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Search Results for " csf1r "
Targets Recommended: c-Fms

56

抑制剂 & 化合物

22

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T10894 CSF1R-IN-1

c-Fms Tyrosine Kinase/Adaptors
CSF1R-IN-1 是一种 CSF1R 抑制剂 (IC50:0.5 nM)。
T13194 CSF1R-IN-2

c-Fms; c-Met/HGFR; Src Angiogenesis; Tyrosine Kinase/Adaptors
CSF1R-IN-2 是一种口服具有活力的、有效的 SRC,MET 和 c-FMS 抑制剂,它们的 IC50 值分别为 0.12 nM,0.14 nM 和 0.76 nM。
T64066 CSF1R-IN-3

c-Fms; CSF-1R Tyrosine Kinase/Adaptors
CSF1R-IN-3是一种口服有效的 CSF-1R 抑制剂,IC50值为2.1nM。CSF1R-IN-3对结直肠癌细胞具有抗增殖活性。CSF1R-IN-3 通过抑制巨噬细胞的迁移,诱导 M2 型巨噬细胞重新编程为 M1 型巨噬细胞,从而表现出抗肿瘤作用和提高免疫力的作用,展现对结直肠癌细胞的活性。
T62313 CSF1R-IN-10

Others Others
CSF1R-IN-10 (Compound 48) 是一种 CSF-1R 抑制剂 (IC50: 0.005 μM)。
T61893 CSF1R-IN-12

Others Others
CSF1R-IN-12 是一种有效的集落刺激因子1受体 CSF1R 抑制剂。CSF1R-IN-12 在癌症疾病中具有研究潜力。
T62190 CSF1R-IN-7

Others Others
CSF1R-IN-7 (Formula I) 是一种 CSF-1R 抑制剂,能够用于研究阿尔兹海默症。
T62364 CSF1R-IN-5

Others Others
CSF1R-IN-5 是一种 CSF1R 的有效抑制剂。其中 CSF-1R 表达于巨噬细胞中,巨噬细胞的存活和分化依赖于 CSF-1/CSF-1R 信号通路。CSF1R-IN-5 可以影响 TAM 和胶质瘤细胞之间炎症因子的交换。CSF1R-IN-5 具有潜力进行癌症疾病的研究。
T62318 CSF1R-IN-9

Others Others
CSF1R-IN-9 (Compound 46) 是一种 CSF-1R 抑制剂 (IC50: 0.028 μM)。
T79472 CSF1R-IN-17

c-Fms Tyrosine Kinase/Adaptors
CSF1R-IN-17(compound 9)是一种选择性高的CSF1R拮抗剂,表现出0.2 nM的低IC50值,并能有效抑制破骨细胞的分化。
T62390 CSF1R-IN-8

Others Others
CSF1R-IN-8 (Compound 22) 是一种 CSF-1R 抑制剂 (IC50: 0.012 μM)。
T62187 CSF1R-IN-6

Others Others
CSF1R-IN-6 是一种 CSF1R 的有效抑制剂。其中 CSF-1R 表达于巨噬细胞中,巨噬细胞的存活和分化依赖于 CSF-1/CSF-1R 信号通路。CSF1R-IN-6 能够影响 TAM 和胶质瘤细胞之间炎症因子的交换。CSF1R-IN-6 对癌症疾病表现出潜在的研究价值。
T61554 CSF1R-IN-13

Others Others
CSF1R-IN-13 is a powerful CSF1R inhibitor with potential applications in researching cancer diseases [1]. CSF1R, also known as colony stimulating factor 1 receptor, is a critical growth factor that regulates various cell types, including bone marrow progenitor cells, monocytes, macrophages, and giants [1]. CSF1R-IN-13 shows promise in furthering our understanding of cancer-related disorders (WO2019134661A1, compound 32) [1].
T62557 CSF1R-IN-14

Others Others
CSF1R-IN-14 是一种异吲哚啉酮衍生物化合物,是一种 CSF1R 的有效抑制剂。其中集落刺激因子1 (CSF-1,又称巨噬细胞集落刺激因子,M-CSF) 是一种控制骨髓祖细胞、单核细胞、巨噬细胞和巨噬细胞的重要生长因子。CSF1R-IN-14 具有潜力进行癌症疾病的研究。
T62342 CSF1R-IN-4

Others Others
CSF1R-IN-4 是一种 CSF-1R 的有效抑制剂。其中 CSF-1R 表达于巨噬细胞中,巨噬细胞的存活和分化依赖于 CSF-1/CSF-1R 信号通路。CSF1R-IN-4 能够影响 TAM 和胶质瘤细胞之间炎症因子的交换。CSF1R-IN-4 具有潜力进行癌症疾病的研究。
T72574 Axl/Mer/CSF1R-IN-1

Others Others
Axl/Mer-IN-1 是一种 Axl/Mer 受体酪氨酸激酶 (Axl/Mer RTK) 和CSF1R 抑制剂,Kd 值均小于 0.1 μM。
T6119 Sotuletinib

BLZ945

c-Fms; CSF-1R Tyrosine Kinase/Adaptors
Sotuletinib (BLZ945) 是一种选择性的、有效的、脑渗透性的CSF-1R (c-Fms)抑制剂 (IC50:1 nM),选择性是其他受体酪氨酸激酶同系物的 1000 倍。
T14380 AZD7507

CSF-1R; HER; Sodium Channel Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
AZD7507 是口服具有活力的CSF-1R 抑制剂,具有抗肿瘤作用。
T5586 cFMS Receptor Inhibitor II

c-Fms Tyrosine Kinase/Adaptors
cFMS Receptor Inhibitor II 是 CSF-1R 激酶抑制剂。其中 CSF-1 是细胞因子。
TQ0015 PRN1371

c-Fms; FGFR; CSF-1R Angiogenesis; Tyrosine Kinase/Adaptors
PRN1371 是一种高效的、选择性的FGFR1-4和CSF1R 抑制剂,对FGFR1,FGFR2,FGFR3,FGFR4 和 CSF1R 的IC50值分别为 0.6,1.3,4.1,19.3 和 8.1 nM。
T7100 PLX5622

PLX-5622

c-Fms; CSF-1R Tyrosine Kinase/Adaptors
PLX5622 是一种选择性的、高效的、能透过血脑屏障的、口服具有活性的 CSF1R 抑制剂 (IC50= 0.016 µM;Ki= 5.9 nM),具有较好的药理学特性,可用于病程发展前和过程中,扩大的和特异性的小胶质细胞的消除。
T2659 GW2580

GW 2580,SC-203877

c-Fms Tyrosine Kinase/Adaptors
GW2580 (SC-203877) 是一种口服有效的、选择性的 c-Fms 激酶抑制剂,体外实验中在 0.06 μM 时可完全抑制人 cFMS 激酶。它是 ATP 与 cFMS 激酶结合的竞争性抑制剂,能够抑制集落刺激因子 1 信号传导。
T10652 Vimseltinib

DCC-3014

c-Fms; CSF-1R; c-Kit Tyrosine Kinase/Adaptors
Vimseltinib (DCC-3014) 是 c-FMS(CSF-IR) 和 c-Kit 抑制剂,IC50值分别为 <0.01 μM 和 0.1-1 μM。
T2115 Pexidartinib

PLX-3397

Apoptosis; c-Fms; FLT; CSF-1R; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Pexidartinib (PLX-3397) 是一种 CSF-1R 和 c-Kit 的抑制剂 (IC50=20/10 nM),具有选择性、ATP 竞争性和口服活性。Pexidartinib 具有抗肿瘤活性,可以诱导细胞凋亡。
T2624 OSI-930

OSI 930,噻尔非尼

Apoptosis; c-Fms; Raf; VEGFR; FLT; CSF-1R; Src; c-Kit Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
OSI-930 是 Kit,KDR 和 CSF-1R (c-Fms)的口服选择性抑制剂,IC50分别为 80 nM,9 nM 和 15 nM。它具有抗肿瘤活性,靶向肿瘤中的癌细胞增殖和血管生成。它还适度抑制 Flt-1,c-Raf 和 Lck,并且对 PDGFRα/β,Flt-3和 Abl 具有较弱的抑制活性。
T35570 Chiauranib

CS2164,西奥罗尼

c-Fms; VEGFR; FLT; PDGFR; c-Kit; Aurora Kinase Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
Chiauranib 是一种针对肿瘤血管生成的多靶点抑制剂,具有强大的抗癌作用。 Chiauranib 有效抑制血管生成相关激酶(VEGFR1、VEGFR2、VEGFR3、PDGFRα 和 c-Kit)、有丝分裂相关激酶 Aurora B 和慢性炎症相关激酶 CSF1R,IC50 值范围为 1-9 nM。
T15199 Edicotinib

JNJ-527,JNJ-40346527

c-Fms; FLT; CSF-1R; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Edicotinib (JNJ-527) 是能够透过血脑屏障的、口服具有活性的、选择性的CSF-1R 抑制剂 (IC50:3.2 nM)。它对 KIT (IC50:20 nM) 和 FLT3 (IC50:190 nM) 的抑制作用较小。它抑制小胶质细胞的扩张,减弱小胶质细胞的增殖和神经退行性变。它可用于研究阿尔茨海默病和类风湿性关节炎。
T4315 Ki20227

N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲

c-Fms; VEGFR; CSF-1R; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Ki20227 是一种高效的、口服具有活性的、选择性的CSF1R(c-Fms 酪氨酸激酶)抑制剂,对 CSF1R,VEGFR2,c-Kit 和PDGFRβ的IC50分别为 2 nM,12 nM,451 nM 和 217 nM。它可以阻止破骨细胞分化和溶骨性破坏。
T6930 Pazopanib Hydrochloride

GW786034,Pazopanib HCl,GW786034 HCl,盐酸帕唑帕尼,Votrient HCl,Armala

c-Fms; VEGFR; FGFR; PDGFR; c-Kit; Autophagy Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
Pazopanib Hydrochloride (Votrient HCl) 是一种多靶点抑制剂,抑制 VEGFR1、VEGFR2、VEGFR3、PDGFRβ、c-Kit、FGFR1和c-Fms 的IC50分别为10、30、47、84、74、140和146 nM。
T6289 Dovitinib

TKI258,多韦替尼,CHIR-258,度维替尼

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib (CHIR-258) 是一种口服有效的、多靶点的酪氨酸激酶 (RTK) 抑制剂,具有抗肿瘤作用。
T6028 PF 477736

PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

c-Fms; VEGFR; FGFR; FLT; c-RET; Chk; CDK; Src; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
PF 477736 (PF-736,PF-00477736) 是一种特异性、有效且具有 ATP 竞争性的 Chk1 抑制剂,Ki 值为0.49 nM。它也是Chk2抑制剂,Ki 值为 47 nM。它还抑制VEGFR2、Fms、Yes、Aurora-A、FGFR3、Flt3和Ret。
T2514 Linifanib

利尼伐尼,ABT-869,RG3635,AL-39324

Apoptosis; c-Fms; VEGFR; FLT; CSF-1R; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors
Linifanib (AL-39324) 是一种高效口服的VEGFR 和PDGFR 家族多靶点抑制剂,具有显著的抗肿瘤活性。它对无关 RTKs、可溶性酪氨酸激酶或丝氨酸/苏氨酸激酶的活性要低得多。它是特异性 miR-10b 抑制剂,阻断miR-10b 的生物合成。
T1925 PLX647

c-Fms; c-Kit Tyrosine Kinase/Adaptors
PLX647 是具有口服活性的、高效的、特异性的FMS 和KIT 双激酶抑制剂,IC50分别为 28 和 16 nM。它 (1 μM) 在 400 个激酶组中显示出对 FMS 和 KIT 有选择性,但 FLT3 和 KDR 除外 (IC50=91 和 130 nM)。
T79157 Pimicotinib

ABSK021,ABSK-021

c-Fms; Others Others; Tyrosine Kinase/Adaptors
Pimicotinib (ABSK021) 为一种有效的 CSF1R 抑制剂,具抗肿瘤活性,可用于研究晚期实体瘤。
TQ0235 AC710

FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
AC710是一种 PDGFR 抑制剂,能够作用于 FLT3 (Kd:0.6),CSF1R (Kd:1.57),KIT (Kd:1),PDGFRα (Kd:1.3) 和 PDGFRβ (Kd:1.0)。
T4075 Sulfatinib

KDR-IN-1,索凡替尼

VEGFR; FGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Sulfatinib (KDR-IN-1) (HMPL-012) 是一种有效且高度选择性的酪氨酸激酶抑制剂,可抑制VEGFR1/2/3,FGFR1和CSF1R,IC50范围为1 到 24 nM 之间。
T76776 Emactuzumab

RO 5509554,RG 7155

c-Fms; TAM Receptor Tyrosine Kinase/Adaptors
Emactuzumab(RG 7155) 是一种针对集落刺激因子-1 受体的单克隆抗体,靶向肿瘤相关巨噬细胞 (TAM)。Emactuzumab 具有抗肿瘤活性,可抑制集落刺激因子 1 受体 (CSF1R) 的激活。Emactuzumab 对 CSF-1R 具有高亲和力,Ki 值为 0.2 nM。Emactuzumab 可阻断 CSF-1R 二聚化,可用于研究如弥漫型腱鞘巨细胞瘤(dt-GCT)类的癌症。
T5172 AZ304

c-Fms; Raf; p38 MAPK; Autophagy Autophagy; MAPK; Tyrosine Kinase/Adaptors
AZ304 是一种 ATP 竞争性双 BRAF 激酶抑制剂,有效抑制 BRAF (WT)、BRAF (V600E) 和野生型 CRAF,IC50值分别为79、38和68 nM。具有抗肿瘤活性。它对 p38 和 CSF1R 也有抑制作用,IC50值分别为 6 nM 和 35 nM。
T4376 Nampt-IN-1

LSN3154567

c-Fms; NAMPT; CSF-1R Metabolism; Tyrosine Kinase/Adaptors
Nampt-IN-1 (LSN3154567) 是选择性的 NAMPT 抑制剂,能够抑制纯化的 NAMPT,IC50=3.1 nM。
T35333 ARRY-382

CSF-1R Tyrosine Kinase/Adaptors
ARRY-382 是一种高度选择性的 CSF-1R 口服抑制剂,IC50 为 9 nM。
T11729 JTE-952

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
JTE-952 is a oral, potent active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse
T40164 BPR1R024

BPR1R024

Others Others
BPR1R024 is an orally active and selective CSF1R inhibitor ( IC 50 = 0.53 nM).
T10228 AC710 Mesylate

PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
AC710 Mesylate is a potent PDGFR inhibitor (Kds: 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ).
T21330 JNJ-28312141

JNJ 28312141,JNJ28312141

Others Others
JNJ-28312141 is an orally active CSF1R inhibitor and a FLT3 inhibitor. JNJ-28312141 is a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth a
T29542 AC708

AC 708,AC-708

Others Others
AC708 is a small molecule CSF1R inhibitor that effectively inhibits CSF1R phosphorylation mediated by CSF-1 (IC50 = 26 nM) and IL-34 (IC50 = 33 nM). It also inhibited the activity of growth factor-dependent cells cultured in CSF-1 (IC50 = 38 nM) or IL-34
T12505 PLX5622 hemifumarate

c-Fms Tyrosine Kinase/Adaptors
PLX5622 hemifumarate 是高度选择性的、能透过血脑屏障的、具有口服活性的 CSF1R 抑制剂,IC50值为 0.016 μM,Ki 值为 5.9 nM,可用于病程发展前和过程中,扩大和特异性的小胶质细胞的消除。PLX5622 hemifumarate 具有较理想的药代动力学特性。
T69759 IACS-9439

c-Fms Tyrosine Kinase/Adaptors
IACS-9439是一种CSF1R抑制剂,具有高效、选择性和口服活性,Ki值仅为1 nM。适用于研究晚期实体肿瘤。
T62788 Pexidartinib hydrochloride

Others Others
Pexidartinib hydrochloride (PLX-3397 hydrochloride) 是一种有效的、选择性的、口服具有活力的、ATP-竞争性的集落刺激因子 1 (CSF1R 或 M-CSFR) (IC50: 20 nM) 和 c-Kit (IC50: 10 nM) 抑制剂。Pexidartinib hydrochloride 对 c-Kit 和 CSF1R 的选择性是对其他相关激酶的 10-100 倍,作用于 FLT3 (IC50: 160 nM)、KDR (VEGFR2) (IC50: 350 nM)、LCK (IC50: 860 nM)、FLT1 (VEGFR1) (IC50: 880 nM) 和 NTRK3 (TRKC) (IC50: 890 nM)。Pexidartinib hydrochloride 能够诱导细胞凋亡,表现出抗肿瘤作用。
T76786 Cabiralizumab

Cabiralizumab (FPA 008) 是一种抗 CSF1R 单克隆抗体 (MAb)。Cabiralizumab 可增强 T 细胞浸润和抗肿瘤 T 细胞免疫反应。Cabiralizumab 抑制破骨细胞的活化并阻止骨质破坏,可用于类风湿性关节炎 (RA) 的研究。Cabiralizumab 可与 Nivolumab 结合用于肺癌研究。
T70444 Edicotinib HCl

Others Others
Edicotinib, also known as JNJ-40346527, is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity. FMS tyrosine kinase inhibitor JNJ-40346527 blocks the receptor-ligand interaction between FMS and its ligand CSF1, thereby preventing autophosphorylation of FMS. As a result, unphosphorylated FMS cannot activate FMS-mediated signaling pathways, thus potentially inhibiting cell proliferation in FMS-overexpressed tum...
T71400 Quizartinib HCl

Others Others
Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro...

化合物

CSF1R-IN-1
Cat.No: T10894
Synonym:
Target: c-Fms
CSF1R-IN-2
Cat.No: T13194
Synonym:
Target: c-Fms, c-Met/HGFR, Src
CSF1R-IN-3
Cat.No: T64066
Synonym:
Target: c-Fms, CSF-1R
CSF1R-IN-10
Cat.No: T62313
Synonym:
Target: Others
CSF1R-IN-12
Cat.No: T61893
Synonym:
Target: Others
CSF1R-IN-7
Cat.No: T62190
Synonym:
Target: Others
CSF1R-IN-5
Cat.No: T62364
Synonym:
Target: Others
CSF1R-IN-9
Cat.No: T62318
Synonym:
Target: Others
CSF1R-IN-17
Cat.No: T79472
Synonym:
Target: c-Fms
CSF1R-IN-8
Cat.No: T62390
Synonym:
Target: Others
CSF1R-IN-6
Cat.No: T62187
Synonym:
Target: Others
CSF1R-IN-13
Cat.No: T61554
Synonym:
Target: Others
CSF1R-IN-14
Cat.No: T62557
Synonym:
Target: Others
CSF1R-IN-4
Cat.No: T62342
Synonym:
Target: Others
Axl/Mer/CSF1R-IN-1
Cat.No: T72574
Synonym:
Target: Others
Sotuletinib
Cat.No: T6119
Synonym: BLZ945
Target: c-Fms, CSF-1R
AZD7507
Cat.No: T14380
Synonym:
Target: CSF-1R, HER, Sodium Channel
cFMS Receptor Inhibitor II
Cat.No: T5586
Synonym:
Target: c-Fms
PRN1371
Cat.No: TQ0015
Synonym:
Target: c-Fms, FGFR, CSF-1R
PLX5622
Cat.No: T7100
Synonym: PLX-5622
Target: c-Fms, CSF-1R
GW2580
Cat.No: T2659
Synonym: GW 2580,SC-203877
Target: c-Fms
Vimseltinib
Cat.No: T10652
Synonym: DCC-3014
Target: c-Fms, CSF-1R, c-Kit
Pexidartinib
Cat.No: T2115
Synonym: PLX-3397
Target: Apoptosis, c-Fms, FLT, CSF-1R, c-Kit
OSI-930
Cat.No: T2624
Synonym: OSI 930,噻尔非尼
Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit
Chiauranib
Cat.No: T35570
Synonym: CS2164,西奥罗尼
Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase
Edicotinib
Cat.No: T15199
Synonym: JNJ-527,JNJ-40346527
Target: c-Fms, FLT, CSF-1R, c-Kit
Ki20227
Cat.No: T4315
Synonym: N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲
Target: c-Fms, VEGFR, CSF-1R, PDGFR, c-Kit
Pazopanib Hydrochloride
Cat.No: T6930
Synonym: GW786034,Pazopanib HCl,GW786034 HCl,盐酸帕唑帕尼,Votrient HCl,Armala
Target: c-Fms, VEGFR, FGFR, PDGFR, c-Kit, Autophagy
Dovitinib
Cat.No: T6289
Synonym: TKI258,多韦替尼,CHIR-258,度维替尼
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
PF 477736
Cat.No: T6028
Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736
Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase
Linifanib
Cat.No: T2514
Synonym: 利尼伐尼,ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
PLX647
Cat.No: T1925
Synonym:
Target: c-Fms, c-Kit
Pimicotinib
Cat.No: T79157
Synonym: ABSK021,ABSK-021
Target: c-Fms, Others
AC710
Cat.No: TQ0235
Synonym:
Target: FLT, PDGFR, c-Kit
Sulfatinib
Cat.No: T4075
Synonym: KDR-IN-1,索凡替尼
Target: VEGFR, FGFR, HER
Emactuzumab
Cat.No: T76776
Synonym: RO 5509554,RG 7155
Target: c-Fms, TAM Receptor
AZ304
Cat.No: T5172
Synonym:
Target: c-Fms, Raf, p38 MAPK, Autophagy
Nampt-IN-1
Cat.No: T4376
Synonym: LSN3154567
Target: c-Fms, NAMPT, CSF-1R
ARRY-382
Cat.No: T35333
Synonym:
Target: CSF-1R
JTE-952
Cat.No: T11729
Synonym:
Target: Histamine Receptor
BPR1R024
Cat.No: T40164
Synonym: BPR1R024
Target: Others
AC710 Mesylate
Cat.No: T10228
Synonym:
Target: PDGFR
JNJ-28312141
Cat.No: T21330
Synonym: JNJ 28312141,JNJ28312141
Target: Others
AC708
Cat.No: T29542
Synonym: AC 708,AC-708
Target: Others
PLX5622 hemifumarate
Cat.No: T12505
Synonym:
Target: c-Fms
IACS-9439
Cat.No: T69759
Synonym:
Target: c-Fms
Pexidartinib hydrochloride
Cat.No: T62788
Synonym:
Target: Others
Cabiralizumab
Cat.No: T76786
Synonym:
Target:
Edicotinib HCl
Cat.No: T70444
Synonym:
Target: Others
Quizartinib HCl
Cat.No: T71400
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-01419 CSF1R Protein, Cynomolgus, Recombinant (His)

CSF-1-R,CSF-1 receptor,Proto-oncogene c-Fm...

Cynomolgus HEK293 Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ...
TMPJ-01418 CSF1R Protein, Cynomolgus, Recombinant (hFc)

M-CSF-R,CSF1R,CSF-1-R,

Cynomolgus HEK293 Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ...
TMPH-00354 CSF1R Protein, Feline, Recombinant (His & SUMO)

FMS,M-CSF-R,CSF-1-R,CSF1R

Feline E. coli
CSF1R Protein, Feline, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 70.8 kDa and the accession number is P13369.
TMPY-01037 CSF1R Protein (Met1-Glu512), Human, Recombinant (His)

CSF-1R,CD115,HDLS,FIM2,M-CSF-R,M<...

Human HEK293 Cells
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is P07333-1.
TMPK-00415 M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated

CSF-1-R,M-CSF R,C-FMS,FMSFIM2,CSF...

Human HEK293 Cells
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 57.4 kDa and the accession number is P07333-1.
TMPK-00656 M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His)

M-CSF R,M-CSFR,HDLS,C-FMS,CSF...

Cynomolgus HEK293 Cells
M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 56.3 kDa and the accession number is G7P8P1.
TMPK-00414 M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi)

FMSFIM2,FMS,M-CSF R,HDLS,M-CSFR,CSF

Human HEK293 Cells
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 57.4 kDa and the accession number is P07333-1.
TMPY-00881 CSF1R Protein, Human, Recombinant

FIM2,C-FMS,CD115,CSFR,MCSF Receptor,FMS,

Human HEK293 Cells
CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.
TMPY-05436 CSF1R Protein, Mouse, Recombinant (hFc)

AI323359,Csfmr,Fim-2,Fms,colony stimulating factor ...

Mouse HEK293 Cells
CSF1R Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.9 kDa and the accession number is P09581.
TMPY-03734 CSF1R Protein, Rat, Recombinant (His)

colony stimulating factor 1 receptor

Rat HEK293 Cells
CSF1R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.5 kDa and the accession number is D4ACA7.
TMPY-03920 CSF1R Protein, Rat, Recombinant (hFc)

colony stimulating factor 1 receptor

Rat HEK293 Cells
CSF1R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is D4ACA7.
TMPY-05040 CSF1R Protein, Rhesus, Recombinant (His)

colony stimulating factor 1 receptor

Rhesus HEK293 Cells
CSF1R Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.3 kDa and the accession number is XP_001107711.3.
TMPY-05043 CSF1R Protein, Rhesus, Recombinant (hFc)

colony stimulating factor 1 receptor

Rhesus HEK293 Cells
CSF1R Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.3 kDa and the accession number is XP_001107711.3.
TMPY-01833 CSF1R Protein, Mouse, Recombinant (His)

Fim-2,M-CSF-R,CD115,Csfmr,CSF-

Mouse HEK293 Cells
CSF1R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.8 kDa and the accession number is P09581.
TMPY-05429 CSF1R Protein, Human, Recombinant (hFc)

FIM2,C-FMS,FMS,MCSF Receptor,CD115,HDLS,CSF

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.2 kDa and the accession number is P07333-1.
TMPY-05264 CSF1R Protein, Human, Recombinant (mFc)

CD115,FIM2,FMS,CSF-1R,colony stimulating f...

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 81.5 kDa and the accession number is P07333-1.
TMPY-04938 CSF1R Protein, Mouse, Recombinant (His), Biotinylated

CD115,M-CSFR,colony stimulating factor 1 receptor,A...

Mouse HEK293 Cells
CSF1R Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.8 kDa and the accession number is P09581.
TMPY-04358 CSF1R Protein, Human, Recombinant (His & GST)

MCSF Receptor,FMS,colony stimulating factor 1 recep...

Human Baculovirus Insect Cells
CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76 kDa and the accession number is P07333-1.
TMPY-06384 CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated

HDLS,FMS,colony stimulating factor 1 receptor,MCSF ...

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 57.76 kDa and the accession number is P07333-1.
TMPY-06389 CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated

FMS,CD115,FIM2,MCSF Receptor,colony stimulating fac...

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 83.04 kDa and the accession number is P07333-1.
TMPY-05513 CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)

M-CSF-R,HDLS,C-FMS,CSFR,CSF-1...

Human HEK293 Cells
CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is P07333-1.
TMPY-05045 CSF1R Protein, Human, Recombinant (Domain I&II&III, His)

M-CSF-R,colony stimulating factor 1 receptor,HDLS,C...

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is P07333-1.

重组蛋白

CSF1R Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01419
Species: Cynomolgus
Expression System: HEK293 Cells
CSF1R Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01418
Species: Cynomolgus
Expression System: HEK293 Cells
CSF1R Protein, Feline, Recombinant (His & SUMO)
Cat.No: TMPH-00354
Species: Feline
Expression System: E. coli
CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
Cat.No: TMPY-01037
Species: Human
Expression System: HEK293 Cells
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00415
Species: Human
Expression System: HEK293 Cells
M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00656
Species: Cynomolgus
Expression System: HEK293 Cells
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00414
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant
Cat.No: TMPY-00881
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05436
Species: Mouse
Expression System: HEK293 Cells
CSF1R Protein, Rat, Recombinant (His)
Cat.No: TMPY-03734
Species: Rat
Expression System: HEK293 Cells
CSF1R Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03920
Species: Rat
Expression System: HEK293 Cells
CSF1R Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-05040
Species: Rhesus
Expression System: HEK293 Cells
CSF1R Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-05043
Species: Rhesus
Expression System: HEK293 Cells
CSF1R Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01833
Species: Mouse
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05429
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05264
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-04938
Species: Mouse
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04358
Species: Human
Expression System: Baculovirus Insect Cells
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06384
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06389
Species: Human
Expression System: HEK293 Cells
CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)
Cat.No: TMPY-05513
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
Cat.No: TMPY-05045
Species: Human
Expression System: HEK293 Cells
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