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Search Results for " c16 ceramide "

Targets Recommended: p53

12

抑制剂 & 化合物

1

天然产物

2

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T37562	C16 Ceramide N-acylsphingosine,C16 Ceramide (d18:1/16:0),Palmitoyl Ceramide,N-Palmitoylsphingosine	p53	Apoptosis
	C16 Ceramide (Palmitoyl Ceramide) 是一种天然小分子，通过直接选择性结合激活 p53。
T85197	C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium salt) CerP(d18:1/16:0),C16 Ceramide-1-phosphate,Ceramide-1-phosphate (d18:1/16:0),C16 C1P	Others	Others

T69361	C16-Urea-Ceramide	Others	Others
	C16-Urea-Ceramide s a neutral ceramidase (nCDase) inhibitor. It is a bioactive ceramide.
T85284	C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) N-(2'-(S)-hydroxypalmitoyl)-D-erythro-Sphingosine,2'(S)-hydroxy Cer(d18:1/16:0),2'-hydroxy C16-Ceramide,(2'(S)-hydroxy) Ceramide (d18:1/16:0),16:0 (2S-OH)-Ceramide	Others	Others

T37454	C16 dihydro Ceramide (d18:0/16:0) N-Palmitoyl Sphinganine,Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,C16 dihydroceramide,Ceramide (d18:0/16:0)	Others	Others
	C16 dihydro Ceramide (d18:0/16:0) (Cer(d18:0/16:0)) 是合成神经酰胺的前体，诱导核周区域自噬，可用于研究细胞膜的稳定性和神经系统疾病。
T74304	C16 PEG-Ceramide	Others	Others
	C16 PEG-Ceramide为一种聚乙二醇化神经酰胺，具备脂质载体传递功能，并能诱导自噬(autophagy)，在癌症研究中有应用。
T85052	C16 1-Deoxyceramide (m18:1/16:0) C16:0 Ceramide (m18:1/16:0),Cer(m18:1/16:0),C16:0 1-Deoxyceramide,N-Hexadecanoyl-1-deoxy-4,5-dihydro-Sphingosine	Others	Others

T85175	C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0) N-(R,S)-α-hydroxyhexadecanoyl-D-erythro-Dihydrosphingosine,(±)-2'-hydroxy Ceramide (d18:0/16:0)	Others	Others

T37563	C22 Ceramide (d18:1/22:0) Cer(d18:1/22:0),C22 Ceramide,Ceramide (d18:1/22:0)
	C22 Ceramide (d18:1/22:0) (C22 Ceramide) 是一种从海绵Haliclona koremella 中分离出含有山嵛酸的长链神经酰胺，是一种内源性生物活性鞘脂。C22 Ceramide (d18:1/22:0) 可特异性抑制MCSR，降低离体大鼠肝线粒体和脂质体中 C16-神经酰胺通道的形成。
T37872	C16 Galactosylceramide (d18:1/16:0) C16 Galactosylceramide (d18:1/16:0)	Others	Others
	C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid .
T36468	ARN14988	Others	Others
	ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells (EC50s = 41.8 and 67.7 μM, respectively).
T36321	C6 Urea Ceramide	Others	Others
	C6 urea ceramide is an inhibitor of neutral ceramidase.1 It increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and in HT-29 colon cancer cells but not in MEFs lacking neutral ceramidase. It inhibits proliferation of, and induces apoptosis and autophagy in HT-29, but not non-cancerous RIE-1, cells when used at concentrations of 5 and 10 μM. C6 urea ceramide decreases total β-catenin, increases phosphorylated β-catenin, and induces colocalization of β-catenin with the ...

化合物

C16 Ceramide

Cat.No: T37562

Synonym: N-acylsphingosine,C16 Ceramide (d18:1/16:0),Palmitoyl Ceramide,N-Palmitoylsphingosine

Target: p53

C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium salt)

Cat.No: T85197

Synonym: CerP(d18:1/16:0),C16 Ceramide-1-phosphate,Ceramide-1-phosphate (d18:1/16:0),C16 C1P

Target: Others

C16-Urea-Ceramide

Cat.No: T69361

Target: Others

C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0)

Cat.No: T85284

Synonym: N-(2'-(S)-hydroxypalmitoyl)-D-erythro-Sphingosine,2'(S)-hydroxy Cer(d18:1/16:0),2'-hydroxy C16-Ceramide,(2'(S)-hydroxy) Ceramide (d18:1/16:0),16:0 (2S-OH)-Ceramide

Target: Others

C16 dihydro Ceramide (d18:0/16:0)

Cat.No: T37454

Synonym: N-Palmitoyl Sphinganine,Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,C16 dihydroceramide,Ceramide (d18:0/16:0)

Target: Others

C16 PEG-Ceramide

Cat.No: T74304

Target: Others

C16 1-Deoxyceramide (m18:1/16:0)

Cat.No: T85052

Synonym: C16:0 Ceramide (m18:1/16:0),Cer(m18:1/16:0),C16:0 1-Deoxyceramide,N-Hexadecanoyl-1-deoxy-4,5-dihydro-Sphingosine

Target: Others

C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0)

Cat.No: T85175

Synonym: N-(R,S)-α-hydroxyhexadecanoyl-D-erythro-Dihydrosphingosine,(±)-2'-hydroxy Ceramide (d18:0/16:0)

Target: Others

C22 Ceramide (d18:1/22:0)

Cat.No: T37563

Synonym: Cer(d18:1/22:0),C22 Ceramide,Ceramide (d18:1/22:0)

C16 Galactosylceramide (d18:1/16:0)

Cat.No: T37872

Synonym: C16 Galactosylceramide (d18:1/16:0)

Target: Others

Cat.No: T36468

Target: Others

C6 Urea Ceramide

Cat.No: T36321

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T82572	D-Glucosyl-β-1,1′-N-palmitoylsphingosine C16 Glucosyl(β) Ceramide (d18:1/16:0)	Others	Others
	D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl(β) Ceramide (d18:1/16:0)) 是内源性Mincle配体，具免疫刺激活性。

天然产物

D-Glucosyl-β-1,1′-N-palmitoylsphingosine

Cat.No: T82572

Synonym: C16 Glucosyl(β) Ceramide (d18:1/16:0)

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0131	C16 Ceramide-d7
	C16 Ceramide-d7 是 C16 Ceramide 的氘代化合物。
T36149	13C C16 Sphingomyelin (d18:1/16:0)
	13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. It is intended for use as an internal standard for the quantification of C16 sphingomyelin by GC- or LC-MS. C16 Sphingomyelin is a form of sphingomyelin containing palmitate (16:0) at the variable acylation position. It is the most common form of sphingomyelin found in eggs and is less abundant in the brain and in milk. C16 Sphingomyelin interacts with cholesterol in or...

同位素标记化合物

C16 Ceramide-d7

Cat.No: TMIH-0131

13C C16 Sphingomyelin (d18:1/16:0)

Cat.No: T36149

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