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Search Results for " csf-1 receptor "
Targets Recommended: c-Fms

30

抑制剂 & 化合物

1

天然产物

1740

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Cat. No. Product Name Target Signaling Pathways
T10894 CSF1R-IN-1

c-Fms Tyrosine Kinase/Adaptors
CSF1R-IN-1 是一种 CSF1R 抑制剂 (IC50:0.5 nM)。
T5586 cFMS Receptor Inhibitor II

c-Fms Tyrosine Kinase/Adaptors
cFMS Receptor Inhibitor II 是 CSF-1R 激酶抑制剂。其中 CSF-1 是细胞因子。
T13194 CSF1R-IN-2

c-Fms; c-Met/HGFR; Src Angiogenesis; Tyrosine Kinase/Adaptors
CSF1R-IN-2 是一种口服具有活力的、有效的 SRC,MET 和 c-FMS 抑制剂,它们的 IC50 值分别为 0.12 nM,0.14 nM 和 0.76 nM。
T14380 AZD7507

CSF-1R; HER; Sodium Channel Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
AZD7507 是口服具有活力的CSF-1R 抑制剂,具有抗肿瘤作用。
TQ0015 PRN1371

c-Fms; FGFR; CSF-1R Angiogenesis; Tyrosine Kinase/Adaptors
PRN1371 是一种高效的、选择性的FGFR1-4和CSF1R 抑制剂,对FGFR1,FGFR2,FGFR3,FGFR4 和 CSF1R 的IC50值分别为 0.6,1.3,4.119.3 和 8.1 nM。
T6119 Sotuletinib

BLZ945

c-Fms; CSF-1R Tyrosine Kinase/Adaptors
Sotuletinib (BLZ945) 是一种选择性的、有效的、脑渗透性的CSF-1R (c-Fms)抑制剂 (IC50:1 nM),选择性是其他受体酪氨酸激酶同系物的 1000 倍。
T10652 Vimseltinib

DCC-3014

c-Fms; CSF-1R; c-Kit Tyrosine Kinase/Adaptors
Vimseltinib (DCC-3014) 是 c-FMS(CSF-IR) 和 c-Kit 抑制剂,IC50值分别为 <0.01 μM 和 0.1-1 μM。
T2115 Pexidartinib

PLX-3397

Apoptosis; c-Fms; CSF-1R; c-Kit; FLT Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Pexidartinib (PLX-3397) 是一种 CSF-1R 和 c-Kit 的抑制剂 (IC50=20/10 nM),具有选择性、ATP 竞争性和口服活性。Pexidartinib 具有抗肿瘤活性,可以诱导细胞凋亡。
T7100 PLX5622

PLX-5622

c-Fms; CSF-1R Tyrosine Kinase/Adaptors
PLX5622 是一种选择性的、高效的、能透过血脑屏障的、口服具有活性的 CSF1R 抑制剂 (IC50= 0.016 µM;Ki= 5.9 nM),具有较好的药理学特性,可用于病程发展前和过程中,扩大的和特异性的小胶质细胞的消除。
T2659 GW2580

GW 2580,SC-203877

c-Fms Tyrosine Kinase/Adaptors
GW2580 (SC-203877) 是一种口服有效的、选择性的 c-Fms 激酶抑制剂,体外实验中在 0.06 μM 时可完全抑制人 cFMS 激酶。它是 ATP 与 cFMS 激酶结合的竞争性抑制剂,能够抑制集落刺激因子 1 信号传导。
T2624 OSI-930

OSI 930,噻尔非尼

Apoptosis; c-Fms; Raf; VEGFR; FLT; CSF-1R; Src; c-Kit Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
OSI-930 是 Kit,KDR 和 CSF-1R (c-Fms)的口服选择性抑制剂,IC50分别为 80 nM,9 nM 和 15 nM。它具有抗肿瘤活性,靶向肿瘤中的癌细胞增殖和血管生成。它还适度抑制 Flt-1,c-Raf 和 Lck,并且对 PDGFRα/β,Flt-3和 Abl 具有较弱的抑制活性。
T15199 Edicotinib

JNJ-527,JNJ-40346527

c-Fms; FLT; CSF-1R; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Edicotinib (JNJ-527) 是能够透过血脑屏障的、口服具有活性的、选择性的CSF-1R 抑制剂 (IC50:3.2 nM)。它对 KIT (IC50:20 nM) 和 FLT3 (IC50:190 nM) 的抑制作用较小。它抑制小胶质细胞的扩张,减弱小胶质细胞的增殖和神经退行性变。它可用于研究阿尔茨海默病和类风湿性关节炎。
T35570 Chiauranib

CS2164,西奥罗尼

c-Fms; VEGFR; FLT; PDGFR; c-Kit; Aurora Kinase Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
Chiauranib 是一种针对肿瘤血管生成的多靶点抑制剂,具有强大的抗癌作用。 Chiauranib 有效抑制血管生成相关激酶(VEGFR1、VEGFR2、VEGFR3、PDGFRα 和 c-Kit)、有丝分裂相关激酶 Aurora B 和慢性炎症相关激酶 CSF1R,IC50 值范围为 1-9 nM。
T4315 Ki20227

N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲

c-Fms; VEGFR; CSF-1R; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Ki20227 是一种高效的、口服具有活性的、选择性的CSF1R(c-Fms 酪氨酸激酶)抑制剂,对 CSF1R,VEGFR2,c-Kit 和PDGFRβ的IC50分别为 2 nM,12 nM,451 nM 和 217 nM。它可以阻止破骨细胞分化和溶骨性破坏。
T6930 Pazopanib Hydrochloride

GW786034,Pazopanib HCl,GW786034 HCl,盐酸帕唑帕尼,Votrient HCl,Armala

c-Fms; VEGFR; FGFR; PDGFR; c-Kit; Autophagy Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
Pazopanib Hydrochloride (Votrient HCl) 是一种多靶点抑制剂,抑制 VEGFR1、VEGFR2、VEGFR3、PDGFRβ、c-Kit、FGFR1和c-Fms 的IC50分别为10、30、47、84、74、140和146 nM。
T6289 Dovitinib

TKI258,多韦替尼,CHIR-258,度维替尼

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib (CHIR-258) 是一种口服有效的、多靶点的酪氨酸激酶 (RTK) 抑制剂,具有抗肿瘤作用。
T2514 Linifanib

利尼伐尼,ABT-869,RG3635,AL-39324

Apoptosis; c-Fms; VEGFR; FLT; CSF-1R; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors
Linifanib (AL-39324) 是一种高效口服的VEGFR 和PDGFR 家族多靶点抑制剂,具有显著的抗肿瘤活性。它对无关 RTKs、可溶性酪氨酸激酶或丝氨酸/苏氨酸激酶的活性要低得多。它是特异性 miR-10b 抑制剂,阻断miR-10b 的生物合成。
T6028 PF 477736

PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

c-Fms; VEGFR; FGFR; FLT; c-RET; Chk; CDK; Src; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
PF 477736 (PF-736,PF-00477736) 是一种特异性、有效且具有 ATP 竞争性的 Chk1 抑制剂,Ki 值为0.49 nM。它也是Chk2抑制剂,Ki 值为 47 nM。它还抑制VEGFR2、Fms、Yes、Aurora-A、FGFR3、Flt3和Ret。
T1925 PLX647

c-Fms; c-Kit Tyrosine Kinase/Adaptors
PLX647 是具有口服活性的、高效的、特异性的FMS 和KIT 双激酶抑制剂,IC50分别为 28 和 16 nM。它 (1 μM) 在 400 个激酶组中显示出对 FMS 和 KIT 有选择性,但 FLT3 和 KDR 除外 (IC50=91130 nM)。
T76776 Emactuzumab

RO 5509554,RG 7155

c-Fms; TAM Receptor Tyrosine Kinase/Adaptors
Emactuzumab(RG 7155) 是一种针对集落刺激因子-1 受体的单克隆抗体,靶向肿瘤相关巨噬细胞 (TAM)。Emactuzumab 具有抗肿瘤活性,可抑制集落刺激因子 1 受体 (CSF1R) 的激活。Emactuzumab 对 CSF-1R 具有高亲和力,Ki 值为 0.2 nM。Emactuzumab 可阻断 CSF-1R 二聚化,可用于研究如弥漫型腱鞘巨细胞瘤(dt-GCT)类的癌症。
T76908 Anumigilimab

Anumigilimab (CSL-324) 是一种人源化IgG2a 单抗,靶向人粒细胞集落刺激因子 (G-CSF) 受体。Anumigilimab 可用于炎症部位中性粒细胞数量增加的研究。
T29797 AKB-6899

AKB6899

VEGFR; HIF/HIF Prolyl-Hydroxylase; HIF Angiogenesis; Chromatin/Epigenetic; Metabolism; Tyrosine Kinase/Adaptors
AKB-6899 是脯氨酰羟化酶结构域 3 (PHD3) 的抑制剂,可增加 GM-CSF 处理的巨噬细胞产生的 VEGF 受体的可溶形式 (sVEGFR-1)。 AKB-6899 能稳定 HIF-2α,从而诱导肿瘤相关巨噬细胞产生 sVEGFR-1 并减少肿瘤生长。
T11390 GENZ-882706

RA03546849

CSF-1R Tyrosine Kinase/Adaptors
GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.
T76868 Lacnotuzumab

Lacnotuzumab (MCS110)为一种针对CSF-1的中和人源化IgG1/κ单克隆抗体,其功能是阻断CSF-1CSF-1R的激活。该化合物主要用于色素沉着绒毛结节性滑膜炎研究。
T10647 c-Fms-IN-8

CSF-1R Tyrosine Kinase/Adaptors
c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.
T10644 c-Fms-IN-10

Others Others
c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity.
T11729 JTE-952

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
JTE-952 is a oral, potent active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse
T77172 Eflapegrastim

Eflapegrastim 是一种人源化IgG4单抗 ,也是一种粒细胞集落刺激因子 (G-CSF)。Eflapegrastim 靶向G-CSF 受体 (c-Fms)。Eflapegrastim 刺激中性粒细胞祖细胞的增殖和分化,维持成熟和功能性中性粒细胞数目稳定。Eflapegrastim 还缩短中性粒细胞减少的持续时间。
T80959 Trabikibart

CSL311

Trabikibart(CSL311)为βc特异性的全人源单克隆抗体,专一性结合人βc受体的细胞因子结合位点表位,并展现高皮摩尔级别的结合亲和力。此抗体能有效抑制IL-3、GM-CSF和IL-5在嗜酸性粒细胞存活中的协同作用,显示出治疗慢性炎症性疾病的应用潜力。
T75806 Lyn peptide inhibitor TFA

Lyn peptide inhibitor TFA 是一种有效的,可以细胞渗透的抑制剂,抑制Lyn 偶联的IL-5受体相关信号通路,同时保持其他信号的完整。Lyn peptide inhibitor TFA 可以阻断 Lyn 的激活,抑制 Lyn 酪氨酸激酶与 IL-3/GM-CSF/IL-5 受体的 βc 亚基结合。Lyn peptide inhibitor TFA 可用于哮喘、过敏等嗜酸性疾病的研究。

化合物

CSF1R-IN-1
Cat.No: T10894
Synonym:
Target: c-Fms
cFMS Receptor Inhibitor II
Cat.No: T5586
Synonym:
Target: c-Fms
CSF1R-IN-2
Cat.No: T13194
Synonym:
Target: c-Fms, c-Met/HGFR, Src
AZD7507
Cat.No: T14380
Synonym:
Target: CSF-1R, HER, Sodium Channel
PRN1371
Cat.No: TQ0015
Synonym:
Target: c-Fms, FGFR, CSF-1R
Sotuletinib
Cat.No: T6119
Synonym: BLZ945
Target: c-Fms, CSF-1R
Vimseltinib
Cat.No: T10652
Synonym: DCC-3014
Target: c-Fms, CSF-1R, c-Kit
Pexidartinib
Cat.No: T2115
Synonym: PLX-3397
Target: Apoptosis, c-Fms, CSF-1R, c-Kit, FLT
PLX5622
Cat.No: T7100
Synonym: PLX-5622
Target: c-Fms, CSF-1R
GW2580
Cat.No: T2659
Synonym: GW 2580,SC-203877
Target: c-Fms
OSI-930
Cat.No: T2624
Synonym: OSI 930,噻尔非尼
Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit
Edicotinib
Cat.No: T15199
Synonym: JNJ-527,JNJ-40346527
Target: c-Fms, FLT, CSF-1R, c-Kit
Chiauranib
Cat.No: T35570
Synonym: CS2164,西奥罗尼
Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase
Ki20227
Cat.No: T4315
Synonym: N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲
Target: c-Fms, VEGFR, CSF-1R, PDGFR, c-Kit
Pazopanib Hydrochloride
Cat.No: T6930
Synonym: GW786034,Pazopanib HCl,GW786034 HCl,盐酸帕唑帕尼,Votrient HCl,Armala
Target: c-Fms, VEGFR, FGFR, PDGFR, c-Kit, Autophagy
Dovitinib
Cat.No: T6289
Synonym: TKI258,多韦替尼,CHIR-258,度维替尼
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Linifanib
Cat.No: T2514
Synonym: 利尼伐尼,ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
PF 477736
Cat.No: T6028
Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736
Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase
PLX647
Cat.No: T1925
Synonym:
Target: c-Fms, c-Kit
Emactuzumab
Cat.No: T76776
Synonym: RO 5509554,RG 7155
Target: c-Fms, TAM Receptor
Anumigilimab
Cat.No: T76908
Synonym:
Target:
AKB-6899
Cat.No: T29797
Synonym: AKB6899
Target: VEGFR, HIF/HIF Prolyl-Hydroxylase, HIF
GENZ-882706
Cat.No: T11390
Synonym: RA03546849
Target: CSF-1R
Lacnotuzumab
Cat.No: T76868
Synonym:
Target:
c-Fms-IN-8
Cat.No: T10647
Synonym:
Target: CSF-1R
c-Fms-IN-10
Cat.No: T10644
Synonym:
Target: Others
JTE-952
Cat.No: T11729
Synonym:
Target: Histamine Receptor
Eflapegrastim
Cat.No: T77172
Synonym:
Target:
Trabikibart
Cat.No: T80959
Synonym: CSL311
Target:
Lyn peptide inhibitor TFA
Cat.No: T75806
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4710 3-Methoxytyramine hydrochloride

3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐

Others; Endogenous Metabolite; Drug Metabolite Metabolism; Others
3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) 是多巴胺的无活性代谢物,能够活化痕量胺相关受体1

天然产物

3-Methoxytyramine hydrochloride
Cat.No: T4710
Synonym: 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐
Target: Others, Endogenous Metabolite, Drug Metabolite
Cat. No. Product Name Species Expression System
TMPY-01037 CSF1R Protein (Met1-Glu512), Human, Recombinant (His)

CSF-1R,CD115,HDLS,FIM2,M...

Human HEK293 Cells
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is P07333-1.
TMPJ-01419 CSF1R Protein, Cynomolgus, Recombinant (His)

CSF-1-R,CSF-1 recept...

Cynomolgus HEK293 Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ...
TMPJ-01418 CSF1R Protein, Cynomolgus, Recombinant (hFc)

M-CSF-R,CSF1R,CSF-1<...

Cynomolgus HEK293 Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ...
TMPH-00354 CSF1R Protein, Feline, Recombinant (His & SUMO)

FMS,M-CSF-R,CSF-1-R,CSF<...

Feline E. coli
CSF1R Protein, Feline, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 70.8 kDa and the accession number is P13369.
TMPY-06384 CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated

HDLS,FMS,colony stimulating factor 1 receptor

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 57.76 kDa and the accession number is P07333-1.
TMPY-05429 CSF1R Protein, Human, Recombinant (hFc)

FIM2,C-FMS,FMS,MCSF Receptor,CD1<...

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.2 kDa and the accession number is P07333-1.
TMPY-00881 CSF1R Protein, Human, Recombinant

FIM2,C-FMS,CD115,CSFR,MCSF

Human HEK293 Cells
CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.
TMPY-05045 CSF1R Protein, Human, Recombinant (Domain I&II&III, His)

M-CSF-R,colony stimulating factor 1 re...

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is P07333-1.
TMPY-05513 CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)

M-CSF-R,HDLS,C-FMS,CSFR,CSF-1...

Human HEK293 Cells
CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is P07333-1.
TMPY-06389 CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated

FMS,CD115,FIM2,MCSF Receptor<...

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 83.04 kDa and the accession number is P07333-1.
TMPY-05264 CSF1R Protein, Human, Recombinant (mFc)

CD115,FIM2,FMS,CSF-1R,co...

Human HEK293 Cells
CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 81.5 kDa and the accession number is P07333-1.
TMPY-04358 CSF1R Protein, Human, Recombinant (His & GST)

MCSF Receptor,FMS,colony stimulating facto...

Human Baculovirus Insect Cells
CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76 kDa and the accession number is P07333-1.
TMPY-05436 CSF1R Protein, Mouse, Recombinant (hFc)

AI323359,Csfmr,Fim-2,Fms,colony stimulating factor ...

Mouse HEK293 Cells
CSF1R Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.9 kDa and the accession number is P09581.
TMPY-04938 CSF1R Protein, Mouse, Recombinant (His), Biotinylated

CD115,M-CSFR,colony stimulating f...

Mouse HEK293 Cells
CSF1R Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.8 kDa and the accession number is P09581.
TMPY-01833 CSF1R Protein, Mouse, Recombinant (His)

Fim-2,M-CSF-R,CD115,Csfm...

Mouse HEK293 Cells
CSF1R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.8 kDa and the accession number is P09581.
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Vascular endothelial growth factor receptor 1

Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPJ-00402 CD117 Protein, Human, Recombinant (hFc)

KIT,CD117,v-kit Hardy-Zuckerman 4 feline s...

Human HEK293 Cells
C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1/PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing sti...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-01894 SIGIRR Protein, Human, Recombinant (His)

TIR8,single immunoglobulin and toll-interleukin 1 <...

Human HEK293 Cells
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His)

FLK2,FLK-2,CD135,STK1,fms-related tyrosine...

Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-03290 HGF Protein, Mouse, Recombinant

hepatocyte growth factor (hepapoietin A,NK1,scatter...

Mouse HEK293 Cells
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and...

Human HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-01147 R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

RSPO,CRISTIN3,R-spondin 1

Human HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular c...

Human HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-01949 CD19 Protein, Human, Recombinant (His)

CD19 molecule,B4,CVID3

Human HEK293 Cells
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-04165 FGFR3 Protein, Human, Recombinant (His)

JTK4,CEK2,fibroblast growth factor receptor 3,HSFGF...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S)

Ighg1,IgG1 Fc

Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His)

ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...

Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 4

Human,Rhesus HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His)

thymic stromal lymphopoietin

Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor receptor...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-00853 IL-1RA Protein, Human, Recombinant

DIRA,IL1RA,interleukin 1 receptor...

Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC11987...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G1<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His)

ActRIIB,activin A receptor, type IIB,493051

Mouse HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-01851 CD73 Protein, Human, Recombinant (His)

eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His)

BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3

Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-05208 PD-L1 Protein, Human, Recombinant

CD274 molecule,PDCD1L1,PD-L1,PDL<...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-00978 Progranulin Protein, Human, Recombinant (His)

PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...

Human HEK293 Cells
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-01258 IL-13RA1 Protein, Human, Recombinant (His)

NR4,interleukin 13 receptor, alpha 1

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-03531 PSGL-1/CD162 Protein, Human, Recombinant (His)

selectin P ligand,PSGL-1,PSGL1,CD1

Human HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
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重组蛋白

CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
Cat.No: TMPY-01037
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01419
Species: Cynomolgus
Expression System: HEK293 Cells
CSF1R Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01418
Species: Cynomolgus
Expression System: HEK293 Cells
CSF1R Protein, Feline, Recombinant (His & SUMO)
Cat.No: TMPH-00354
Species: Feline
Expression System: E. coli
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06384
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05429
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant
Cat.No: TMPY-00881
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
Cat.No: TMPY-05045
Species: Human
Expression System: HEK293 Cells
CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)
Cat.No: TMPY-05513
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06389
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05264
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04358
Species: Human
Expression System: Baculovirus Insect Cells
CSF1R Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05436
Species: Mouse
Expression System: HEK293 Cells
CSF1R Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-04938
Species: Mouse
Expression System: HEK293 Cells
CSF1R Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01833
Species: Mouse
Expression System: HEK293 Cells
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00412
Species: Human
Expression System: HEK293 Cells
CD117 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00402
Species: Human
Expression System: HEK293 Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
SIGIRR Protein, Human, Recombinant (His)
Cat.No: TMPY-01894
Species: Human
Expression System: HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His)
Cat.No: TMPY-01247
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
HGF Protein, Mouse, Recombinant
Cat.No: TMPY-03290
Species: Mouse
Expression System: HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01147
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (His)
Cat.No: TMPY-01949
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04165
Species: Human
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
Cat.No: TMPY-00820
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04348
Species: Human
Expression System: HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His)
Cat.No: TMPY-02813
Species: Human,Rhesus
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
Cat.No: TMPY-05220
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
IL-1RA Protein, Human, Recombinant
Cat.No: TMPY-00853
Species: Human
Expression System: E. coli
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01281
Species: Mouse
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (His)
Cat.No: TMPY-01851
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03967
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant
Cat.No: TMPY-05208
Species: Human
Expression System: HEK293 Cells
Progranulin Protein, Human, Recombinant (His)
Cat.No: TMPY-00978
Species: Human
Expression System: HEK293 Cells
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
IL-13RA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01258
Species: Human
Expression System: HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His)
Cat.No: TMPY-03531
Species: Human
Expression System: HEK293 Cells
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