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Search Results for " cnb "
Targets Recommended: Others

1

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T79311 CNBCA

Others Others
CNBCA是一种有效的SHP2酶抑制剂,具有选择性和竞争性,IC50值为0.87 μM。该化合物可结合SHP2全长蛋白并抑制其酶活性,进而阻止Akt和ERK1/2的磷酸化,以及抑制BT474和MDA-MB468乳腺癌细胞的生长。CNBCA主要用于乳腺癌的研究。

化合物

CNBCA
Cat.No: T79311
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-02964 Calcineurin B/PPP3R1 Protein, Human, Recombinant (His)

protein phosphatase 3, regulatory subunit B, alpha,CNB

Human Baculovirus Insect Cells
PPP3R1 belongs to the calcineurin regulatory subunit family. It is a regulatory subunit of calcineurin. Calcineurin is composed of two subunits: calcineurin A (CnA) and calcineurin B (CnB). Dephosphorylation of the nuclear factor of activated T-cells (NF-AT) by Calcineurin is essential for NF-AT activation, nuclear translocation, and early gene expression in T-cells. PPP3R1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase which takes a vital part in the T cell activatio...
TMPY-02375 acnB Protein, E. coli, Recombinant

yacI,yacJ

E. coli E. coli
Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to SoxRS-mediated activation, whereas acnB encodes the major aconitase that is synthesized earlier in the growth cycle than AcnA. It is concluded that AcnB is the major citric acid cycle enzyme. Aconitate hydratase 2 (acnB) catalyzes the isomerization of citrate to isocitrate via cis-a...

重组蛋白

Calcineurin B/PPP3R1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02964
Species: Human
Expression System: Baculovirus Insect Cells
acnB Protein, E. coli, Recombinant
Cat.No: TMPY-02375
Species: E. coli
Expression System: E. coli
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