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Search Results for " cry1 "

Targets Recommended: Others

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9608	KL201	Others	Others
	KL201 是一种昼夜节律调制器，是 CRY1选择性的稳定剂，对 CRY2 没有稳定作用。KL201 延长了细胞和组织中的昼夜节律周期。
T32401	KL044 KL 044,KL-044	Others	Others
	KL044 是一种隐花色素 1（CRY1）激活剂，可延长昼夜节律并抑制 PER2 的活性。 KL044 通过抑制cAMP/PKA/CREB 通路来抑制黑色素生成。
T22891	KL001 KL 001,KL-001	Others	Others
	KL001 是一流的隐花色素蛋白 (CRY)稳定剂，可与 CRY1 和 CRY2 特异性相互作用。其中CRY 是一种对蓝光敏感的黄素蛋白，参与调节动植物的昼夜节律。KL001能够防止泛素依赖性 CRY 降解，从而延长了昼夜节律周期，具有控制空腹激素诱导的糖异生的潜力。
T74743	M47	Others	Others
	M47 是一种小分子，可选择性地破坏隐花色素 1 (CRY1) 的稳定性并增加细胞核中 CRY1 的降解。M47 增强Ras 转化的 P53 缺陷小鼠皮肤成纤维细胞系的细胞凋亡，并延长 p53 基因敲除小鼠的寿命。M47 可用于癌症研究。
T38433	KS15	Others	Others
	KS15 is a chemical compound that acts as an inhibitor on the interactions between cryptochromes, specifically CRY1 and CRY2, and the CLOCK: BMAL1 heterodimer. This compound, with an EC50 value of 4.9 μM, hinders the feedback actions of CRYs on E-box-dependent transcription. The CLOCK: BMAL1 heterodimer is a vital transcriptional regulator for the mammalian circadian clock. In addition, KS15 exhibits significant anti-proliferative activity.

化合物

Synonym: KL 044,KL-044

Target: Others

KL001

Cat.No: T22891

Synonym: KL 001,KL-001

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01159	CRY1 Protein, Human, Recombinant (His & Myc) PHLL1,CRY1,Cryptochrome-...	Human	E. coli
	CRY1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q16526.
TMPH-00180	Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His & SUMO) Pesticidal crystal protein Cry1Ab...	Bacillus thuringiensis subsp. kurstaki	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.3 kDa and the accession number is P0A370.
TMPH-00179	Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His) bt2,cryIA(b),130 kDa crystal prot...	Bacillus thuringiensis subsp. kurstaki	P. pastoris (Yeast)
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 17.3 kDa and the accession number is P0A370.
TMPH-00183	Cry1Ac Protein, Bacillus thuringiensis subsp., Recombinant (GST) cryIA(c),Insecticidal delta-endotoxin CryI...	Bacillus thuringiensis subsp. kurstaki	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ac Protein, Bacillus thuringiensis subsp., Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 50.8 kDa and the accession number is P05068.
TMPH-00181	Cry1Ia Protein, Bacillus thuringiensis subsp., Recombinant (His & KSI) cryV1,cry1Ia,cry	Bacillus thuringiensis subsp. Kurstaki	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of certain coleopteran and lepidopteran species. Active on Plutella xylostella and Bombyx mori. Cry1Ia Protein, Bacillus thuringiensis subsp., Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 24.9 kDa and the accession number is Q45752.
TMPH-00184	Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His) cryIF(b),Crystaline entomocidal protoxin,I...	Bacillus thuringiensis subsp. morrisoni	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects. Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.3 kDa and the accession number is O66377.
TMPH-00177	Cry1Bb Protein, Bacillus thuringiensis, Recombinant (His & Myc) cry1Bb,Crystaline entomocidal pro...	Bacillus thuringiensis	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Bb Protein, Bacillus thuringiensis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.1 kDa and the accession number is Q45739.