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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
TMAZ-0066P	Anti-CHIT1 Monoclonal Antibody-PE

TMAZ-0066B	Anti-CHIT1 Monoclonal Antibody-Biotin

TMAZ-0066A	Anti-CHIT1 Monoclonal Antibody-APC

T9592	OATD-01	Others	Others
	OATD-01 是一种壳三糖苷酶及酸性哺乳动物几丁质酶的高活性抑制剂，对CHIT1具有低纳摩尔活性 (hCHIT1,IC50=23 nM)。它在多个物种中显示出良好的药代动力学特征，在体内具有显著的抗纤维化活性，可用于研究肺纤维化。
TMAZ-0066A6	Anti-CHIT1 Monoclonal Antibody-AF647

TMAZ-0066A4	Anti-CHIT1 Monoclonal Antibody-AF488

TMAZ-0066A5	Anti-CHIT1 Monoclonal Antibody-AF555

T9952	OAT-2068	Others	Others
	OAT-2068 是一种有效且选择性的小鼠壳三糖苷酶 (CHIT1) 抑制剂，与 mAMCase 相比，mCHIT1 的选择性高出 143 倍。

化合物

Anti-CHIT1 Monoclonal Antibody-PE

Cat.No: TMAZ-0066P

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Anti-CHIT1 Monoclonal Antibody-Biotin

Cat.No: TMAZ-0066B

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Anti-CHIT1 Monoclonal Antibody-APC

Cat.No: TMAZ-0066A

Anti-CHIT1 Monoclonal Antibody-AF647

Cat.No: TMAZ-0066A6

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Anti-CHIT1 Monoclonal Antibody-AF488

Cat.No: TMAZ-0066A4

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Anti-CHIT1 Monoclonal Antibody-AF555

Cat.No: TMAZ-0066A5

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Cat. No.	Product Name	Species	Expression System
TMPY-01290	CHIT1 Protein, Human, Recombinant (His) chitinase 1 (chitotriosidase),	Human	HEK293 Cells
	Chitotriosidase, also known as Chitinase-1 and CHIT1, is a member of the glycosyl hydrolase 18 family and Chitinase class II subfamily. It is a member of the mammalian chitinase family, structurally homologous to chitinases from other species, is synthesized and secreted by specifically activated macrophages. Chitotriosidase is a polymer of N-acetylglucosamine. Serum and plasma chitotriosidase activity is usually measured as the first step in diagnosis of Gaucher disease. Monitoring chitotriosid...
TMPK-01127	AMCase/CHIA Protein, Mouse, Recombinant (His) CHIT2,Chia1,AMCase,YNL,Acidic mammalian	Mouse	HEK293 Cells
	Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. The expression of AMCase and CHIT-1 were differently modulated in HMMs at different stage of maturation.
TMPK-01154	AMCase/CHIA Protein, Human, Recombinant (His) YNL,AMCase,Chia1,CHIA,Acidic mammalian chit	Human	HEK293 Cells
	Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages'...