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Search Results for " cdki-83 "
Targets Recommended: Others

2

抑制剂 & 化合物

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T71287 CDKI-83

Others Others
CDKI-83 is a potent CDK9 inhibitor. The compound shows effective anti-proliferative activity in human tumour cell lines with GI50 <1 μM, and is capable of inducing apoptosis in A2780 human ovarian cancer cells as determined by the activated caspase-3, Annexin V/PI double staining and accumulated cells at the sub-G1 phase of cellcycle. The research results suggest that combined inhibition of CDK9 and CDK1 may result in the effective induction of apoptosis and CDKI-83 has the potential to be devel...
T1610 Metaxalone

Skelaxin,Methaxalonum,美他沙酮,Zorane,NSC170959,AHR438

Others Others
Metaxalone (Methaxalonum) 具有肌肉松弛作用。

化合物

CDKI-83
Cat.No: T71287
Synonym:
Target: Others
Metaxalone
Cat.No: T1610
Synonym: Skelaxin,Methaxalonum,美他沙酮,Zorane,NSC170959,AHR438
Target: Others
Cat. No. Product Name Target Signaling Pathways
T71285 Metaxalone-d6

Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone ...

同位素标记化合物

Metaxalone-d6
Cat.No: T71285
Synonym:
Target:
TargetMol Loading
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