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Search Results for " beta-amyloid "

Targets Recommended: Beta Amyloid

83

抑制剂 & 化合物

5

天然产物

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化合物库

28

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L1310	细胞骨架化合物库		759 compounds
	759 种细胞骨架相关的化合物，可以用于高通量和高内涵筛选；

化合物库

细胞骨架化合物库

Cat.No: L1310

Compounds: 759

Cat. No.	Product Name	Target	Signaling Pathways
TP1214L	β-Amyloid 15-21 acetate Beta-Amyloid (15-21) acetate	Beta Amyloid	Neuroscience
	β-Amyloid 15-21 acetate (Beta-Amyloid(15-21) acetate) 是 Amyloid-β 肽的片段，可用于神经系统疾病的研究。该片段参与β折叠形成。
TP1229	β-Amyloid (1-15) Amyloid β-Protein (1-15)	Beta Amyloid	Neuroscience
	β-Amyloid (1-15) (Amyloid β-Protein (1-15)) 是 β-淀粉样蛋白片段，可用于研究阿尔茨海默病。
T14284	β-Amyloid (25-35) β-Amyloid peptide(25-35),Aβ25-35,BETA-淀粉样蛋白片断25-35,Amyloid beta-peptide(25-35)	Beta Amyloid	Neuroscience
	β-Amyloid (25-35) (Aβ25-35) 是一种阿尔茨海默氏淀粉样蛋白β肽的Aβ(25-35) 片段，在培养细胞中显示出神经毒性作用。
T7562	β-Amyloid (31-35) 异亮氨酰-异亮氨酰-甘氨酰-亮氨酰-蛋氨酸,β-Amyloid 31-35(TFA),β-Amyloid 31-35	Beta Amyloid	Neuroscience
	β-Amyloid (31-35) (β-Amyloid 31-35) 是一种天然 Amyloid-β 肽的最短序列，具有神经毒性。
T7680	GSNKGAIIGLM(131602-53-4(free base)) Amyloid beta-peptide(25-35),BETA-淀粉样蛋白片断25-35	Beta Amyloid	Neuroscience
	GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) 是阿尔茨海默病淀粉样蛋白 β-肽的片段 Aβ(25-35)。
T35499	β-Amyloid (1-42), (rat/mouse) (TFA) Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA
	β-Amyloid (1-42), (rat/mouse) (TFA) 是由 42 个氨基酸组成的多肽片段，可用于研究阿尔茨海默症。
TP1359L	Amyloid β Peptide (42-1)(human) acetate Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)	Beta Amyloid	Neuroscience
	Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽，其在阿尔茨海默病的发病机制中起关键作用。
TP1733	Beta-Amyloid(1-14),mouse,rat
	Beta-Amyloid(1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. This peptide is amino acids 1 to 14 fragment of Beta-Amyloid peptide.
TP1786L	Amyloid β-Protein 10-20 acetate Amyloid β-Protein 10-20 acetate(152286-31-2 free base)	Beta Amyloid	Neuroscience
	Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) 是 Amyloid-β 肽的片段，可能用于神经系统疾病的研究。Amyloid β 蛋白片段含有 α-分泌酶加工位点（Lys16-Leu17 键）。它还包含负责与小胶质细胞结合的 HHQK 结构域（残基 13-16）。
T32106	Human beta-amyloid protein 42 (1-7) Vanutide	Others	Others
	Human beta-amyloid protein 42 (1-7) is a bioactive chemical.
TP1866L	β-amyloid 1-11 acetate(190436-05-6 free base)	Beta Amyloid	Neuroscience
	β-amyloid 1-11 acetate(190436-05-6 free base) 是 Amyloid-β 肽的片段，可用于神经系统疾病的研究。
T4398	LX2343	Beta Amyloid; Beta-Secretase; BACE; PI3K; Autophagy	Autophagy; Neuroscience; PI3K/Akt/mTOR signaling
	LX2343 是一种非 ATP 竞争性 PI3K 抑制剂，IC50 为 15.99±3.23 μM。它是一种 BACE1 酶抑制剂，IC50 值为 11.43±0.36 μM。它在促进 Aβ 清除中刺激自噬。
T6562	Latrepirdine dihydrochloride Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin	Beta Amyloid; 5-HT Receptor; Adrenergic Receptor; GluR; Autophagy; Histamine Receptor	Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Latrepirdine dihydrochloride (Dimebolin dihydrochloride) 是一种具有口服活性和神经活性的多种药物靶点的拮抗剂，可刺激淀粉样前体蛋白分解代谢和 β-淀粉样蛋白分泌。
TP1214	β-Amyloid 15-21 Beta-Amyloid (15-21)
	β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation.
TP1231	β-Amyloid (29-40) Amyloid beta-protein(29-40),β-Amyloid 29-40
	β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusion of liposomes can be induced by th
TP1227	β-Amyloid (12-28) β-amyloid 12-28,Amyloid β-Protein (12-28)
	Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo.
TP1645	β-Amyloid (1-9) β-Amyloid 1-9
	This is an N-terminal fragment of beta amyloid. It consists of amino acid residues 1 to 9. Truncated beta amyloid peptide (10-40) still forms amyloid fibrils and shows fibril polymorphism.
TP1544	β-Amyloid (22-40) β-Amyloid 22-40
	This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein. This peptide sequence is often used in beta amyloid structure and aggregation studies.
TP1538	β-Amyloid (1-20) β-Amyloid 1-20
	This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.
TP1599	β-Amyloid (1-34) β-Amyloid 1-34
	This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.
TP1633	β-Amyloid (18-28) β-Amyloid 18-28
	Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice. These peptides have only amino acid residues VFF at position 18 to 20 in common, suggesting the amnestic effect of the triad.
TP1225	β-Amyloid (22-35) β-Amyloid 22-35,Amyloid β-Protein (22-35)
	β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.
TP1303	β-Amyloid (1-40) β-Amyloid 1-40
	Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.
TP1228	β-Amyloid (1-16) Amyloid β-Protein (1-16),β-Amyloid 1-16
	β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is responsible for the formation of amyloid plaques in the brains of individuals affected by Alzheimer's disease (AD).
TP1494	β-Amyloid (4-10) β-Amyloid 4-10
	Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in mice. This peptide does not elicit an inflammatory response.
TP1719	β-Amyloid (33-40) β-Amyloid 33-40
	β-Amyloid (33-40) is a peptide consisting of amino acid of 33 to 40 of beta amyloid protein.
TP1586	β-Amyloid (35-42) β-Amyloid 35-42
	β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.
TP1500	β-Amyloid (1-17) β-Amyloid 1-17
	This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
TP1673	β-Amyloid (11-22) β-Amyloid 11-22
	β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). AD is the most common neurodegenerat
TP1226	β-Amyloid (1-28) Amyloid β-Protein (1-28),β-Amyloid 1-28
	β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.
TP1692	β-Amyloid (13-27) β-Amyloid 13-27
	β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta amyloid formation.
TP1866	β-Amyloid (1-11) β-amyloid 1-11
	Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid of Alzheimer’s disease patients.
TP1480	β-Amyloid (12-20) β-Amyloid 12-20
	β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has amnestic effects.
TP1786	β-Amyloid (10-20) Amyloid β-Protein 10-20
	Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains the HHQK domain (residues 13-16) re
TP1230	β-Amyloid (1-42), (rat/mouse) β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat)
	Amyloid (1-42), rat is a polypeptide composed of 42 amino acids. It is toxic to hippocampal slices and can be used in the study of alzheimer's disease.
T39285	Biotin-β-Amyloid (1-40)
	Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid- -(1-40) peptide.
T38149	β-Amyloid (1-43)(human)
	The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor of the ubiquitin-dependent protein degradation in vitro.
T37768	β-Amyloid (1-37) (human)
	β-Amyloid (1-37) (human) 与阿尔茨海默病的精神状态有潜在关联。
TP2171	β-amyloid (12-28) (TFA) (107015-83-8 free base) Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA)	Others	Others
	β-amyloid (12-28) TFA, a peptide fragment of β-amyloid protein (β1-42), is the major component of senile plaque cores. β-amyloid (12-28) has aggregation properties and the potential for Alzheimer’s disease research.
T7644	DPN Diarylpropionitrile,2,3-双(4-羟苯基)丙腈	Apoptosis; Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones
	DPN (Diarylpropionitrile) 是一种非甾体雌激素受体 ERβ选择性配体，其 EC50值为 0.85 nM。DPN 在许多神经系统疾病具有神经保护作用。
TP1359	β-Amyloid (42-1), human Amyloid β Peptide (42-1)(human)
	β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42) which plays a key role in the pathogenesis of Alzheimer disease.
TP1441	β-Amyloid (1-40) (rat) Amyloid β-peptide (1-40) rat,β淀粉样肽(1-40)(鼠)
	Rat form of the beta-Amyloid (1-40) peptide
TP1729	β-Amyloid (10-35), amide
	β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide. It serves as the primary constituent of amyloid plaques found in Alzheimer's disease.
T37368	Amyloid-β (1-8) Peptide	Others	Others
	Amyloid-β (1-8) is a wild-type control for the mutation-containing amyloid-β (1-8, A2V) peptide .
TP1007	β-Amyloid (1-42), human 大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human	Beta Amyloid	Neuroscience
	β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽，在阿尔茨海默病的发病机制中起关键作用。
T35498	β-Amyloid (1-14),mouse,rat
	β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. β-Amyloid (1-14),mouse,rat accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer’s disease, which is the most common form of dementia associated with plaques and tangles in the brain[1]. [1]. Chen GF, et al. Amyloid beta: stru...
T39302	β-Amyloid (1-38), mouse, rat
	β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide. Notably, it serves as the primary constituent of amyloid plaques associated with Alzheimer's disease.
T39146	β-Amyloid (1-40), FAM-labeled
	β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λ ex = 492 nm and λ em = 518 nm).
T37367	Amyloid-β (1-42) Peptide (trifluoroacetate salt)	Others	Others
	Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease.1,2,3Aggregation of Aβ42 results in the formation of neurotoxic fibrils or globular oligomers.1Aβ42 accumulates in the brain of many transgenic mouse models of Alzheimer's disease and, in many models, the onset of amyloid deposition positively correlates with deficits in spatial learning and memory.4 1.Wolfe, M.S.Therapeutic strategi...
T37370	Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
	Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM....

化合物

β-Amyloid 15-21 acetate

Cat.No: TP1214L

Synonym: Beta-Amyloid (15-21) acetate

Target: Beta Amyloid

β-Amyloid (1-15)

Cat.No: TP1229

Synonym: Amyloid β-Protein (1-15)

Target: Beta Amyloid

β-Amyloid (25-35)

Cat.No: T14284

Synonym: β-Amyloid peptide(25-35),Aβ25-35,BETA-淀粉样蛋白片断25-35,Amyloid beta-peptide(25-35)

Target: Beta Amyloid

β-Amyloid (31-35)

Cat.No: T7562

Synonym: 异亮氨酰-异亮氨酰-甘氨酰-亮氨酰-蛋氨酸,β-Amyloid 31-35(TFA),β-Amyloid 31-35

Target: Beta Amyloid

GSNKGAIIGLM(131602-53-4(free base))

Cat.No: T7680

Synonym: Amyloid beta-peptide(25-35),BETA-淀粉样蛋白片断25-35

Target: Beta Amyloid

β-Amyloid (1-42), (rat/mouse) (TFA)

Cat.No: T35499

Synonym: Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA

Amyloid β Peptide (42-1)(human) acetate

Cat.No: TP1359L

Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Target: Beta Amyloid

Beta-Amyloid(1-14),mouse,rat

Cat.No: TP1733

Amyloid β-Protein 10-20 acetate

Cat.No: TP1786L

Synonym: Amyloid β-Protein 10-20 acetate(152286-31-2 free base)

Target: Beta Amyloid

Human beta-amyloid protein 42 (1-7)

Cat.No: T32106

Synonym: Vanutide

Target: Others

β-amyloid 1-11 acetate(190436-05-6 free base)

Cat.No: TP1866L

Target: Beta Amyloid

Cat.No: T4398

Target: Beta Amyloid, Beta-Secretase, BACE, PI3K, Autophagy

Latrepirdine dihydrochloride

Cat.No: T6562

Synonym: Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin

Target: Beta Amyloid, 5-HT Receptor, Adrenergic Receptor, GluR, Autophagy, Histamine Receptor

β-Amyloid 15-21

Cat.No: TP1214

Synonym: Beta-Amyloid (15-21)

β-Amyloid (29-40)

Cat.No: TP1231

Synonym: Amyloid beta-protein(29-40),β-Amyloid 29-40

β-Amyloid (12-28)

Cat.No: TP1227

Synonym: β-amyloid 12-28,Amyloid β-Protein (12-28)

β-Amyloid (1-9)

Cat.No: TP1645

Synonym: β-Amyloid 1-9

β-Amyloid (22-40)

Cat.No: TP1544

Synonym: β-Amyloid 22-40

β-Amyloid (1-20)

Cat.No: TP1538

Synonym: β-Amyloid 1-20

β-Amyloid (1-34)

Cat.No: TP1599

Synonym: β-Amyloid 1-34

β-Amyloid (18-28)

Cat.No: TP1633

Synonym: β-Amyloid 18-28

β-Amyloid (22-35)

Cat.No: TP1225

Synonym: β-Amyloid 22-35,Amyloid β-Protein (22-35)

β-Amyloid (1-40)

Cat.No: TP1303

Synonym: β-Amyloid 1-40

β-Amyloid (1-16)

Cat.No: TP1228

Synonym: Amyloid β-Protein (1-16),β-Amyloid 1-16

β-Amyloid (4-10)

Cat.No: TP1494

Synonym: β-Amyloid 4-10

β-Amyloid (33-40)

Cat.No: TP1719

Synonym: β-Amyloid 33-40

β-Amyloid (35-42)

Cat.No: TP1586

Synonym: β-Amyloid 35-42

β-Amyloid (1-17)

Cat.No: TP1500

Synonym: β-Amyloid 1-17

β-Amyloid (11-22)

Cat.No: TP1673

Synonym: β-Amyloid 11-22

β-Amyloid (1-28)

Cat.No: TP1226

Synonym: Amyloid β-Protein (1-28),β-Amyloid 1-28

β-Amyloid (13-27)

Cat.No: TP1692

Synonym: β-Amyloid 13-27

β-Amyloid (1-11)

Cat.No: TP1866

Synonym: β-amyloid 1-11

β-Amyloid (12-20)

Cat.No: TP1480

Synonym: β-Amyloid 12-20

β-Amyloid (10-20)

Cat.No: TP1786

Synonym: Amyloid β-Protein 10-20

β-Amyloid (1-42), (rat/mouse)

Cat.No: TP1230

Synonym: β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat)

Biotin-β-Amyloid (1-40)

Cat.No: T39285

β-Amyloid (1-43)(human)

Cat.No: T38149

β-Amyloid (1-37) (human)

Cat.No: T37768

β-amyloid (12-28) (TFA) (107015-83-8 free base)

Cat.No: TP2171

Synonym: Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA)

Target: Others

Cat.No: T7644

Synonym: Diarylpropionitrile,2,3-双(4-羟苯基)丙腈

Target: Apoptosis, Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Autophagy

β-Amyloid (42-1), human

Cat.No: TP1359

Synonym: Amyloid β Peptide (42-1)(human)

β-Amyloid (1-40) (rat)

Cat.No: TP1441

Synonym: Amyloid β-peptide (1-40) rat,β淀粉样肽(1-40)(鼠)

β-Amyloid (10-35), amide

Cat.No: TP1729

Amyloid-β (1-8) Peptide

Cat.No: T37368

Target: Others

β-Amyloid (1-42), human

Cat.No: TP1007

Synonym: 大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human

Target: Beta Amyloid

β-Amyloid (1-14),mouse,rat

Cat.No: T35498

β-Amyloid (1-38), mouse, rat

Cat.No: T39302

β-Amyloid (1-40), FAM-labeled

Cat.No: T39146

Amyloid-β (1-42) Peptide (trifluoroacetate salt)

Cat.No: T37367

Target: Others

Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)

Cat.No: T37370

Cat. No.	Product Name	Target	Signaling Pathways
TN1736	Hibifolin 棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷	Adenosine deaminase	Metabolism
	Hibifolin 是一种黄酮醇糖苷，是潜在的腺苷脱氨酶抑制剂。它可以保护神经元免受 beta-淀粉样蛋白诱导的毒性。
TN1038	Galgravin	Apoptosis	Apoptosis
	Galgravin 是望春花中的一种天然产物，具有抗炎和体外细胞毒活性，能诱导白血病细胞凋亡。
T32614	L-Clausenamide (-)-Clausenamide	Microtubule Associated	Cytoskeletal Signaling
	L-Clausenamide 是从黄皮 (Clausena lansium (Lour) skeels) 的树叶中提取出来的生物碱，可用于提高认知功能。L-Clausenamide 对β-淀粉样蛋白 (Aβ) 毒性有抑制作用，通过抑制 tau 蛋白磷酸化阻止神经纤维缠结的形成。L-Clausenamide 具有神经保护活性，可用于调节 Aβ25-35 引发的刺激。L-Clausenamide 可用于研究阿尔兹海默症类的神经系统疾病。
T3914	Saikosaponin C 柴胡皂苷C,柴胡皂苷 C	Beta Amyloid; Caspase	Apoptosis; Neuroscience; Proteases/Proteasome
	Saikosaponin C 是一种柴胡中的活性成分，能够抑制 Aβ1-40 和 Aβ1-42 的释放，抑制异常 tau 蛋白的磷酸化，但对 BACE1 的活性和表达无作用。它在阿尔滋海默症中主要靶作用于amyloid beta 和tau 蛋白。
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。

天然产物

Cat.No: TN1736

Synonym: 棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷

Target: Adenosine deaminase

Cat.No: TN1038

Target: Apoptosis

Cat.No: T32614

Synonym: (-)-Clausenamide

Target: Microtubule Associated

Cat.No: T3914

Synonym: 柴胡皂苷C,柴胡皂苷 C

Target: Beta Amyloid, Caspase

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02110	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) AD1,ABPP,CTFγ,APPI,ABETA,β-amyloid 40/β-AP...	Human	E. coli
	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 31.8 kDa and the accession number is P05067-1.
TMPY-02221	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) CVAP,PN2,amyloid β (A4) precursor protein,Aβ,CTFγ,β...	Human	E. coli
	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.4 kDa and the accession number is P05067-1.
TMPY-03884	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) CTFgamma,PN-II,AAA,Aβ,PN2,APPI,AD1,amyloid beta...	Human	E. coli
	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.2 kDa and the accession number is P05067-1.
TMPY-03885	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) AD1,AAA,ABETA,CVAP,PN-II,CTFgamma,Aβ,APPI,PN2,CTFγ,...	Human	E. coli
	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.1 kDa and the accession number is P05067-1.
TMPY-04693	APLP1 Protein, Mouse, Recombinant (His) amyloid β (A4) precursor-like protein 1,amyloid...	Mouse	HEK293 Cells
	APLP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.4 kDa and the accession number is Q03157.
TMPY-03628	APLP1 Protein, Human, Recombinant (His) amyloid beta (A4) precursor-like protein 1...	Human	HEK293 Cells
	APLP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.9 kDa and the accession number is P51693-1.
TMPJ-00684	SNCA Protein, Mouse, Recombinant (His) Snca,Non-A β component of AD amyloid,Non-A4 compone...	Mouse	E. coli
	Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease. Manyneurodegenerative diseases has shown that alpha-synuclein accumulates in dystrophic neurites and in Lewy bodies. The function of alpha-synuclein is closely correlated with its three-dimensional structure, especially for proteins important...
TMPJ-00683	SNCA Protein, Mouse, Recombinant NACP,α-synuclein,Non-A beta component of AD amy...	Mouse	E. coli
	SNCA Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is O55042.
TMPJ-00023	SNCA Protein, Human, Recombinant (His) α-Synuclein,Alpha-Synuclein,PARK1,Non-A β Component of AD	Human	E. coli
	SNCA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P37840.
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc) CTFγ,amyloid beta (A4) precursor protein,A...	Human	HEK293 Cells
	APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPJ-00338	LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated Leucine-rich repeat-containing protein 15,LIB,LRRC15,Leucine...	Human	HEK293 Cells
	The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions used for molecular recognition process such as cell adhesion, signal transduction, DNA repair, and RNA processing. The LRRC15 is also a transmembrane protein demonstrated to play important roles in cancer. LRRC15 expression was notably increased 4.6-fold in cariesdiseased pulpal t...
TMPH-01863	PIEZO1 Protein, Human, Recombinant (His & Myc) Protein FAM38A,Membrane protein induced by beta-	Human	E. coli
	PIEZO1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.6 kDa and the accession number is Q92508.
TMPH-00928	APBA2 Protein, Human, Recombinant (E. coli, His & Myc) Neuronal Munc18-1-interacting protein 2 (Mint-2),Amyloid...	Human	E. coli
	APBA2 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli.
TMPH-00929	APBA2 Protein, Human, Recombinant (His & Myc) Adapter protein X11beta,MINT2,Neuronal Munc18-1-int...	Human	HEK293 Cells
	Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. APBA2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 87.5 kDa and the accession number is Q99767.
TMPJ-00722	APBA3 Protein, Human, Recombinant (His) Neuronal Munc18-1-Interacting Protein 3,Neuron-Specific X11L...	Human	E. coli
	Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amylo...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST) v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPJ-00782	Amyloid Precursor Protein, Human, Recombinant (hFc) Amyloid Precursor,Amyloid Precursor Protei...	Human	HEK293 Cells
	Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective process...
TMPH-02778	Mcpt4 Protein, Mouse, Recombinant (E. coli, His) MSMCP,Mast cell protease 4,Myonase,Serosal mast cell proteas...	Mouse	E. coli
	Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-\|-Ile-5' bond of angiotensin I and the 'Phe-20-\|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-\|-His-9' bond of angiotensin I and the 'Phe-4-\|-Ala-5' and 'Tyr-10-\|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Mcpt4 Protein, Mouse, Recombinant (E. c...
TMPH-03328	Mcpt1 Protein, Rat, Recombinant (Myc) Mast cell protease I,Mcpt1,Chymase,Mast cell protease 1,Chym...	Rat	E. coli
	Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein which ultimately aggregates into amyloid-beta deposits. Mcpt1 Protein, Rat, Recombinant (Myc) is expressed in E. coli expression system with N-Myc tag. The predicted molecular weight is 28.6 kDa and the accession number is P09650.
TMPK-00507	TREM2 Protein, Cynomolgus, Recombinant (His) TREM2,Trem2a,PLOSL2,TREM-2,Trem2c,Trem2b	Cynomolgus	HEK293 Cells
	TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta prote...
TMPH-02106	SH3PXD2A Protein, Human, Recombinant (His & Myc) SH3PXD2A,SH3 multiple domains protein 1,SH3 and PX domain-co...	Human	E. coli
	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
TMPJ-01008	THOP1 Protein, Human, Recombinant (His) THOP1,MP78,Thimet Oligopeptidase,Endopeptidase 24.15	Human	E. coli
	Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degrada...
TMPY-01303	Serpin A3 Protein, Human, Recombinant (His) ACT,GIG25,serpin peptidase inhibitor, clade A (alpha-1 antip...	Human	HEK293 Cells
	SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzy...
TMPH-01503	Humanin Protein, Human, Recombinant (hFc) MT-RNR2,Humanin,Humanin mitochondrial	Human	HEK293 Cells
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....
TMPY-03065	BACE2 Protein, Mouse, Recombinant (His) CEAP1,BAE2,1110059C24Rik,β-site APP-cleaving enzyme 2,CDA13,...	Mouse	HEK293 Cells
	BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is the major β-secretase in vivo. BACE2 is located on chromosome 21 and may play a role in alzheimer's disease pathogenesis in down syndrome(DS). Overexpression of BACE2 by lentivirus markedly reduced amyloid β protein production in primary neurons. Despite an extra copy of the BACE2 ...
TMPH-01502	Humanin Protein, Human, Recombinant (GST) Humanin,Humanin mitochondrial,MT-RNR2	Human	E. coli
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....
TMPY-02063	Alpha-2-macroglobulin Protein, Human, Recombinant (His) α-2-macroglobulin,FWP007,CPAMD5,A2MD,S863-7,alpha-2-macroglo...	Human	Baculovirus Insect Cells
	alpha-2-macroglobulin, also known as α2-macroglobulin (α2M and A2M), is an abundant protein of the plasma of vertebrates and members of several invertebrate phyla and functions as a broad-spectrum protease-binding protein. alpha-2-macroglobulin is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis. alpha-2-macroglobulin is a large plasma glycoprotein that has long been known as an irreversible inhibitor of a variety of proteinases. More recently, it ha...
TMPH-02282	Ubiquilin-1 Protein, Human, Recombinant (His & Myc) Ubiquilin-1,UBQLN1,Protein linking IAP with cytoskeleton 1	Human	E. coli
	Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS), autophagy and endoplasmic reticulum-associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. Plays a role in the ERAD pathway via its in...

重组蛋白

Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02110

Species: Human

Expression System: E. coli

Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02221

Species: Human

Expression System: E. coli

Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)

Cat.No: TMPY-03884

Species: Human

Expression System: E. coli

Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)

Cat.No: TMPY-03885

Species: Human

Expression System: E. coli

APLP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04693

Species: Mouse

Expression System: HEK293 Cells

APLP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03628

Species: Human

Expression System: HEK293 Cells

SNCA Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00684

Species: Mouse

Expression System: E. coli

SNCA Protein, Mouse, Recombinant

Cat.No: TMPJ-00683

Species: Mouse

Expression System: E. coli

SNCA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00023

Species: Human

Expression System: E. coli

APP/Protease nexin-II Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00668

Species: Human

Expression System: HEK293 Cells

LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00338

Species: Human

Expression System: HEK293 Cells

PIEZO1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01863

Species: Human

Expression System: E. coli

APBA2 Protein, Human, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-00928

Species: Human

Expression System: E. coli

APBA2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00929

Species: Human

Expression System: HEK293 Cells

APBA3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00722

Species: Human

Expression System: E. coli

C-ABL/ABL1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

Amyloid Precursor Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00782

Species: Human

Expression System: HEK293 Cells

Mcpt4 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02778

Species: Mouse

Expression System: E. coli

Mcpt1 Protein, Rat, Recombinant (Myc)

Cat.No: TMPH-03328

Species: Rat

Expression System: E. coli

TREM2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00507

Species: Cynomolgus

Expression System: HEK293 Cells

SH3PXD2A Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02106

Species: Human

Expression System: E. coli

THOP1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01008

Species: Human

Expression System: E. coli

Serpin A3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01303

Species: Human

Expression System: HEK293 Cells

Humanin Protein, Human, Recombinant (hFc)

Cat.No: TMPH-01503

Species: Human

Expression System: HEK293 Cells

BACE2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03065

Species: Mouse

Expression System: HEK293 Cells

Humanin Protein, Human, Recombinant (GST)

Cat.No: TMPH-01502

Species: Human

Expression System: E. coli

Alpha-2-macroglobulin Protein, Human, Recombinant (His)

Cat.No: TMPY-02063

Species: Human

Expression System: Baculovirus Insect Cells

Ubiquilin-1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02282

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0170	Homotaurine-d6
	Homotaurine-d6 是 Homotaurine 的氘代化合物。Homotaurine 的 CAS 号为 3687-18-1。Homotaurine 是一种具有口服活性的、可透过血脑屏障的天然氨基酸，存在于各种红色海藻中，能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物，具有神经保护，抗惊厥和抗高血压的活性。

同位素标记化合物

Cat.No: TMID-0170

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