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Cat. No.	Product Name	Target	Signaling Pathways
T26936	C188 Cpd188,STAT3-IN-C188,Cpd-188,C 188,C-188	Others	Others
	C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect agai
T4650	C188-9 TTI-101	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	C188-9 (TTI-101) 是一种Stat3抑制剂，其Kd 值为 4.7 nM。它诱导 AML 细胞系和原代标本凋亡，抑制原代 AML 细胞集落形成。它抑制 G-CSF 诱导的 STAT3 激活和 STAT3 依赖性基因表达。