Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00526 |
Langerin/CD207 Protein, Human, Recombinant (His)
C-type lectin domain family 4 member K,langerin,CD<... |
Human | HEK293 Cells |
Langerin (CD207) is a type II transmembrane glycoprotein which is member K of the C-type lectin domain family. Langerin is used as a marker for Langerhans cells (LCs) which represent the immature dendritic cells in the epidermis. Langerin is necessary and sufficient for Birbeck granule formation. Human langerin sequence contains a 43 aa cytoplasmic domain, a 21 aa transmembrane domain and a 264 aa extracellular domain (ECD) that contains a coiled-coil domain and a single C-type lectin domain. Hu... |