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Search Results for " crom "

Targets Recommended: Potassium Channel

19

抑制剂 & 化合物

9

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T21478	Cromakalim BRL34915,(±)-Cromakalim,BRL 34915,BRL-34915	Potassium Channel	Membrane transporter/Ion channel
	Cromakalim (BRL 34915) 是一种 ATP 依赖性 K（+）通道开启剂，是一种平滑肌松弛剂。Cromakalim 具有抗癫痫和抗惊厥活性，可用于研究哮喘和与血管扩张相关的疾病。
T16280	Nedocromil FPL 59002,尼多克罗	Leukotriene Receptor; Prostaglandin Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Nedocromil (FPL 59002) 对多种介质的作用或形成有抑制作用，包括组胺，前列腺素 D2和白三烯 C4。
TQ0150	Levcromakalim (-)-Cromakalim,左色满卡林,BRL 38227	Potassium Channel	Membrane transporter/Ion channel
	Levcromakalim (BRL 38227) 是一种 ATP 敏感性的 K+通道 (KATP) 激活剂。
T8239	Cromoglicic acid	Others	Others
	Cromoglicic acid 可防止肥大细胞释放炎性化学物质，例如组胺。
T1260	Cromolyn sodium Disodium Cromoglycate,FPL 670 (Cromolyn) Disodium,FPL-670,色甘酸钠,Sodium cromoglycate	Others; Potassium Channel; GSK-3; Calcium Channel	Membrane transporter/Ion channel; Metabolism; Others; PI3K/Akt/mTOR signaling; Stem Cells
	Cromolyn sodium (FPL-670) 是一种GSK-3β抑制剂，IC50为 2.0 µM，有抗过敏作用。
T38013	Sonlicromanol hydrochloride KH 176 hydrochloride	ROS	Immunology/Inflammation
	Sonlicromanol hydrochloride (KH176 hydrochloride) 是可透过血脑屏障的 ROS-redox 调节剂，具有潜在的抗癌活性，可改善 iPSC 衍生神经元中与 m.3243A>G 异质相关的神经元网络功能障碍和转录组变化，可用于治疗线粒体疾病。
T15344	Minocromil 米诺罗米,FPL59360	Others	Others
	Minocromil is a new agent of Anti-asthmatic.
T69059	Cromoglicate sodium hydrate	Others	Others
	Cromoglicic acid , cromolyn (USAN), cromoglycate (former BAN), or cromoglicate, is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma. Cro...
T28980	Tisocromide	Others	Others
	Tisocromide is an antihypoxic agent.
T75084	Foslevcromakalim	Others	Others
	Foslevcromakalim (QLS-101 ) 是一种ATP 敏感的钾通道开启剂。Foslevcromakalim 是用于降眼压作用的前体。
T68761	Cloricromen hydrochloride Cloricromene hydrochloride,Cloricromen hydrochloride	Others	Others
	Cloricromen hydrochloride，一种血小板聚集抑制剂，能够抑制人体及实验性血栓形成中的血小板聚集。
T23899	Cloricromen O=C(OCC)COC1=CC=C(C(O2)=C1Cl)C(C)=C(CCN(CC)CC)C2=O	Others	Others
	Cloricromen is an inhibitor of platelet aggregation.
T38326	Cromolyn (sodium salt hydrate)	Others	Others
	Cromolyn is a chromone complex that acts as a mast cell stabilizer, preventing the release of histamine. Its mechanism of action is thought to involve an interference with the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions.
T19472	Nedocromil sodium Nedocromil disodium salt,FPL 59002KP	Others	Others
	Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.
T29951	Ambicromil	Others	Others
	Ambicromil is used for allergic rhinitis.
T25955	Picromycin Antibiotic B 62169A,Amaromycin,Albomycetin,Pikromycin	Others	Others
	Picromycin is a 14-membered macrolide antibiotic and Prolyl endopeptidase (PREP) inhibitor. Pikromycin shows activity against gram-positive bacteria including mycobacteria.
T125886	Acetyldihydromicromelin B	Others	Others
	Acetyldihydromicromelin B 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125886。
T124114	Microminutin	Others	Others
	Microminutin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124114，CAS号为 84041-46-3。
T32392	Sonlicromanol KH-176,KH 176,KH176	Others	Others
	KH-176 is an effective intracellular REDOX regulator that targets reactive oxygen species, which are important in the pathogenesis of mitochondrial oxidative phosphorylation disorders and may be used to treat mitochondrial diseases.

化合物

Cat.No: T21478

Synonym: BRL34915,(±)-Cromakalim,BRL 34915,BRL-34915

Target: Potassium Channel

Cat.No: T16280

Synonym: FPL 59002,尼多克罗

Target: Leukotriene Receptor, Prostaglandin Receptor, Histamine Receptor

Cat.No: TQ0150

Synonym: (-)-Cromakalim,左色满卡林,BRL 38227

Target: Potassium Channel

Cromoglicic acid

Cat.No: T8239

Target: Others

Cromolyn sodium

Cat.No: T1260

Synonym: Disodium Cromoglycate,FPL 670 (Cromolyn) Disodium,FPL-670,色甘酸钠,Sodium cromoglycate

Target: Others, Potassium Channel, GSK-3, Calcium Channel

Sonlicromanol hydrochloride

Cat.No: T38013

Synonym: KH 176 hydrochloride

Target: ROS

Cat.No: T15344

Synonym: 米诺罗米,FPL59360

Target: Others

Cromoglicate sodium hydrate

Cat.No: T69059

Target: Others

Cat.No: T28980

Target: Others

Foslevcromakalim

Cat.No: T75084

Target: Others

Cloricromen hydrochloride

Cat.No: T68761

Synonym: Cloricromene hydrochloride,Cloricromen hydrochloride

Target: Others

Cat.No: T23899

Synonym: O=C(OCC)COC1=CC=C(C(O2)=C1Cl)C(C)=C(CCN(CC)CC)C2=O

Target: Others

Cromolyn (sodium salt hydrate)

Cat.No: T38326

Target: Others

Nedocromil sodium

Cat.No: T19472

Synonym: Nedocromil disodium salt,FPL 59002KP

Target: Others

Cat.No: T29951

Target: Others

Cat.No: T25955

Synonym: Antibiotic B 62169A,Amaromycin,Albomycetin,Pikromycin

Target: Others

Acetyldihydromicromelin B

Cat.No: T125886

Target: Others

Cat.No: T124114

Target: Others

Cat.No: T32392

Synonym: KH-176,KH 176,KH176

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN7122	Micromarin F E-Methylarnottinin,5'-hydroxylosthole	Others	Others
	Micromarin F (E-Methylarnottinin) 是从 Micromelum minutum Wight et Arn 的茎中提取的香豆素衍生物。
TN4233	Hydramicromelin D	Others	Others
	Hydramicromelin D is a natural product from Micromelum integerrimum.
TN3853	Dihydromicromelin B	Others	Others
	Dihydromicromelin B is a natural product from Micromelum sp.
TN5885	Hydramicromelin B
	Hydramicromelin B is a natural product from Micromelum integerrimum.
TN3342	Acetyldihydromicromelin A	Others	Others
	Acetyldihydromicromelin A是一种天然产物，属于芸香科小芸木属，其产品编号为 TN3342，CAS号为 94285-22-0。Acetyldihydromicromelin A可用作对照参考。
TN4564	Micromelin	Others	Others
	Micromelin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100.
TN4980	Secodihydro-hydramicromelin B	Others	Others
	Secodihydro-hydramicromelin B 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4980，CAS号为 1212148-58-7。
T81794	Micromonosporamide A
	Micromonosporamide A exhibits glutamine-dependent antiproliferative activity. Micromonosporamide A体现了以谷氨酰胺为依赖的抗增殖活性。
T31152	Cynanester A
	Cynanester A comes from crom Cynanchum chinense R. Br.

天然产物

Cat.No: TN7122

Synonym: E-Methylarnottinin,5'-hydroxylosthole

Target: Others

Hydramicromelin D

Cat.No: TN4233

Target: Others

Dihydromicromelin B

Cat.No: TN3853

Target: Others

Hydramicromelin B

Cat.No: TN5885

Acetyldihydromicromelin A

Cat.No: TN3342

Target: Others

Cat.No: TN4564

Target: Others

Secodihydro-hydramicromelin B

Cat.No: TN4980

Target: Others

Micromonosporamide A

Cat.No: T81794

Cat.No: T31152

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00550	CD55/DAF Protein, Cynomolgus, Recombinant (His) TC,DAF-GPI,CR,CROM,Daf1,CD55,Cd55a,DAF	Cynomolgus	HEK293 Cells
	Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection.
TMPY-00713	CD55/DAF Protein, Human, Recombinant (hFc) CR,CD55 molecule, decay accelerating factor for complement (...	Human	HEK293 Cells
	CD55/DAF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.7 kDa and the accession number is P08174-1.
TMPY-01292	CD55/DAF Protein, Human, Recombinant (His) CD55 molecule, decay accelerating factor for complement (	Human	HEK293 Cells
	CD55/DAF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P08174-1.

重组蛋白

CD55/DAF Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00550

Species: Cynomolgus

Expression System: HEK293 Cells

CD55/DAF Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00713

Species: Human

Expression System: HEK293 Cells

CD55/DAF Protein, Human, Recombinant (His)

Cat.No: TMPY-01292

Species: Human

Expression System: HEK293 Cells

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