134
40
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Cat. No. | Product Name | ||
---|---|---|---|
L6001 | Mini真菌代谢天然产物筛选库 | Inquiry | |
LF9200 | LC 共价筛选化合物库 | 34700 compounds | |
L2192 | 抗胰腺癌化合物库 | 2238 compounds | |
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L9500 | 表型筛选靶点鉴定库 | 1796 compounds | |
1796 种靶点明确的已知活性化合物,适合表型筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T60050 |
ANT3310
|
Antibacterial | Microbiology/Virology |
ANT3310 是一种广谱共价丝氨酸 β-内酰胺酶抑制剂,对 AmpC、CTX-M-15、TEM-1、OXA-48、OXA-23 和 KPC-2 的 IC50 范围为 1 nM 至 175 nM。 ANT3310 可用于细菌感染研究。 | |||
T0517 |
Pancreatin
Pancreatic enzymes,pancrelipase,胰酶 |
Others | Others |
Pancreatin (pancrelipase) 是一种含有胰腺消化酶的猪胰腺提取物。 | |||
TP1044L |
Pancreatic Polypeptide, rat acetate
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Pancreatic Polypeptide, rat acetate 是 NPY 受体的激动剂,对 NPYR4 具有高亲和力。 | |||
T11358 |
gamma-secretase modulator 1
N-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]-4-phenyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine |
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
gamma-secretase modulator 1 是一种 γ 分泌酶的调节剂,可用于治疗阿尔茨海默病的研究。 | |||
T62263 |
γ-Secretase modulator 13
|
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
γ-Secretase modulator 13 是一种 γ-分泌酶调节剂 (GSMs),可以抑制淀粉样蛋白 β 肽Aβ42 的产生,可以用于研究阿尔茨海默病和肿瘤。 | |||
TP1597L |
Secretoneurin, rat acetate
Secretoneurin, rat acetate(149146-12-3 Free base) |
Others | Others |
Secretoneurin, rat acetate 是一种 33 个氨基酸的多肽,由分泌粒蛋白 II (SgII) 的蛋白水解加工产生。它在体内和体外诱导大鼠纹状体中的多巴胺释放,它对单核细胞和嗜酸性粒细胞有很强的趋化作用,但对粒细胞没有。 | |||
T3521 |
γ-Secretase-IN-1
Compound E |
Beta Amyloid; Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
γ-Secretase-IN-1 是一种高效的 γ-secretase 抑制剂,对T-47D 细胞显示部分抗增殖活性且抑制 β-amyloid(40),β-amyloid(42),和Notch γ-分泌酶裂解。 | |||
TP1039 |
Secretin (33-59), rat
大鼠SECRETIN肽,Secretin (rat) |
Glucagon Receptor | GPCR/G Protein |
Secretin (33-59), rat (Secretin (rat)) 是由 27 个氨基酸组成的多肽。Secretin (33-59), rat 可作用于分泌素受体,能够增强胰腺的碳酸盐、酶和钾离子的分泌。 | |||
T9441 |
2-Amino-p-cresol
|
Others | Others |
2-Amino-p-cresol 是合成多种化合物的中间体,包括药物、染料等;还被用作合成各种聚合物的试剂和酶的抑制剂。 | |||
T19498 |
p-Cresyl sulfate potassium
p-Tolyl sulfate potassium salt,p-Cresol sulfate potassium,p-Methylphenyl potassium sulfate,对甲基硫酸钾,Potassium p-tolyl sulfate |
Endogenous Metabolite | Metabolism |
p-Cresyl sulfate potassium (p-Tolyl sulfate potassium salt) 是一种尿毒症毒素,能够与原型蛋白质结合。 | |||
T2677 |
Crenolanib
ARO 002,CP-868596 |
FLT; PDGFR; Autophagy | Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors |
Crenolanib (ARO 002) 是一种口服生物可利用的 III 型酪氨酸激酶抑制剂,抑制 FLT3和 PDGFRα/β的 IC50分别为 4、11和 3.2 nM。 | |||
T3633 |
Crenigacestat
LY3039478 |
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
Crenigacestat (LY3039478) 是一种口服具有活性的Notch 和γ-secretase 的抑制剂,其在多种肿瘤细胞中的IC50为 ∼1nM。 | |||
T3942 |
Cremophor EL
|
Others | Others |
T4557 |
Amylmetacresol
戊甲酚,5-Methyl-2-Pentylphenol |
Others; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
Amylmetacresol (5-Methyl-2-Pentylphenol) 是一种有潜力研究咽喉痛相关疾病的抗病毒化合物。 | |||
TP1137L |
Pancreatic Polypeptide (human) acetate
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Pancreatic Polypeptide (human) acetate 是一种 C 末端酰胺化的 36 个氨基酸肽,可作为神经肽 Y (NPY) Y4/Y5 受体激动剂。 | |||
T27083 |
Crebinostat
|
Epigenetic Reader Domain; Histone Acetyltransferase; HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Crebinostat 是一种有效的组蛋白去乙酰化酶 (HDAC) 抑制剂,对 HDAC1、HDAC2、HDAC3 和 HDAC6 有抑制作用, IC50 分别为 0.7 nM、1.0 nM、2.0 nM 和 9.3 nM。Crebinostat 可增加在体外神经元的突触蛋白 1 斑点沿树突 (synapsin-1 punctae along dendrites) 的密度。Crebinostat 可调节染色质介导的神经可塑性,增强小鼠的记忆。Crebinostat 可诱导组蛋白 H3 和组蛋白 H4 乙酰化,并增强 cAMP 反应元件结合蛋白 (CREB) 靶基因 Egr1 的表达。 | |||
T40495 |
Elastase from porcine pancreas
弹性蛋白酶,EC 3.2.1.35 |
Others | Others |
Elastase from porcine pancreas 由 240 个氨基酸残基组成,是一种丝氨酸蛋白酶,可以水解蛋白质和多肽。它可诱发仓鼠气肿。 | |||
T9713 |
δ-secretase inhibitor 11
|
Beta Amyloid; Caspase | Apoptosis; Neuroscience; Proteases/Proteasome |
δ-secretase inhibitor 11是一种分泌酶抑制剂,可用作 阿尔茨海默病(AD) 治疗转化开发的先导化合物。 | |||
TP1876L |
CREBtide acetate(149155-45-3 free base)
|
PKA | Tyrosine Kinase/Adaptors |
CREBtide acetate(149155-45-3 free base) 是 PKA (Km=3.9 µM) 的合成底物,它基于 d-CREB(cAMP 反应元件结合蛋白)中的磷酸化序列。 | |||
T9241 |
o-Cresolphthalein Complexone
|
Others | Others |
o-Cresolphthalein Complexone 是一种金属络合指示剂和酸碱指示剂。 | |||
TP1044 |
Pancreatic Polypeptide, rat
Rat pancreatic polypeptide |
||
Pancreatic Polypeptide, rat is an agonist of NPY receptor, with high affinity at NPYR4. Pancreatic polypeptide (PP) is a 36-amino acid, C-terminally amidated peptide, and is a member of the PP-fold peptide family. It is produced and secreted by the PP cel | |||
T76437 |
Hypocretin (70-98), human
|
||
Hypocretin (70-98), human 是一种多肽,能够与食欲素受体OX1R 结合,促进凋亡 (apoptosis)。 | |||
T82670 |
Crefmirlimab
89Zr-Df-IAB22M2C |
||
Crefmirlimab(89Zr-Df-IAB22M2C)为针对CD8抗原的人源化CD8探针,适用于多种癌症诊断。 | |||
T81554 |
Pancreastatin (37-52), human
|
||
Pancreastatin (37-52), human, 是一段具有生物活性的 CgA 衍生肽(CgA 残基 250-301),它能够抑制胰岛β细胞释放胰岛素。 | |||
T78659 |
Crexavibart
BMS-986413,C-144-LS |
SARS-CoV | Microbiology/Virology |
Crexavibart (BMS-986413; C-144-LS)是一种IgG1λ2抗体,专门针对SARS-CoV-2刺突(S)糖蛋白的受体结合域。 | |||
T81553 |
Pancreastatin (swine)
|
||
Pancreastatin (swine)为含49个氨基酸残基的多肽,强效抑制葡萄糖刺激之胰岛素释放,可自猪胰腺分离鉴定。 | |||
T18935 |
Cresyl Violet acetate
|
Others | Others |
Cresyl Violet acetate is a red fluorescent stain used to stain neurons. | |||
T10064 |
LH secretion antagonist 1
|
Others | Others |
LH secretion antagonist 1 is an antagonist of luteinizing hormone secretion with analgesic activity. | |||
T11358L |
gamma-secretase modulator 1 hydrochloride
gamma-secretase modulator 1 hydrochloride (1172637-87-4 free base) |
Others | Others |
gamma-secretase inhibitior-1 是γ-secretase 调节剂,gamma-secretase inhibitior-1可用于阿尔茨海默病。 | |||
T78250 |
Selicrelumab
|
||
Selicrelumab是一种针对CD40的抗体激动剂,能够诱导肿瘤微环境的改变,适用于胰腺癌及肿瘤新辅助治疗的研究。 | |||
T62455 |
β-Secretase Inhibitor III
|
Others | Others |
β-Secretase Inhibitor III 是一种高度选择性的 BACE1 抑制剂,其 Ki 值为 0.13 nM。 | |||
T40631 |
4-Hydroxytryptamine creatinine sulfate
|
Others | Others |
4-Hydroxytryptamine creatinine sulfate, a derivative of tryptamine, acts as an agonist for neurotransmitters. | |||
T65428 |
Secretin,porcine
|
Others | Others |
Secretin,porcine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65428。 | |||
T29478 |
6-tert-Butyl-4-chloro-m-cresol
|
Others | Others |
6-tert-Butyl-4-chloro-m-cresol is a bioactive chemical. | |||
T64685 |
Secretin xAcetate
|
Others | Others |
Secretin xAcetate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64685。 | |||
T29427 |
4,6-Diisopropyl-m-cresol
|
Others | Others |
4,6-Diisopropyl-m-cresol is a bioactive chemical. | |||
T36421 |
Immuno-Oncology Screening Library
|
Others | Others |
The Immuno-Oncology Screening Library consists of 2 plates and contains more than 90 cancer and immunology-associated compounds in a 96-well Matrix tube rack format as 10 mM stock solutions in DMSO. This library includes a variety of immuno-oncology target modulators, including but not limited to, adenosine, CCR, CXCR, and TLR agonists and antagonists, BTK, PI3K, VEGFR, and BRAF inhibitors, PD-1/PDL-1 interaction inhibitors, and HDAC inhibitors. Please review the product insert for a full list ... | |||
T40315 |
γ-Secretase modulator 10
|
Others | Others |
γ-Secretase modulator 10 is a novel γ-secretase modulator. | |||
T125448 |
Creatinine Phosphate Disodium Salt
|
Others | Others |
Creatinine Phosphate Disodium Salt 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125448。 | |||
T33232 |
m-Cresol, 6-(methylthio)-
|
Others | Others |
m-Cresol, 6-(methylthio)- is a bioactive chemical. | |||
T29472 |
6-Hexyl-m-cresol
|
Others | Others |
6-Hexyl-m-cresol is a bioactive chemical. | |||
T27082 |
CREBBP-IN-9
CREBBPIN9,CREBBP IN 9 |
Others | Others |
CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein. | |||
T33229 |
m-Cresol thiocyanate
|
Others | Others |
m-Cresol thiocyanate is a bioactive chemical. | |||
T23822 |
Brocresine
|
Others | Others |
Brocresine is an aromatic L-amino acid decarboxylase inhibitor. It has both a peripheral and central action. | |||
T75913 |
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA
|
||
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide 为高效且选择性的神经肽 YY5 受体激动剂,其与 hY5 受体的结合 IC50 值为 0.24 nM,已知可促进饮食摄入。 | |||
T11362 |
gamma-Secretase Modulators
γ-Secretase Modulators,Amyloid-β production inhibitor |
Others | Others |
gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β. Specifically, it acts as a gamma-Secretase Modulators with an IC50 value. | |||
T11359 | gamma-secretase modulator 2 | Others | Others |
gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's disease .γ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer's disease. | |||
T76538 |
Pancreatic polypeptide
|
||
Pancreatic polypeptide 是由胰腺内分泌的 PP 细胞所分泌的多肽,具有调节胰腺分泌功能、影响肝糖原储存及胃肠分泌的作用。 | |||
T81556 |
Pancreastatin
|
||
Pancreastatin(胰酶素,PST),这种肽类化合物具有生物活性,能够增加肝脏的葡萄糖输出,进而导致糖尿病。 | |||
T18936 |
Cresyl Violet perchlorate
Oxazine 9 perchlorate |
Others | Others |
Cresyl Violet perchlorate is a red fluorescent stain used to stain neurons. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3262 |
Phosphocreatine disodium
Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt,磷酸肌酸钠 |
Others; Endogenous Metabolite | Metabolism; Others |
Phosphocreatine disodium (Phosphocreatine disodium salt) 是一种磷酸化的肌酸分子,在肌肉、骨骼和大脑中作为一种可快速动员的高能磷酸盐储备。 | |||
T2S2215 |
Crebanine
|
Apoptosis; Others; Akt | Apoptosis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling |
Crebanine 是来自于韦诺萨千金藤的一种生物碱,通过抑制 MAPKs 和 Akt 信号通路表现出抗炎活性,还具有抗心律失常的作用。它可诱导人类癌细胞的 G1阻滞和凋亡。 | |||
T4860 |
5-Hydroxytryptamine creatinine sulfate monohydrate
Serotonin creatinine sulfate monohydrate,5-Hydroxytryptamine creatinine sulfate complex,5-五羟色胺肌酸酐 |
Others; Endogenous Metabolite | Metabolism; Others |
5-Hydroxytryptamine creatinine sulfate monohydrate (Serotonin creatinine sulfate monohydrate) 是内源性代谢产物的一种。 | |||
T5780 |
HYPOCRELLIN B
|
Apoptosis; Parasite; Antifungal | Apoptosis; Microbiology/Virology |
Hypocrellin B 是从真菌Hypocrella bambusae 和Shiraia bambusicola 中分离得到的一种感光颜料,可用于癌症光动力研究。它是一个凋亡诱导剂,还拥有抗菌和抗利什曼活性。 | |||
T0496 |
Creatinine
肌酸酐,NSC13123 |
Endogenous Metabolite | Metabolism |
Creatinine (NSC-13123) 由肌肉中磷酸肌酸分解产生。 | |||
T5771 |
Hypocrellin A
|
Antibacterial; PKC; Parasite | Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology |
Hypocrellin A 是一种天然的PKC 抑制剂,具有光诱导的抗肿瘤、抗真菌和抗病毒活性,还对 MHC 限制性抗原呈递发挥免疫调节作用。 | |||
T4888 |
Phosphocreatine disodium hydrate
磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Phosphocreatine disodium hydrate 是内源性代谢产物的一种。 | |||
T4739 |
Sodium creatine phosphate dibasic tetrahydrate
磷酸肌酸二钠盐,Creatine phosphate disodium salt tetrahydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) 主要存在于脊椎动物的骨骼肌中,是测定肌酸激酶的底物,能够用于骨骼肌收缩过程中 ATP 的再生。 | |||
T20446 |
Creosol
|
Endogenous Metabolite | Metabolism |
Creosol 是内源性代谢产物的一种。 | |||
T4883 |
Creatine
Methylguanidoacetic acid,肌酸 |
Endogenous Metabolite | Metabolism |
Creatine (Methylguanidoacetic acid) 是一种内源性氨基酸代谢物,在细胞能量中发挥重要作用,尤其是在肌肉和大脑中。 | |||
T22300 |
Creatine monohydrate
Methylguanidoacetic acid monohydrate,一水肌酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Creatine monohydrate (Methylguanidoacetic acid monohydrate) 是磷酸原能量系统的关键参与者,尤其是在肌肉和大脑中。 Creatine monohydrate 是高强度、短期活动中 ATP 的主要来源。 | |||
T21977 |
p-Cresyl sulfate
|
Others | Others |
p-Cresyl Sulfate 是主要的尿毒症毒素,存在于慢性肾病患者的血液,来源于肝脏中酪氨酸和苯丙氨酸的代谢物。 | |||
TN5837 |
Creoside III
|
||
Creoside III 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5837,CAS号为 1038602-12-8。 | |||
TN1532 |
Crenulatin
|
BCL; Caspase | Apoptosis; Proteases/Proteasome |
Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, inhibitive effect in 25 mg/L and stimulative effect in 100 mg/L group, respectively; the mechanism is related to the alterations of Fas/Bcl-2 expression and caspase-3 activity. | |||
T29470 |
6-Allyl-o-cresol
AI3 17108,AI3-17108,AI317108 |
||
6-Allyl-o-cresol is a biochemical. | |||
TN2476 | 1,10:4,5-Diepoxy-7(11)-germacren-8-one | Others | Others |
1,10:4,5-Diepoxy-7(11)-germacren-8-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2476,CAS号为 32179-18-3。 | |||
TN3718 |
Creticoside C
|
Others | Others |
Creticoside C 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3718,CAS号为 53452-34-9。 | |||
TN3841 | Di-O-methylcrenatin | Others | Others |
Di-O-methylcrenatin是一种天然产物,属于蔷薇科石楠属,其产品编号为 TN3841,CAS号为 64121-98-8。Di-O-methylcrenatin可用作对照参考。 | |||
TN6002 |
Crenatine
1-Ethyl-4-methoxy-β-carboline |
||
Crenatine possesses antibacterial activity, it is more effective against Gram-positive than Gram-negative bacteria. | |||
TN6491 |
1,2-Epoxy-10(14)-furanogermacren-6-one
|
||
1,2-Epoxy-10(14)-furanogermacren-6-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6491,CAS号为 383368-24-9。 | |||
T11392 |
Germacrene D
|
Antibacterial | Microbiology/Virology |
Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles. Germacrene D is isolated from Bursera species. | |||
TN6974 |
(-)-Isobicyclogermacrenal
|
||
(-)-Isobicyclogermacrenal is a natural product. | |||
TN4866 | Pyracrenic acid | Others | Others |
Pyracrenic acid is a potent elastase inhibitor with an IC50 value of 1.5 mg/mL. Pyracrenic acid shows DPPH radical scavenging activity. It also shows significant cytotoxic activities against human cancer cells COLO 205 and AGS. | |||
T15011 | Creatine riboside | Others | Others |
Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer. | |||
T19934 |
Dehydrocrenatidine
TOP 3,TOP-3,O-Methylpicrasidine I,TOP3,Kumujian G |
Apoptosis; JAK | Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Dehydrocrenatidine (Kumujian G) 是 JAK 的抑制剂,可诱导细胞凋亡。 | |||
T21032 |
Germacrene D
1(10),4(14),5-Germacratriene |
||
Germacrene D, a natural essential oil, has antioxidant activity and cytotoxicity on tumor cells. | |||
T79958 |
Isocrenatoside
|
Angiotensin-converting Enzyme (ACE) | Metabolism |
Isocrenatoside (compound 6)为环状八肽,具有ACE抑制活性。该化合物可通过乙醇提取Microtoena prainiana茎部分离纯化。研究显示,1 mg/mL浓度下,Isocrenatoside的ACE抑制效率高达99.3%。 | |||
T81587 |
Oxocrebanine
|
||
Oxocrebanine, 阿朴啡类生物碱,Fissistigma poilanei(番荔枝科)所含。 | |||
T19515 |
Phosphocreatine dipotassium
Creatinephosphoric acid (dipotassium),Creatine phosphate (dipotassium) |
Others | Others |
Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives. | |||
TN1756 |
Hypocrellin C
|
Others | Others |
Hypocrellin C是一种天然产物,其产品编号为 TN1756,CAS号为 149457-83-0。Hypocrellin C可用作对照参考。 | |||
T72902 |
Acremonidin A
|
Others | Others |
Acremonidin A 是一种有效的钙调素(CaM)抑制剂,存在于Purpureocillium lilacinum 中。Acremonidin A 与人钙调素 (hCaM) 生物传感器 hCaM M124C mBBr 结合,Kd 为 19.40 nM。 | |||
TN7508 |
Germacrene B
|
Others | Others |
Germacrene B, a sesquiterpene identified in P. cablin (patchouli), demonstrates its presence within this botanical source. | |||
TN3439 |
Ardisicrenoside A
|
Others | Others |
Ardisicrenoside A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3439,CAS号为 160824-52-2。 | |||
TN3799 |
Dehydrocrebanine
|
Antifection | Microbiology/Virology |
Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng/ml. | |||
TN3275 |
8-Epicrepiside E
|
Others | Others |
8-Epicrepiside E是一种天然产物,属于菊科风毛菊属,其产品编号为 TN3275,CAS号为 93395-30-3。8-Epicrepiside E可用作对照参考。 | |||
T72731 |
Acremoxanthone C
|
Others | Others |
Acremoxantone C 是一种有效的钙调素(CaM)抑制剂,存在于 Purpureocillium lilacinum 中。Acremoxantone C 与人钙调素 (hCaM) 生物传感器 hCaM M124C mBBr 结合,Kd 为 18.25 nM。 | |||
T79973 |
Dehydrodiscretamine chloride
|
Others | Others |
Dehydrodiscretamine chloride作为AChE和BChE的双重抑制剂,展现了其抑制效力,其中对AChE的IC50为17.8 μM,对BChE的IC50为118.8 μM。此外,该化合物具备抗氧化活性,并可被应用于阿尔茨海默病相关研究。 | |||
T19122 |
3-Methylvaleric Acid
|
Others; Endogenous Metabolite | Metabolism; Others |
3-Methylvaleric Acid 是一种食用级香料,存在于烟草中。3-Methylvaleric Acid 可增强 CHO-K1细胞和HEK293细胞中的细胞内cAMP 积累和CRE-荧光素酶活性。 | |||
TN1334 |
7-Methoxyrosmanol
7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol |
cAMP | GPCR/G Protein |
7-Methoxyrosmanol (7-O-Methylrosmanol) 是一种酚类二萜,从迷迭香中分离得到,可抑制 PEPCK 和 G6Pase 启动子的 cAMP 反应。 | |||
T8152 |
6-Demethoxytangeretin
|
MAPK; ALK | Angiogenesis; MAPK; Tyrosine Kinase/Adaptors |
6-Demethoxytangeretin 是一种从柑橘分离的黄酮。它能够促进 CRE 介导的转录 (与海马神经元的学习和记忆相关)。它具有抗炎和抗过敏作用,通过间变性淋巴瘤激酶和丝裂原活化蛋白激酶途径抑制人肥大细胞中 IL-6 的产生和基因表达。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00522 |
Recombinase cre Protein, Enterobacteria phage P1, Recombinant (His & Myc)
cre,Recombinase cre |
Escherichia phage P1 | E. coli |
Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state. | |||
TMPY-02444 |
ATF2 Protein, Human, Recombinant (His & GST)
CREB2,CRE-BP1,CREB-2,TREB7,activa... |
Human | Baculovirus Insect Cells |
Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has ... | |||
TMPH-02614 |
CREB5 Protein, Mouse, Recombinant (His)
Creb5,Cyclic AMP-responsive element-binding protein... |
Mouse | E. coli |
Binds to the cAMP response element and activates transcription. | |||
TMPY-03627 |
CREB3L1 Protein, Human, Recombinant (aa 396-519, His)
OASIS,PSEC0238,cAMP responsive element binding protein 3-lik... |
Human | HEK293 Cells |
CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting prol... | |||
TMPY-03559 |
CREG1 Protein, Mouse, Recombinant (hFc)
cellular repressor of E1A-stimulated genes 1,Creg,A... |
Mouse | HEK293 Cells |
CREG1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is O88668. | |||
TMPY-00420 |
CRELD1 Protein, Mouse, Recombinant (hFc)
cysteine-rich with EGF-like domains 1,AI843811 |
Mouse | HEK293 Cells |
CRELD1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63 kDa and the accession number is Q91XD7. | |||
TMPJ-01197 |
CRELD2 Protein, Human, Recombinant (His)
Cysteine-Rich With EGF-Like Domain Protein 2,CRELD2 |
Human | HEK293 Cells |
Cysteine-Rich with EGF-Like Domain Protein 2 (CRELD2) is a secreted protein that is a member of the CRELD family. Human CRELD2 is synthesized as a 353 amino acid precursor protein with a signal peptide, a highly conserved domain rich in glutamic acid and tryptophan (WE) and EGF-like repeats. CRELD2 is ubiquitously expressed in many tissues. CRELD2 may interact with CHRNA4 and regulate transport of α4-β2 neuronal acetylcholine receptor. In addition, CRELD2 could be a novel mediator in regulating ... | |||
TMPK-00673 |
SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His)
SCG3,Secretogranin-3,UNQ2502/PRO5990,SGIII,Secr... |
Cynomolgus | HEK293 Cells |
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Cynomolgus... | |||
TMPH-02341 |
Endoglucanase 1 Protein, Hypocrea rufa, Recombinant (GST)
Endo-1,4-beta-D-glucanase 1,Endoglucanase 1 |
Hypocrea rufa | E. coli |
Has endoglucanase activity on carboxymethylcellulose (CMC). | |||
TMPH-02337 |
Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO)
hfb1,Hydrophobin-1,Hydrophobin I |
Hypocrea jecorina | E. coli |
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures. Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 23.5 kDa and the accession number is P52754. | |||
TMPH-00319 |
Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His)
yscF |
Burkholderia thailandensis | P. pastoris (Yeast) |
Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 11.9 kDa and the accession number is Q2T727. | |||
TMPH-00813 |
Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His)
Protein ORF2,Pro-secreted protein ORF2 |
HEV-1 | Baculovirus Insect Cells |
Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.; Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation. Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry. Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes. Hepatitis E virus gen... | |||
TMPH-02068 |
Secretogranin-1 Protein, Human, Recombinant (GST & His)
Secretogranin I,Chromogranin-B,Secretogran... |
Human | E. coli |
Secretogranin-1 Protein, Human, Recombinant (GST & His) is expressed in E. coli. | |||
TMPY-03420 |
CREG1 Protein, Mouse, Recombinant (His)
AA755314,Creg,cellular repressor of E1A-stimulated ... |
Mouse | HEK293 Cells |
CREG1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.9 kDa and the accession number is O88668. | |||
TMPY-03454 |
CRELD1 Protein, Mouse, Recombinant (His)
cysteine-rich with EGF-like domains 1,AI843811 |
Mouse | HEK293 Cells |
CRELD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is Q91XD7. | |||
TMPY-05426 |
CREG1 Protein, Human, Recombinant (His)
cellular repressor of E1A-stimulated genes 1,CREG |
Human | HEK293 Cells |
CREG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is O75629. | |||
TMPK-01122 |
SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)
SCG3,Secretogranin III,UNQ2502/PRO5990,Secre |
Human | HEK293 Cells |
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Human, Rec... | |||
TMPH-01158 |
CREBBP Protein, Human, Recombinant (GST)
CREBBP,CREB-binding protein,CBP |
Human | E. coli |
CREBBP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 40.7 kDa and the accession number is Q92793. | |||
TMPH-01165 |
CREB1 Protein, Human, Recombinant (His)
CREB-1,cAMP-responsive element-binding protein 1,Cy... |
Human | E. coli |
CREB1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02609 |
CREBZF Protein, Mouse, Recombinant (His)
Tyrosine kinase-associated leucine zipper protein LAZip,Zf,H... |
Mouse | Baculovirus Insect Cells |
Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. | |||
TMPH-03368 |
SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc)
Scg3,1B1075,Secretogranin-3,Secretogranin ... |
Rat | E. coli |
Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway. SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.2 kDa and the accessio... | |||
TMPY-03218 |
CRELD1 Protein, Human, Recombinant (His)
cysteine-rich with EGF-like domains 1,CIRRIN,AVSD2 |
Human | HEK293 Cells |
CRELD1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa and the accession number is A0A024R2G1. | |||
TMPY-04675 |
SG3/Secretogranin 3, Mouse, Recombinant (His)
AI385542,SgIII,1B1075,Chgd,secretogranin III |
Mouse | HEK293 Cells |
SG3/Secretogranin 3, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.4 kDa and the accession number is P47867-1. | |||
TMPY-00448 |
CRELD2 Protein, Mouse, Recombinant (hFc)
5730592L21Rik,cysteine-rich with EGF-like domains 2,C85758 |
Mouse | HEK293 Cells |
CRELD2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.8 kDa and the accession number is Q9CYA0. | |||
TMPH-02339 |
6GAL Protein, Hypocrea rufa, Recombinant (E. coli, His)
Endo-beta-1,6-galactanase,6GAL |
Hypocrea rufa | E. coli |
Hydrolyzes galactooligomers with a degree of polymerization higher than 3. Hydrolyzes radish root arabinogalactan-protein. Does not hydrolyze dextran, arabinan, starch, laminarin, beta-1,4- and beta-1,3-galactans, larch wood arabinogalactan or acid-insoluble polygalacturonic acid. | |||
TMPH-02338 |
HFBII Protein, Hypocrea jecorina, Recombinant (B2M & His & JD)
hfb2,Hydrophobin-2,Hydrophobin II |
Hypocrea jecorina | E. coli |
Responsible for spore hydrophobicity and protection. HFBII Protein, Hypocrea jecorina, Recombinant (B2M & His & JD) is expressed in E. coli expression system with N-10xHis-B2M-JD tag. The predicted molecular weight is 12.7 kDa and the accession number is P79073. | |||
TMPY-03494 |
CRELD2 Protein, Mouse, Recombinant (His)
5730592L21Rik,cysteine-rich with EGF-like domains 2,C85758 |
Mouse | HEK293 Cells |
CRELD2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q9CYA0. | |||
TMPY-03968 |
Secretogranin II Protein, Human, Recombinant (His)
EM66,SgII,SN,CHGC,secretogranin II |
Human | HEK293 Cells |
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KITL / kit ligand also belongs to the family of dimeric transmembrane growth factors. The soluble form of KIT ligand is a secreted protein. Mast cells are thought to participate in a variety of immune responses, such as parasite resistance and the allergic reaction. Mast cell devel... | |||
TMPY-03994 |
SG3/Secretogranin 3 Protein, Human, Recombinant (His)
secretogranin III,SGIII,UNQ2502/PRO5990 |
Human | HEK293 Cells |
SG3/Secretogranin 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.4 kDa and the accession number is AAH14539.1. | |||
TMPY-04761 |
Creatine kinase B Protein, Human, Recombinant (His)
HEL-S-29,CKBB,HEL-211,creatine kinase, brain,BCK,B-... |
Human | Baculovirus Insect Cells |
CKB(Creatine kinase B type) contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. It belongs to the ATP:guanido phosphotransferase family. CKB consists of a homodimer of two identical brain-type CK-B subunits. CKB is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CKB forms tightly coupled microcompartments ... | |||
TMPH-02340 |
6GAL Protein, Hypocrea rufa, Recombinant (His)
Endo-beta-1,6-galactanase,6GAL |
Hypocrea rufa | P. pastoris (Yeast) |
Hydrolyzes galactooligomers with a degree of polymerization higher than 3. Hydrolyzes radish root arabinogalactan-protein. Does not hydrolyze dextran, arabinan, starch, laminarin, beta-1,4- and beta-1,3-galactans, larch wood arabinogalactan or acid-insoluble polygalacturonic acid. | |||
TMPH-02069 |
Secretogranin-2 Protein, Human, Recombinant (GST & His)
Secretogranin-2,Chromogranin-C,Secretogran... |
Human | E. coli |
Secretogranin-2 Protein, Human, Recombinant (GST & His) is expressed in E. coli. | |||
TMPJ-00886 |
ATF1 Protein, Human, Recombinant (His)
Cyclic AMP-dependent transcription factor ATF-1,Activating t... |
Human | E. coli |
Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It also binds to the ... | |||
TMPH-02613 |
ATF-5 Protein, Mouse, Recombinant (His & Myc)
Transcription factor ATFx,Transcription factor-like protein ... |
Mouse | E. coli |
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcrip... | |||
TMPY-04380 |
DYRK3 Protein, Human, Recombinant (His & GST)
REDK,RED,DYRK5,dual-specificity tyrosine-(Y)-phosphorylation... |
Human | Baculovirus Insect Cells |
Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to theprotein kinase superfamily, CMGC Ser/Thr protein kinase family and MNB/DYRK subfamily. DYRKs are an emerging family of dual-specificity kinases that play key roles in cell proliferation, survival, and development. DYRK3 contains oneprotein kinase domain. Isoform 1 and isoform 2 of DYRK3 are highly expressed in testis and in hemat... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9087 |
Creatine-d3 hydrate
CREATINE-(METHYL-D3) MONOHYDRATE,肌氨酸酐-甲基-D3 一水合物 |
Endogenous Metabolite | Metabolism |
Creatine-d3 hydrate (CREATINE-(METHYL-D3) MONOHYDRATE) 是一种氘标记的肌酸水合物。其中肌酸水合物在肌肉和脑细胞的能量代谢中起着关键作用。 | |||
T19249 |
Creatinine-D3
NSC13123-D3,氘代肌酸酐 |
Others | Others |
Creatinine-D3 is a deuterium-labeled Creatinine which is a break-down product of creatine phosphate in muscle. | |||
TMID-0162 |
Creatinine-d5
|
||
Creatinine-d5 是 Creatinine 的氘代化合物。Creatinine 的 CAS 号为 60-27-5。Creatinine 由肌肉中磷酸肌酸分解产生。 | |||
TMID-0231 |
α,α,β,β-d4-Serotonin-Creatinine Sulfate Complex H2O
|
||
α,α,β,β-d4-Serotonin-Creatinine Sulfate Complex H2O 是 α,α,β,β-Serotonin-Creatinine Sulfate Complex H2O 的氘代化合物。 | |||
TMID-0096 |
P-CRESOL-d3 (METHYL-d3)
|
||
P-CRESOL-d3 (METHYL-d3) 是 P-CRESOL 的氘代化合物。P-CRESOL 的 CAS 号为 106-44-5。p-Cresol 是一种部分亲脂性部分,在正常条件下与血浆蛋白(接近 100%)强烈结合。对甲酚通过结合代谢,主要是硫酸化和葡萄糖醛酸化,但未结合的对甲酚至少部分通过尿液去除。 |