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Search Results for " cp-2 "

Targets Recommended: AChR

32

抑制剂 & 化合物

293

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T37196	5-AAM-2-CP	AChR	Neuroscience
	5-AAM-2-CP 是 Acetamiprid 的主要代谢物之一。 Acetamiprid 是一种 nAChR 激动剂，是一种新烟碱类杀虫剂。
T6685	Sulbactam sodium 舒巴坦钠,CP-45899-2	Antibacterial; Antibiotic	Microbiology/Virology
	Sulbactam sodium (CP-45899-2) 是一种竞争性、不可逆的 β-内酰胺酶抑制剂。它具有抗菌活性，抑制耐多药不动杆菌-鲍曼不动杆菌复合物。
T21648	CP-31398 dihydrochloride CP 31398 dihydrochloride	p53	Apoptosis
	CP-31398 dihydrochloride 是一种 p53 稳定剂，可稳定 p53 的活性构象并促进具有突变型或野生型 p53 的癌细胞系中的 p53 活性。
T1218	Cefoperazone sodium salt CP 52640-2,头孢哌酮钠,Cefoperazone sodium	Antibacterial; Antibiotic	Microbiology/Virology
	Cefoperazone sodium salt (CP 52640-2) 是一种半合成的头孢菌素，具有广谱抗菌活性。
T1603	Glipizide CP 28720,K 4024,格列吡嗪	Potassium Channel; PPAR; ABC	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Glipizide (CP 28720) 是一种有效的、具有口服活性的磺酰脲类抗糖尿病试剂 (anti-diabetic agent)，在 2 型糖尿病的研究中具有价值，但不适用于1 型糖尿病。Glipizide 是通过部分阻断郎格汉斯胰岛细胞中 ATP 敏感钾通道 (KATP)发挥活性。
T15259	Evatanepag CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Evatanepag (CP-533536 free acid) 是一种 EP2 受体选择性前列腺素 E2 (PGE2) 激动剂，可诱导局部骨形成，EC50 为 0.3 nM。它在大鼠骨折愈合模型中以单剂量局部给药时表现出愈合骨折的能力。
T9032	MGH-CP1	Others	Others
	MGH-CP1 是 TEAD2 (IC50:710 nM) 及 TEAD4 (IC50:672 nM) 自棕榈酰化抑制剂，口服有活性，可降低细胞内源性或异位表达的 TEAD 蛋白棕榈酰化水平。MGH-CP1 与 Lats1/2 缺失，是 Myc 的表达受到抑制，阻碍上皮细胞过度增殖，诱导细胞凋亡。
T24598	BrBzGCp2 p BrBzGSH(Cp)2,BBGC,pBrBzGSH(Cp)2,p-BrBzGSH(Cp)2,BBGD	Others	Others
	p-BrBzGSH(Cp)2 is a glyoxylase 1 inhibitor. In orthotopic mouse models, it acts by increasing DNA-AGEs, stimulating RAGE expression, and inhibiting brain tumor growth.
T35338	CP2	Histone Demethylase	Chromatin/Epigenetic
	CP2是一种环肽，能够抑制JmjC histone demethylases KDM4，对KDM4A 和KDM4C 的IC50分别为42 nM 和29 nM。
T31627	Englitazone sodium CP-72,467-2,D03996,CP-72467-2,Englitazone sodium (USAN)	Others	Others
	Englitazone sodium is an antidiabetic agent and a novel NSCA and KATP channel blocker.
T71262	AZD-8418	Others	Others
	AZD-8418 is an mGlu2 receptor positive allosteric modulators that attenuates nicotine-taking and nicotine-seeking behavior. Acute treatment with AZD8418 (0.37, 1.12, 3.73, 7.46, and 14.92 mg/kg) and AZD8529 (1.75, 5.83, 17.5, and 58.3 mg/kg) deceased nicotine self-administration and had no effect on food-maintained responding. Chronic treatment with AZD8418 attenuated nicotine self-administration, but tolerance to this effect developed quickly. The inhibition of nicotine self-administration by c...
T40295	Carindacillin sodium Carindacillin sodium,CP-15464-2,Carbenicillin indanyl sodium	Others	Others
	Carindacillin sodium, also known as Carbenicillin indanyl sodium, is an orally active, broad-spectrum antimicrobial agent. In vivo, it undergoes hydrolysis to Carbenicillin. Carindacillin sodium is specifically utilized in urinary tract infection research.
T74086	5-AMAM-2-CP	Others	Others
	5-AMAM-2-CP 是一种 Acetamiprid 的主要代谢产物。Acetamiprid 是一种广泛使用的新烟碱类杀虫剂，是nAChR 的激动剂。
T10870L	CP-547632	VEGFR; FGFR; PDGFR; BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	CP-547632是一种可口服且具有有效性、ATP 竞争性的血管内皮生长因子受体2（VEGFR-2 ）和碱性成纤维细胞生长因子（FGF）激酶F 双重抑制剂，IC50 分别为 11 nM 和 9 nM。CP-547632具有选择性，对 VEGFR2 和 bFGF 的选择性高于 EGFR，PDGFRβ 和相关的酪氨酸激酶 (TKs) 。 CP-547632具有抗肿瘤活性。
T6328	Desmethyl Erlotinib OSI-420,CP-473420,O-Desmethyl Erlotinib	EGFR; Drug Metabolite	Angiogenesis; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
	Desmethyl Erlotinib (CP-473420) 是 Erlotinib 的活性代谢物。Erlotinib 是 EGFR 酪氨酸激酶抑制剂。
T0758	Piroxicam 吡罗昔康,CP-16171	COX	Immunology/Inflammation; Neuroscience
	Piroxicam (CP-16171) 是一种非甾体抗炎剂，能够抑制COX 的活性，对人单核细胞 COX-1 和 COX-2 的IC50值分别为 47 和 25 μM。
T2398	Tofacitinib Citrate CP-690550 citrate,柠檬酸托法替尼,枸橼酸托法替尼,Tasocitinib citrate,Tofacitinib (CP-690550) Citrate	Apoptosis; Influenza Virus; JAK; Antibacterial; Antifungal	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Tofacitinib Citrate (CP-690550 citrate) 是 JAK1/2/3抑制剂，IC50分别为112，20 和 1 nM。它具有抗菌，抗真菌和抗病毒活性。
T31020	CP 461 OSI 461,UNII-68OJX9I7DT,CP-461,CP461	Apoptosis; PDE	Apoptosis; Metabolism
	CP 461 (UNII-68OJX9I7DT) 是一种特异性 PDE2A 抑制剂，是一种新型促凋亡化合物，能抑制环 GMP 磷酸二酯酶，但不能抑制环氧化酶-1 或-2。CP 461 在体外可抑制多种人类肿瘤细胞系的生长，并选择性地诱导癌细胞系而不是正常细胞凋亡。
T22689	CP94253 hydrochloride CP 94253 hydrochloride	Others; 5-HT Receptor	GPCR/G Protein; Neuroscience; Others
	CP94253 hydrochloride (CP 94253 hydrochloride) 是一种有效的、特异性的和中枢活性的 5-HT1B 受体激动剂，Ki 为 2 nM。5-HT1A、5-HT1D、5-HT1C 和 5-HT2 的 Ki 分别为 89、49、860 和 1600 nM 。
T17036	Tenidap CP-66248	COX; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Neuroscience
	Tenidap (CP-66248) 是选择性的 COX-1 和SLC26A3 抑制剂，具有具有抗炎，镇痛和抗风湿活性，抑制 COX-1 和COX-2 ，可抑制 DNA 和胶原蛋白的合成，抑制细胞增殖。
T37075	CB2R PAM Ec2la	Cannabinoid Receptor	GPCR/G Protein
	CB2R PAM 是一种口服活性大麻素 2 型受体（CB2Rs）阳性突变调节剂，它能增强 CP 55940 和 2-Arachidonylglycerol 刺激的 [35S]GTPγS 与 CB2 受体的结合，但在没有激动剂的情况下没有作用。CB2R PAM 在神经病理性疼痛小鼠模型中显示出抗损伤活性。
T6455	CP-91149	Phosphorylase	Metabolism
	CP91149 是GP (糖原磷酸化酶)的抑制剂，能够促进糖原的重新合成，但不会造成糖原的过度积累。它对2型糖尿病具有潜在的研究价值。
T31067	CP-601932 CP 601932,CP-601932 (free base),CP-601,927,UNII-VI5LR1EU47	Others	Others
	CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.
T31048	CP-320626 CP 320626	Others	Others
	CP-320626 is an effective inhibitor of glycogen phosphorylase A (LGPA) in the human liver and GPA in the human muscle. Can act synergistically with glucose. It is a possible target for the treatment of type 2 diabetes.
T10870	CP-547632 hydrochloride	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	CP-547632 hydrochloride is a well-tolerated and orally-bioavailable inhibitor of the VEGFR-2 and basic FGF kinases (IC50s: 11 nM and 9 nM) with antitumor efficacy.
T21875	CP-465022 (maleate)	Others	Others
	CP-465022 Maleate is a potent, selective, noncompetitive AMPA receptor antagonist with anticonvulsant activity. It effectively counters the Kainate-induced response in rat cortical neurons, exhibiting an IC 50 of 25 nM. As such, CP-465022 Maleate presents a valuable instrument for studying the involvement of AMPA receptors in various physiological and pathophysiological processes [1] [2].
T74000	CP-547632 TFA	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	CP-547632 TFA是一款口服效果显著的ATP競爭性抑制劑，针对VEGFR-2和FGF激酶具有高度选择性，IC50值分别为11 nM和9 nM。该化合物相较于EGFR和PDGFRβ，对VEGFR2和bFGF展现出更高的选择性，优于相关的酪氨酸激酶（TKs）。CP-547632 TFA还显示了显著的抗肿瘤活性。
T84898	CP 122721 hydrochloride	Others	Others
	CP 122721 hydrochloride是一种有效的非肽选择性neurokinin NK1非肽拮抗剂，针对IM-9细胞中表达的人NK1受体展示出9.8的pIC50值，具备抗焦虑和抗抑郁样效应。
T38204	GAT229	Others	Others
	GAT229 is a positive allosteric modulator of cannabinoid receptor 1 (CB1) and the S-(-) enantiomer of the CB1 modulator GAT211. It does not activate the receptor on its own but enhances the binding and activity of CB agonists. GAT229 (1 μM) enhances the binding of the CB1 full agonist CP 55,940 to CHO cells expressing human recombinant CB1 (hCB1), as well as the activity of 2-arachidonoyl glycerol , arachidonoyl ethanolamide , and CP 55,940 in arrestin2 recruitment assays and increases ERK1/2 an...
T83821	Thymidine-5'-O-(α,β-methylene)diphosphate sodium α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP	Others	Others
	TMP-CP（Thymidine-5’-O-(α,β-methylene)diphosphate）是TDP的一种水解稳定衍生物，同时也是一种thymidine kinase抑制剂（Ki = 23 µM）。它已被用作α,β-methylene-2’-deoxythymidine 5’-triphosphate合成的前体，该合成物是DNA polymerase的一种不可切割底物。
T4246L	Varenicline	Others	Others
	Varenicline (CP 526555) 是一种有效的α4β2 nAChR 烟碱乙酰胆碱受体的部分激动剂，EC50值为2.3 μM。Varenicline 是 α3β4 nAChR 和 α7 nAChR 乙酰胆碱受体的完全激动剂，EC50值分别为 55 μM 和 18 μM。Varenicline 是一种基于胞嘧啶结构的烟碱配体，具有戒烟治疗的潜力。
T61607	Laquinimod sodium	Others	Others
	Laquinimod (ABR-215062) sodium 是一种可口服的羧酰胺衍生物，是一种有效的免疫调节剂，可防止中枢神经系统的神经变性和炎症。Laquinimod sodium 减少星形胶质细胞NF-κB 的活化以防止铜酮 (Cuprizone) 诱导的脱髓鞘。Laquinimod sodium 具有用于多发性硬化症 (MS；RRMS 或 CPMS) 的复发缓解 (RR) 和慢性进行性 (CP) 形式以及神经退行性疾病研究的潜力。

化合物

Cat.No: T37196

Target: AChR

Sulbactam sodium

Cat.No: T6685

Synonym: 舒巴坦钠,CP-45899-2

Target: Antibacterial, Antibiotic

CP-31398 dihydrochloride

Cat.No: T21648

Synonym: CP 31398 dihydrochloride

Target: p53

Cefoperazone sodium salt

Cat.No: T1218

Synonym: CP 52640-2,头孢哌酮钠,Cefoperazone sodium

Target: Antibacterial, Antibiotic

Cat.No: T1603

Synonym: CP 28720,K 4024,格列吡嗪

Target: Potassium Channel, PPAR, ABC

Cat.No: T15259

Synonym: CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸

Target: Prostaglandin Receptor

Cat.No: T9032

Target: Others

Cat.No: T24598

Synonym: p BrBzGSH(Cp)2,BBGC,pBrBzGSH(Cp)2,p-BrBzGSH(Cp)2,BBGD

Target: Others

Cat.No: T35338

Target: Histone Demethylase

Englitazone sodium

Cat.No: T31627

Synonym: CP-72,467-2,D03996,CP-72467-2,Englitazone sodium (USAN)

Target: Others

Cat.No: T71262

Target: Others

Carindacillin sodium

Cat.No: T40295

Synonym: Carindacillin sodium,CP-15464-2,Carbenicillin indanyl sodium

Target: Others

Cat.No: T74086

Target: Others

Cat.No: T10870L

Target: VEGFR, FGFR, PDGFR, BTK

Desmethyl Erlotinib

Cat.No: T6328

Synonym: OSI-420,CP-473420,O-Desmethyl Erlotinib

Target: EGFR, Drug Metabolite

Cat.No: T0758

Synonym: 吡罗昔康,CP-16171

Target: COX

Tofacitinib Citrate

Cat.No: T2398

Synonym: CP-690550 citrate,柠檬酸托法替尼,枸橼酸托法替尼,Tasocitinib citrate,Tofacitinib (CP-690550) Citrate

Target: Apoptosis, Influenza Virus, JAK, Antibacterial, Antifungal

Cat.No: T31020

Synonym: OSI 461,UNII-68OJX9I7DT,CP-461,CP461

Target: Apoptosis, PDE

CP94253 hydrochloride

Cat.No: T22689

Synonym: CP 94253 hydrochloride

Target: Others, 5-HT Receptor

Cat.No: T17036

Synonym: CP-66248

Target: COX, DNA/RNA Synthesis

Cat.No: T37075

Synonym: Ec2la

Target: Cannabinoid Receptor

Cat.No: T6455

Target: Phosphorylase

Cat.No: T31067

Synonym: CP 601932,CP-601932 (free base),CP-601,927,UNII-VI5LR1EU47

Target: Others

Cat.No: T31048

Synonym: CP 320626

Target: Others

CP-547632 hydrochloride

Cat.No: T10870

Target: FGFR

CP-465022 (maleate)

Cat.No: T21875

Target: Others

Cat.No: T74000

Target: VEGFR

CP 122721 hydrochloride

Cat.No: T84898

Target: Others

Cat.No: T38204

Target: Others

Thymidine-5'-O-(α,β-methylene)diphosphate sodium

Cat.No: T83821

Synonym: α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP

Target: Others

Cat.No: T4246L

Target: Others

Laquinimod sodium

Cat.No: T61607

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02096	TACI Protein, Human, Recombinant (His) RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...	Human	HEK293 Cells
	TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His) Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...	Human	E. coli
	KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-02011	CD96 Protein, Human, Recombinant (His) CD96 molecule,TACTILE	Human	HEK293 Cells
	CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-01442	DMBT1 Protein, Human, Recombinant (His) GP340,deleted in malignant brain tumors 1,muclin	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPY-01717	VEGF164 Protein, Mouse, Recombinant vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子	Mouse	Baculovirus Insect Cells
	VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-01613	Periostin/OSF-2 Protein, Mouse, Recombinant (His) A630052E07Rik,OSF-2,Osf2,PLF,AI74...	Mouse	HEK293 Cells
	Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Protein T1,suppression of tumorigenicity 2,Ly84,DER...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His) SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-00751	TrkB Protein, Human, Recombinant (His) trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...	Human	HEK293 Cells
	TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-05288	PLGF/PGF Protein, Human, Recombinant (aa 19-149) PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...	Human	E. coli
	PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-04844	BTN3A1 Protein, Human, Recombinant (His) BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2...	Human	HEK293 Cells
	BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His) KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL...	Human	E. coli
	KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-02820	SDF-1/CXCL12 Protein, Human, Recombinant (isoform a) SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1	Human	E. coli
	SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST) v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01935	c-Kit Protein, Human, Recombinant (His) PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...	Human	HEK293 Cells
	c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-04644	PDGFB Protein, Human, Recombinant (His) platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...	Human	P. pastoris (Yeast)
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-01985	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated FCGR2,FCGR21,CD32A,FCG2,...	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04356	GSK3B Protein, Human, Recombinant (His) glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β	Human	Baculovirus Insect Cells
	GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02500	YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) Gp39,AW208766,Brp39,chitinase 3 like 1	Mouse	HEK293 Cells
	YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
TMPY-05414	NKG2D/CD314 Protein, Mouse, Recombinant (hFc) D6H12S2489E,NKG2-D,killer cell le...	Mouse	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-01871	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) interleukin 5 receptor, alpha,IL5R,CD125,CDw12<...	Human	HEK293 Cells
	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293) HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...	Human	HEK293 Cells
	GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His) IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His) KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...	Human	E. coli
	KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-00747	Nectin-2 Protein, Human, Recombinant (His) PVRR2,Nectin-2,poliovirus receptor-related...	Human	HEK293 Cells
	Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-04051	c-Kit Protein, Human, Recombinant (hFc) SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene h...	Human	HEK293 Cells
	c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
TMPY-05427	CD19 Protein, Human, Recombinant (hFc) CVID3,B4,CD19 molecule	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His) TGFR-2,TGF-beta type II receptor,Transforming growt...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-00127	M-CSF/CSF1 Protein, Human, Recombinant 集落刺激因子,CSF-1,MCSF,M-CSF,colony stimulating factor 1 (macroph...	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His) NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2	Human	E. coli
	KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-02432	VEGF164 Protein, Rat, Recombinant 血管内皮生长因子,vascular endothelial growth factor A	Rat	Baculovirus Insect Cells
	VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-02231	TrkB Protein, Mouse, Recombinant (His) trk-B,neurotrophic tyrosine kinase, receptor, type 2	Mouse	HEK293 Cells
	TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
TMPY-02367	Neuropilin-1 Protein, Human, Recombinant (isoform b, His) neuropilin 1,NRP,VEGF165R,BDCA4,Neuropilin-1,NP1,CD304	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-04829	G-CSF Protein, Human, Recombinant G-CSF,colony stimulating factor 3 (granulocyte),集落刺激因子,CSF3O...	Human	HEK293 Cells
	G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
TMPY-00871	LAYN Protein, Human, Recombinant (hFc) layilin	Human	HEK293 Cells
	LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
TMPY-01199	CD74 Protein, Human, Recombinant (His) II,DHLAG,Ia-GAMMA,CD74 molecule, major histocompatibility co...	Human	HEK293 Cells
	CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
TMPY-00005	FGF-8a Protein, Human, Recombinant fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-03425	Tau Protein, Human, Recombinant (His) PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as...	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPY-02358	CD98 Protein, Mouse, Recombinant (His) NACAE,AI314110,Ly-m10,Cd98,Mgp-2hc,4F2HC,L...	Mouse	HEK293 Cells
	CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2.
TMPY-02971	CLEC10A Protein, Human, Recombinant (hFc) HML2,CD301,CLECSF13,HML,MGL,C-type lectin domain fa...	Human	HEK293 Cells
	CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPY-05586	CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated TMIGD2,IGPR-1,transmembrane and immunoglobulin doma...	Human	HEK293 Cells
	The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu...
TMPY-00748	Nectin-2 Protein, Human, Recombinant PRR2,Nectin-2,PVRR2,poliovirus re...	Human	HEK293 Cells
	Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-00392	PAM Protein, Human, Recombinant (His) PAL,peptidylglycine alpha-amidating monooxygenase,peptidylgl...	Human	HEK293 Cells
	PAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 94.4 kDa and the accession number is P19021-2.
TMPY-01726	Neuroligin-1 Protein, Human, Recombinant (His) neuroligin 1,NL1	Human	HEK293 Cells
	Neuroligin-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72 kDa and the accession number is Q8N2Q7-2.
TMPY-03597	VIP Protein, Human, Recombinant (His) PHM27,vasoactive intestinal peptide	Human	HEK293 Cells
	VIP, or vasoactive intestinal peptide, is a neuropeptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, and it exerts its actions through three G-protein-coupled receptors (PAC1, VPAC1, and VPAC2). VIP is synthesized by trophoblast cells; it regulates trophoblast cell function and interaction with the major immune cell populations present in the pregnant uterus.
TMPY-03366	DPEP2 Protein, Human, Recombinant (hFc) dipeptidase 2,MBD2	Human	HEK293 Cells
	DPEP2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q9H4A9-2.
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重组蛋白

Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

Cat.No: TMPY-00891

Species: Human

Expression System: HEK293 Cells

TACI Protein, Human, Recombinant (His)

Cat.No: TMPY-02096

Species: Human

Expression System: HEK293 Cells

KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Cat.No: TMPY-04113

Species: Human

Expression System: E. coli

CD96 Protein, Human, Recombinant (His)

Cat.No: TMPY-02011

Species: Human

Expression System: HEK293 Cells

DMBT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01442

Species: Human

Expression System: HEK293 Cells

VEGF164 Protein, Mouse, Recombinant

Cat.No: TMPY-01717

Species: Mouse

Expression System: Baculovirus Insect Cells

FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

Cat.No: TMPY-00341

Species: Human

Expression System: HEK293 Cells

Periostin/OSF-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01613

Species: Mouse

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Cat.No: TMPJ-00850

Species: Mouse

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (CLU34, His)

Cat.No: TMPY-01691

Species: Human

Expression System: HEK293 Cells

TrkB Protein, Human, Recombinant (His)

Cat.No: TMPY-00751

Species: Human

Expression System: HEK293 Cells

PLGF/PGF Protein, Human, Recombinant (aa 19-149)

Cat.No: TMPY-05288

Species: Human

Expression System: E. coli

BTN3A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04844

Species: Human

Expression System: HEK293 Cells

KRAS Protein, Human, Recombinant (G12D, His)

Cat.No: TMPY-06056

Species: Human

Expression System: E. coli

SDF-1/CXCL12 Protein, Human, Recombinant (isoform a)

Cat.No: TMPY-02820

Species: Human

Expression System: E. coli

C-ABL/ABL1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

c-Kit Protein, Human, Recombinant (His)

Cat.No: TMPY-01935

Species: Human

Expression System: HEK293 Cells

PDGFB Protein, Human, Recombinant (His)

Cat.No: TMPY-04644

Species: Human

Expression System: P. pastoris (Yeast)

CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-01985

Species: Human

Expression System: HEK293 Cells

GSK3B Protein, Human, Recombinant (His)

Cat.No: TMPY-04356

Species: Human

Expression System: Baculovirus Insect Cells

YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02500

Species: Mouse

Expression System: HEK293 Cells

NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-05414

Species: Mouse

Expression System: Baculovirus Insect Cells

IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

Cat.No: TMPY-01871

Species: Human

Expression System: HEK293 Cells

GDNF Protein, Human, Recombinant (HEK293)

Cat.No: TMPY-02792

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01359

Species: Human

Expression System: HEK293 Cells

KRAS Protein,Human, Recombinant (Q61H, His)

Cat.No: TMPY-01888

Species: Human

Expression System: E. coli

Nectin-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00747

Species: Human

Expression System: HEK293 Cells

c-Kit Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04051

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05427

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00335

Species: Mouse

Expression System: HEK293 Cells

M-CSF/CSF1 Protein, Human, Recombinant

Cat.No: TMPY-00127

Species: Human

Expression System: HEK293 Cells

KRAS Protein,Human,Recombinant(G12C & Q61H, His)

Cat.No: TMPY-04116

Species: Human

Expression System: E. coli

VEGF164 Protein, Rat, Recombinant

Cat.No: TMPY-02432

Species: Rat

Expression System: Baculovirus Insect Cells

TrkB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02231

Species: Mouse

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant

Cat.No: TMPY-00850

Species: Human

Expression System: HEK293 Cells

Neuropilin-1 Protein, Human, Recombinant (isoform b, His)

Cat.No: TMPY-02367

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00849

Species: Human

Expression System: HEK293 Cells

G-CSF Protein, Human, Recombinant

Cat.No: TMPY-04829

Species: Human

Expression System: HEK293 Cells

LAYN Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00871

Species: Human

Expression System: HEK293 Cells

CD74 Protein, Human, Recombinant (His)

Cat.No: TMPY-01199

Species: Human

Expression System: HEK293 Cells

FGF-8a Protein, Human, Recombinant

Cat.No: TMPY-00005

Species: Human

Expression System: E. coli

Tau Protein, Human, Recombinant (His)

Cat.No: TMPY-03425

Species: Human

Expression System: E. coli

CD98 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02358

Species: Mouse

Expression System: HEK293 Cells

CLEC10A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02971

Species: Human

Expression System: HEK293 Cells

CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05586

Species: Human

Expression System: HEK293 Cells

Nectin-2 Protein, Human, Recombinant

Cat.No: TMPY-00748

Species: Human

Expression System: HEK293 Cells

PAM Protein, Human, Recombinant (His)

Cat.No: TMPY-00392

Species: Human

Expression System: HEK293 Cells

Neuroligin-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01726

Species: Human

Expression System: HEK293 Cells

VIP Protein, Human, Recombinant (His)

Cat.No: TMPY-03597

Species: Human

Expression System: HEK293 Cells

DPEP2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03366

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T35915	Erlotinib-13C6 Erlotinib-13C6
	Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]...

同位素标记化合物

Cat.No: T35915

Synonym: Erlotinib-13C6

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