Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37454 |
C16 dihydro Ceramide (d18:0/16:0)
N-Palmitoyl Sphinganine,Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,C16 dihydroceramide,Ceramide (d18:0/16:0) |
Others | Others |
C16 dihydro Ceramide (d18:0/16:0) (Cer(d18:0/16:0)) 是合成神经酰胺的前体,诱导核周区域自噬,可用于研究细胞膜的稳定性和神经系统疾病。 | |||
T85052 |
C16 1-Deoxyceramide (m18:1/16:0)
C16:0 Ceramide (m18:1/16:0),Cer(m18:1/16:0),C16:0 1-Deoxyceramide,N-Hexadecanoyl-1-deoxy-4,5-dihydro-Sphingosine |
Others | Others |
T85175 |
C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0)
N-(R,S)-α-hydroxyhexadecanoyl-D-erythro-Dihydrosphingosine,(±)-2'-hydroxy Ceramide (d18:0/16:0) |
Others | Others |
T36468 |
ARN14988
|
Others | Others |
ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells (EC50s = 41.8 and 67.7 μM, respectively). |