Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02964 |
Calcineurin B/PPP3R1 Protein, Human, Recombinant (His)
protein phosphatase 3, regulatory subunit B, alpha,CNB1<... |
Human | Baculovirus Insect Cells |
PPP3R1 belongs to the calcineurin regulatory subunit family. It is a regulatory subunit of calcineurin. Calcineurin is composed of two subunits: calcineurin A (CnA) and calcineurin B (CnB). Dephosphorylation of the nuclear factor of activated T-cells (NF-AT) by Calcineurin is essential for NF-AT activation, nuclear translocation, and early gene expression in T-cells. PPP3R1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase which takes a vital part in the T cell activatio... |