,CYP3,Cyp-D,...	Human	HEK293 Cells
	Cyclophilin F Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A0A024QZS4.
TMPY-01593	Cyclophilin A Protein, Mouse, Recombinant (His) peptidylprolyl isomerase A (cyclophilin A),Cphn,CyP...	Mouse	E. coli
	Cyclophilin A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.8 kDa and the accession number is P17742.
TMPY-03413	PPIL2 Protein, Human, Recombinant (aa 280-457, His) UBOX7,Cyp-60,CYP60,CYC4,peptidylprolyl iso...	Human	E. coli
	PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of pro...
TMPY-06723	Cyp c 1 Protein, Common carp, Recombinant	Common carp	E. coli
	Cyp c 1 Protein, Common carp, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.5 kDa.
TMPY-01380	Cyclophilin B Protein, Human, Recombinant (His) CYPB,peptidylprolyl isomerase B (cyclophilin B),HEL...	Human	HEK293 Cells
	PPIB is identified as a candidate gene for OI-IX. Osteogenesis imperfecta (OI) is an inherited disorder of connective tissue typically caused by defects in either COL1A1 or COL1A2. A number of other genes causative of this disorder have been found, including PPIB, which forms one subunit of the prolyl 3-hydroxylase enzyme complex. Patients with OI caused by PPIB mutation should have appropriate early and regular management of their hearing.
TMPJ-00676	PPIH Protein, Human, Recombinant (His) Peptidyl-Prolyl Cis-Trans Isomerase H,Rotamase H,PPIase H,Sm...	Human	E. coli
	Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the i...
TMPJ-01090	PPID Protein, Human, Recombinant (His) Cyclophilin-40,CYPD,Peptidyl-Prolyl Cis-Trans Isome...	Human	E. coli
	Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.
TMPH-03297	LGALS3BP Protein, Rat, Recombinant (His) Protein 90K,Mac-2-binding protein,Galectin-3-binding protein...	Rat	E. coli
	Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
TMPH-03017	CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) Cytochrome P450-14DM,Sterol 14alpha-demethylase,Sterol 14-al...	Mycobacterium tuberculosis	Baculovirus Insect Cells
	Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
TMPH-02141	CYP21A2 Protein, Human, Recombinant (His) Cytochrome P450 21,CYP21A2,Cytochrome P450-C21B,Cyt...	Human	P. pastoris (Yeast)
	A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
TMPH-02140	CYP21A2 Protein, Human, Recombinant (E. coli, His) Cytochrome P-450c21,Cytochrome P450-C21B,CYP21,21-O...	Human	E. coli
	A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
TMPH-00956	Aromatase/CYP19A1 Protein, Human, Recombinant (His) ARO1,CYP19A1,Estrogen synthase,Cytochrome P450 19A1...	Human	E. coli
	Aromatase/CYP19A1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01184	CYP2A6 Protein, Human, Recombinant (His & Myc) CYP2A3,Coumarin 7-hydroxylase,1,4-cineole 2-exo-mon...	Human	E. coli
	CYP2A6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01182	CYP1A1 Protein, Human, Recombinant (His) Cytochrome P450 1A1,Cytochrome P450-C,Cytochrome P450-P1,Cyt...	Human	E. coli
	CYP1A1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is P04798.
TMPY-05321	CYP3A4 Protein, Human, Recombinant (His) P450C3,P450PCN1,CYPIIIA4,CP34,cytochrome P450 famil...	Human	E. coli
	CYP3A4 is an important member of the cytochrome P450 enzyme superfamily, with 33 allelic variants. Human cytochrome P450 3A4 (CYP3A4) is an important drug metabolizing enzyme involved in a number of drug-drug and food-drug interactions. Systemic inflammation has been linked to suppressed CYP3A4 activity.
TMPH-02139	CYP17A1 Protein, Human, Recombinant (GST) Cytochrome P450 17A1,CYPXVII,CYP17A1,C...	Human	E. coli
	A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol (Probable). Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, follow...
TMPH-01185	CYP2C19 Protein, Human, Recombinant (His & Myc) Cytochrome P450 2C19,(R)-limonene 6-monooxygenase,(S)-limone...	Human	E. coli
	CYP2C19 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPJ-01389	PPIE Protein, Human, Recombinant (His) Rotamase E,PPIE,Cyclophilin E,PPIase E,CYP33,Cyclop...	Human	E. coli
	Peptidyl-prolyl cis-trans isomerase E, also known as Cyclophilin E, Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which belongs to the cyclophilin-type PPIase family of PPIase E subfamily. PPIE found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. PPIE contains one PPIase cyclophilin-type domain and one RRM (RNA recognition motif) domain. PPIE accelerates the folding of proteins. It catalyzes the cis-trans isomerization of ...
TMPH-01084	CYP11A1 Protein, Human, Recombinant (His & SUMO) Cholesterol side-chain cleavage enzyme, mitochondrial,CY...	Human	E. coli
	CYP11A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.1 kDa and the accession number is P05108.
TMPH-01183	CYP26B1 Protein, Human, Recombinant (His) Cytochrome P450 26A2,CYP26B1,P450RAI2,Cytochrome P4...	Human	E. coli
	CYP26B1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.5 kDa and the accession number is Q9NR63.
TMPH-02618	CYP2E1 Protein, Mouse, Recombinant (His) Cyp2e1,Cytochrome P450 2E1,Cytochrome P450-J,4-nitr...	Mouse	E. coli
	A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be invo...
TMPH-01181	CYP11B2 Protein, Human, Recombinant (His & SUMO) ALDOS,Corticosterone 18-monooxygenase, CYP11B2,Aldo...	Human	E. coli
	CYP11B2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01186	CYP2C9 Protein, Human, Recombinant (His & Myc) CYP2C10,Cytochrome P450 2C9,S-mephenytoin 4-hydroxy...	Human	E. coli
	CYP2C9 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-02180	CXCL1 Protein, Human, Recombinant (His & NusA) CA21H,CPS1,CYP21,GRO1,GROa,SCYB1,NAP-3,MGSA-a,P450c...	Human	E. coli
	CXCL1 Protein, Human, Recombinant (His & NusA) is expressed in E. coli expression system with His and NusA tag. The predicted molecular weight is 65 kDa and the accession number is P09341-1.
TMPY-02026	CXCL1 Protein, Human, Recombinant (His & SUMO) FSP,P450c21B,CYP21B,CAH1,GROa,SCYB1,MGSA,chemokine ...	Human	E. coli
	CXCL1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with His and SUMO tag. The predicted molecular weight is 21.3 kDa and the accession number is P09341-1.
TMPY-02868	CXCL1 Protein, Human, Recombinant chemokine (C-X-C motif) ligand 1 (melanoma growth stimulatin...	Human	E. coli
	CXCL1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is P09341-1.
TMPY-02297	ACYP1 Protein, Human, Recombinant (GST) ACYPE,acylphosphatase 1, erythrocyte (common) type	Human	E. coli
	ACYP1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 38 kDa and the accession number is P07311.
TMPY-02298	ACYP2 Protein, Human, Recombinant (GST) ACYM,acylphosphatase 2, muscle type,ACYP	Human	E. coli
	Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to cisplatin-induced ototoxicity in patients with testicular cancer. Telomere length, as a marker of biological aging, has been reported to influence the risk of several age-related diseases, including ischemic stroke. Recent studies have identified the genetic variant within ACYP2 a...
TMPH-00364	Pectate lyase 1 Protein, Chamaecyparis obtusa, Recombinant (His & SUMO) Major pollen allergen Cha o 1,Pectate lyase 1	Chamaecyparis obtusa	E. coli
	Has pectate lyase activity. Pectate lyase 1 Protein, Chamaecyparis obtusa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the accession number is Q96385.
TMPJ-00048	CYPA Protein, Mouse, Recombinant SP18,PPIA,PPIase A,Peptidyl-prolyl cis-trans isomerase A,	Mouse	E. coli
	Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins(CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopep...
TMPJ-00798	ACYP1 Protein, Human, Recombinant (His) ACYPE,Acylphosphate phosphohydrolase 1,erythrocyte ...	Human	E. coli
	ACYP1, also known as Acylphosphatase-1, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, organ-common type isozyme, Acylphosphate phosphohydrolase 1 and ACYPE, is a small cytosolic enzyme which catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates.ACYP1 is a protein which belongs to the acylphosphatase family and contains 1 fibrinogen C-terminal domain. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase, on the basis of thei...
TMPJ-01049	CYPA Protein, Human, Recombinant Rotamase A,Peptidyl-prolyl cis-trans isomerase A,PPIase A,PP...	Human	E. coli
	Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressi...
TMPH-01748	CYPOR Protein, Human, Recombinant (GST) NADPH--cytochrome P450 reductase,P450R,CPR,POR,CYPO...	Human	E. coli
	This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. CYPOR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 102.9 kDa and the accession number is P16435.
TMPH-00817	Pectate lyase 1 Protein, Hesperocyparis arizonica, Recombinant (His & Myc) Major pollen allergen Cup a 1,Pectate lyase 1	Hesperocyparis arizonica	E. coli
	Has pectate lyase activity. Pectate lyase 1 Protein, Hesperocyparis arizonica, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 42.6 kDa and the accession number is Q9SCG9.
TMPH-02801	CYPOR Protein, Mouse, Recombinant (His) CYPOR,P450R,CPR,NADPH--cytochrome P450 reductase,PO...	Mouse	E. coli
	CYPOR Protein, Mouse, Recombinant (His) is expressed in E. coli.

重组蛋白

Cyclophilin F Protein, Human, Recombinant (His)

Cat.No: TMPY-00156

Species: Human

Expression System: HEK293 Cells

Cyclophilin A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01593

Species: Mouse

Expression System: E. coli

PPIL2 Protein, Human, Recombinant (aa 280-457, His)

Cat.No: TMPY-03413

Species: Human

Expression System: E. coli

Cyp c 1 Protein, Common carp, Recombinant

Cat.No: TMPY-06723

Species: Common carp

Expression System: E. coli

Cyclophilin B Protein, Human, Recombinant (His)

Cat.No: TMPY-01380

Species: Human

Expression System: HEK293 Cells

PPIH Protein, Human, Recombinant (His)

Cat.No: TMPJ-00676

Species: Human

Expression System: E. coli

PPID Protein, Human, Recombinant (His)

Cat.No: TMPJ-01090

Species: Human

Expression System: E. coli

LGALS3BP Protein, Rat, Recombinant (His)

Cat.No: TMPH-03297

Species: Rat

Expression System: E. coli

CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)

Cat.No: TMPH-03017

Species: Mycobacterium tuberculosis

Expression System: Baculovirus Insect Cells

CYP21A2 Protein, Human, Recombinant (His)

Cat.No: TMPH-02141

Species: Human

Expression System: P. pastoris (Yeast)

CYP21A2 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02140

Species: Human

Expression System: E. coli

Aromatase/CYP19A1 Protein, Human, Recombinant (His)

Cat.No: TMPH-00956

Species: Human

Expression System: E. coli

CYP2A6 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01184

Species: Human

Expression System: E. coli

CYP1A1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01182

Species: Human

Expression System: E. coli

CYP3A4 Protein, Human, Recombinant (His)

Cat.No: TMPY-05321

Species: Human

Expression System: E. coli

CYP17A1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02139

Species: Human

Expression System: E. coli

CYP2C19 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01185

Species: Human

Expression System: E. coli

PPIE Protein, Human, Recombinant (His)

Cat.No: TMPJ-01389

Species: Human

Expression System: E. coli

CYP11A1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01084

Species: Human

Expression System: E. coli

CYP26B1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01183

Species: Human

Expression System: E. coli

CYP2E1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02618

Species: Mouse

Expression System: E. coli

CYP11B2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01181

Species: Human

Expression System: E. coli

CYP2C9 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01186

Species: Human

Expression System: E. coli

CXCL1 Protein, Human, Recombinant (His & NusA)

Cat.No: TMPY-02180

Species: Human

Expression System: E. coli

CXCL1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPY-02026

Species: Human

Expression System: E. coli

CXCL1 Protein, Human, Recombinant

Cat.No: TMPY-02868

Species: Human

Expression System: E. coli

ACYP1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02297

Species: Human

Expression System: E. coli

ACYP2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02298

Species: Human

Expression System: E. coli

Pectate lyase 1 Protein, Chamaecyparis obtusa, Recombinant (His & SUMO)

Cat.No: TMPH-00364

Species: Chamaecyparis obtusa

Expression System: E. coli

CYPA Protein, Mouse, Recombinant

Cat.No: TMPJ-00048

Species: Mouse

Expression System: E. coli

ACYP1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00798

Species: Human

Expression System: E. coli

CYPA Protein, Human, Recombinant

Cat.No: TMPJ-01049

Species: Human

Expression System: E. coli

CYPOR Protein, Human, Recombinant (GST)

Cat.No: TMPH-01748

Species: Human

Expression System: E. coli

Pectate lyase 1 Protein, Hesperocyparis arizonica, Recombinant (His & Myc)

Cat.No: TMPH-00817

Species: Hesperocyparis arizonica

Expression System: E. coli

CYPOR Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02801

Species: Mouse

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0464	trans-Cypermethrin-d6 (dimethyl-d6)
	trans-Cypermethrin-d6 (dimethyl-d6) 是 trans-Cypermethrin 的氘代化合物。trans-Cypermethrin 的 CAS 号为 67375-30-8。alpha-Cypermethrin 是一种合成拟除虫菊酯杀虫剂，用于大规模商业农业应用。
T12701	(rel)-Tranylcypromine D5 hydrochloride 2-Phenylcyclopropylamine D5 hydrochloride	Histone Demethylase	Chromatin/Epigenetic
	(rel)-Tranylcypromine D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective inhibitor of monoamine oxidase (MAO) used in the treatment of depression.
TMIJ-0358	2-Naphthol-d8
	2-Naphthol-d8 是 2-Naphthol 的氘代化合物。2-Naphthol 的 CAS 号为 135-19-3。2-Naphthol 是一种 naphthalene 的代谢物，由细胞色素 P450 亚型 (CYP 1A1，CYP 1A2，CYP 2A1，CYP 2E1 和 CYP 2F2) 催化而成。2-Naphthol 具有细胞毒性。
T71302	Norfluoxetine-d5 HCl
	Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa...
T69758	Flutamide-d7
	Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. It is cytotoxic to PC3 and LNCaP prostate cancer cells with IC50 values of 98.8 and 81.8 µM, respectively. Flutamide (50 mg/kg per day) reduces tumor growth in a PC-82 mouse xenograft mo...
TMID-0116	Carbamazepine-10,11-epoxide-d10 (rings-d10)
	Carbamazepine-10,11-epoxide-d10 (rings-d10) 是 Carbamazepine-10,11-epoxide 的氘代化合物。Carbamazepine-10,11-epoxide 的 CAS 号为 36507-30-9。Carbamazepine 10,11-epoxide是抗惊厥药卡马西平 (carbamazepine) 的活性代谢物。它由卡马西平通过微粒体中的细胞色素 P450 (CYP) 同种型 CYP3A4 和 CYP2C8 形成，微粒体分别由表达 CYP3A4 或 CYP2C8 的 HepG2 细胞制备。它对小鼠最大电击诱发的癫痫发作具有抗惊厥活性。
T71327	Paraxanthine-d6
	Paraxanthine-d6 is intended for use as an internal standard for the quantification of paraxanthine by GC- or LC-MS. Paraxanthine is an active metabolite of caffeine. It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist. In vivo, paraxanthine increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by the adenosine A1 agoni...

同位素标记化合物

trans-Cypermethrin-d6 (dimethyl-d6)

Cat.No: TMIJ-0464

(rel)-Tranylcypromine D5 hydrochloride

Cat.No: T12701

Synonym: 2-Phenylcyclopropylamine D5 hydrochloride

Target: Histone Demethylase

Cat.No: TMIJ-0358

Norfluoxetine-d5 HCl

Cat.No: T71302

Cat.No: T69758

Carbamazepine-10,11-epoxide-d10 (rings-d10)

Cat.No: TMID-0116

Paraxanthine-d6

Cat.No: T71327

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