Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00526 |
Langerin/CD207 Protein, Human, Recombinant (His)
C-type lectin domain family 4 member K,langerin,CD<... |
Human | HEK293 Cells |
Langerin (CD207) is a type II transmembrane glycoprotein which is member K of the C-type lectin domain family. Langerin is used as a marker for Langerhans cells (LCs) which represent the immature dendritic cells in the epidermis. Langerin is necessary and sufficient for Birbeck granule formation. Human langerin sequence contains a 43 aa cytoplasmic domain, a 21 aa transmembrane domain and a 264 aa extracellular domain (ECD) that contains a coiled-coil domain and a single C-type lectin domain. Hu... | |||
TMPY-00063 |
Langerin/CD207 Protein, Rhesus, Recombinant (hFc)
CD207 molecule, langerin |
Rhesus | HEK293 Cells |
Langerin/CD207 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 58.3 kDa and the accession number is G7NAA3. | |||
TMPH-02611 |
Langerin/CD207 Protein, Mouse, Recombinant (His)
C-type lectin domain family 4 member K,Langerin,Cd<... |
Mouse | E. coli |
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. |