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Search Results for " bilirubin "

Targets Recommended: Others

7

抑制剂 & 化合物

2

天然产物

6

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T35980	Bilirubin Conjugate (sodium salt)	Others	Others
	Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives. In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and conjugated to one or two glucuronic acids in a reaction catalyzed by UDP glucuronidase to form bilirubin mono or diglucuronide. This water-soluble form is then excreted from the liver in bile in the feces or is converted to urobilinogen and excreted in the urine. In addition to ...
T76141	Bilirubin oxidase	Others	Others
	Bilirubin oxidase (BOD) 为一多铜氧化酶，能催化胆红素氧化为胆绿素，同时将分子氧还原成水。该酶在卟啉及叶绿素代谢中起作用，并作为氧还原催化剂在生化研究中广泛应用。
T32951	Lumirubin	Others	Others
	Lumirubin is a water-soluble photoproduct of bilirubin formed in vivo during phototherapy.
T84736	Biliverdin NSC 62793	Others	Others
	胆绿素是通过胆红素氧化得到的化合物，可经由谷氨酸棒杆菌的非原卟啉途径进行合成。
T84996	6-hydroxy Etodolac	Others	Others
	6-Hydroxy Etodolac, a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac, causes false positives in diazo diagnostic tests for urinary bilirubin.
T73899	Uridine diphosphate glucuronic acid ammonium	Others	Others
	Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium 是一种由 UDP-葡萄糖脱氢酶催化生成的辅助因子，属于糖核苷酸生物合成的关键前体。它不仅是 C4 表聚酶和脱羧酶释放 UDP-半乳糖醛酸(UDP-GalA)和 UDP-戊糖产物的共同底物，而且作为葡萄糖醛酸供体，在胆红素在内质直肠结合的研究中有重要应用。
T36864	GRP (human) (trifluoroacetate salt)
	Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM. In vivo, GRP (0.35 nmol/kg/h) increases both pancreatic exocrine secretion and pancreatic polypeptide (PP) release in rats. It dose-depend...

化合物

Bilirubin Conjugate (sodium salt)

Cat.No: T35980

Target: Others

Bilirubin oxidase

Cat.No: T76141

Target: Others

Cat.No: T32951

Target: Others

Cat.No: T84736

Synonym: NSC 62793

Target: Others

6-hydroxy Etodolac

Cat.No: T84996

Target: Others

Uridine diphosphate glucuronic acid ammonium

Cat.No: T73899

Target: Others

GRP (human) (trifluoroacetate salt)

Cat.No: T36864

Cat. No.	Product Name	Target	Signaling Pathways
T2934	Bilirubin 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin	Endogenous Metabolite	Metabolism
	Bilirubin (Principal bile pigment) 是血红素分解代谢产生的黄色产物，是肝功能的重要指标。Bilirubin 具有抗诱变和抗氧化作用。
T35981	Biliverdin hydrochloride	Antioxidant	oxidation-reduction
	Biliverdin hydrochloride 是一种由血红素氧化形成的四吡咯水溶性化合物，具有潜在的抗氧化活性，参与胆绿素-胆红素氧化还原系统。

天然产物

Cat.No: T2934

Synonym: 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin

Target: Endogenous Metabolite

Biliverdin hydrochloride

Cat.No: T35981

Target: Antioxidant

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01009	BLVRA Protein, Human, Recombinant (His) Biliverdin reductase A,BVR,BVR A,BLVR,BLVRA,Biliverdin-IX α-...	Human	E. coli
	Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily. BLVRA is an enzyme that in humans is encoded by the BLVRA gene. BLVRA plays an important role in reducing the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. BLVRA acts on biliverdin by reducing its double-bond between the pyrrole rings into a single-bond. It accomplishes this using NADPH + H+ ...
TMPH-01432	HMOX1 Protein, Human, Recombinant (His) HMOX1,Heme oxygenase 1	Human	E. coli
	Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. HMOX1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHi...
TMPY-02519	BLVRB Protein, Human, Recombinant (His) HEL-S-10,biliverdin reductase B,FLR,BVRB,SDR43U1	Human	E. coli
	Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step i...
TMPJ-00817	HO-1 Protein, Human, Recombinant HO,HMOX1,HO-1,Heme Oxygenase 1,HO1	Human	E. coli
	Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy me...
TMPY-01878	L-FABP Protein, Human, Recombinant (His) fatty acid binding protein 1, liver,FABPL,L-FABP	Human	E. coli
	Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is t...
TMPJ-00758	AFP Protein, Mouse, Recombinant (His) Alpha-fetoprotein,α-fetoglobulin,Alpha-1-fetoprotein,Afp,α-1...	Mouse	HEK293 Cells
	Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitaminD (Gc) protein, and alpha-albumin. AFP is a major plasma protein produced by the yolk sac and the liver during fetal development. It is thought to be the fetal form of serum albumin. AFP binds to copper, nickel, fatty acids and bilirubin and is found in monomeric, dimeric and trimeric forms. AFP is one of the several embryo-specific proteins and is adominant serum protein as ea...

重组蛋白

BLVRA Protein, Human, Recombinant (His)

Cat.No: TMPJ-01009

Species: Human

Expression System: E. coli

HMOX1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01432

Species: Human

Expression System: E. coli

BLVRB Protein, Human, Recombinant (His)

Cat.No: TMPY-02519

Species: Human

Expression System: E. coli

HO-1 Protein, Human, Recombinant

Cat.No: TMPJ-00817

Species: Human

Expression System: E. coli

L-FABP Protein, Human, Recombinant (His)

Cat.No: TMPY-01878

Species: Human

Expression System: E. coli

AFP Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00758

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T36055	Nitisinone-13C6 Nitisinone-13C6
	Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...

同位素标记化合物

Nitisinone-13C6

Cat.No: T36055

Synonym: Nitisinone-13C6

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