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18
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7693 |
Thiorphan
|
Neprilysin | Metabolism |
Thiorphan 是选择性neprilysin 抑制剂 (IC50:6.9 nM) 。 | |||
T1176 |
Racecadotril
Acetorphan,消旋卡多曲 |
Neprilysin; Proteasome | Metabolism; Proteases/Proteasome; Ubiquitination |
Racecadotril (Acetorphan) 是一种中性内肽酶 (NEP) 抑制剂,具有止泻作用。Racecadotril 及其活性代谢物 Thiorphan 抑制小鼠脑中纯化的NEP 活性,Ki 分别为 4500 和 6.1 nM。 | |||
TQ0106 |
Sacubitrilat
LBQ-657 |
Neprilysin | Metabolism |
Sacubitrilat (LBQ-657) 是活性的脑啡肽酶 (NEP) 抑制剂。 | |||
T4574 |
Sacubitril
AHU 377,AHU377,沙库必曲,AHU-377 |
Neprilysin | Metabolism |
Sacubitril (AHU-377) 是一种有效的NEP 抑制剂,IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。 | |||
T4200 |
Sacubitril hemicalcium salt
AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt |
Neprilysin | Metabolism |
Sacubitril hemicalcium salt (AHU377 calcium salt) 是一种有效的 NEP 抑制剂,IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。 | |||
T2318 |
Sacubitril/Valsartan
Sacubitril mixture with Valsartan,沙库必曲/缬沙坦,Valsartan,Sacubitril,LCZ696 |
Apoptosis; RAAS; Neprilysin | Apoptosis; Endocrinology/Hormones; Metabolism |
Sacubitril/Valsartan (LCZ696),以1:1摩尔比由Valsartan(一种ARB)和Sacubitril(AHU377)组成,为创新口服血管紧张素受体-脑啡肽酶(ARN)双重抑制剂,旨在治疗高血压与心力衰竭。其作用机制包括抑制炎症、氧化应激及细胞凋亡,有助于改善糖尿病心肌病。 | |||
TMAZ-0002P |
Anti-CD109 Monoclonal Antibody-PE
|
||
TMAZ-0002A4 |
Anti-CD109 Monoclonal Antibody-AF488
|
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TMAZ-0002A6 |
Anti-CD109 Monoclonal Antibody-AF647
|
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TMAZ-0002A |
Anti-CD109 Monoclonal Antibody-APC
|
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TMAZ-0002B |
Anti-CD109 Monoclonal Antibody-Biotin
|
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TMAZ-0002A5 |
Anti-CD109 Monoclonal Antibody-AF555
|
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6627 |
Phosphoramidon Disodium
Phosphoramidon Disodium Salt,磷酰胺二钠 |
RAAS; Neprilysin; Others | Endocrinology/Hormones; Metabolism; Others |
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂 。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ,中性肽内切酶 (NEP) 和血管紧张素转换酶 (ACE) 的IC50分别为 3.5 ,0.034 和 78 μM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00760 |
CD10 Protein, Human, Recombinant
membrane metallo-endopeptidase,CALLA,CD10,... |
Human | HEK293 Cells |
CD10 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 80 kDa and the accession number is P08473. | |||
TMPY-00759 |
CD10 Protein, Human, Recombinant (hFc)
NEP,SFE,membrane metallo-endopeptidase,CD10 |
Human | HEK293 Cells |
CD10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 106 kDa and the accession number is P08473. | |||
TMPY-02315 |
CD10 Protein, Human, Recombinant (His)
membrane metallo-endopeptidase,SFE,CALLA,NEP,CD... |
Human | HEK293 Cells |
CD10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.2 kDa and the accession number is P08473. | |||
TMPY-01093 |
CD10 Protein, Mouse, Recombinant (His)
CALLA,SFE,CD10,C85356,6030454K05Rik,NEP,me... |
Mouse | HEK293 Cells |
CD10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.2 kDa and the accession number is Q61391. | |||
TMPY-02762 |
CD10 Protein, Rhesus, Recombinant (His)
membrane metallo-endopeptidase |
Rhesus | HEK293 Cells |
CD10 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.1 kDa and the accession number is A0A8J8Y120. | |||
TMPY-03539 |
CD10 Protein, Rat, Recombinant (His)
membrane metallo-endopeptidase |
Rat | HEK293 Cells |
CD10 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P07861. | |||
TMPY-01384 |
Endoglin/CD105 Protein, Human, Recombinant (His)
endoglin,HHT1,END,ORW1 |
Human | HEK293 Cells |
Endoglin/CD105 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.3 kDa and the accession number is A0A024R878. | |||
TMPH-01913 |
PDCD10 Protein, Human, Recombinant (His & SUMO)
PDCD10,Cerebral cavernous malformations 3 ... |
Human | E. coli |
PDCD10 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-01418 |
ICAM-2/CD102 Protein, Human, Recombinant (His)
CD102,intercellular adhesion molecule 2 |
Human | HEK293 Cells |
ICAM-2/CD102 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P13598. | |||
TMPJ-01300 |
PDCD10 Protein, Human, Recombinant
TFAR15,Programmed Cell Death Protein 10,PDCD |
Human | E. coli |
Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is required for normal cardiovascular development and normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Defects in PDCD10 are the cause of cerebral cavernous malformations type 3. | |||
TMPY-01799 |
ICAM-2/CD102 Protein, Mouse, Recombinant (hFc)
intercellular adhesion molecule 2,Ly-60,CD10 |
Mouse | HEK293 Cells |
ICAM-2/CD102 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50 kDa and the accession number is P35330. | |||
TMPY-03533 |
ICAM-2/CD102 Protein, Mouse, Recombinant
Icam-2,intercellular adhesion molecule 2,Ly-60,CD |
Mouse | HEK293 Cells |
ICAM-2/CD102 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23.6 kDa and the accession number is P35330. | |||
TMPK-00359 |
Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
CD105,ORW,ORW1,ENG,END,Endoglin,HHT1 |
Human | HEK293 Cells |
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response... | |||
TMPY-00826 |
ICAM-2/CD102 Protein, Human, Recombinant (His & hFc)
CD102,intercellular adhesion molecule 2 |
Human | HEK293 Cells |
ICAM-2/CD102 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 50.3 kDa and the accession number is P13598. | |||
TMPY-00783 |
Endoglin/CD105 Protein, Human, Recombinant (hFc)
END,HHT1,ORW1,endoglin |
Human | HEK293 Cells |
Endoglin/CD105 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.5 kDa and the accession number is A0A024R878. | |||
TMPH-02722 |
CD101 Protein, Mouse, Recombinant (His)
Glu-Trp-Ile EWI motif-containing protein 101,Immuno... |
Mouse | Baculovirus Insect Cells |
CD101 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 29.6 kDa and the accession number is A8E0Y8. | |||
TMPY-01615 |
Endoglin/CD105 Protein, Mouse, Recombinant (His)
Endo,CD105,S-endoglin,AI528660,endoglin,AI... |
Mouse | HEK293 Cells |
Endoglin/CD105 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.2 kDa and the accession number is Q63961. | |||
TMPY-02810 |
Ninjurin-1 Protein, Rat, Recombinant (hFc)
ninjurin 1 |
Rat | HEK293 Cells |
Ninjurin-1, also known as NINJ1, is a member of the Ninjurin family of transmembrane (TM) proteins. It is expressed in CD19(+) CD10(+) B-cell progenitor cells and higher levels in B-lineage acute lymphoblastic leukemia cells. Ninjurin-1 is expressed also in some other adult and embryonic tissues, predominantly in epithelial cells. Its expression is upregulated after axotomy in neurons and Schwann cells surrounding the distal nerve segment. Upregulated expression of ninjurin-1 has been identified... |