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Search Results for " cck 8 "
Targets Recommended: Others

11

抑制剂 & 化合物

1

TargetMol 试剂盒

10

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Cat. No. Product Name Form Specificity Of Inhibition
C0005 Cell Counting Kit-8 (CCK-8)

Cell Counting Kit-8 (CCK-8)

Solution in bottle

TargetMol 试剂盒

Cell Counting Kit-8 (CCK-8)
Cat.No: C0005
Cat. No. Product Name Target Signaling Pathways
TP1197 Sincalide

SQ19844,辛卡利特,CCK-8,Cholecystokinin octapeptide

Others Others
Sincalide (CCK-8) 是一种速效的胆囊收缩素的氨基酸多肽激素类似物,可在胆囊造影术中静脉使用。它的肝胆生理作用是增加胆汁的分泌,使胆囊收缩并使 Oddi 的括约肌松弛,从而使胆汁排入十二指肠。它是一种通过注射促进胆囊收缩并帮助诊断胆囊和胰腺疾病的药物。
TP1198 Sincalide ammonium

SQ19844 ammonium,CCK-8 ammonium,Cholecystokinin octapeptide ammonium

cholecystokinin GPCR/G Protein
Sincalide ammonium (CCK-8 ammonium) 是一种有效的氨基酸多肽激素胆囊收缩素 (CCK) 的类似物,是保留了 CCK 的大部分生物活性的活性片段。Sincalide ammonium 促进胆汁的分泌,使胆囊收缩并使 Oddi 的括约肌松弛,从而促进胆汁排入十二指肠。Sincalide ammonium 可通过注射促进胆囊收缩,常用于辅助诊断胆囊、胰腺疾病和胆囊造影术。
T9343 N-Cbz-DL-tryptophan

cholecystokinin GPCR/G Protein
N-Cbz-DL-tryptophan 是一种胆囊收缩素受体拮抗剂,可消除离体心脏对 CCK-8 的反应。
TP1931L1 [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)

cholecystokinin GPCR/G Protein
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) 是广谱神经肽反向激动剂和拮抗剂。 ghrelin 受体的强效完全反向激动剂(EC50 = 5.2 nM);减少组成型生长素释放肽受体信号传导。它也是速激肽、缓激肽、CCK 和铃蟾肽受体的拮抗剂。在体外诱导细胞凋亡并抑制癌细胞生长。
T34669 Snf 8906

Snf-8906,Snf8906

Others Others
Snf 8906 is a CCK-8 analog.
T25108 ARL 15849XX

ARL15849XX,FPL15849,FPL-15849,FPL 15849,ARL-15849XX

Others Others
ARL 15849XX, a CCK-8 analog, is a novel anti-obesity agent.
T25437 Fpl 14294

Fpl-14294,Fpl14294

Others Others
Fpl 14294 is a novel CCK-8 agonist with effective intranasal anorectic activity in the rat.
T16906 Sograzepide

YM-220,Netazepide,YF 476

Others Others
Sograzepide is an effective and highly selective Gastrin/CCK-B antagonist (IC50: 0.1 nM), has an inhibitory effect on Gastrin/CCK-A activity (IC50: 502 nM). Sograzepide replaces the specific binding of [125I]CCK-8 to the rat brain, cloned canine, and cloned human Gastrin/CCK-B receptors (Ki: 0.068, 0.62 and 0.19 nM, respectively).
T15105 Dexloxiglumide

Others Others
Dexloxiglumide, an active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8). It is a selective antagonist of cholecystokinin type A (CCKA) receptors.
T60700 Butabindide

Others Others
Butabindide (UCL-1397) 是三肽肽酶II (TPP II)的选择性抑制剂,对 TPP I 和TPP II 的Ki 值分别为 10 μM 和 7 nM。Butabindide 抑制 TPP II 以保护 CCK-8 免于失活。
T36629 Givinostat

Others Others
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF3056. At 25, 50, and 100 nM, Givinostat reduced IL-1β secretion more than 70%. Givinostat (ITF-2357) suppresses the production of IL-6 in PBMCs stimulated with TLR agonists as well as the combination of IL-12 plus IL-18. IL-6 secretion decreases to 50% at 50 nM Givinostat, but at 1...

化合物

Sincalide
Cat.No: TP1197
Synonym: SQ19844,辛卡利特,CCK-8,Cholecystokinin octapeptide
Target: Others
Sincalide ammonium
Cat.No: TP1198
Synonym: SQ19844 ammonium,CCK-8 ammonium,Cholecystokinin octapeptide ammonium
Target: cholecystokinin
N-Cbz-DL-tryptophan
Cat.No: T9343
Synonym:
Target: cholecystokinin
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
Cat.No: TP1931L1
Synonym: [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)
Target: cholecystokinin
Snf 8906
Cat.No: T34669
Synonym: Snf-8906,Snf8906
Target: Others
ARL 15849XX
Cat.No: T25108
Synonym: ARL15849XX,FPL15849,FPL-15849,FPL 15849,ARL-15849XX
Target: Others
Fpl 14294
Cat.No: T25437
Synonym: Fpl-14294,Fpl14294
Target: Others
Sograzepide
Cat.No: T16906
Synonym: YM-220,Netazepide,YF 476
Target: Others
Dexloxiglumide
Cat.No: T15105
Synonym:
Target: Others
Butabindide
Cat.No: T60700
Synonym:
Target: Others
Givinostat
Cat.No: T36629
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPK-00678 CALCA/CGRP Protein, Mouse, Recombinant (hFc)

CGRP,Katacalcin,PDN-21,CGRP-I,CGRP1,Calcitonin 1,Calcitonin,...

Mouse HEK293 Cells
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 assay, and osteogenic differentiation with osteogenic staining, qPCR, and repair of calvarial defect. Furthermore, 5-azacytidine (5-az) was used to intervene ASCs-T2DM to verify the relationship between the methylation level of the target fragment and expression of Calca.
TMPY-04123 CEACAM1 Protein, Human, Recombinant (His & hFc)

CEACAM‑1,carcinoembryonic antigen-related cell adhesion mole...

Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPJ-00808 CD45RA Protein, Human, Recombinant (His)

PTPRC,CD45R,CD45,LCA,protein tyrosine phosphatase, receptor ...

Human HEK293 Cells
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPH-01705 Mucin-1/MUC1 Protein, Human, Recombinant (Isoform 8, His)

Peanut-reactive urinary mucin,Isoform 8 of Mucin-1,...

Human E. coli
Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPY-00717 CEACAM1 Protein, Human, Recombinant (His)

CEACAM‑1,BGP1,BGP,carcinoembryonic antigen-related cell adhe...

Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8.
TMPJ-00828 Tau-F Protein, Human, Recombinant

Neurofibrillary tangle protein,Paired helical filament-tau,M...

Human E. coli
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are def...
TMPY-00668 APP/Protease nexin-II Protein, Human, Recombinant (hFc)

CTFγ,amyloid beta (A4) precursor protein,AAA,ABPP,CVAP,APPI,...

Human HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPY-06707 Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)

ADMCKD,PEMT,KL-6,ADMCKD1,H23AG,mucin 1, cell surface associa...

Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-01330 CD299 Protein, Human, Recombinant (His & Flag)

DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fami...

Human HEK293 Cells
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso...
TMPH-01683 Tau-F Protein, Human, Recombinant (HEK293, His)

Microtubule-associated protein tau,Paired helical filament-t...

Human HEK293 Cells
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the ...

重组蛋白

CALCA/CGRP Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00678
Species: Mouse
Expression System: HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-04123
Species: Human
Expression System: HEK293 Cells
CD45RA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00808
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (Isoform 8, His)
Cat.No: TMPH-01705
Species: Human
Expression System: E. coli
CEACAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00717
Species: Human
Expression System: HEK293 Cells
Tau-F Protein, Human, Recombinant
Cat.No: TMPJ-00828
Species: Human
Expression System: E. coli
APP/Protease nexin-II Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00668
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)
Cat.No: TMPY-06707
Species: Human
Expression System: HEK293 Cells
CD299 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-01330
Species: Human
Expression System: HEK293 Cells
Tau-F Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPH-01683
Species: Human
Expression System: HEK293 Cells
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