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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9694 |
Emraclidine
CVL-231 |
AChR | Neuroscience |
Emraclidine (CVL-231) 是一种毒蕈碱 M4 受体阳性变构调节剂,可用于神经系统疾病研究。 | |||
T16999 |
Tavapadon
PF-6649751,CVL-751 |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Tavapadon (CVL-751) 是一种具有口服活性,高选择性的多巴胺 D1/D5受体部分激动剂,它可有效促进运动并减少残疾,对帕金森氏病具有潜在的应用价值。 | |||
T16489 |
Darigabat
CVL-865,PF-6372865,PF-06372865 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Darigabat (PF-06372865) 是一种可穿过血脑屏障且具有口服活性和选择性的 GABAA 受体调节剂,具有抗焦虑活性,对 α2、α1 PAM、α2 PAM 的 Ki 值分别为 2.9 nM、21 nM、134 nM。Darigabat 可用于研究焦虑症和癫痫。 | |||
T70783 |
Azo-Resveratrol
|
Others | Others |
Azo-Resveratrol is an analog of Resveratrol used as a potent tyrosinase inhibitor. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03053 |
Ezrin Protein, Human, Recombinant (His)
HEL-S-105,CVL,VIL2,CVIL,ezrin |
Human | E. coli |
VIL2, also known as villin-2, belongs to the ERM protein family. It is expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. VIL2 contains 1 FERM domain and may be involved in connections of major cytoskel |