Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T69909 |
CAM4066
|
Others | Others |
CAM4066 is a novel potent and selective CK2alpha inhibitor. | |||
T69908 |
Pidnarulex HCl
|
Others | Others |
Pidnarulex HCl is the salt form of CX-5461, a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhibits rRNA synthesis by Pol I in the nucleolus, but does not inhibit mRNA synthesis by RNA Polymerase II (Pol II) and does not inhibit DNA replication or protein synthesis. Inhibition of Pol I results in nucleolar stress and release of ribosomal proteins (RP) from the nucleolus. T... |