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Search Results for " cd10 "
Targets Recommended: Neprilysin

12

抑制剂 & 化合物

1

天然产物

18

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T7693 Thiorphan

Neprilysin Metabolism
Thiorphan 是选择性neprilysin 抑制剂 (IC50:6.9 nM) 。
T1176 Racecadotril

Acetorphan,消旋卡多曲

Neprilysin; Proteasome Metabolism; Proteases/Proteasome; Ubiquitination
Racecadotril (Acetorphan) 是一种中性内肽酶 (NEP) 抑制剂,具有止泻作用。Racecadotril 及其活性代谢物 Thiorphan 抑制小鼠脑中纯化的NEP 活性,Ki 分别为 4500 和 6.1 nM。
TQ0106 Sacubitrilat

LBQ-657

Neprilysin Metabolism
Sacubitrilat (LBQ-657) 是活性的脑啡肽酶 (NEP) 抑制剂。
T4574 Sacubitril

AHU 377,AHU377,沙库必曲,AHU-377

Neprilysin Metabolism
Sacubitril (AHU-377) 是一种有效的NEP 抑制剂,IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。
T4200 Sacubitril hemicalcium salt

AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt

Neprilysin Metabolism
Sacubitril hemicalcium salt (AHU377 calcium salt) 是一种有效的 NEP 抑制剂,IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。
T2318 Sacubitril/Valsartan

Sacubitril mixture with Valsartan,沙库必曲/缬沙坦,Valsartan,Sacubitril,LCZ696

Apoptosis; RAAS; Neprilysin Apoptosis; Endocrinology/Hormones; Metabolism
Sacubitril/Valsartan (LCZ696),以1:1摩尔比由Valsartan(一种ARB)和Sacubitril(AHU377)组成,为创新口服血管紧张素受体-脑啡肽酶(ARN)双重抑制剂,旨在治疗高血压与心力衰竭。其作用机制包括抑制炎症、氧化应激及细胞凋亡,有助于改善糖尿病心肌病。
TMAZ-0002P Anti-CD109 Monoclonal Antibody-PE

TMAZ-0002A4 Anti-CD109 Monoclonal Antibody-AF488

TMAZ-0002A6 Anti-CD109 Monoclonal Antibody-AF647

TMAZ-0002A Anti-CD109 Monoclonal Antibody-APC

TMAZ-0002B Anti-CD109 Monoclonal Antibody-Biotin

TMAZ-0002A5 Anti-CD109 Monoclonal Antibody-AF555

化合物

Thiorphan
Cat.No: T7693
Synonym:
Target: Neprilysin
Racecadotril
Cat.No: T1176
Synonym: Acetorphan,消旋卡多曲
Target: Neprilysin, Proteasome
Sacubitrilat
Cat.No: TQ0106
Synonym: LBQ-657
Target: Neprilysin
Sacubitril
Cat.No: T4574
Synonym: AHU 377,AHU377,沙库必曲,AHU-377
Target: Neprilysin
Sacubitril hemicalcium salt
Cat.No: T4200
Synonym: AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt
Target: Neprilysin
Sacubitril/Valsartan
Cat.No: T2318
Synonym: Sacubitril mixture with Valsartan,沙库必曲/缬沙坦,Valsartan,Sacubitril,LCZ696
Target: Apoptosis, RAAS, Neprilysin
Anti-CD109 Monoclonal Antibody-PE
Cat.No: TMAZ-0002P
Synonym:
Target:
Anti-CD109 Monoclonal Antibody-AF488
Cat.No: TMAZ-0002A4
Synonym:
Target:
Anti-CD109 Monoclonal Antibody-AF647
Cat.No: TMAZ-0002A6
Synonym:
Target:
Anti-CD109 Monoclonal Antibody-APC
Cat.No: TMAZ-0002A
Synonym:
Target:
Anti-CD109 Monoclonal Antibody-Biotin
Cat.No: TMAZ-0002B
Synonym:
Target:
Anti-CD109 Monoclonal Antibody-AF555
Cat.No: TMAZ-0002A5
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T6627 Phosphoramidon Disodium

Phosphoramidon Disodium Salt,磷酰胺二钠

RAAS; Neprilysin; Others Endocrinology/Hormones; Metabolism; Others
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂 。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ,中性肽内切酶 (NEP) 和血管紧张素转换酶 (ACE) 的IC50分别为 3.5 ,0.034 和 78 μM。

天然产物

Phosphoramidon Disodium
Cat.No: T6627
Synonym: Phosphoramidon Disodium Salt,磷酰胺二钠
Target: RAAS, Neprilysin, Others
Cat. No. Product Name Species Expression System
TMPY-00760 CD10 Protein, Human, Recombinant

membrane metallo-endopeptidase,CALLA,CD10,...

Human HEK293 Cells
CD10 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 80 kDa and the accession number is P08473.
TMPY-00759 CD10 Protein, Human, Recombinant (hFc)

NEP,SFE,membrane metallo-endopeptidase,CD10

Human HEK293 Cells
CD10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 106 kDa and the accession number is P08473.
TMPY-02315 CD10 Protein, Human, Recombinant (His)

membrane metallo-endopeptidase,SFE,CALLA,NEP,CD...

Human HEK293 Cells
CD10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.2 kDa and the accession number is P08473.
TMPY-01093 CD10 Protein, Mouse, Recombinant (His)

CALLA,SFE,CD10,C85356,6030454K05Rik,NEP,me...

Mouse HEK293 Cells
CD10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.2 kDa and the accession number is Q61391.
TMPY-02762 CD10 Protein, Rhesus, Recombinant (His)

membrane metallo-endopeptidase

Rhesus HEK293 Cells
CD10 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.1 kDa and the accession number is A0A8J8Y120.
TMPY-03539 CD10 Protein, Rat, Recombinant (His)

membrane metallo-endopeptidase

Rat HEK293 Cells
CD10 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P07861.
TMPY-01384 Endoglin/CD105 Protein, Human, Recombinant (His)

endoglin,HHT1,END,ORW1

Human HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.3 kDa and the accession number is A0A024R878.
TMPH-01913 PDCD10 Protein, Human, Recombinant (His & SUMO)

PDCD10,Cerebral cavernous malformations 3 ...

Human E. coli
PDCD10 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-01418 ICAM-2/CD102 Protein, Human, Recombinant (His)

CD102,intercellular adhesion molecule 2

Human HEK293 Cells
ICAM-2/CD102 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P13598.
TMPJ-01300 PDCD10 Protein, Human, Recombinant

TFAR15,Programmed Cell Death Protein 10,PDCD

Human E. coli
Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is required for normal cardiovascular development and normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Defects in PDCD10 are the cause of cerebral cavernous malformations type 3.
TMPY-01799 ICAM-2/CD102 Protein, Mouse, Recombinant (hFc)

intercellular adhesion molecule 2,Ly-60,CD10

Mouse HEK293 Cells
ICAM-2/CD102 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50 kDa and the accession number is P35330.
TMPY-03533 ICAM-2/CD102 Protein, Mouse, Recombinant

Icam-2,intercellular adhesion molecule 2,Ly-60,CD

Mouse HEK293 Cells
ICAM-2/CD102 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23.6 kDa and the accession number is P35330.
TMPK-00359 Endoglin/CD105 Protein, Human, Recombinant (His & Avi)

CD105,ORW,ORW1,ENG,END,Endoglin,HHT1

Human HEK293 Cells
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response...
TMPY-00826 ICAM-2/CD102 Protein, Human, Recombinant (His & hFc)

CD102,intercellular adhesion molecule 2

Human HEK293 Cells
ICAM-2/CD102 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 50.3 kDa and the accession number is P13598.
TMPY-00783 Endoglin/CD105 Protein, Human, Recombinant (hFc)

END,HHT1,ORW1,endoglin

Human HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.5 kDa and the accession number is A0A024R878.
TMPH-02722 CD101 Protein, Mouse, Recombinant (His)

Glu-Trp-Ile EWI motif-containing protein 101,Immuno...

Mouse Baculovirus Insect Cells
CD101 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 29.6 kDa and the accession number is A8E0Y8.
TMPY-01615 Endoglin/CD105 Protein, Mouse, Recombinant (His)

Endo,CD105,S-endoglin,AI528660,endoglin,AI...

Mouse HEK293 Cells
Endoglin/CD105 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.2 kDa and the accession number is Q63961.
TMPY-02810 Ninjurin-1 Protein, Rat, Recombinant (hFc)

ninjurin 1

Rat HEK293 Cells
Ninjurin-1, also known as NINJ1, is a member of the Ninjurin family of transmembrane (TM) proteins. It is expressed in CD19(+) CD10(+) B-cell progenitor cells and higher levels in B-lineage acute lymphoblastic leukemia cells. Ninjurin-1 is expressed also in some other adult and embryonic tissues, predominantly in epithelial cells. Its expression is upregulated after axotomy in neurons and Schwann cells surrounding the distal nerve segment. Upregulated expression of ninjurin-1 has been identified...

重组蛋白

CD10 Protein, Human, Recombinant
Cat.No: TMPY-00760
Species: Human
Expression System: HEK293 Cells
CD10 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00759
Species: Human
Expression System: HEK293 Cells
CD10 Protein, Human, Recombinant (His)
Cat.No: TMPY-02315
Species: Human
Expression System: HEK293 Cells
CD10 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01093
Species: Mouse
Expression System: HEK293 Cells
CD10 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-02762
Species: Rhesus
Expression System: HEK293 Cells
CD10 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03539
Species: Rat
Expression System: HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (His)
Cat.No: TMPY-01384
Species: Human
Expression System: HEK293 Cells
PDCD10 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01913
Species: Human
Expression System: E. coli
ICAM-2/CD102 Protein, Human, Recombinant (His)
Cat.No: TMPY-01418
Species: Human
Expression System: HEK293 Cells
PDCD10 Protein, Human, Recombinant
Cat.No: TMPJ-01300
Species: Human
Expression System: E. coli
ICAM-2/CD102 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01799
Species: Mouse
Expression System: HEK293 Cells
ICAM-2/CD102 Protein, Mouse, Recombinant
Cat.No: TMPY-03533
Species: Mouse
Expression System: HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00359
Species: Human
Expression System: HEK293 Cells
ICAM-2/CD102 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00826
Species: Human
Expression System: HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00783
Species: Human
Expression System: HEK293 Cells
CD101 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02722
Species: Mouse
Expression System: Baculovirus Insect Cells
Endoglin/CD105 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01615
Species: Mouse
Expression System: HEK293 Cells
Ninjurin-1 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-02810
Species: Rat
Expression System: HEK293 Cells
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