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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82764 |
Cd1a
β-TRTX-cd1a,β-Theraphotoxin-cd1a |
Others | Others |
Cd1a是从非洲蜘蛛Ceratogyrus darlingi中提取的β-毒素,具有调节钙离子通道的功能。它能够抑制人类的钙离子通道(Cav2.2)(IC50 2.6 μM)以及小鼠的钠离子通道(Nav1.7),有望用于开发治疗外周疼痛的药物。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04739 |
CD1A & B2M Heterodimer Protein, Rhesus, Recombinant (His)
CD1A & B2M |
Rhesus | HEK293 Cells |
CD1A & B2M Heterodimer Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.2 kDa and the accession number is NP_001139290.1&NP_001040602.1. | |||
TMPK-00694 |
CD1A Protein, Human, Recombinant (His)
CD1,HTA1,FCB6,T6,R4,CD1a |
Human | HEK293 Cells |
CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tails (CTs) of all human CD1 isoforms, with the exception of CD1a, contain tyrosine-based sorting motifs, responsible for the internalization of proteins by the clathrin-mediated pathway. CD1a closer to MHC class I in its trafficking and potential antigen-loading compartments among CD1 isoforms. | |||
TMPY-02885 |
CD1B Protein, Human, Recombinant (hFc)
CD1,CD1A,CD1b molecule,R... |
Human | HEK293 Cells |
CD1B contains 1 Ig-like (immunoglobulin-like) domain and belongs to the CD1 family. CD1 family members are transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. During protein synthesis and maturation, they bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface. CD... | |||
TMPY-04117 |
CD1D Protein, Mouse, Recombinant (His & hFc)
CD1.1,Cd1a,Cd1d,CD |
Mouse | HEK293 Cells |
CD1D Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 60.4 kDa and the accession number is A0A0R4J090. | |||
TMPY-01397 |
CD1D Protein, Mouse, Recombinant (His)
Cd1d,Cd1a,CD1d molecule,... |
Mouse | HEK293 Cells |
CD1D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.7 kDa and the accession number is A0A0R4J090. |