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Search Results for " cma "
Targets Recommended: ADC Antibody

10

抑制剂 & 化合物

1

天然产物

26

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9901A-003 Gemtuzumab

CDP-771,CMA-676

ADC Antibody Antibody-drug Conjugate/ADC Related
Gemtuzumab(CMA-676) 是一种针对 CD33 抗原且由重组人源化 IgG4 抗体组成的单克隆抗体。Gemtuzumab 可用于合成一种抗体偶联化合物 (ADC)--Gemtuzumab ozogamicin 。Gemtuzumab 可用于研究急性髓性白血病。
T5317 Cridanimod

CMA,吖啶酮乙酸,XBIO-101,10-carboxymethyl-9-acridanone

Progesterone Receptor; STING; IFNAR Immunology/Inflammation; Others
Cridanimod (10-carboxymethyl-9-acridanone, CMA) 是一种是小分子免疫调节剂和干扰素诱导剂,是一种孕酮受体激活剂,能够诱导 IFNα和IFNβ的表达,显著增加 PR 的表达。
T9062 CA77.1

Autophagy Autophagy
CA77.1 是一种新型伴侣介导的自噬激活剂,用于治疗阿尔茨海默病。它是 AR7 的衍生物,可以增加溶酶体受体在溶酶体中的表达。
T4663 QX77

Others; Autophagy Autophagy; Others
QX77 是一种分子伴侣介导的自噬激活剂,可上调 LAMP2A 的表达。它可抑制 ES 细胞的自我更新,促进分化。它诱导 Rab11 上调,挽救 Rab11 下调和转运缺陷。
T3955 AR7

Retinoid Receptor Metabolism
AR7 是一种非典型的 RARA/RARα(视黄酸受体 α) 拮抗剂,能够特异性激活伴侣介导的自噬活性,对自噬无影响。
TP1806L BCMA72-80 acetate(2293841-58-2 free base)

Others Others
BCMA72-80 acetate(2293841-58-2 free base) 是一种 HLA-A2 特异性 B 细胞成熟抗原 (BCMA) 肽。它用于研究表达 B 细胞成熟抗原的多发性骨髓瘤和肿瘤。
T41277 PACMA 31

Others Others
PACMA 31 是一种不可逆的共价蛋白二硫键异构酶 (PDI) 抑制剂,IC50 为 10 μM。 PACMA 31 显着抑制卵巢肿瘤生长并表现出肿瘤靶向能力。
T82461 Epacmarstobart

GS-0189,FSI-189

Epacmarstobart(FSI-189; GS-0189)为针对小鼠SIRPA(信号调节蛋白α)的嵌合人源化IgG1κ单克隆抗体。
TP1806 BCMA72-80

BCMA72-80 is a HLA-A2-specific B-cell maturation antigen (BCMA) peptide, with a strong affinity to HLA-A2. It is used to used in the research of multiple myeloma or other B-cell maturation antigen expressing tumors.
T78371 Ac2-26 ammonium

Ac2-26 ammonium是一种具抗炎作用的annexin 1 N末端肽。该化合物能够通过伴侣介导的自噬(CMA)机制降低溶酶体中的IKKβ蛋白含量,从而改善肺缺血再灌注损伤,并在哮喘大鼠模型中抑制气道炎症以及高反应性的表现。

化合物

Gemtuzumab
Cat.No: T9901A-003
Synonym: CDP-771,CMA-676
Target: ADC Antibody
Cridanimod
Cat.No: T5317
Synonym: CMA,吖啶酮乙酸,XBIO-101,10-carboxymethyl-9-acridanone
Target: Progesterone Receptor, STING, IFNAR
CA77.1
Cat.No: T9062
Synonym:
Target: Autophagy
QX77
Cat.No: T4663
Synonym:
Target: Others, Autophagy
AR7
Cat.No: T3955
Synonym:
Target: Retinoid Receptor
BCMA72-80 acetate(2293841-58-2 free base)
Cat.No: TP1806L
Synonym:
Target: Others
PACMA 31
Cat.No: T41277
Synonym:
Target: Others
Epacmarstobart
Cat.No: T82461
Synonym: GS-0189,FSI-189
Target:
BCMA72-80
Cat.No: TP1806
Synonym:
Target:
Ac2-26 ammonium
Cat.No: T78371
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN3972 Epimedokoreanin B

Apoptosis; Others; Antibacterial Apoptosis; Microbiology/Virology; Others
Epimedokoreanin B (EKB) 是一种从韩国淫羊藿中分离出的异戊烯化类黄酮,在人非小细胞肺癌(NSCLC)A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性,可有清除 DPPH 自由基的活性,能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -(羧甲基)赖氨酸(CML)和 N (Ï) -(羧甲基)精氨酸(CMA)的形成,可通过抑制高级糖化终产物(AGEs)预防糖尿病的临床并发症。

天然产物

Epimedokoreanin B
Cat.No: TN3972
Synonym:
Target: Apoptosis, Others, Antibacterial
Cat. No. Product Name Species Expression System
TMPY-03213 BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)

tumor necrosis factor receptor superfamily member 17

Rhesus HEK293 Cells
BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33 kDa and the accession number is A0A2K5UD97.
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His)

BCMA,TNFRSF13A,CD269,tumor necrosis factor receptor...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 7.3 kDa and the accession number is Q02223-1.
TMPY-05568 BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated

BCMA,TNFRSF13A,tumor necrosis factor receptor super...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated is expressed in HEK293 mammalian cells with His and Fc tag. The accession number is NP_001183.2.
TMPY-04493 BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)

tumor necrosis factor receptor superfamily member 17,BCM...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 33.3 kDa and the accession number is Q02223-1.
TMPY-05385 BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)

CD269,BCM,tumor necrosis factor receptor superfamily member ...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 32.6 kDa and the accession number is Q02223-1.
TMPY-02913 BCMA/TNFRSF17 Protein, Rat, Recombinant (hFc)

tumor necrosis factor receptor superfamily member 17

Rat HEK293 Cells
BCMA/TNFRSF17 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34 kDa and the accession number is D3ZKQ8.
TMPJ-00066 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)

Tumor necrosis factor receptor superfamily member 17,Tnfrsf1...

Human HEK293 Cells
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane domain, and a 113 aa intracellular domain. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand ...
TMPK-00065 BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi)

BCM,TNFRSF13A,TNFRSF17,CD269,BCMA

Human HEK293 Cells
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.5 kDa and the accession number is Q02223.
TMPJ-01245 UCMA Protein, Human, Recombinant

UCMA,Unique cartilage matrix-associated protein,Gla...

Human E. coli
C10orf49 is a secreted protein which encoded by the UCMA gene. It is a member of the UCMA family. C10orf49 is predominantly expressed in resting chondrocytes. It may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
TMPH-01525 CMAHP Protein, Human, Recombinant (His & Myc)

CMAHP,Inactive cytidine monophosphate-N-acetylneura...

Human E. coli
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates. However, it may play a role in Wnt signaling.
TMPY-05595 BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

tumor necrosis factor receptor superfamily member 17,BCM...

Mouse HEK293 Cells
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 34 kDa and the accession number is O88472-1.
TMPY-00966 BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc)

Tnfrsf13a,BCMA,tumor necrosis factor receptor super...

Mouse HEK293 Cells
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession number is O88472-1.
TMPK-00069 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), Biotinylated

BCMA,BCM,CD269,TNFRSF17,TNFRSF13A

Human HEK293 Cells
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.9 kDa and the accession number is Q0222...
TMPK-00068 BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi), Biotinylated

CD269,TNFRSF17,BCMA,TNFRSF13A,BCM

Human HEK293 Cells
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.5 kDa and the accession number ...
TMPK-00066 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), FITC-Labeled

CD269,TNFRSF17,TNFRSF13A,BCMA,BCM

Human HEK293 Cells
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.9 kDa and the accession number is Q0222...
TMPK-00064 BCMA/TNFRSF17 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

TNFRSF13A,BCMA,TNFRSF17,BCM,CD269

Cynomolgus,Rhesus HEK293 Cells
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 7.10 kDa and the accession number is A0A2K5UD...
TMPY-05197 BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)

BCMA,TNFRSF13A,tumor necrosis factor receptor super...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 32.3 kDa and the accession number is Q02223-1.
TMPY-01211 BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc)

BCMA,tumor necrosis factor receptor superfamily mem...

Mouse HEK293 Cells
BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 33.7 kDa and the accession number is O88472-1.
TMPK-00071 BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi)

TNFRSF17,BCMA,BCM,TNFRSF13A,CD269

Mouse HEK293 Cells
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.5 kDa and the accession number is O88472-1.
TMPJ-01446 BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)

B-cell maturation protein,CD269,Bcma,Tnfrsf17,Bcm,T...

Cynomolgus HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 12 and 15-20 KDa and the accession number is G7Q0I4.
TMPY-05136 BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated

tumor necrosis factor receptor superfamily member 17

Rhesus HEK293 Cells
BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.5 kDa and the accession number is A0A2K5UD97.
TMPY-05328 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)

CD269,TNFRSF13A,BCM,BCMA,tumor necrosis factor rece...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 10 kDa and the accession number is Q02223-1.
TMPJ-01434 BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)

Bcma,Tnfrsf17,B-cell maturation protein,Bcm,CD269,T...

Cynomolgus HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 38-45 KDa and the accession number is G7Q0I4.
TMPK-00072 BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TNFRSF13A,TNFRSF17,BCM,BCMA,CD269

Mouse HEK293 Cells
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.5 kDa and the accession number is O8847...
TMPY-06757 BCMA/TNFRSF17 Protein, Human, Recombinant (hFc & Avi), Biotinylated

CD269,TNFRSF13A,BCMA,tumor necrosis factor receptor...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 27.80 kDa and the accession number is NP_001183.2.
TMPY-05567 BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated

tumor necrosis factor receptor superfamily member 17,BCM...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated is expressed in HEK293 mammalian cells with His and Fc tag. The accession number is NP_001183.2.

重组蛋白

BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03213
Species: Rhesus
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
Cat.No: TMPY-05319
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
Cat.No: TMPY-05568
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)
Cat.No: TMPY-04493
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05385
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-02913
Species: Rat
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00066
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00065
Species: Human
Expression System: HEK293 Cells
UCMA Protein, Human, Recombinant
Cat.No: TMPJ-01245
Species: Human
Expression System: E. coli
CMAHP Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01525
Species: Human
Expression System: E. coli
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05595
Species: Mouse
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00966
Species: Mouse
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00069
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00068
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00066
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00064
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05197
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-01211
Species: Mouse
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi)
Cat.No: TMPK-00071
Species: Mouse
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01446
Species: Cynomolgus
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated
Cat.No: TMPY-05136
Species: Rhesus
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPY-05328
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01434
Species: Cynomolgus
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00072
Species: Mouse
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06757
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated
Cat.No: TMPY-05567
Species: Human
Expression System: HEK293 Cells
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