Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70008 |
Bomedemstat ditosylate
MK-3543 ditosylate,IMG-7289 ditosylate |
Apoptosis; Histone Demethylase | Apoptosis; Chromatin/Epigenetic |
Bomedemstat ditosylate (IMG-7289 ditosylate) 是一种具有口服活性的 lysine-specific demethylase 1 (LSD1) 抑制剂,具有抗肿瘤活性,增强 SCLC 同基因模型中对 PD-1 抑制的反应,抑制癌细胞增殖,诱导细胞凋亡。Bomedemstat ditosylate 可用于研究骨髓增生性肿瘤和骨髓纤维化。 | |||
T70007 |
CT-179
|
Others | Others |
CT-179 is a highly potent and selective small molecule inhibitor of Olig2 with excellent drug-like properties. |