43
3
19
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82701 |
CMV pp65(13-27)
|
||
CMVpp65(13-27)是一种源自人巨细胞病毒65k下层基质磷蛋白的氨基酸残基13至27的生物活性肽。它含有的九个氨基酸序列(LGPISGHVL)与主要组织相容性复合物H2-Dd T细胞表位的共有结合基序匹配。 | |||
T0718 |
Brivudine
Bromovinyldeoxyuridine,BVDU,溴夫定 |
Others; HSV | Microbiology/Virology; Others |
Brivudine (BVDU) 是胸苷类似物,有抗病毒活性,用于早期急性带状疱疹的研究。 | |||
T38514 |
PMEDAP
|
Others; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
PMEDAP 是有效的人类免疫缺陷病毒 (HIV) 复制抑制剂。它具有抗小鼠巨细胞病毒活性。它有效抑制莫罗尼鼠肉瘤病毒诱导的肿瘤形成和相关死亡率。 | |||
T9648 |
SIRT1-IN-1
|
Antiviral; Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation |
SIRT1-IN-1 是一种选择性的 SIRT1 抑制剂,IC50 为 205 nM。 SIRT1-IN-1 是一种具有抗病毒活性的巨细胞病毒 (CMV) 抑制剂。 | |||
T15235 |
Enocitabine
|
Nucleoside Antimetabolite/Analog; HCV Protease; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome |
Enocitabine 是一种核苷类似物,抑制 DNA 复制剂。Enocitabine 抑制人巨细胞病毒的复制,显示出抗白血病和抗病毒活性。 | |||
T14324 |
Artemisone
BAY 44-9585,Artemifone,青蒿酮 |
Others; Parasite | Microbiology/Virology; Others |
Artemisone (BAY 44-9585) 是一种半合成的有效抗疟疾剂,还是一种人CMV 的有效抑制剂,可抑制多种P. falciparum,平均IC50值为 0.83 nM。 | |||
T7659 |
Bisindolylmaleimide IV
|
Others; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Others |
Bisindolylmaleimide IV 是一种蛋白激酶 C 细胞渗透抑制剂,其 IC50范围为 0.1-0.55 μM。它也抑制 PKA,IC50范围为3.1-11.8 μM。在细胞培养中,它有效抑制人巨细胞病毒(HCMV)复制,IC50为 0.2 μM。 | |||
T2162 |
Maribavir
BW1263W94,GW257406X,Benzimidavir,马立巴韦,1263W94 |
Others; HCV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
Maribavir (GW257406X) 是一种可口服的苯并咪唑核苷化合物,具有抗巨细胞病毒的活性。 | |||
T5396 |
Letermovir
AIC246,MK-8828,莱莫维韦 |
Others; HCV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
Letermovir (AIC246) 是一种新型抗 CMV 抑制剂,靶向病毒末端酶,抑制其活性。 | |||
T1533 |
Valganciclovir hydrochloride
Valganciclovir HCl,Valcyt,缬更昔洛韦盐酸盐,Valcyte |
Others; Antiviral | Immunology/Inflammation; Others |
Valganciclovir hydrochloride (Valganciclovir HCl) 是 ganciclovir 的原药,具有抗巨细胞病毒活性,可抑制病毒 DNA 聚合酶和病毒复制。 | |||
T8972 |
FIT-039
|
Others; DNA/RNA Synthesis; CDK; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
FIT-039 是一种选择性和 ATP 竞争性的口服活性 CDK9 抑制剂,对CKD9/cyclin T1的IC50为 5.8 μM。它抑制HSV-1(IC50为 0.69 μM),HSV-2,人腺病毒和人CMV 的复制。它可抑制耐药性HSV 和其他 DNA 病毒,是有前途的抗病毒药物。 | |||
T6593 |
ML324
|
Histone Demethylase; Others; HSV | Chromatin/Epigenetic; Microbiology/Virology; Others |
ML324 是 jumonji 组蛋白去甲基化酶的特异性抑制剂,IC50值为920 nM。 | |||
TQ0095 |
Brincidofovir
CMX001,HDP-CDV |
Others; Antiviral; HSV | Immunology/Inflammation; Microbiology/Virology; Others |
Brincidofovir (HDP-CDV) 是 Cidofovir 的一种具有口服活性的亲脂性形式的前体药物,是一种口服长效的抗病毒药物,有广泛的抗 DNA 病毒活性。 | |||
T6244 |
Cidofovir
HPMPC,GS 0504,西多福韦,(S)-HPMPC |
Others; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。 | |||
T39477 |
Ca-DTPA trisodium salt hydrate
Ca-DTPA trisodium salt hydrate,Calcium trinatrium diethylenetriaminepentaacetic acid hydrate |
Others | Others |
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) 是螯合剂和有用的解毒剂,如急性镉中毒。它是一种无毒的 CMV 复制抑制剂。 | |||
T8736 |
Cidofovir dihydrate
HPMPC,(S)-HPMPC,GS 0504,西多福韦二水合物 |
Others | Others |
Cidofovir dihydrate (HPMPC) 是注射型巨细胞病毒 DNA 聚合酶抑制剂,通过选择性抑制病毒 DNA 聚合酶来抑制 CMV 复制,从而阻止病毒复制和转录。 | |||
T0964 |
Floxuridine
氟尿苷,5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640 |
Apoptosis; Nucleoside Antimetabolite/Analog; Others; DNA/RNA Synthesis; Antibacterial; HSV | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Floxuridine (FUDR) 是一种嘧啶类似物,也是一种抗肿瘤代谢物。它抑制胸苷酸合成酶,导致 DNA 合成中断和细胞毒性。它是一种可诱导细胞凋亡的金黄色葡萄球菌感染抑制剂 ,具有抗HSV 和CMV 病毒的作用。 | |||
T0688 |
Ganciclovir
BW 759,更昔洛韦,RS-21592,2'-Nor-2'-deoxyguanosine |
Nucleoside Antimetabolite/Analog; Others; Antibiotic; Antifection; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Ganciclovir (2'-Nor-2'-deoxyguanosine) 是核苷类似物和口服抗病毒药物,对CMV 具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。 | |||
T22337 |
Ganciclovir sodium
RS-21592 sodium,Cytovene IV sodium,2'-Nor-2'-deoxyguanosine sodium,BW 759 sodium,更昔洛韦钠 |
Nucleoside Antimetabolite/Analog; Others; Antifection; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Ganciclovir sodium (Cytovene IV sodium) 是核苷类似物和口服抗病毒药物,具有抗病毒活性,尤其是针对巨细胞病毒和单纯疱疹病毒 1 型。 | |||
TP1758L |
LCMV gp33-41 acetate
LCMV gp33-41 acetate(151705-84-9 Free base) |
Others | Others |
LCMV gp33-41 acetate 是淋巴细胞性脉络丛脑膜炎病毒的序列,受主要组织相容性复合体 I 类 H-2Db 限制,呈递给细胞毒性 T 淋巴细胞。 | |||
T75982 |
LCMV gp33-41 TFA
|
||
LCMV gp33-41 (TFA)是一种带有羧基延伸的11-aa长肽,作为淋巴细胞脉络丛脑膜炎病毒序列,在MHC I类H-2Db分子的限制下,能够被呈递给细胞毒性T淋巴细胞。 | |||
T39863 |
LCMV GP (61-80)
|
||
LCMV GP (61-80) is a peptide fragment derived from LCMV glycoprotein (GP) and corresponds to amino acids 61-80. This specific epitope, LCMV GP (61-80), has the ability to elicit CD4+ T-cell response. | |||
TP1629 |
LCMV gp33-41 (TFA) (151705-84-9 free base)
LCMV gp33-41 (TFA) |
||
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes[1]. | |||
TP1758 |
LCMV gp33-41
|
||
LCMV gp33-41, the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes.This is the H-2Db restricted epitope derived from the lymphocytic | |||
T10445 |
B220
|
HSV | Microbiology/Virology |
B220 是一种能抑制 HSV-1,HSV-2 和人巨细胞病毒 (CMV) 生长的抗病毒剂。 | |||
T9289 |
Phosphonoformic acid trisodium salt hexa
Sodium phosphonatoformate hexahydrate,foscarnet sodium hexahydrate,膦甲酸钠六水合物 |
Others | Others |
Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) 是一种用于治疗 CMV 视网膜炎的抗病毒药物。 | |||
T70514 |
Ganciclovir monophosphonate
|
Others | Others |
Ganciclovir monophosphonate is a synthetic analog of 2'-deoxy-guanosine which is used to treat or prevent cytomegalovirus (CMV) infections. It inhibits the replication of human CMV with an IC50 value of 0.01 μM and is effective against strains of CMV from human, monkey, mouse, and guinea pig. | |||
T73749 |
Fomivirsen
|
Others | Others |
Fomivirsen (ISIS-2922 free base)为一种21 mer磷酸硫寡核苷酸反义药物。作为抗巨细胞病毒视网膜炎(CMV)研究的重要试剂,通过结合并降解CMV immediate-early 2蛋白的mRNA,Fomivirsen有效抑制病毒复制。 | |||
T39068 |
Fomivirsen sodium
|
Others | Others |
Fomivirsen sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein (required for viral replication), thus providing bioactive effects for CMV retinitis by inhibition of virus proliferation. | |||
T68495 |
Ganciclovir triphosphate
|
Others | Others |
Ganciclovir triphosphate is a synthetic analog of 2'-deoxy-guanosine which is used to treat or prevent cytomegalovirus (CMV) infections. It inhibits the replication of human CMV with an IC50 value of 0.01 μM and is effective against strains of CMV from human, monkey, mouse, and guinea pig. | |||
T41013 |
Ganciclovir mono-O-acetate
|
Others | Others |
Ganciclovir mono-O-acetate is a derivative of Ganciclovir, an orally active antiviral agent with activity against CMV. It belongs to the group of nucleoside analogues. | |||
T77168 | Sevirumab | ||
Sevirumab (MSL-109) 是一种人抗巨细胞病毒 (CMV)IgG1中和单克隆抗体。Sevirumab 识别CMVgH 复合物,抑制CMV 复制,EC50为 0.3 μg/mL。 | |||
TQ0030 |
Tomeglovir
托美洛韦,BAY 38-4766 |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV). | |||
T77146 | Regavirumab | ||
Regavirumab (MCA C23)为针对巨细胞病毒(CMV)、人血清白蛋白(HSA)及氨基乙酸的人源单克隆抗体。 | |||
T62309 |
Antiviral agent 14
|
Others | Others |
Antiviral agent 14 是一种抗病毒剂,能够抑制烟草花叶病毒 (TMV) (EC50: 135.5 μg/mL),和黄瓜花叶病毒 (CMV) (EC50: 178.6 μg/mL)。 | |||
T27963 |
Lysine Orotate
|
Others | Others |
Lysine Orotate is an inhibitor of viral replication, especially useful to treat the Herpes family of viruses which includes Herpes Simplex 1 and 2 , CMV, EBV and Varicella. | |||
T15028 |
Cyclopropavir
MBX-400,Filociclovir,ZSM-I-62 |
Others | Others |
Cyclopropavir (Filociclovir; MBX-400) is a compound of broad-spectrum anti-herpesvirus. It has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 (EC50s: 0.7 μM to 8 μM). | |||
T61259 |
Valganciclovir
|
Others | Others |
Valganciclovir 是ganciclovir 的原药,具有抗巨细胞病毒CMV 感染的活性。 | |||
T71066 |
Cidofovir sodium
|
Others | Others |
Cidofovir sodium is the salt form of Cidofovir, a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor that is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis in people with AIDS. The mechanism of action of cidofovir is as a DNA Polymerase Inhibitor. The chemical classification of cidofovir anhydrous is Nucleoside Analog. | |||
T84893 |
Senexin A hydrochloride
|
Others | Others |
Senexin A hydrochloride是一种专门针对CDK8/19(IC50为280 nM,针对CDK8)的抑制剂,同时针对p21转录活性下游展现抑制作用。该化合物特异性抑制由p21诱导的转录活性,而不干扰p21的其他生物功能。此外,Senexin A hydrochloride能够抑制CMV-GFP引发的活性及p21激活的、具NF-κB依赖性启动子的表达。 | |||
T61801 |
HIV-1 inhibitor-35
|
Others | Others |
HIV-1 inhibitor-35 (compound 74) is a highly potent inhibitor of the HIV-1 virus, exhibiting EC50 values of 80 nM and 70 nM for LTR and CMV, respectively, in HEK293 cells. Additionally, HIV-1 inhibitor-35 demonstrates inhibitory activity against HepG2 liver cancer cells, with a CC50 value of 40 nM. Moreover, HIV-1 inhibitor-35 shows promise as a potential HIV-1 latency reversing agent [1]. | |||
T60488 |
Ganciclovir hydrate
|
Others | Others |
Ganciclovir (BW 759) hydrate 是一种核苷类似物,是具有口服活性的抗病毒剂,显示出抗巨细胞病毒活性。Ganciclovir hydrate 对疱疹病毒和其他一些 DNA 病毒也具有体外抗病毒活性。Ganciclovir hydrate 在体外抑制人类疱疹病毒 (HSV 1 型和 2 型,CMV) 和腺病毒血清型1、2、4、6、8、10、19、22 和 28 的复制。Ganciclovir hydrate 对猫疱疹病毒 1 型 (FHV-1) 的 IC50为 5.2 μM,可扩散到大脑。 | |||
T35696 |
Olomoucine II
|
Others | Others |
Olomoucine II is an inhibitor of cyclin-dependent kinases (CDKs; IC50s = 7.6, 0.1, 19.8, 0.45, and 0.06 μM for Cdk1, -2, -4, -7, and -9, respectively).1It is selective for CDKs over 10 additional kinases (IC50s = >100 μM for all) but does inhibit ERK2 (IC50= 32 μM) and the ATP-binding cassette transporter B1 (ABCB1; IC50= 6.4 μM).1,2Olomoucine II inhibits proliferation of a variety of cancer cells, including those expressing wild-type p53 or mutant p53 (mean IC50s = 7.4 and 10.1 μM, respectively... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1068 |
Tricin
|
Others; CDK | Cell Cycle/Checkpoint; Others |
Tricin 是米糠中大量存在的一种天然类黄酮。它通过抑制 CDK9 来抑制HCMV 的复制。它通过上调 FAK 靶向 microRNA-7 的表达来抑制 C6 胶质瘤细胞的增殖和侵袭。 | |||
T3342 |
Xanthohumol
|
Apoptosis; Others; Influenza Virus; COX; Acyltransferase; HSV | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; Others |
Xanthohumol 是从啤酒花中分离到的黄酮类化合物,可抑制 COX-1 和 COX-2 活性,具有抗肿瘤,抗血管生成的作用,还具有抗多种病毒的活性。 | |||
T1591 |
Ancitabine hydrochloride
NSC 145668 HCl,盐酸环胞苷,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C |
Others; DNA/RNA Synthesis; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
Ancitabine hydrochloride (NSC 145668 HCl) 是一种天然的抗白血病药物。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01201 |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His)
Human cytωlovirus (HCMV) Glycoprotein B/gB |
CMV | HEK293 Cells |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 93.2 kDa and the accession number is P13201. | |||
TMPY-00811 |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein
Human cytωlovirus (HCMV) Glycoprotein B/gB |
CMV | HEK293 Cells |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 92 kDa and the accession number is P13201. | |||
TMPY-00812 |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (aa 1-700, hFc)
Human cytωlovirus (HCMV) Glycoprotein B/gB |
CMV | HEK293 Cells |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (aa 1-700, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 104 kDa and the accession number is P13201. | |||
TMPY-00810 |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (hFc)
Human cytωlovirus (HCMV) Glycoprotein B/gB |
CMV | HEK293 Cells |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 118 kDa and the accession number is P13201. | |||
TMPH-01191 |
Human cytomegalovirus (HCMV) (strain Towne) glycoprotein UL132 Protein (Avi & His & MBP), Biotinylated
UL132,Envelope glycoprotein UL132 |
HHV-5 | E. coli |
Human cytomegalovirus (HCMV) (strain Towne) glycoprotein UL132 Protein (Avi & His & MBP), Biotinylated is expressed in E. coli. | |||
TMPH-01193 |
Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His)
Uncharacterized protein UL128,UL128 |
HHV-5 | E. coli |
Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His) is expressed in E. coli. | |||
TMPY-00054 |
Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc)
Macaca fascicularis Cytωlovirus (CyCMV) (strain OT-... |
CyCMV | HEK293 Cells |
Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 102.5 kDa and the accession number is E7DB34. | |||
TMPH-02412 |
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc)
Pre-glycoprotein polyprotein GP complex,GPC |
LCMV | E. coli |
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.9 kDa and the accession number is P07399. | |||
TMPH-01192 |
Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated
Phosphoprotein UL32,150 kDa matrix phosphoprotein,Tegument p... |
HHV-5 | E. coli |
Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated is expressed in E. coli. | |||
TMPH-01195 |
Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog
UL111A,Viral interleukin-10 homolog |
HCMV | E. coli |
Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog ... | |||
TMPH-01190 |
Human cytomegalovirus (HCMV) (strain AD169) glycoprotein H/gH Protein (His & SUMO)
gH,Envelope glycoprotein H |
HHV-5 | E. coli |
Human cytomegalovirus (HCMV) (strain AD169) glycoprotein H/gH Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.8 kDa and the accession number is P12824. | |||
TMPH-01194 |
Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO)
UL130,Uncharacterized protein UL130 |
HHV-5 | E. coli |
Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.... | |||
TMPH-02413 |
Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO)
GPC,Pre-glycoprotein polyprotein GP complex |
LCMV | E. coli |
Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.4 kDa and the accession number is P09991. | |||
TMPH-03406 |
Rhesus cytomegalovirus (RhCMV) (strain 68-1) Glycoprotein B/gB Protein (His & Myc)
gB,Envelope glycoprotein B |
RhCMV | E. coli |
Rhesus cytomegalovirus (RhCMV) (strain 68-1) Glycoprotein B/gB Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.0 kDa and the accession number is P89053. | |||
TMPJ-00131 |
NKG2DL Protein, Human, Recombinant (hFc)
ALCAN-β,NKG2DL1,UL16-binding protein 1,NKG2D ligand 1,ULBP1,... |
Human | HEK293 Cells |
NKG2D ligand 1, also called ULBP1, is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC molecules possess α1, α2 and α3 domains, ULBP/RAET1 family members lack α3 domain. ULBP1 is recognized by the activating receptor NKG2D on the surface of cytotoxic natural killer (NK) and T cells, and then promotes the lysis of cells expressing ULBP1 which is important for the im... | |||
TMPY-00575 |
ULBP-6 Protein, Human, Recombinant (His)
RAET1L,retinoic acid early transcript 1L,ULBP6 |
Human | HEK293 Cells |
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cel... | |||
TMPY-00190 |
ULBP-6 Protein, Human, Recombinant (hFc)
retinoic acid early transcript 1L,RAET1L,ULBP6 |
Human | HEK293 Cells |
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cel... | |||
TMPJ-01212 |
ULBP-1 Protein, Mouse, Recombinant (His)
RAET1I,ULBP1,NKG2DL1 |
Mouse | HEK293 Cells |
Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or inte... | |||
TMPY-02210 |
Serpin B9 Protein, Human, Recombinant (His)
CAP-3,PI-9,CAP3,PI9,serpin peptidase inhibitor, clade B (ova... |
Human | Baculovirus Insect Cells |
SerpinB9, also known as Cytoplasmic antiproteinase 3, CAP-3, Peptidase inhibitor 9, SERPINB9 and PI-9, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. Serpin-B9 ( CAP-3 / PI-9 ) is the only known human intracellular inhibitor of granzyme B (GrB), the effector molecule in immunity against cytomegalovirus (CMV) and in renal allograft rejection. Serpin-B9 and SPI-6 expression in immune-privileged cells, APCs, and CTLs protect these cells against the actions of gran... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TMIH-0298 |
Letermovir-d8
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Letermovir-d8 是 Letermovir 的氘代化合物。Letermovir 的 CAS 号为 917389-32-3。Letermovir是一种新型抗 CMV 抑制剂,靶向病毒末端酶,抑制其活性。 | |||
TMIJ-0306 |
Ganciclovir-d5
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Ganciclovir-d5 是 Ganciclovir 的氘代化合物。Ganciclovir 的 CAS 号为 82410-32-0。Ganciclovir是核苷类似物和口服抗病毒药物,对CMV具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。 |