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Search Results for " camp "

Targets Recommended: cAMP PKA

311

抑制剂 & 化合物

61

天然产物

1

化合物库

44

重组蛋白

6

同位素标记化合物

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Cat. No.	Product Name
L7700	神经再生化合物库		524 compounds
	524 种神经再生相关化合物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

神经再生化合物库

Cat.No: L7700

Compounds: 524

Cat. No.	Product Name	Target	Signaling Pathways
T6747	8-Bromo-cAMP sodium salt 8-Br-Camp sodium salt,8-溴腺苷-3',5'-环单磷酸钠,8-Bromo-cAMP(sodium salt),8-Bromo-cAMP	PKA	Tyrosine Kinase/Adaptors
	8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) 是一种环 AMP (cAMP) 类似物，一种 cAMP 依赖性蛋白激酶 (PKA) 的激活剂。8-Bromo-cAMP sodium salt 具有抗肿瘤活性。
T1418	Bucladesine sodium dbcAMP,Dibutyryl-cAMP sodium salt,布拉地新钠盐,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt	PKA; PDE	Metabolism; Tyrosine Kinase/Adaptors
	Bucladesine sodium (DC2797) 是一种 cAMP 类似物，具有细胞渗透性。Bucladesine sodium 也是一种 cAMP 依赖性的蛋白激酶 (PKA) 激活剂，一种磷酸二酯 (PDE) 抑制剂。Bucladesine sodium 具有抗炎活性。
T35421	2'-O-Succinyl-cAMP	Others	Others
	2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2
T22529	6-Bnz-cAMP sodium salt	Others	Others
	6-Bnz-cAMP is a PKA-selective activator. It regulates the PKA dependent signaling pathways. The proliferative signaling pathway which activated by the 6-Bnz-cAMP involves activation of the epidermal growth factor receptor and ERK1/2. Extending the duratio
T22536	8-pCPT-2-O-Me-cAMP-AM	Others	Others
	Epac activator
T22014	8-CPT-2Me-cAMP, sodium salt	Others	Others
	8-CPT-2Me-cAMP sodium is a sodium salt compound that selectively activates exchange proteins activated by cAMP (Epac). These Epac proteins are cAMP-sensitive guanine nucleotide exchange factors (GEFs) responsible for activating small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium specifically activates Epac1 with an EC50 value of 2.2 μM, while showing no activation of PKA with an EC50 value greater than 10 μM [1]. Additionally, 8-CPT-2Me-cAMP sodium stimulates the Epac-mediated release of calcium ...
T83236	8-Azido-cAMP
	8-Azido-cAMP作为一种cAMP荧光模拟物，用于作为检测cAMP模式靶点的应用。该化合物是点击化学试剂，拥有Azide基团，能够通过铜催化的叠氮-炔环加成反应(CuAAc)与含Alkyne基团的分子发生反应。此外，它也能通过菌株促进的炔-叠氮环加成反应(SPAAC)与含有DBCO或BCN基团的分子进行反应。
T28990	Tocladesine NSC-614491,CN 1256,CN1256,8-Cl-cAMP,NSC614491,ICN-1256	Others	Others
	Tocladesine, a cyclic adenosine monophosphate (cAMP) receptor agonist, is used potentially for the treatment of colorectal cancer.
T11234	ESI-08	cAMP	GPCR/G Protein
	ESI-08 是 EPAC2 的有效拮抗剂，IC50 为 8.4 μM。 ESI-08 特异性阻断 cAMP 诱导的 EPAC 活化，但不阻断 cAMP 介导的 PKA 活化。
T11845	LGD-6972	Glucagon Receptor	GPCR/G Protein
	LGD-6972 是口服有活性的胰高血糖素受体选择性拮抗剂，能够用于研究 2 型糖尿病。
T15485	HJC0197	cAMP; Ras	GPCR/G Protein; MAPK
	HJC0197 是Epac1(cAMP 1 直接激活的交换蛋白) 和Epac2 拮抗剂，其对Epac2 的IC50值为5.9 μM。它在等浓度 cAMP 存在下能够降低 Epac1 介导的 Rap1-GDP 交换活性。它能够选择性阻断 cAMP 诱导的 Epac 活化。
T21865	BC 11-38	PDE	Metabolism
	BC 11-38是一种有效的PDE11生物活性抑制剂，可提高PKA 介导的 ATF-1 磷酸化、 H295R 细胞 cAMP 水平和皮质醇生成。
T15247	ESI-05 NSC 116966	cAMP	GPCR/G Protein
	ESI-05 (NSC-116966) 是特异性的 cAMP 直接激活交换蛋白 2 (EPAC2) 拮抗剂(IC50:0.4 µM)，能够抑制 cAMP 诱导的 EPAC2 的活化，并 EAPC2 介导的 Rap1 的活化。
T16136	MRS-1706	Adenosine Receptor	GPCR/G Protein; Neuroscience
	MRS-1706 是一种选择性A2B 腺苷受体的反向激动剂，对人 A2B、A2A、A1和 A3受体的Ki 值分别为 1.39、112、157 和 230 nM。
T8462	Enoximone 依诺昔酮,烯氟酮	PDE	Metabolism
	Enoximone 是一种选择性的，具有口服活性的磷酸二酯酶 III 抑制剂，也是正性肌力血管舒张剂。它通过抑制 cGMP 抑制的 PDE 来诱导血管舒张并增加细胞内 cAMP 水平。它还表现出 PDE4抑制作用，对心肌 PDE4A 的 IC50为 21.1 μM。它用于充血性心力衰竭的研究，并具有支气管扩张，抗哮喘和抗炎作用。
T9238	KI-7	Adenosine Receptor	GPCR/G Protein; Neuroscience
	KI-7 是一种A2B 腺苷受体阳性变构调节剂。它增强选择性 A2B 腺苷受体激动剂 BAY 60-6583 和腺苷诱导的 cAMP 积累，EC50分别为 2390 nM 和 2550 nM。它也增强非选择性 A2B 腺苷受体激动剂 NECA 诱导的 cAMP 积累，EC50为 445.8 nM。
T3174	Taprenepag CP-544326	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Taprenepag (CP-544326) 是一种有效的选择性前列腺素 E2 受体激动剂，EC50为 2.8 nM，可用于研究开角治疗高眼压和青光眼的试验。
T11723L	JNJ-39758979	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	JNJ-39758979是一种选择性的、高亲和力的、可口服的组胺 H4 受体拮抗剂，具有抗炎和止痒作用，对人、小鼠和猴子的组胺 H4 受体的 Ki 值分别为 12.5、5.3 和 25 nM。它对组胺诱导的 cAMP 抑制作用具有拮抗作用，pA2 为 7.9。
T0830	Bithionol 硫双二氯酚,Actamer,硫氯酚	cAMP; Parasite	GPCR/G Protein; Microbiology/Virology
	Bithionol (Actamer) 是一种抗寄生虫药物，对若干癌细胞有抑制作用。
T17232	Vidupiprant AMG 853	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Vidupiprant (AMG 853) 是一种有效的 CRTH2 和前列腺素 D 受体双重拮抗剂，在人源血浆中的 IC50 分别为 8 nM 和 35 nM。 Vidupiprant 可用于治疗哮喘的研究。
T13189	TP-10	PDE	Metabolism
	TP-10 是 PDE10A 对其他 PDE 的特异性抑制剂，IC50 为 0.8 nM。
T12103	MR-L2	PDE	Metabolism
	MR-L2 是可逆的、非竞争性的长型异构体磷酸二酯酶 -4激活剂，可以激活代表性的 PDE4 长型异构体 (PDE4A4、PDE4B1、PDE4C3、PDE4D5)。它可抑制 PGE2- 诱导的 MDCK 细胞囊肿形成，其EC50=1.2 µM。
T1671	Mirabegron YM178,米拉贝隆	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Mirabegron (YM178) 是选择性的肾上腺素受体激动剂，EC50=22.4 nM。
T12192	NCGC00229600	Others; TSH Receptor	GPCR/G Protein; Others
	NCGC00229600 是促甲状腺激素受体 (TSHR) 的变构反向激动剂。 NCGC00229600 抑制 TSH 和刺激 TSHR 的内源性激活抗体，可用于格雷夫斯病的研究。
T6022	LY404039 pomaglumetad	Glucocorticoid Receptor; GluR	Endocrinology/Hormones; Neuroscience
	LY404039 (pomaglumetad) 是可口服的mGluR2和mGluR3选择性激动剂，有抗精神病和抗焦虑的作用。它对重组人mGluR2和mGluR3的Ki 分别为 149 和 92 nM，比对其他受体/转运蛋白的抑制性高 100 倍以上。
T3478	Ro 67-7476	GluR	Neuroscience
	Ro 67-7476 是mGluR1的正变位调节剂，能增强表达 rat mGluR1a 的 HEK293 细胞中谷氨酸诱导的钙释放，EC50为 60.1 nM。它是 P-ERK1/2 激动剂，可以在外源添加谷氨酸的情况下激活 ERK1/2 磷酸化 (EC50=163.3 nM)。
T23256	RS-25344 hydrochloride	PDE	Metabolism
	RS 25344 hydrochloride 是 cAMP-磷酸二酯酶 4 的选择性抑制剂，在人淋巴细胞中的 IC50为 0.28 nM，对 PDE I、II、III 仅具有微弱的抑制作用，IC50分别为 >100 μM、160 μM、330 μM。它具有抗炎、增强记忆力和认知能力以及抗肿瘤活性。
T3183	SAX-187 WAY 181187,WAY181187	5-HT Receptor	GPCR/G Protein; Neuroscience
	SAX-187 (SAX-187) 是一种有效的选择性5-HT6受体激动剂，Ki 为 2.2 nM，EC50为 6.6 nM。它介导 5-HT6 受体依赖性信号通路，可作为特异性激动剂。
T23204	PSN 375963 PSN 375963 hydrochloride	GPR	Endocrinology/Hormones; GPCR/G Protein
	PSN 375963 (PSN 375963 hydrochloride) hydrochloride 是GPR119激动剂，对人和小鼠的EC50分别为 8.4 和 7.9 μM。它表现出与内源性油酰乙醇酰胺 (OEA) 相似的效力。
T6649	(S)-(+)-Rolipram (S)-Rolipram,(+)-Rolipram,盐酸环胞苷,S- (+)-Rolipram	Apoptosis; PDE	Apoptosis; Metabolism
	(S)-(+)-Rolipram ((+)-Rolipram) 是一种 cAMP 依赖性磷酸二酯酶 4 (PDE4) 抑制剂，IC50=1100 nM。它能够抑制人单核细胞产生的肿瘤坏死因子 α (TNFα)。
T23154	Piclamilast RPR 73401,RP 73401,吡拉米司特	PDE	Metabolism
	Piclamilast (RP 73401) 是一种有效的磷酸二酯酶 4(PDE4)的抑制剂，对猪主动脉和可溶性嗜酸性粒细胞中的 IC50值分别为 16 nM 和 2 nM。
T14975	CJ-42794 CJ-042794	Others	Others
	CJ-42794 (CJ-042794)是前列腺素受体 EP4的选择性拮抗剂, 抑制[3H]-PGE2与 EP4受体结合的平均 pKi 为8.5, 对 EP4选择性比 EP1, EP2和 EP3高200多倍。
TP1187	C-Type Natriuretic Peptide (CNP) (1-22), human CNP (1-22), human	RAAS	Endocrinology/Hormones
	C-Type Natriuretic Peptide (CNP) (1-22), human 是一种利钠肽受体 B (NPR-B) 激动剂，是一种 CNP 的 1-22 片段。它对生理激动剂组胺和 5-HT 刺激或直接由 Forskolin 刺激的 cAMP 合成具有抑制作用。其中CNP 是一种有效的、内皮衍生的松弛剂和生长抑制因子。
T14069	A-3 hydrochloride	CaMK; Casein Kinase; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Neuroscience; Stem Cells; Tyrosine Kinase/Adaptors
	A-3 hydrochloride 是一种细胞可渗透的、可逆的、ATP 竞争性非选择性拮抗剂。它抑制 PKA 、酪蛋白激酶 II 和肌球蛋白轻链激酶，Ki 值分别为4.3 µM、5.1 µM 和7.4 µM。它还抑制 PKC 和酪蛋白激酶 I 的活性，Ki 分别为 47 µM 和 80 µM。
T3520	Setipiprant KYTH-105,塞替匹仑,ACT-129968	GPR; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
	Setipiprant (ACT-129968) 是一种口服的选择性 CRTH2 拮抗剂，IC50为6.0 nM。
T19706	Ro 20-1724 Ro-20-1724,4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone,Ro20-1724	PDE	Metabolism
	Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) 是 cAMP 特异性磷酸二酯酶抑制剂 b>(PDE4/PDE IV)，其 Ki=1930 nM，具有神经保护作用。
T1673	Acamprosate calcium calcium acetylhomotaurinate,N-Acetylhomotaurine Calcium,Alcomed,阿坎酸钙,Sobriol,Campral EC,Calcium N-acetylhomotaurinate	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Acamprosate calcium (Campral EC) 是 GABA 受体激动剂和谷氨酸能系统调节剂，用于治疗酒精依赖。
T7465	4-Methylbenzylidene camphor Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC	AChE	Neuroscience
	4-Methylbenzylidene camphor 是有机的樟脑衍生物，应用于化妆品行业，具有保护皮肤抵抗紫外线（特别是紫外线B 辐射）的能力。
T28615	Sp-cAMPS Rp-cAMPS TEA,Rp cAMPS TEA,Rp-cAMPS TEA salt,Rp cAMPS TEA salt	Others	Others
	Rp-cAMPS TEA salt is a cAMP-dependent protein kinase (PKA) activator.
T36678	Rp-8-CPT-cAMPS sodium	Others	Others
	Rp-8-CPT-cAMP is a structural combination of the lipophilic and non-hydrolyzable cAMP analogs, 8-CPT-cyclic AMP and Rp-cyclic AMPS .[1] It functions as a site-selective inhibitor of protein kinase A (PKA) type I and II, with preference towards site A of type I and site B of type II.2 By occupying cAMP binding sites at the regulatory subunit of PKA, Rp-8-CPT-cAMP prevents the kinase holoenzyme from dissociative activation.[2],[3]
T22621	Rp-cAMPS cAMPS-Sp, triethylammonium salt	Others	Others
	Rp-cAMPS 竞争性抑制 cAMP 诱导的 cAMP 依赖性蛋白激酶激活。
T12764	Rp-cAMPS triethylammonium salt	Others	Others
	Rp-cAMPS triethylammonium salt is an analog of cAMP.It acts as a potent, competitive and cell-permeable antagonist of cAMP-induced activation of cAMP-dependent PKA I and II with Kis of 6.05 µM and 9.75 µM, respectively.
T36679	Rp-cAMPS sodium salt	Others	Others
	Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis by phosphodiesterases[1][2][3][4][5][6]. A membrane-permeable competitive cAMP antagonist (Rp-cAMPS) that blocks PKA activation by binding to the regulatory subunits without dissociating the kinase holoenzyme also inhibits synaptic plasticity but has no effect on normal synaptic t...
T38696	Rp-8-CPT-cAMPS	Others	Others
	Rp-8-CPT-cAMPS is a powerful and competitive antagonist of cAMP-induced activation of cAMP-dependent protein kinase (PKA) I and II. Acting as a potent cAMP analog, Rp-8-CPT-cAMPS exhibits a preference for site A of RI over site A of RII. Additionally, it favors site B of RII over site B of RI. This compound effectively inhibits cAMP-dependent PKA activation and demonstrates selectivity in binding to specific sites within the protein kinase.
T73708	Sp-cAMPS triethylamine	Others	Others
	Sp-cAMPS triethylamine，一种 cAMP 类似物，是一种依赖 cAMP 的PKAI 和PKAII 的有效激活剂。Sp-cAMPS triethylamine 还是一种有效的竞争性磷酸二酯酶 (PDE3A) 抑制剂，Ki 为 47.6 µM。Sp-cAMPS triethylamine 以EC50为 40 μM 来结合PDE10GAF 域。
T38694	Sp-8-CPT-cAMPS	Others	Others
	Sp-8-CPT-cAMPS is a powerful and specific cAMP analog that activates cAMP-dependent protein kinase A (PKA I and PKA II) selectively and effectively. It exhibits a 153-fold preference for site A of RI over site A of RII, and a 59-fold preference for site B of RII over site B of RI.
T80147	EcAMP3
	EcAMP3为发夹样多肽，具备抗真菌及抗菌活性。该EcAMPs前体家族特征为包含相同的七个半胱氨酸基序，结构为：C1XXXC2(11–13)C3XXXC4。
T79883	9-Chloromethyl-10-hydroxy-11-F-Camptothecin	Topoisomerase	DNA Damage/DNA Repair
	9-Chloromethyl-10-Hydroxy-11-F-Camptothecin是一款喜树碱类衍生化合物，具有DNA拓扑异构酶I (Topo I)抑制活性，应用于癌症治疗的研究领域。
T66944	(1R)-(-)-10-Camphorsulfonic acid	Others	Others
	(1R)-(-)-10-Camphorsulfonic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66944，CAS号为 35963-20-3。
T73059	Acamprosate	Others	Others
	Acamprosate 是一种口服活性原型神经调节剂。Acamprosate 可用于酒精依赖和酒精中毒的研究。

化合物

8-Bromo-cAMP sodium salt

Cat.No: T6747

Synonym: 8-Br-Camp sodium salt,8-溴腺苷-3',5'-环单磷酸钠,8-Bromo-cAMP(sodium salt),8-Bromo-cAMP

Target: PKA

Bucladesine sodium

Cat.No: T1418

Synonym: dbcAMP,Dibutyryl-cAMP sodium salt,布拉地新钠盐,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt

Target: PKA, PDE

2'-O-Succinyl-cAMP

Cat.No: T35421

Target: Others

6-Bnz-cAMP sodium salt

Cat.No: T22529

Target: Others

8-pCPT-2-O-Me-cAMP-AM

Cat.No: T22536

Target: Others

8-CPT-2Me-cAMP, sodium salt

Cat.No: T22014

Target: Others

Cat.No: T83236

Cat.No: T28990

Synonym: NSC-614491,CN 1256,CN1256,8-Cl-cAMP,NSC614491,ICN-1256

Target: Others

Cat.No: T11234

Target: cAMP

Cat.No: T11845

Target: Glucagon Receptor

Cat.No: T15485

Target: cAMP, Ras

Cat.No: T21865

Target: PDE

Cat.No: T15247

Synonym: NSC 116966

Target: cAMP

Cat.No: T16136

Target: Adenosine Receptor

Cat.No: T8462

Synonym: 依诺昔酮,烯氟酮

Target: PDE

Cat.No: T9238

Target: Adenosine Receptor

Cat.No: T3174

Synonym: CP-544326

Target: Prostaglandin Receptor

Cat.No: T11723L

Target: Histamine Receptor

Cat.No: T0830

Synonym: 硫双二氯酚,Actamer,硫氯酚

Target: cAMP, Parasite

Cat.No: T17232

Synonym: AMG 853

Target: Prostaglandin Receptor

Cat.No: T13189

Target: PDE

Cat.No: T12103

Target: PDE

Cat.No: T1671

Synonym: YM178,米拉贝隆

Target: Adrenergic Receptor

Cat.No: T12192

Target: Others, TSH Receptor

Cat.No: T6022

Synonym: pomaglumetad

Target: Glucocorticoid Receptor, GluR

Cat.No: T3478

Target: GluR

RS-25344 hydrochloride

Cat.No: T23256

Target: PDE

Cat.No: T3183

Synonym: WAY 181187,WAY181187

Target: 5-HT Receptor

Cat.No: T23204

Synonym: PSN 375963 hydrochloride

Target: GPR

(S)-(+)-Rolipram

Cat.No: T6649

Synonym: (S)-Rolipram,(+)-Rolipram,盐酸环胞苷,S- (+)-Rolipram

Target: Apoptosis, PDE

Cat.No: T23154

Synonym: RPR 73401,RP 73401,吡拉米司特

Target: PDE

Cat.No: T14975

Synonym: CJ-042794

Target: Others

C-Type Natriuretic Peptide (CNP) (1-22), human

Cat.No: TP1187

Synonym: CNP (1-22), human

Target: RAAS

A-3 hydrochloride

Cat.No: T14069

Target: CaMK, Casein Kinase, PKA, PKC

Cat.No: T3520

Synonym: KYTH-105,塞替匹仑,ACT-129968

Target: GPR, Prostaglandin Receptor

Cat.No: T19706

Synonym: Ro-20-1724,4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone,Ro20-1724

Target: PDE

Acamprosate calcium

Cat.No: T1673

Synonym: calcium acetylhomotaurinate,N-Acetylhomotaurine Calcium,Alcomed,阿坎酸钙,Sobriol,Campral EC,Calcium N-acetylhomotaurinate

Target: GABA Receptor

4-Methylbenzylidene camphor

Cat.No: T7465

Synonym: Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC

Target: AChE

Cat.No: T28615

Synonym: Rp-cAMPS TEA,Rp cAMPS TEA,Rp-cAMPS TEA salt,Rp cAMPS TEA salt

Target: Others

Rp-8-CPT-cAMPS sodium

Cat.No: T36678

Target: Others

Cat.No: T22621

Synonym: cAMPS-Sp, triethylammonium salt

Target: Others

Rp-cAMPS triethylammonium salt

Cat.No: T12764

Target: Others

Rp-cAMPS sodium salt

Cat.No: T36679

Target: Others

Rp-8-CPT-cAMPS

Cat.No: T38696

Target: Others

Sp-cAMPS triethylamine

Cat.No: T73708

Target: Others

Sp-8-CPT-cAMPS

Cat.No: T38694

Target: Others

Cat.No: T80147

9-Chloromethyl-10-hydroxy-11-F-Camptothecin

Cat.No: T79883

Target: Topoisomerase

(1R)-(-)-10-Camphorsulfonic acid

Cat.No: T66944

Target: Others

Cat.No: T73059

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TCO2745	Cyclic AMP Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate	Others; Endogenous Metabolite	Metabolism; Others
	Cyclic AMP (cAMP)(Adenosine 3',5'-cyclophosphate) 是有丝分裂信使，可以促进 G1期到 S 期的细胞周期进程。
T2939	Forskolin 毛喉素,Coleonol,Colforsin	FXR; Adenylyl cyclase; AChR; Autophagy	Autophagy; Metabolism; Neuroscience
	Forskolin (Coleonol) 属于天然产物，是一种腺苷酸环化酶激活剂 (EC50=0.5 μM)。Forskolin 可以增加 cAMP 水平，可以激活 PXR 和 FXR，也可以诱导细胞自噬。Forskolin 对心脏产生正性肌力作用，具有血小板抗凝集和降压作用。
T5S2059	Glaucine	Calcium Channel; Dopamine Receptor; Influenza Virus; Adrenergic Receptor; PDE	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	Glaucine 是从海罂粟中分离的一种生物碱，具有镇咳、抗炎和支气管扩张作用。它是具有口服活性的磷酸二酯酶 4 选择性抑制剂。它还是非选择性的 α-肾上腺素受体拮抗剂，具有抗氧化和抗病毒活性。
T4S0792	Pinoresinol 4-O-β-D-glucopyranoside (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside	Others; Antioxidant	Others; oxidation-reduction
	(+)-pinoresinol-β-D-glucoside; (+)-pinor 是连翘中主要的活性呋喃类木脂素。它显示出抗氧化、降血压和环磷酸腺苷 (cAMP) 磷酸二酯酶抑制活性。
TMS2262	(-)-CAMPHOR L-Camphor,左旋樟脑	Others	Others
	(-)-CAMPHOR (L-Camphor) 是樟脑的手性中间体，在食品中用作风味添加剂和甜味剂。
T4952	9-Hydroxycamptothecin 9-HCPT,9-羟基喜树碱,10-Hydroxycampothecin	Topoisomerase	DNA Damage/DNA Repair
	9-Hydroxycampothecin 是具有抗癌活性的喜树碱衍生物。
T4S2157	Campesterol 菜油甾醇,(24R)-5-Ergosten-3β-ol	Endogenous Metabolite	Metabolism
	Campesterol ((24R)-5-Ergosten-3β-ol) 是一种植物甾醇，具有降胆固醇和抗癌的活性。
T2764	(S)-10-Hydroxycamptothecin 10-羟喜树碱,10-羟基喜树碱,10-Hydroxycamptothecin,10-HCPT	Apoptosis; Topoisomerase	Apoptosis; DNA Damage/DNA Repair
	(S)-10-Hydroxycamptothecin (10-HCPT) 是一种从喜树中分离的 DNA 拓扑异构酶 I 抑制剂。它显著诱导细胞凋亡，可研究肝癌、胃癌、结肠癌和白血病。
T5S1952	9-Methoxycamptothecin	Apoptosis; Topoisomerase	Apoptosis; DNA Damage/DNA Repair
	9-Methoxycamptothecin 是从臭味假柴龙树中分离得到的一种天然产物，通过抑制拓扑异构酶起到抗肿瘤作用，具有强效的诱导 G2/M 期细胞和癌细胞凋亡的作用。
T1123	Camptothecin NSC-100880,Campathecin,喜树碱,(S)-(+)-Camptothecin,CPT	Apoptosis; Influenza Virus; Topoisomerase; Antibiotic; Antifungal; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; DNA Damage/DNA Repair; Microbiology/Virology
	Camptothecin (CPT) 属于生物碱类天然产物，是一种 DNA 拓扑异构酶 I (Topo I) 的抑制剂 (IC50=679 nM)，具有特异性。Camptothecin 具有抗肿瘤活性，可以诱导细胞凋亡。
T1521	(±)-10-Hydroxycamptothecin Hydroxy Camptothecine,10-羟基喜树碱,10-Hydroxycamptothecin	Topoisomerase	DNA Damage/DNA Repair
	(±)-10-Hydroxycamptothecin (Hydroxy Camptothecine) 是一种从喜树茎木中分离出来的生物碱，抑制拓扑异构酶 I 活性，具有广谱抗肿瘤活性。
T4S1951	10-Methoxycamptothecin	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	10-Methoxycamptothecin 是分离自喜树的喜树碱衍生物，具有高抗癌特性。通过对 2774 细胞系的抗肿瘤活性测定，发现它比 10-羟基喜树碱的细胞毒性更高。
T3S1955	7-Ethylcamptothecin	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	7-Ethylcamptothecin 是一种喜树碱类似物。其中喜树碱是一种细胞毒性生物碱，从喜树中分离出得到，对 L1210 白血病和 Walker 256 癌肉瘤模型具有很强的抗肿瘤活性。
T7959	(+)-ISOPINOCAMPHEOL	Others	Others
	(+)-ISOPINOCAMPHEOL 是一种天然产物。
T20191	(-)-Camphoric acid (-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)-	GluR	Neuroscience
	(-)-Camphoric acid (L-Camphoric acid) 是一种活性较低的樟脑酸对映异构体，樟脑酸可诱导 GluR 表达。
T0882	(+)-Camphor D-(+)-Camphor,D-Camphor,(+)-樟脑,(1R)-(+)-Camphor	Antibacterial; TRP/TRPV Channel	Membrane transporter/Ion channel; Microbiology/Virology
	(+)-Camphor (D-Camphor) 是一种食品添加剂，在医学上可用作防腐剂。
T40179	Sodium Camptothecin	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Sodium Camptothecin 是一种植物生物碱，具有抗肿瘤活性。它是可逆 RNA 合成抑制剂，可以抑制腺病毒的复制。它能抑制 DNA 合成，并引起细胞内预形成的病毒 DNA 断裂。
T2952	Camphor 樟脑,(±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa	Influenza Virus; TRP/TRPV Channel	Membrane transporter/Ion channel; Microbiology/Virology
	Camphor (2-Camphanone) 是一种双环单萜酮，广泛存在于植物中，尤其是樟脑。它是一种激动剂，局部用作皮肤止痒剂和抗感染剂，具有抗病毒，镇咳和抗癌活性。
TN1176	10-Nitro-camptothecin 9-硝基喜树碱	Others	Others
	10-Nitro-camptothecin is a natural product
TN4667	Norcamphor	Others	Others
	Norcamphor 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4667，CAS号为 497-38-1。
T82002	Juniper camphor
	Juniper camphor为倍半萜烯类化合物，可通过分馏樟脑蓝油的高沸点馏分进行分离。
T82786	Campneoside II	Others	Others
	Campneoside II, 分离自毛泡桐，展现出显著的抗补体活性。
TN5830	Campsiketalin Rengyoxide dimethyl ketal
	Campsiketalin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5830，CAS号为 93675-96-8。
T83520	(S)-Campesterol 5-Ergosten-3β-ol
	(S)-Campesterol (5-Ergosten-3β-ol)，一种植物甾醇，存在于多种食物和植物源中，对人体健康具有潜在益处。
TN2460	12-Ethyl-9-hydroxycamptothecin 7-乙基-10-羟基喜树碱,7-Ethyl-10-Hydroxy-Camptothecin	Others	Others
	12-Ethyl-9-hydroxycamptothecin 是一种 Camptothecin 的衍生物。其中Camptothecin (CPT) 是一种生物碱，也是 DNA 拓扑异构酶I 抑制剂(IC50:679 nM)。
TN3091	5,7-Diacetoxy-8-methoxyflavone ZINC77031696	PDE	Metabolism
	5,7-Diacetoxy-8-methoxyflavone 源自黄芩的根，可抑制 cAMP 磷酸二酯酶。
T41122	1,3-Dihydroxyacetone	Endogenous Metabolite	Metabolism
	1,3-Dihydroxyacetone 是防晒美黑护肤制剂的主要活性成分，是合成各种精细化学品的重要前体，也是一种食品添加剂，可通过在 Gluconobacter oxydans 上进行微生物发酵实现工业规模生产。1,3-Dihydroxyacetone 具有提高cAMP 水平的能力。
T19122	3-Methylvaleric Acid	Others; Endogenous Metabolite	Metabolism; Others
	3-Methylvaleric Acid 是一种食用级香料，存在于烟草中。3-Methylvaleric Acid 可增强 CHO-K1细胞和HEK293细胞中的细胞内cAMP 积累和CRE-荧光素酶活性。
TN1266	3-O-Methylquercetin	IL Receptor; cAMP; PDE	GPCR/G Protein; Immunology/Inflammation; Metabolism
	3-O-Methylquercetin 是分离自植物Rhamnus nakaharai 的天然产物，可抑制总 cAMP 和cGMP-phosphodiesterase (PDE)。它对PDE1、PDE5、PDE 和PDE4的IC50分别是31.9 μM、86.9 μM、18.6 μM 和1.6 μM。
TQ0216	Ercalcitriol 1α,25-Dihydroxy Vitamin D2	Others	Others
	Ercalcitriol (1α,25-Dihydroxy Vitamin D2) 是维生素 D2 的活性代谢物。 Ercalcitriol 作为维生素 D 的生理活化形式，通过调节正常细胞和转化细胞中的导管素抗菌肽 (CAMP) 和防御素 β-4 (DEFB4) 基因来增强免疫力，从而对抗病原体感染。
T5081	Adenine monohydrochloride hemihydrate 腺嘌呤盐酸盐,Adenine hydrochloride hydrate,6-Aminopurine hydrochloride hydrate	Endogenous Metabolite; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Adenine monohydrochloride hemihydrate 是内源性代谢产物的一种。
T5S2178	Fargesin 辛夷脂素,(+/-)-Fargesin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fargesin ((+/-)-Fargesin) 是一种活性新木脂素，从木兰植物中分离得到，具有抗高血压和抗炎活性。
T2890	Hordenine	Antibacterial; Antibiotic	Microbiology/Virology
	Hordenine 是一种植物中发现的苯乙胺生物碱，可抑制 cAMP 产生起到抑制黑色素生成的作用。
T4973	Paraxanthine 1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE	Endogenous Metabolite	Metabolism
	Paraxanthine (1,7-dimethylxanthine) 是一种 caffeine 的代谢物，能够刺激Ryanodine 受体通道来抑制多巴胺能细胞的死亡。
TN3466	Atherosperminine	cAMP; Calcium Channel; AChR; Parasite	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	Atherosperminine 是一种天然生物碱，在体外表现出抗疟原虫活性，IC50为 5.80 μM。它具有DPPH 自由基清除活性，其IC50值为 29.56 µg/mL。它对气管有非特异性的弛缓作用。它是一种良好的还原剂，具有螯合金属的能力。
T1626	Prostaglandin E1 前列地尔,PGE1,列腺素E1,Alprostadil	Endogenous Metabolite; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism
	Prostaglandin E1 (Alprostadil) 是一种前列腺素受体配体，对小鼠 EP1、EP2、EP3、EP4和 IP 的 Ki 值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集，可作为血管扩张剂用于外周血管疾病的研究。
T0892	Diphylline 二羟丙茶碱,Dyphylline,Diprophylline	PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Diphylline (Diprophylline) 是一种A1/A2腺苷受体拮抗剂，也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物，具有支气管扩张和血管扩张作用，有用于治疗慢性支气管炎和肺气肿的潜力。
TN1334	7-Methoxyrosmanol 7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol	cAMP	GPCR/G Protein
	7-Methoxyrosmanol (7-O-Methylrosmanol) 是一种酚类二萜，从迷迭香中分离得到，可抑制 PEPCK 和 G6Pase 启动子的 cAMP 反应。
TN3013	4,5-Dimethoxycanthin-6-one Methylnigakinone	P450; Antibacterial; PDE	Metabolism; Microbiology/Virology
	4,5-Dimethoxycanthin-6-one 从 Picrasma quassioides BENNET (Simaroubaceae)是一种从 Picrasma quassioides BENNET (Simaroubaceae) 中分离得到生物碱。4,5-Dimethoxycanthin-6-one 是一种有效的、非竞争性的 CYP1A2 介导的 phenacetin O-deethylation 抑制剂（IC50 ： 1.7 μM, Ki ： 2.6 μM），对环磷酸腺苷（cAMP）磷酸二酯酶有很强的抑制作用。4,5-Dimethoxycanthin-6-one 具有抗菌活性，对金黄色葡萄球菌及其耐药菌株有抑制作用。4,5-Dimethoxycanthin-6-one 对肿瘤细胞株 U937 和 HepG2 具有细胞毒性。
T6427	Butein 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因	Apoptosis; EGFR; Others; PDE; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Others; Tyrosine Kinase/Adaptors
	Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂，也是蛋白酪氨酸激酶抑制剂，还是一种SIRT1激活剂。它通过 AKT 和 ERK/p38 MAPK 通路，靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
T2205	Acefylline Theophylline-7-acetic acid,茶碱乙酸,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid	TNF; PAD; PKA; HDAC; PDE; Adenosine Receptor	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
	Acefylline (Theophylline-7-acetic acid) 是黄嘌呤衍生物，是一种腺苷受体拮抗剂。它是蛋白质精氨酸脱亚氨酶 (PAD) 激活剂，也是一种支气管扩张剂，可抑制大鼠肺 cAMP 磷酸二酯酶同工酶。
T3826	Polygalasaponin F 异牡荆苷,瓜子金皂苷己	NF-κB; TLR; Akt; PI3K	Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR signaling
	Polygalasaponin F 是从瓜子金中提取的齐墩果烷型三萜皂苷，可通过调节TLR4-PI3K/AKT-NF-kB 信号通路减少神经炎症细胞因子的分泌，能降低炎性细胞因子肿瘤坏死因子 α 的释放。
T4S2128	Bilobetin 白果双黄酮,白果素	PKA; PPAR	DNA Damage/DNA Repair; Metabolism; Tyrosine Kinase/Adaptors
	Bilobetin 是银杏的活性成分，可改善胰岛素抵抗，增加肝脏对脂质的吸收和氧化，降低极低密度脂蛋白甘油三酯分泌和血液甘油三酯水平，增强组织中 β-氧化的酶的表达和活性，并减弱甘油三酯及其代谢产物的积累。它还增加了 PPARα的磷酸化，核转位和活性，并伴随着 cAMP 水平和 PKA 活性的升高。
TN1088	3,5,6,7,8,3',4'-Heptemthoxyflavone 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮	Others	Others
	3,5,6,7,8,3',4'-Heptemthoxyflavone 是来自蜜柑皮中的黄酮，具有抗肿瘤起始活性和抗神经炎症作用。它能通过 cAMP/ERK/CREB 信号诱导脑源性神经营养因子表达，降低 C6 细胞磷酸二酯酶活性。它能抑制胶原酶的活性，增加人真皮成纤维细胞新生细胞中 I 型前胶原含量。
T29462	5-OH-HxMF
	5-OH-HxMF is an inducer of neurite growth in PC12 cells through the camp / PKA / CREB pathway.
TN4073	Forskolin G	Others	Others
	Forskolin is known to elevate intracellular cAMP levels.
TN7468	Mahuannin B	Others	Others
	Mahuannin B effectively reduces sweating by inhibiting cAMP production through the suppression of adenylate cyclase (AC) activity.
TN4317	Isopedicin	NADPH-oxidase; cAMP; p38 MAPK; PKA; JNK; PDE	GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism; Tyrosine Kinase/Adaptors
	Isopedicin has anti-inflammatory functions, it inhibits the O(2)()(-) production in human neutrophils by an elevation of cellular cAMP* and activation of PKA through its inhibition of cAMP-specific PDE.
TN1504	Citreorosein 羟基大黄素	cAMP; NF-κB; PI3K	GPCR/G Protein; NF-κB; PI3K/Akt/mTOR signaling
	Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation.
T13762	Luteolin 7-sulfate	Others	Others
	Luteolin 7-sulfate, derived from the marine plant Phyllospadix iwatensis Makino, suppresses TYR gene expression by intervening in a signaling pathway involving the cAMP-responsive element binding protein (CREB) and microphthalmia-associated transcription factor (MITF). This inhibition ultimately leads to a decrease in melanin synthesis.
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天然产物

Cat.No: TCO2745

Synonym: Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate

Target: Others, Endogenous Metabolite

Cat.No: T2939

Synonym: 毛喉素,Coleonol,Colforsin

Target: FXR, Adenylyl cyclase, AChR, Autophagy

Cat.No: T5S2059

Target: Calcium Channel, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, PDE

Pinoresinol 4-O-β-D-glucopyranoside

Cat.No: T4S0792

Synonym: (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside

Target: Others, Antioxidant

Cat.No: TMS2262

Synonym: L-Camphor,左旋樟脑

Target: Others

9-Hydroxycamptothecin

Cat.No: T4952

Synonym: 9-HCPT,9-羟基喜树碱,10-Hydroxycampothecin

Target: Topoisomerase

Cat.No: T4S2157

Synonym: 菜油甾醇,(24R)-5-Ergosten-3β-ol

Target: Endogenous Metabolite

(S)-10-Hydroxycamptothecin

Cat.No: T2764

Synonym: 10-羟喜树碱,10-羟基喜树碱,10-Hydroxycamptothecin,10-HCPT

Target: Apoptosis, Topoisomerase

9-Methoxycamptothecin

Cat.No: T5S1952

Target: Apoptosis, Topoisomerase

Cat.No: T1123

Synonym: NSC-100880,Campathecin,喜树碱,(S)-(+)-Camptothecin,CPT

Target: Apoptosis, Influenza Virus, Topoisomerase, Antibiotic, Antifungal, ADC Cytotoxin

(±)-10-Hydroxycamptothecin

Cat.No: T1521

Synonym: Hydroxy Camptothecine,10-羟基喜树碱,10-Hydroxycamptothecin

Target: Topoisomerase

10-Methoxycamptothecin

Cat.No: T4S1951

Target: Others, ADC Cytotoxin

7-Ethylcamptothecin

Cat.No: T3S1955

Target: Others, ADC Cytotoxin

(+)-ISOPINOCAMPHEOL

Cat.No: T7959

Target: Others

(-)-Camphoric acid

Cat.No: T20191

Synonym: (-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)-

Target: GluR

Cat.No: T0882

Synonym: D-(+)-Camphor,D-Camphor,(+)-樟脑,(1R)-(+)-Camphor

Target: Antibacterial, TRP/TRPV Channel

Sodium Camptothecin

Cat.No: T40179

Target: DNA/RNA Synthesis

Cat.No: T2952

Synonym: 樟脑,(±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa

Target: Influenza Virus, TRP/TRPV Channel

10-Nitro-camptothecin

Cat.No: TN1176

Synonym: 9-硝基喜树碱

Target: Others

Cat.No: TN4667

Target: Others

Juniper camphor

Cat.No: T82002

Campneoside II

Cat.No: T82786

Target: Others

Campsiketalin

Cat.No: TN5830

Synonym: Rengyoxide dimethyl ketal

(S)-Campesterol

Cat.No: T83520

Synonym: 5-Ergosten-3β-ol

12-Ethyl-9-hydroxycamptothecin

Cat.No: TN2460

Synonym: 7-乙基-10-羟基喜树碱,7-Ethyl-10-Hydroxy-Camptothecin

Target: Others

5,7-Diacetoxy-8-methoxyflavone

Cat.No: TN3091

Synonym: ZINC77031696

Target: PDE

1,3-Dihydroxyacetone

Cat.No: T41122

Target: Endogenous Metabolite

3-Methylvaleric Acid

Cat.No: T19122

Target: Others, Endogenous Metabolite

3-O-Methylquercetin

Cat.No: TN1266

Target: IL Receptor, cAMP, PDE

Cat.No: TQ0216

Synonym: 1α,25-Dihydroxy Vitamin D2

Target: Others

Adenine monohydrochloride hemihydrate

Cat.No: T5081

Synonym: 腺嘌呤盐酸盐,Adenine hydrochloride hydrate,6-Aminopurine hydrochloride hydrate

Target: Endogenous Metabolite, Adenosine Receptor

Cat.No: T5S2178

Synonym: 辛夷脂素,(+/-)-Fargesin

Target: Adrenergic Receptor

Cat.No: T2890

Target: Antibacterial, Antibiotic

Cat.No: T4973

Synonym: 1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE

Target: Endogenous Metabolite

Atherosperminine

Cat.No: TN3466

Target: cAMP, Calcium Channel, AChR, Parasite

Prostaglandin E1

Cat.No: T1626

Synonym: 前列地尔,PGE1,列腺素E1,Alprostadil

Target: Endogenous Metabolite, Prostaglandin Receptor

Cat.No: T0892

Synonym: 二羟丙茶碱,Dyphylline,Diprophylline

Target: PDE, Adenosine Receptor

7-Methoxyrosmanol

Cat.No: TN1334

Synonym: 7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol

Target: cAMP

4,5-Dimethoxycanthin-6-one

Cat.No: TN3013

Synonym: Methylnigakinone

Target: P450, Antibacterial, PDE

Cat.No: T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因

Target: Apoptosis, EGFR, Others, PDE, Autophagy

Cat.No: T2205

Synonym: Theophylline-7-acetic acid,茶碱乙酸,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid

Target: TNF, PAD, PKA, HDAC, PDE, Adenosine Receptor

Polygalasaponin F

Cat.No: T3826

Synonym: 异牡荆苷,瓜子金皂苷己

Target: NF-κB, TLR, Akt, PI3K

Cat.No: T4S2128

Synonym: 白果双黄酮,白果素

Target: PKA, PPAR

3,5,6,7,8,3',4'-Heptemthoxyflavone

Cat.No: TN1088

Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮

Target: Others

Cat.No: T29462

Cat.No: TN4073

Target: Others

Cat.No: TN7468

Target: Others

Cat.No: TN4317

Target: NADPH-oxidase, cAMP, p38 MAPK, PKA, JNK, PDE

Cat.No: TN1504

Synonym: 羟基大黄素

Target: cAMP, NF-κB, PI3K

Luteolin 7-sulfate

Cat.No: T13762

Target: Others

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01309	PKI-Beta Protein, Human, Recombinant (His) PRKACN2,PKI-beta,PKI-β,cAMP-Dependent Protein Kinas...	Human	E. coli
	cAMP-Dependent Protein Kinase Inhibitor β (PKI-β) is a member of the PKI family. As a member of the cAMP-dependent protein kinase inhibitor family,It has been shown that PKI-β is an extremely potent competitive inhibitor of cAMP-dependent protein kinase activity; this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. It may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and...
TMPY-06476	CAMP Factor Protein, Cutibacterium acnes, Recombinant (His)	Cutibacterium acnes	Baculovirus Insect Cells
	CAMP factor is an extracellular cytolytic protein produced by Streptococcus agalactiae. CAMP factor binds the Fc fragments of IgG and is also known as protein B, in analogy to protein A of Staphylococcus aureus.
TMPY-05207	PRKAR1A Protein, Mouse, Recombinant (His) 1300018C22Rik,protein kinase, cAMP-dependent, regul...	Mouse	Baculovirus Insect Cells
	PRKAR1A Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.6 kDa and the accession number is Q9DBC7.
TMPY-03627	CREB3L1 Protein, Human, Recombinant (aa 396-519, His) OASIS,PSEC0238,cAMP responsive element binding prot...	Human	HEK293 Cells
	CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting prol...
TMPJ-00886	ATF1 Protein, Human, Recombinant (His) Cyclic AMP-dependent transcription factor ATF-1,Activating t...	Human	E. coli
	Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It also binds to the ...
TMPY-03656	PRKAR1A Protein, Human, Recombinant (His) PRKAR1,CAR,CNC1,PPNAD1,CNC,protein kinase, cAMP-dep...	Human	HEK293 Cells
	PRKAR1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is P10644.
TMPH-01058	Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO) CAP18,Cathelicidin antimicrobial peptide,CAMP,FALL3...	Human	E. coli
	Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 24.7 kDa and the accession number is P49913.
TMPH-01165	CREB1 Protein, Human, Recombinant (His) CREB-1,cAMP-responsive element-binding protein 1,Cy...	Human	E. coli
	CREB1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02614	CREB5 Protein, Mouse, Recombinant (His) Creb5,Cyclic AMP-responsive element-binding protein 5,cA...	Mouse	E. coli
	Binds to the cAMP response element and activates transcription.
TMPH-01164	ATF-3 Protein, Human, Recombinant (His) ATF3,cAMP-dependent transcription factor ATF-3,Acti...	Human	E. coli
	ATF3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-03274	ATF-4 Protein, Rat, Recombinant (His & Myc) cAMP-dependent transcription factor ATF-4,Activatin...	Rat	E. coli
	ATF-4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is Q9ES19.
TMPH-02613	ATF-5 Protein, Mouse, Recombinant (His & Myc) Transcription factor ATFx,Transcription factor-like protein ...	Mouse	E. coli
	Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcrip...
TMPH-00328	Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His) flaB,Flagellin B	Campylobacter jejuni	E. coli
	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 61.6 kDa and the accession number is Q46114.
TMPH-00327	Flagellin A Protein, Campylobacter jejuni, Recombinant flaA,Flagellin A	Campylobacter jejuni	E. coli
	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin A Protein, Campylobacter jejuni, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 59.5 kDa and the accession number is Q46113.
TMPH-00325	S-layer Protein, Campylobacter fetus, Recombinant (His & Myc) Surface array protein,sapA,S-layer protein	Campylobacter fetus	E. coli
	The S-layer is a paracrystalline mono-layered assembly of proteins which coats the surface of bacteria. This protein is critical for virulence. S-layer Protein, Campylobacter fetus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.0 kDa and the accession number is P35827.
TMPH-02892	SCAMP4 Protein, Mouse, Recombinant (His) Secretory carrier-associated membrane protein 4,Scamp	Mouse	E. coli
	Probably involved in membrane protein trafficking. SCAMP4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.9 kDa and the accession number is Q9JKV5.
TMPH-00326	Flagellin A Protein, Campylobacter jejuni, Recombinant (His) Flagellin A,flaA	Campylobacter jejuni	E. coli
	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin A Protein, Campylobacter jejuni, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 61.5 kDa and the accession number is Q46113.
TMPH-00574	Adenylate cyclase Protein, E. coli, Recombinant (His) cyaA,EC:4.6.1.1,Adenylyl cyclase,ATP pyrophosphate-lyase	E. coli	E. coli
	Catalyzes the formation of the second messenger cAMP from ATP. Its transcript is probably degraded by endoribonuclease LS (rnlA), decreasing cAMP levels and the negative regulator Crp-cAMP, which then induces its own transcription again.
TMPK-00677	PKA/PRKACA Protein, Canine, Recombinant (His) PKA C alpha,PKACA,PPNAD4,PKA C α,PKA C-α,PKA C-alpha,PRKACA	Canine	E. coli
	The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP signaling. As such, PKA is involved in the control of a wide variety of cellular processes including metabolism, cell growth, gene expression and apoptosis. cAMP-dependent PKA signaling pathways play important roles during infection and virulence of various pathogens. Since fluxes in cAMP are involved in multiple intracellular functions, a vari...
TMPJ-00528	PPP1R1A Protein, Human, Recombinant (His) PPP1R1A,I-1,IPP-1,Protein Phosphatase Inhibitor 1,Protein Ph...	Human	E. coli
	Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by cal...
TMPY-02977	PDE1C Protein, Human, Recombinant (His & GST) hCam-3,phosphodiesterase 1C, calmodulin-dependent 70kDa,cam-...	Human	Baculovirus Insect Cells
	PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDEs are expressed ubiquitously, with each subtype having a s...
TMPH-01347	FSHR Protein, Human, Recombinant (E. coli, His) Follicle-stimulating hormone receptor,Follitropin receptor,F...	Human	E. coli
	G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.0 kDa and the accession number is P23945.
TMPH-02685	GPHB5 Protein, Mouse, Recombinant (His & Myc) Glycoprotein hormone beta-5,Thyrostimulin subunit beta,Gphb5	Mouse	E. coli
	Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
TMPH-02143	NR5A1 Protein, Human, Recombinant (His) Adrenal 4-binding protein,NR5A1,Steroidogenic factor 1,Fushi...	Human	E. coli
	Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cA...
TMPH-01348	FSHR Protein, Human, Recombinant (His) Follitropin receptor,FSHR,Follicle-stimulating hormone recep...	Human	HEK293 Cells
	G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 43.5 kDa and the accession number is P23945.
TMPH-00221	Agouti-signaling Protein, Bovine, Recombinant (His) ASP,ASIP,Agouti-signaling protein,Agouti switch protein	Bovine	Baculovirus Insect Cells
	Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). Agouti-signaling Protein, Bovine, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 14.9 kDa and the accession number is Q29414.
TMPH-02684	GPHB5 Protein, Mouse, Recombinant (His) Thyrostimulin subunit beta,Glycoprotein hormone beta-5,Gphb5	Mouse	P. pastoris (Yeast)
	Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. GPHB5 Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 13.3 kDa and the accession number is Q812B2.
TMPH-01677	MBD2 Protein, Human, Recombinant (His & KSI) Methyl-CpG-binding domain protein 2,Methyl-CpG-binding prote...	Human	E. coli
	Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
TMPH-01025	CALCA Protein, Human, Recombinant (GST) Calcitonin gene-related peptide 1,CGRP-I,CALCA,CALC1,Alpha-t...	Human	E. coli
	CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CALCA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 30.6 kDa and the accession number is P06881.
TMPH-02022	RXFP2 Protein, Human, Recombinant (His & Myc) G-protein coupled receptor 106,Relaxin receptor 2,Relaxin fa...	Human	E. coli
	Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). RXFP2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.1 kDa and the accession number is Q8WXD0.
TMPH-01385	GLP1R Protein, Human, Recombinant (His) Glucagon-like peptide 1 receptor,GLP1R	Human	HEK293 Cells
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-02676	GLP1R Protein, Mouse, Recombinant (His & SUMO) Glucagon-like peptide 1 receptor,Glp1r	Mouse	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.4 kDa and the accession number is O35659.
TMPH-01384	GLP1R Protein, Human, Recombinant (E. coli, His) GLP1R,Glucagon-like peptide 1 receptor	Human	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-03301	GLP1R Protein, Rat, Recombinant (E. coli, His) Glp1r,Glucagon-like peptide 1 receptor	Rat	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.1 kDa and the accession number is P32301.
TMPY-02081	PDE2A Protein, Human, Recombinant (aa 215-900, His) phosphodiesterase 2A, cGMP-stimulated,cGSPDE,PED2A4,PDE2A1,C...	Human	Baculovirus Insect Cells
	cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 subfamily. Phosphodiesterases (PDEs) comprise a family of enzymes that regulate the levels of cyclic nucleotides, key second messengers that mediate a diverse array of functions. Phosphodiesterases (PDEs) modulate signaling by cyclic nucleotides in diverse processes such as cardiac ...
TMPH-02219	JUN Protein, Human, Recombinant (His & Myc) Proto-oncogene c-Jun,p39,V-jun avian sarcoma virus 17 oncoge...	Human	E. coli
	Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells. JUN Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system wi...
TMPH-01422	GNAS Protein, Human, Recombinant (His & SUMO) Guanine nucleotide-binding protein G(s) subunit alpha isofor...	Human	E. coli
	Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. GNAS Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6...
TMPH-02218	JUN Protein, Human, Recombinant (His) p39,JUN,Transcription factor Jun,Transcription factor AP-1 s...	Human	Baculovirus Insect Cells
	Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells. JUN Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with C-6x...
TMPJ-01190	SPESP1 Protein, Human, Recombinant (His) Sperm Equatorial Segment Protein 1,Glycosylated 38 kDa Sperm...	Human	HEK293 Cells
	Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may intera...
TMPY-01117	MRAP Protein, Human, Recombinant (hFc) FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,B2...	Human	HEK293 Cells
	MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece...
TMPY-02444	ATF2 Protein, Human, Recombinant (His & GST) CREB2,CRE-BP1,CREB-2,TREB7,activating transcription factor 2...	Human	Baculovirus Insect Cells
	Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has ...
TMPJ-00821	OM Protein, Human, Recombinant (His) Oncomodulin-1,OCM,OM,OCMN,Parvalbumin Beta,Parvalbumin β,OCM...	Human	E. coli
	Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to...
TMPY-01819	PDE1B Protein, Human, Recombinant (His & GST) PDES1B,phosphodiesterase 1B, calmodulin-dependent,PDE1B1	Human	Baculovirus Insect Cells
	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, also known as Cam-PDE 1B and PDE1B, is a cytoplasm protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE1 subfamily. Phosphodiesterase-1A (PDE1A), Phosphodiesterase-1B (PDE1B), Phosphodiesterase-4B (PDE4B), and Phosphodiesterase-4A (PDE4A) are important regulators of signal transduction in striatum due to their catalysis of cyclic AMP and cyclic GMP. PDE1B is highly expressed in the striatum. It b...
TMPY-04468	STK16 Protein, Human, Recombinant (His & NusA) MPSK,serine/threonine kinase 16,TSF1,KRCT,PKL12	Human	E. coli
	Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is ubiquitously expressed at very low levels. STK16 / MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or c...

重组蛋白

PKI-Beta Protein, Human, Recombinant (His)

Cat.No: TMPJ-01309

Species: Human

Expression System: E. coli

CAMP Factor Protein, Cutibacterium acnes, Recombinant (His)

Cat.No: TMPY-06476

Species: Cutibacterium acnes

Expression System: Baculovirus Insect Cells

PRKAR1A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05207

Species: Mouse

Expression System: Baculovirus Insect Cells

CREB3L1 Protein, Human, Recombinant (aa 396-519, His)

Cat.No: TMPY-03627

Species: Human

Expression System: HEK293 Cells

ATF1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00886

Species: Human

Expression System: E. coli

PRKAR1A Protein, Human, Recombinant (His)

Cat.No: TMPY-03656

Species: Human

Expression System: HEK293 Cells

Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-01058

Species: Human

Expression System: E. coli

CREB1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01165

Species: Human

Expression System: E. coli

CREB5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02614

Species: Mouse

Expression System: E. coli

ATF-3 Protein, Human, Recombinant (His)

Cat.No: TMPH-01164

Species: Human

Expression System: E. coli

ATF-4 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03274

Species: Rat

Expression System: E. coli

ATF-5 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02613

Species: Mouse

Expression System: E. coli

Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His)

Cat.No: TMPH-00328

Species: Campylobacter jejuni

Expression System: E. coli

Flagellin A Protein, Campylobacter jejuni, Recombinant

Cat.No: TMPH-00327

Species: Campylobacter jejuni

Expression System: E. coli

S-layer Protein, Campylobacter fetus, Recombinant (His & Myc)

Cat.No: TMPH-00325

Species: Campylobacter fetus

Expression System: E. coli

SCAMP4 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02892

Species: Mouse

Expression System: E. coli

Flagellin A Protein, Campylobacter jejuni, Recombinant (His)

Cat.No: TMPH-00326

Species: Campylobacter jejuni

Expression System: E. coli

Adenylate cyclase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00574

Species: E. coli

Expression System: E. coli

PKA/PRKACA Protein, Canine, Recombinant (His)

Cat.No: TMPK-00677

Species: Canine

Expression System: E. coli

PPP1R1A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00528

Species: Human

Expression System: E. coli

PDE1C Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02977

Species: Human

Expression System: Baculovirus Insect Cells

FSHR Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01347

Species: Human

Expression System: E. coli

GPHB5 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02685

Species: Mouse

Expression System: E. coli

NR5A1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02143

Species: Human

Expression System: E. coli

FSHR Protein, Human, Recombinant (His)

Cat.No: TMPH-01348

Species: Human

Expression System: HEK293 Cells

Agouti-signaling Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00221

Species: Bovine

Expression System: Baculovirus Insect Cells

GPHB5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02684

Species: Mouse

Expression System: P. pastoris (Yeast)

MBD2 Protein, Human, Recombinant (His & KSI)

Cat.No: TMPH-01677

Species: Human

Expression System: E. coli

CALCA Protein, Human, Recombinant (GST)

Cat.No: TMPH-01025

Species: Human

Expression System: E. coli

RXFP2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02022

Species: Human

Expression System: E. coli

GLP1R Protein, Human, Recombinant (His)

Cat.No: TMPH-01385

Species: Human

Expression System: HEK293 Cells

GLP1R Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02676

Species: Mouse

Expression System: E. coli

GLP1R Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01384

Species: Human

Expression System: E. coli

GLP1R Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03301

Species: Rat

Expression System: E. coli

PDE2A Protein, Human, Recombinant (aa 215-900, His)

Cat.No: TMPY-02081

Species: Human

Expression System: Baculovirus Insect Cells

JUN Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02219

Species: Human

Expression System: E. coli

GNAS Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01422

Species: Human

Expression System: E. coli

JUN Protein, Human, Recombinant (His)

Cat.No: TMPH-02218

Species: Human

Expression System: Baculovirus Insect Cells

SPESP1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01190

Species: Human

Expression System: HEK293 Cells

MRAP Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01117

Species: Human

Expression System: HEK293 Cells

ATF2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02444

Species: Human

Expression System: Baculovirus Insect Cells

OM Protein, Human, Recombinant (His)

Cat.No: TMPJ-00821

Species: Human

Expression System: E. coli

PDE1B Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-01819

Species: Human

Expression System: Baculovirus Insect Cells

STK16 Protein, Human, Recombinant (His & NusA)

Cat.No: TMPY-04468

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0337	(24Rac)-Campesterol-d7
	(24Rac)-Campesterol-d7 是 (24Rac)-Campesterol 的氘代化合物。(24Rac)-Campesterol 的 CAS 号为 474-62-4。Campesterol是一种植物甾醇，具有降胆固醇和抗癌的活性。
TMIH-0512	Salbutamol-d3
	Salbutamol-d3 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
TMID-0233	Salbutamol-d9
	Salbutamol-d9 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
T70035	Tasimelteon-d5
	Tasimelteon-d5 is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon is a melatonin (MT) receptor agonist. It selectively binds MT1 and MT2 receptors over a panel of 160 additional receptors and enzymes at 10 µM. Tasimelteon inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of no...
T71141	Fenspiride-d5
	Fenspiride-d5 is intended for use as an internal standard for the quantification of fenspiride by GC- or LC-MS. Fenspiride is an antagonist of histamine H1 receptors and a non-steroidal anti-inflammatory drug (NSAID). It inhibits histamine-induced contraction of isolated guinea pig trachea but not histamine-induced inotropy of isolated guinea pig heart. It also inhibits phosphodiesterase 4 (PDE4), PDE5, and PDE3 (IC50s = 69, ~158, and 363 µM, respectively, in isolated human bronchi derived from ...
TMID-0119	Diprophylline-d6
	Diprophylline-d6 是 Diprophylline 的氘代化合物。Diprophylline 的 CAS 号为 479-18-5。Diphylline 是一种A1/A2腺苷受体拮抗剂，也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物，具有支气管扩张和血管扩张作用，有用于治疗慢性支气管炎和肺气肿的潜力。

同位素标记化合物

(24Rac)-Campesterol-d7

Cat.No: TMIJ-0337

Cat.No: TMIH-0512

Cat.No: TMID-0233

Cat.No: T70035

Cat.No: T71141

Diprophylline-d6

Cat.No: TMID-0119

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