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Search Results for " beta receptor "
Targets Recommended: Adrenergic Receptor

273

抑制剂 & 化合物

45

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化合物库

240

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同位素标记化合物

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Cat. No. Product Name
L4100 TGF-β/Smad靶点化合物库

184 compounds
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选;

化合物库

TGF-β/Smad靶点化合物库
Cat.No: L4100
Compounds: 184
Cat. No. Product Name Target Signaling Pathways
T7065 Tizanidine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Tizanidine 是一种 α2-肾上腺素受体激动剂,能够抑制神经递质从CNS 去甲肾上腺素激活的神经元中释放。
T7160 Lofexidine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Lofexidine 是一种选择性α2 受体激动剂,常用于缓解海洛因和其他阿片类戒断的躯体症状。
T40622 Mapenterol hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Mapenterol hydrochloride 是 β2 肾上腺素受体激动剂。
T13016 SR59230A

Adrenergic Receptor GPCR/G Protein; Neuroscience
SR59230A 是可透过血脑屏障的、选择性的 β3-肾上腺素能受体拮抗剂,对 β3,β1 和 β2 受体的 IC50分别为 40、408 和 648 nM。
T7728 ACEPROMAZINE MALEATE

Dopamine Receptor GPCR/G Protein; Neuroscience
Acepromazine maleate 是一种 α 肾上腺素受体 (alpha-adrenoceptor) 拮抗剂,是一种吩噻嗪类促进安定的试剂。
T19680 Zotepine

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Zotepine 是一种抗精神病剂,是有效的5-HT2A、5-HT2C、组胺H1、α1-肾上腺素能和多巴胺D2受体拮抗剂,Kd 值分别为 2.6、3.2、3.3、7.3 和 8 nM。它在体内表现出抗抑郁和抗焦虑作用。
T8348 Phentolamine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Phentolamine 是一种 alpha-1 和 alpha-2 选择性肾上腺素能受体拮抗剂。
T5471 GUANABENZ

Adrenergic Receptor GPCR/G Protein; Neuroscience
GUANABENZ 是一种中枢 alpha-2 肾上腺素能激动剂。它的作用机制是作为肾上腺素能 α2-激动剂。
T8810 Terbutaline

Adrenergic Receptor GPCR/G Protein; Neuroscience
Terbutaline 是 bambuterol 的活性代谢物,也是β2肾上腺素能受体的短效激动剂,可预防早产及用作支气管扩张剂。
T37906 Dibenamine hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Dibenamine hydrochloride 是竞争性的、不可逆的肾上腺素能阻断剂,可以修饰肾上腺素的药理作用。它对小鼠体内肾上腺素的破坏率显著增加。
T2524 Dexmedetomidine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Dexmedetomidine 是选择性、具有口服活性的 α2 肾上腺素能受体激动剂,Ki=1.08 nM。它对 α1 肾上腺素受体显示出 1620 倍的选择性。它具有抗焦虑活性,可用于研究促进睡眠和缓解疼痛。
T21640 Talinolol

Adrenergic Receptor GPCR/G Protein; Neuroscience
Talinolol 是一种长效、心脏选择性的 β1-肾上腺素能受体阻滞剂,具有心脏保护和抗高血压作用。它也是众所周知且经常使用的 P-糖蛋白 (P-gp) 活性探针底物。
T8580 Bupranolol

Adrenergic Receptor GPCR/G Protein; Neuroscience
Bupranolol 是竞争性的、口服活性的、非选择性的β-adrenoceptor 拮抗剂,无固有的拟交感神经活性。
T13736 Interferon receptor inducer-1

IFNAR Immunology/Inflammation
Interferon receptor inducer-1 是一种干扰素(IFN)受体诱导剂,可用于干扰素诱导参与的紊乱性疾病的研究。
T10830 CL 316243

Adrenergic Receptor GPCR/G Protein; Neuroscience
CL316243 是一种高效的 β3 肾上腺素受体选择性激动剂,EC50 为 3 nM。它是一种有效的脂肪细胞脂解刺激剂,可增加棕色脂肪组织的产热和代谢率,具有治疗肥胖症、糖尿病和急迫性尿失禁的潜力。
T5511 L-765314

Adrenergic Receptor GPCR/G Protein; Neuroscience
L-765314 是一种 α1b 肾上腺素能受体的选择性拮抗剂,其在大鼠和人体中的Ki 分别为 5.4 nM 和 2.0 nM。
T8708 Paroxetine

Serotonin Transporter Neuroscience
Paroxetine 是选择性血清素再摄取抑制剂,是苯基哌啶的衍生物。 它对于甲肾上腺素摄取抑制功能较弱,但比该位点其他SSRIs 更有效。
T6641 Rilmenidine Phosphate

Apoptosis; Adrenergic Receptor; Autophagy; Imidazoline Receptor Apoptosis; Autophagy; GPCR/G Protein; Neuroscience
Rilmenidine phosphate 是一种新型的抗高血压药物和口服活性选择性 I1 咪唑啉受体激动剂。它可调节白血病细胞增殖,刺激促凋亡蛋白 Bax,从而诱导人白血病 K562 细胞线粒体通路的紊乱和凋亡。它可通过减少交感神经过度活跃而发挥中枢作用,并通过抑制 Na+/H+反向转运而在肾脏中发挥作用。
T0165 Urapidil

Mediatensyl,乌拉地尔,Ebrantil,Eupressyl

5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
Urapidil (Ebrantil) 是交感神经抗高血压药物,可作为 5-HT1A 受体激动剂和 α1-肾上腺素受体拮抗剂。
T16759 Ritanserin

利坦丝林,R 55667

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Ritanserin (R 55667) 是一种长效、高效、相对选择性、可口服的5-HT2受体拮抗剂,IC50值为 0.9 nM。
T22406 Prazosin

哌唑嗪,Prazosine,Furazosin,Prazocin

Adrenergic Receptor GPCR/G Protein; Neuroscience
Prazosin (Prazosine) 是一种 α1 受体阻滞剂,是一种 α1 肾上腺素能受体的反向激动剂,用于治疗高血压。
T12829 Salmeterol

沙美特罗,GR33343X

Adrenergic Receptor GPCR/G Protein; Neuroscience
Salmeterol (GR33343X) 是一种选择性的人β2肾上腺素受体激动剂。它能够有效刺激 cAMP 积累,作用于 CHO 细胞,对人β2,β1和β3肾上腺素受体的 pEC50分别为 9.6、6.1 和 5.9。
T11318 Dopexamine hydrochloride

盐酸多培沙明,FPL60278AR

Adrenergic Receptor GPCR/G Protein; Neuroscience
Dopexamine hydrochloride (FPL60278AR) 是β2肾上腺素能受体激动剂。
T2320 Indacaterol

Adrenergic Receptor GPCR/G Protein; Neuroscience
Indacaterol 是一种超长效β-肾上腺素受体激动剂。
T0088 Urapidil hydrochloride

Urapidil HCl,盐酸乌拉地尔

5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
Urapidil hydrochloride (Urapidil HCl) 是α1-肾上腺素受体拮抗剂和5-HT1A 受体激动剂。
T12402 Penbutolol sulfate

(-)-Terbuclomine,喷布特罗硫酸盐

Adrenergic Receptor GPCR/G Protein; Neuroscience
Penbutolol sulfate ((-)-Terbuclomine) 是一种非选择性的β阻滞剂,能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型)。Penbutolol 是拟交感神经药,可用于高血压的研究。
T6872 L755507

Adrenergic Receptor; CRISPR/Cas9 DNA Damage/DNA Repair; GPCR/G Protein; Neuroscience
L755507 是一种有效的选择性β3-AR 激动剂,IC50值为 35 nM。
T8358 Fenoterol

Adrenergic Receptor GPCR/G Protein; Neuroscience
Fenoterol 是一种拟交感神经剂,是一种选择性的,具有口服活性 β2-肾上腺素受体 (β2-adrenoceptor) 激动剂,是一种有效的支气管扩张剂,可用于一种与哮喘、支气管炎和其他阻塞性气道疾病相关的支气管痉挛。
T2231 Estradiol dipropionate

17-Beta-Estradiol-3,17-Dipropionate,3,17-二丙酸-17-BETA-雌二酯,二丙酸雌二醇

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Progesterone Receptor Endocrinology/Hormones; Others
Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) 是雌激素-孕激素的组合物,可用作雌激素 (estrogen) 孕激素 (progesterone) 激动剂。
T13376 YS-49

RAAS; Akt; PI3K; Adrenergic Receptor Cytoskeletal Signaling; Endocrinology/Hormones; GPCR/G Protein; Neuroscience; PI3K/Akt/mTOR signaling
YS-49 是一种PI3K/Akt(RhoA 的下游靶标) 的激活剂,可减少 3-甲基胆碱处理的细胞中 RhoA/PTEN 的激活。它是异喹啉化合物生物碱,因能激活心脏β-adrenoceptors 而具有强烈的正性肌力作用。它能通过诱导血红素加氧酶来抑制血管紧张素 II 刺激 VSMC 细胞的增殖。
T1012 Acebutolol hydrochloride

盐酸醋丁洛尔,Acebutolol HCl

Adrenergic Receptor GPCR/G Protein; Neuroscience
Acebutolol hydrochloride (Acebutolol HCl) 是一种 β-肾上腺素受体拮抗剂,用于研究高血压、心绞痛和心律失常。
T17111 Todralazine hydrochloride

Ecarazine hydrochloride,盐酸托屈嗪

Adrenergic Receptor GPCR/G Protein; Neuroscience
Todralazine hydrochloride (Ecarazine hydrochloride) 是一种 β2AR 阻滞剂,具有抗氧化和自由基清除活性。 Todralazine hydrochloride 可用于抗高血压的研究。
T7045 Clonidine

Nexiclon,Catapres,Kapvay,可乐定

Adrenergic Receptor GPCR/G Protein; Neuroscience
Clonidine (Kapvay) 是 alpha2 肾上腺素能激动剂。
T1180 Blonanserin

布南色林,AD-5423

Dopamine Receptor; Sigma receptor; 5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
Blonanserin (AD-5423) 是一种有效的5-HT2A 和多巴胺 D2 受体拮抗剂,Ki 为 0.812 和 0.142 nM,是一种非典型的抗精神病试剂。
T3284 Carazolol

Conducton,Suacron,咔唑心安

Adrenergic Receptor GPCR/G Protein; Neuroscience
Carazolol (Suacron) 是高效的 β1/β2 肾上腺素受体拮抗剂,也是高效 β3肾上腺素受体选择性激动剂,可用于高血压的研究。
T22316 Doxazosin

UK 33274,多沙唑嗪

Adrenergic Receptor GPCR/G Protein; Neuroscience
Doxazosin (UK 33274) 是选择性的拮抗突触后的α1肾上腺素受体。
T1132 Nicergoline

尼麦角林,Nicergolinum,Nimergoline

Adrenergic Receptor GPCR/G Protein; Neuroscience
Nicergoline (Nicergolinum) 是一种有效的,选择性的、具有口服活性的α1A-肾上腺素能受体拮抗剂,是一种溴烟碱酸的麦角林衍生物。它具有血管舒张作用,可以改善阿尔茨海默症小鼠的认知功能。
T21957 Guanabenz hydrochloride

NE56490

Adrenergic Receptor GPCR/G Protein; Neuroscience
Guanabenz hydrochloride (NE56490) 是一种具有降血压作用的口服活性 α2-肾上腺素受体激动剂。
T12933 SM-276001

TLR; COX Immunology/Inflammation; Neuroscience
SM-276001 是可口服的干扰素诱导剂,是选择性TLR7激动剂,可以诱导抗肿瘤免疫反应。
T2546 Pimozide

R6238,匹莫奇特,匹莫齐特

Potassium Channel; Dopamine Receptor; Adrenergic Receptor; STAT GPCR/G Protein; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Stem Cells
Pimozide (R6238) 是多巴胺受体拮抗剂,对多巴胺 D1、D2 和 D3 受体的 Ki 值分别为 588、1.4 和 2.5 nM。它也是STAT3和STAT5的抑制剂,对 α1 肾上腺素受体也有较高亲和性,Ki 值为 39 nM。
T3278 Piribedil

EU-4200,Trivastan,ET-495,Trivastal

Dopamine Receptor; Histone Methyltransferase; Adrenergic Receptor Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
Piribedil (Trivastan) 是多巴胺 D2受体激动剂,对 hα1A-肾上腺素受体也显示出拮抗作用。
T6562 Latrepirdine dihydrochloride

Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin

Beta Amyloid; 5-HT Receptor; Adrenergic Receptor; GluR; Autophagy; Histamine Receptor Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) 是一种具有口服活性和神经活性的多种药物靶点的拮抗剂,可刺激淀粉样前体蛋白分解代谢和 β-淀粉样蛋白分泌。
T0394 Moxisylyte hydrochloride

莫西赛利盐酸盐,Thymoxamine hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Moxisylyte hydrochloride (Thymoxamine hydrochloride) 是一种 alpha 1-blocker 的拮抗剂,能在不减少血管压力的情况下,扩张大脑血管。
T1247 Clonidine hydrochloride

Clonidine HCl,Catapres,盐酸可乐定

Adrenergic Receptor GPCR/G Protein; Neuroscience
Clonidine hydrochloride (Catapres) 是一种α2-adrenoceptor 激动剂,是一种抗高血压药。
T1671 Mirabegron

YM178,米拉贝隆

Adrenergic Receptor GPCR/G Protein; Neuroscience
Mirabegron (YM178) 是选择性的肾上腺素受体激动剂,EC50=22.4 nM。
T1090 Perphenazine

Perphenazin,Etaperazine,Trilafon,奋乃静

CaMK; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Perphenazine (Trilafon) 是吩噻嗪衍生物和多巴胺拮抗剂,具有止吐和抗精神病特性。它能够抑制5-HT2A 受体,α1A 肾上腺素能受体,多巴胺D2、D3、D2L 受体,以及组胺H1受体,对应的Ki 值分别为5.6、10、0.765、0.13、3.4 和 8 nM。
T0115 Idazoxan hydrochloride

RX 781094,盐酸咪唑克生

Adrenergic Receptor; Imidazoline Receptor GPCR/G Protein; Neuroscience
Idazoxan hydrochloride (RX 781094) 是一种 α2-肾上腺素受体拮抗剂,改善帕金森氏病、L-DOPA 引起的运动障碍和实验性帕金森病的运动症状。它也是咪唑啉受体拮抗剂,可竞争性拮抗唑啉样药物的中枢性降压作用。
T2306 Brexpiprazole

依匹哌唑,OPC-34712,依匹唑派

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
Brexpiprazole (OPC-34712) 是人5-HT1A 和多巴胺受体的部分激动剂,Ki 分别为0.12 和 0.3 nM。它也是5-HT2A 受体的拮抗剂,Ki 为 0.47 nM,可作为非典型抗精神病药。
T16708 R-268712

ALK; TGF-beta/Smad Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
R-268712 是选择性的 ALK5 抑制剂(IC50:2.5 nM)。
T0137 Mirtazapine

米氮平,6-Azamianserin,Org3770

Dopamine Receptor; 5-HT Receptor; Opioid Receptor; Adrenergic Receptor; Histamine Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Mirtazapine (6-Azamianserin) 是一种有效的具有口服活性的去甲肾上腺素能和特异性血清素能抗抑郁剂 (NaSSA)。它也是一种5-HT2、5-HT3、组胺 H1 受体和 α2-肾上腺素受体拮抗剂,pKi 值分别为 8.05、8.1、9.3 和 6.95。

化合物

Tizanidine
Cat.No: T7065
Synonym:
Target: Adrenergic Receptor
Lofexidine
Cat.No: T7160
Synonym:
Target: Adrenergic Receptor
Mapenterol hydrochloride
Cat.No: T40622
Synonym:
Target: Adrenergic Receptor
SR59230A
Cat.No: T13016
Synonym:
Target: Adrenergic Receptor
ACEPROMAZINE MALEATE
Cat.No: T7728
Synonym:
Target: Dopamine Receptor
Zotepine
Cat.No: T19680
Synonym:
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Phentolamine
Cat.No: T8348
Synonym:
Target: Adrenergic Receptor
GUANABENZ
Cat.No: T5471
Synonym:
Target: Adrenergic Receptor
Terbutaline
Cat.No: T8810
Synonym:
Target: Adrenergic Receptor
Dibenamine hydrochloride
Cat.No: T37906
Synonym:
Target: Adrenergic Receptor
Dexmedetomidine
Cat.No: T2524
Synonym:
Target: Adrenergic Receptor
Talinolol
Cat.No: T21640
Synonym:
Target: Adrenergic Receptor
Bupranolol
Cat.No: T8580
Synonym:
Target: Adrenergic Receptor
Interferon receptor inducer-1
Cat.No: T13736
Synonym:
Target: IFNAR
CL 316243
Cat.No: T10830
Synonym:
Target: Adrenergic Receptor
L-765314
Cat.No: T5511
Synonym:
Target: Adrenergic Receptor
Paroxetine
Cat.No: T8708
Synonym:
Target: Serotonin Transporter
Rilmenidine Phosphate
Cat.No: T6641
Synonym:
Target: Apoptosis, Adrenergic Receptor, Autophagy, Imidazoline Receptor
Urapidil
Cat.No: T0165
Synonym: Mediatensyl,乌拉地尔,Ebrantil,Eupressyl
Target: 5-HT Receptor, Adrenergic Receptor
Ritanserin
Cat.No: T16759
Synonym: 利坦丝林,R 55667
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Prazosin
Cat.No: T22406
Synonym: 哌唑嗪,Prazosine,Furazosin,Prazocin
Target: Adrenergic Receptor
Salmeterol
Cat.No: T12829
Synonym: 沙美特罗,GR33343X
Target: Adrenergic Receptor
Dopexamine hydrochloride
Cat.No: T11318
Synonym: 盐酸多培沙明,FPL60278AR
Target: Adrenergic Receptor
Indacaterol
Cat.No: T2320
Synonym:
Target: Adrenergic Receptor
Urapidil hydrochloride
Cat.No: T0088
Synonym: Urapidil HCl,盐酸乌拉地尔
Target: 5-HT Receptor, Adrenergic Receptor
Penbutolol sulfate
Cat.No: T12402
Synonym: (-)-Terbuclomine,喷布特罗硫酸盐
Target: Adrenergic Receptor
L755507
Cat.No: T6872
Synonym:
Target: Adrenergic Receptor, CRISPR/Cas9
Fenoterol
Cat.No: T8358
Synonym:
Target: Adrenergic Receptor
Estradiol dipropionate
Cat.No: T2231
Synonym: 17-Beta-Estradiol-3,17-Dipropionate,3,17-二丙酸-17-BETA-雌二酯,二丙酸雌二醇
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Progesterone Receptor
YS-49
Cat.No: T13376
Synonym:
Target: RAAS, Akt, PI3K, Adrenergic Receptor
Acebutolol hydrochloride
Cat.No: T1012
Synonym: 盐酸醋丁洛尔,Acebutolol HCl
Target: Adrenergic Receptor
Todralazine hydrochloride
Cat.No: T17111
Synonym: Ecarazine hydrochloride,盐酸托屈嗪
Target: Adrenergic Receptor
Clonidine
Cat.No: T7045
Synonym: Nexiclon,Catapres,Kapvay,可乐定
Target: Adrenergic Receptor
Blonanserin
Cat.No: T1180
Synonym: 布南色林,AD-5423
Target: Dopamine Receptor, Sigma receptor, 5-HT Receptor, Adrenergic Receptor
Carazolol
Cat.No: T3284
Synonym: Conducton,Suacron,咔唑心安
Target: Adrenergic Receptor
Doxazosin
Cat.No: T22316
Synonym: UK 33274,多沙唑嗪
Target: Adrenergic Receptor
Nicergoline
Cat.No: T1132
Synonym: 尼麦角林,Nicergolinum,Nimergoline
Target: Adrenergic Receptor
Guanabenz hydrochloride
Cat.No: T21957
Synonym: NE56490
Target: Adrenergic Receptor
SM-276001
Cat.No: T12933
Synonym:
Target: TLR, COX
Pimozide
Cat.No: T2546
Synonym: R6238,匹莫奇特,匹莫齐特
Target: Potassium Channel, Dopamine Receptor, Adrenergic Receptor, STAT
Piribedil
Cat.No: T3278
Synonym: EU-4200,Trivastan,ET-495,Trivastal
Target: Dopamine Receptor, Histone Methyltransferase, Adrenergic Receptor
Latrepirdine dihydrochloride
Cat.No: T6562
Synonym: Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin
Target: Beta Amyloid, 5-HT Receptor, Adrenergic Receptor, GluR, Autophagy, Histamine Receptor
Moxisylyte hydrochloride
Cat.No: T0394
Synonym: 莫西赛利盐酸盐,Thymoxamine hydrochloride
Target: Adrenergic Receptor
Clonidine hydrochloride
Cat.No: T1247
Synonym: Clonidine HCl,Catapres,盐酸可乐定
Target: Adrenergic Receptor
Mirabegron
Cat.No: T1671
Synonym: YM178,米拉贝隆
Target: Adrenergic Receptor
Perphenazine
Cat.No: T1090
Synonym: Perphenazin,Etaperazine,Trilafon,奋乃静
Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Idazoxan hydrochloride
Cat.No: T0115
Synonym: RX 781094,盐酸咪唑克生
Target: Adrenergic Receptor, Imidazoline Receptor
Brexpiprazole
Cat.No: T2306
Synonym: 依匹哌唑,OPC-34712,依匹唑派
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
R-268712
Cat.No: T16708
Synonym:
Target: ALK, TGF-beta/Smad
Mirtazapine
Cat.No: T0137
Synonym: 米氮平,6-Azamianserin,Org3770
Target: Dopamine Receptor, 5-HT Receptor, Opioid Receptor, Adrenergic Receptor, Histamine Receptor
Cat. No. Product Name Target Signaling Pathways
TN1015 Meranzin

Adrenergic Receptor; Immunology/Inflammation related GPCR/G Protein; Immunology/Inflammation; Neuroscience
Meranzin 是从传统中药 Chaihu-Shugan-San (CSS) 中的生物活性化合物,是从紫茉莉叶中分离出的,能够调节共有的 α2-肾上腺素受体,并参与 AMPA-ERK1/2-BDNF 信号传导。它有潜在的预防动脉粥样硬化和抑郁症合并症。
T3865 beta-Eudesmol

β-桉叶醇,Beta-Selinenol,beta-桉叶醇

TRP/TRPV Channel; AChR Membrane transporter/Ion channel; Neuroscience
beta-Eudesmol (Beta-Selinenol) 是天然的含氧倍半萜烯,可激活hTRPA1,EC50值为 32.5 μM。Beta-Eudesmol 有增加食欲的功效。
T6S2140 β-Anhydroicaritin

Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素

MMP; Others; TNF; Interleukin Apoptosis; Immunology/Inflammation; Others; Proteases/Proteasome
β-Anhydroicaritin 是从乳香提取的一种天然产物,具有重要的生物学和药理学作用,如抗骨质疏松症,雌激素调节和抗肿瘤特性。它改善牙周组织的降解,抑制糖尿病大鼠 TNF-α 和 MMP-3 的合成和分泌。它抑制细胞内 Ca2+的升高,并显著降低 iNOS 蛋白的表达。
TN1465 Cannabigerol

NOS; 5-HT Receptor; ROS GPCR/G Protein; Immunology/Inflammation; Neuroscience
Cannabigerol 是一种植物大麻素,是一种高亲和力 α2-肾上腺素能受体激动剂、中度亲和力 5-HT1A 受体拮抗剂和低亲和力 CB1/CB2受体拮抗剂。它可降低眼压,有潜力治疗青光眼。
T6662 Scopine

东莨菪醇,6,7-Epoxytropine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Scopine (6,7-Epoxytropine) 是一种山莨菪碱的代谢物,是一种 α1-肾上腺素受体激动剂,用于治疗急性循环性休克。
TN1440 Beta-Hydroxyisovalerylshikonin

EGFR; Tyrosine Kinases; Prostaglandin Receptor; Src; AMPK; Fatty Acid Synthase Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Beta-hydroxyisovalerylshikonin 是分离自Lithospermium radix 的天然产物,具有抑制PTK 的作用, 对 EGFR 和 v-Src 受体作用的IC50分别为 0.7 μM 和 1 μM。它对多种肿瘤细胞系均有抑制作用,可以高效诱导 NCI-H522 和 DMS114 细胞的死亡。
T0076 Paliperidone

9-羟基利培酮,帕潘立酮,9-hydroxyrisperidone

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Paliperidone (9-hydroxyrisperidone) 是 Risperidone 的主要活性代谢产物,是多巴胺 D2 拮抗剂和5-HT2A 拮抗剂。它用作非典型抗精神病药,用于精神分裂症的急性及维持治疗。它对α1和α2肾上腺素能受体和 H1组胺能受体也有拮抗作用。
T6519 Gramine

NSC 16892,芦竹碱,Donaxine

Adiponectin receptor; Reverse Transcriptase; Adrenergic Receptor GPCR/G Protein; Microbiology/Virology; Neuroscience
Gramine (Donaxine) 是从芦竹中得到的一种生物碱,是脂联素受体激动剂,对 AdipoR2 和 AdipoR1 的 IC50值分别为 3.2 和 4.2 µM。它也是小鼠和人β2-肾上腺素受体激动剂,具有抗肿瘤、抗炎和抗病毒作用。
TN1182 11-​Keto-​beta-​boswellic acid

11-Keto-beta-boswellic acid,11-酮基-BETA-乳香酸

Leukotriene Receptor; NF-κB; Lipoxygenase GPCR/G Protein; Metabolism; NF-κB
11-Keto-beta-boswellic acid 是来自乳香的一种五环三萜酸,具有抗炎活性和剂量依赖性心脏保护作用,主要是由于抑制5-脂氧合酶、白三烯、NF-κB 的激活和肿瘤坏死因子 α 的产生。
T1287 Synephrine

辛弗林,Oxedrine

Endogenous Metabolite; Adrenergic Receptor GPCR/G Protein; Metabolism; Neuroscience
Synephrine (Oxedrine) 是来自 Citrus aurantium 的α-adrenergic 和β-adrenergic 激动剂,是一种生物碱。它也是一种拟交感神经化合物,能够用于减肥。
T2142 Yohimbine hydrochloride

盐酸育亨宾,Antagonil,Yohimbine HCl

Adrenergic Receptor GPCR/G Protein; Neuroscience
Yohimbine hydrochloride (Antagonil) 是一种植物生物碱,具有 α-2-肾上腺素能阻断活性。它被用作散瞳药和治疗勃起功能障碍。
T3829 Ginsenoside F3

人参皂苷F3

Others; IFNAR; Interleukin Immunology/Inflammation; Others
Ginsenoside F3 是一种皂苷,提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达,有免疫增强的作用。
T8149 Dobutamine hydrochloride

盐酸多巴酚丁胺,Dobutamine (hydrochloride)

Adrenergic Receptor GPCR/G Protein; Neuroscience
Dobutamine hydrochloride (Dobutamine(hydrochloride)) 是一种合成的儿茶酚胺,可作用于肾上腺素能受体α1-AR、β1-AR 和β2-AR,是一种选择性的 β1-AR 受体激动剂,对 α1-AR 和 β2-AR 作用相对较弱。它能够增加心输出量,矫正低灌注。
TN2081 Maohuoside A

MAPK MAPK
Maohuoside A 是从 E. koreanum 中分离出的单一化合物,具有促进成骨作用。它能够利用 MAPK 信号通路骨及形态发生蛋白 (BMP) ,促进骨髓间充质干细胞的成骨作用。
T1633 β-Carotene

beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素

Apoptosis; ROS; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Metabolism
β-Carotene (Provitamin A) 是一种天然存在的视黄醇(维生素 A)前体。它是一种 ROS 调节剂,具有抗氧化和抗炎活性。它可作为抗氧化剂或者促氧化剂,可诱导乳腺癌细胞凋亡,具有抗癌活性。
T17310 Phenylephrine

去氧肾上腺素,L-Phenylephrine,去氧肾上腺素碱,(R)-(-)-Phenylephrine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Phenylephrine ((R)-(-)-Phenylephrine) 是一种选择性的α1-肾上腺素受体激动剂,常用作减充血剂。
T3158 Harmane

Loturine,Harman,Aribine,哈尔满碱

Adrenergic Receptor; Monoamine Oxidase; Imidazoline Receptor GPCR/G Protein; Neuroscience
Harmane (Loturine) 是一种在咖啡和烟草烟雾中发现的 β-咔啉生物碱,是有效的神经毒素,可引起严重的动作震颤和精神病学表现。它还是选择性的单胺氧化酶抑制剂,具有致突变作用,对 MAO A/B 的 IC50值分别为 0.5 和 5 μM。
T5S2059 Glaucine

Calcium Channel; Dopamine Receptor; Influenza Virus; Adrenergic Receptor; PDE GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
Glaucine 是从海罂粟中分离的一种生物碱,具有镇咳、抗炎和支气管扩张作用。它是具有口服活性的磷酸二酯酶 4 选择性抑制剂。它还是非选择性的 α-肾上腺素受体拮抗剂,具有抗氧化和抗病毒活性。
T13655 DL-Norepinephrine hydrochloride

去甲肾上腺素盐酸盐,Lys,DL-lysine

Adrenergic Receptor GPCR/G Protein; Neuroscience
DL-Norepinephrine hydrochloride (DL-lysine) 是一种靶向α1 adrenoceptor 和β1 adrenoceptor 的神经递质,可降低心内膜下氧分压。它是一种模拟内源性去甲肾上腺素的拟交感神经作用的合成苯乙胺。
T9114 β-Caryophyllene

(-)-(E)-Caryophyllene,β-石竹烯,(−)-β-caryophyllene,(−)-trans-Caryophyllene

Cannabinoid Receptor; Endogenous Metabolite GPCR/G Protein; Metabolism
β-Caryophyllene ((-)-(E)-Caryophyllene) 是 CB2受体激动剂。
T5281 Skatole

粪臭素,Scatole,3-Methylindole,3-​Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole

AhR; p38 MAPK; Aryl Hydrocarbon Receptor; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
Skatole (3-Methyl-1H-indole) 是由肠道菌群产生的,通过激活芳基烃受体和 p38调节肠上皮细胞功能。
T6688 Synephrine hydrochloride

辛弗林盐酸盐,Oxedrine hydrochloride,Synephrine HCl

Endogenous Metabolite; Adrenergic Receptor GPCR/G Protein; Metabolism; Neuroscience
Synephrine hydrochloride (Oxedrine hydrochloride) 是一种来自Citrus aurantium 的α-adrenergic 和β-adrenergic 激动剂的生物碱,也是一种拟交感神经化合物,能够用于减肥。
T7044 Norepinephrine

去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol

MMP; Endogenous Metabolite; Adrenergic Receptor; Autophagy Autophagy; GPCR/G Protein; Metabolism; Neuroscience; Proteases/Proteasome
Norepinephrine (Levophed) 属于生物碱类天然产物,是一种神经递质,一种肾上腺素能受体 (AR) 的激动剂,对 α1、α2 和 β1 AR 具有激活活性。Norepinephrine 被用作抗休克的血管活性剂。
T0453 Phenylephrine hydrochloride

NCI-c55641,Phenylephrine HCl,盐酸去氧肾上腺素,(R)-(-)-Phenylephrine hydrochloride

Endogenous Metabolite; Adrenergic Receptor GPCR/G Protein; Metabolism; Neuroscience
Phenylephrine hydrochloride (NCI-c55641) 是选择性的α1-肾上腺素能受体激动剂,对α1A,α1B 和α1D 受体的pKis 分为4.70,4.87和5.86。
T2889 Isoferulic acid

Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸

Influenza Virus; Adrenergic Receptor GPCR/G Protein; Microbiology/Virology; Neuroscience
Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物,有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体,增强 β-内啡肽的分泌并增加体外葡萄糖的使用。
T7056 Dronedarone

决奈达隆,SR 33589

P450; Potassium Channel; Calcium Channel; Sodium Channel; Adrenergic Receptor; AChR; Autophagy Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
Dronedarone (SR 33589) 是一种胺碘酮类似物,对治疗心房颤动可能有效。它是CYP3A4的底物和中度抑制剂。它是多种离子电流的有效阻滞剂,通过非竞争性结合到肾上腺素能受体显示出抗肾上腺素能的效果。
T0505 Methyldopa

L-(-)-α-Methyldopa,MK-351,甲基多巴

Dopamine Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
L-(-)-α-Methyldopa (MK-351) 是一种前药,在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂,对 α2- adrenergic receptors 有选择性。
T0469 Octopamine hydrochloride

章鱼胺盐酸盐,(±)-p-Octopamine hydrochlorid,(+,-)-Octopamine HCl,章胺盐酸盐

Dopamine Receptor; Endogenous Metabolite; Adrenergic Receptor GPCR/G Protein; Metabolism; Neuroscience
Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) 是一种与去甲肾上腺素结构相关的生物单胺类物质,在无脊椎动物中起着神经调节剂、神经激素和神经递质的作用。它对转染人 alpha2-肾上腺素受体(ARs)的中国仓鼠卵巢细胞 α2-ARs 有刺激作用。它提高糖原分解、糖酵解、糖异生、摄氧量和门脉灌注压。
T7299 β-Estradiol 17-acetate

β-雌二醇 17-乙酸酯,17-乙酸-17-BETA-雌二酯,beta-estradiol 17-acetate,1,3,5(10)-Estratriene-3,17β-diol 17-acetate

Estrogen Receptor/ERR; Others Endocrinology/Hormones; Others
β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) 是一种雌二醇代谢物。
T3232 Higenamine hydrochloride

Higenamine HCl,Demethylcoclaurine hydrochloride,盐酸去甲乌头碱,norcoclaurine HCl,(+-)-Demethylcoclaurine hydrochloride,Higenamine Hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Higenamine hydrochloride (norcoclaurine HCl) 是一种 β2-AR 激动剂,是用于心力衰竭相关研究的中药乌头的关键成分,具有抗凋亡活性。
TCS2185 Yohimbine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Yohimbine 是一种有效的、相对非选择性的α2 - 肾上腺素能受体拮抗剂,IC50=0.6μM。
T1064 Norepinephrine bitartrate monohydrate

酒石酸去甲肾上腺素,Levophed,Noradrenaline bitartrate monohydrate,降肾上腺素

Endogenous Metabolite; Adrenergic Receptor; Autophagy Autophagy; GPCR/G Protein; Metabolism; Neuroscience
Norepinephrine bitartrate monohydrate (Levophed) 是一种β1-选择性的肾上腺素能受体激动剂,EC50为 5.37 μM。
T5247 Trimethylamine N-oxide dihydrate

二水氧化三甲胺,TMANO Dihydrate

Others; Endogenous Metabolite Metabolism; Others
Trimethylamine N-oxide dihydrate (TMANO Dihydrate) 是内源性代谢产物的一种。
T4429 Rauwolscine hydrochloride

Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Rauwolscine hydrochloride (Isoyohimbine hydrochloride) 是一种高选择性的 α2 adrenergic 受体拮抗剂,Ki=12 nM。
T1680 Tolazoline hydrochloride

Imidaline hydrochloride,苯甲唑啉盐酸盐,Imidaline (hydrochloride),Benzidazol hydrochloride,Tolazoline HCl,NSC35110 (hydrochloride)

Adrenergic Receptor GPCR/G Protein; Neuroscience
Tolazoline hydrochloride (NSC35110(hydrochloride)) 是一种 α 肾上腺素受体抑制剂。
T2207 Adrenosterone

肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G

Androgen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Adrenosterone (11-ketoandrostenedione) 是一种人内源性代谢物,由肾上腺皮质产生。Adrenosterone 是一种竞争性羟基类固醇脱氢酶 1 抑制剂。它是一种的类固醇激素,具有较弱的雄激素特性。它是一种膳食补充剂,能够减少脂肪并提高肌肉质量。它能够抑制人类癌细胞的转移进展。
T1048 Estradiol

雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Estradiol (E2) 是一种天然的类固醇性激素,对于女性生育能力和第二性征的维持至关重要。Estradiol 通过雌激素受体 β (ERβ) 上调 IL-6 表达。
T2882 Genistin

染料木甙,Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside,染料木苷

Apoptosis; Estrogen Receptor/ERR; Others Apoptosis; Endocrinology/Hormones; Others
Genistin (Genistoside) 是一种植物雌激素家族的异黄酮,是一种抗脂肪生成剂。它通过调节ERalpha 信号通路抑制乳腺癌细胞生长和促进凋亡细胞死亡。
T3806 kaempferide

Kaempferol 4'-O-methyl ether,山奈素,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Influenza Virus; Antibacterial; Autophagy Autophagy; Endocrinology/Hormones; Microbiology/Virology
kaempferide (4'-Methylkaempferol) 是一种存在于山柰中的O-甲基化黄酮醇,具有抗病毒活性。
T21532 Anisodamine

6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine

AChR Neuroscience
Anisodamine (6-beta-Hydroxyhyoscyamine) 是毒蕈碱和烟碱胆碱受体的拮抗剂,对毒蕈碱受体的亲和力与东莨菪碱和阿托品相似。 Anisodamine 改善休克状态下的微循环,可用于有机磷中毒的研究。
TJS0341 7-Amino-4-(trifluoromethyl)coumarin

香豆素151,Coumarin 151,AFC,7-氨基-4-(三氟甲基)香豆素

5-HT Receptor GPCR/G Protein; Neuroscience
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是一种荧光标记物,其激发和发射波长分别为400和500 nm,可用来灵敏的检测蛋白酶。
T36914 2-Hydroxyanthraquinone

Others Others
2-Hydroxyanthraquinone 是一种天然产物,显示出抗肿瘤和免疫抑制活性。
TN1787 Isomucronulatol 7-O-glucoside

Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷

Others Others
Isomucronulatol 7-O-beta-glucoside 具有潜在的抗炎活性,在体外对 LPS 刺激产生的 IL-12 p40 表现出微弱的抑制作用。
T6491 (-)-(S)-Equol

(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
(-)-(S)-Equol (4',7-Dihydroxyisoflavan) 是雌激素受体β的高亲和力配体。
T36295 Echistatin TFA

Others Others
Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. [1]. J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.[2]. ...

天然产物

Meranzin
Cat.No: TN1015
Synonym:
Target: Adrenergic Receptor, Immunology/Inflammation related
beta-Eudesmol
Cat.No: T3865
Synonym: β-桉叶醇,Beta-Selinenol,beta-桉叶醇
Target: TRP/TRPV Channel, AChR
β-Anhydroicaritin
Cat.No: T6S2140
Synonym: Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素
Target: MMP, Others, TNF, Interleukin
Cannabigerol
Cat.No: TN1465
Synonym:
Target: NOS, 5-HT Receptor, ROS
Scopine
Cat.No: T6662
Synonym: 东莨菪醇,6,7-Epoxytropine
Target: Adrenergic Receptor
Beta-Hydroxyisovalerylshikonin
Cat.No: TN1440
Synonym:
Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase
Paliperidone
Cat.No: T0076
Synonym: 9-羟基利培酮,帕潘立酮,9-hydroxyrisperidone
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Gramine
Cat.No: T6519
Synonym: NSC 16892,芦竹碱,Donaxine
Target: Adiponectin receptor, Reverse Transcriptase, Adrenergic Receptor
11-​Keto-​beta-​boswellic acid
Cat.No: TN1182
Synonym: 11-Keto-beta-boswellic acid,11-酮基-BETA-乳香酸
Target: Leukotriene Receptor, NF-κB, Lipoxygenase
Synephrine
Cat.No: T1287
Synonym: 辛弗林,Oxedrine
Target: Endogenous Metabolite, Adrenergic Receptor
Yohimbine hydrochloride
Cat.No: T2142
Synonym: 盐酸育亨宾,Antagonil,Yohimbine HCl
Target: Adrenergic Receptor
Ginsenoside F3
Cat.No: T3829
Synonym: 人参皂苷F3
Target: Others, IFNAR, Interleukin
Dobutamine hydrochloride
Cat.No: T8149
Synonym: 盐酸多巴酚丁胺,Dobutamine (hydrochloride)
Target: Adrenergic Receptor
Maohuoside A
Cat.No: TN2081
Synonym:
Target: MAPK
β-Carotene
Cat.No: T1633
Synonym: beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素
Target: Apoptosis, ROS, Endogenous Metabolite
Phenylephrine
Cat.No: T17310
Synonym: 去氧肾上腺素,L-Phenylephrine,去氧肾上腺素碱,(R)-(-)-Phenylephrine
Target: Adrenergic Receptor
Harmane
Cat.No: T3158
Synonym: Loturine,Harman,Aribine,哈尔满碱
Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor
Glaucine
Cat.No: T5S2059
Synonym:
Target: Calcium Channel, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, PDE
DL-Norepinephrine hydrochloride
Cat.No: T13655
Synonym: 去甲肾上腺素盐酸盐,Lys,DL-lysine
Target: Adrenergic Receptor
β-Caryophyllene
Cat.No: T9114
Synonym: (-)-(E)-Caryophyllene,β-石竹烯,(−)-β-caryophyllene,(−)-trans-Caryophyllene
Target: Cannabinoid Receptor, Endogenous Metabolite
Skatole
Cat.No: T5281
Synonym: 粪臭素,Scatole,3-Methylindole,3-​Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole
Target: AhR, p38 MAPK, Aryl Hydrocarbon Receptor, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal
Synephrine hydrochloride
Cat.No: T6688
Synonym: 辛弗林盐酸盐,Oxedrine hydrochloride,Synephrine HCl
Target: Endogenous Metabolite, Adrenergic Receptor
Norepinephrine
Cat.No: T7044
Synonym: 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol
Target: MMP, Endogenous Metabolite, Adrenergic Receptor, Autophagy
Phenylephrine hydrochloride
Cat.No: T0453
Synonym: NCI-c55641,Phenylephrine HCl,盐酸去氧肾上腺素,(R)-(-)-Phenylephrine hydrochloride
Target: Endogenous Metabolite, Adrenergic Receptor
Isoferulic acid
Cat.No: T2889
Synonym: Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸
Target: Influenza Virus, Adrenergic Receptor
Dronedarone
Cat.No: T7056
Synonym: 决奈达隆,SR 33589
Target: P450, Potassium Channel, Calcium Channel, Sodium Channel, Adrenergic Receptor, AChR, Autophagy
Methyldopa
Cat.No: T0505
Synonym: L-(-)-α-Methyldopa,MK-351,甲基多巴
Target: Dopamine Receptor, Adrenergic Receptor
Octopamine hydrochloride
Cat.No: T0469
Synonym: 章鱼胺盐酸盐,(±)-p-Octopamine hydrochlorid,(+,-)-Octopamine HCl,章胺盐酸盐
Target: Dopamine Receptor, Endogenous Metabolite, Adrenergic Receptor
β-Estradiol 17-acetate
Cat.No: T7299
Synonym: β-雌二醇 17-乙酸酯,17-乙酸-17-BETA-雌二酯,beta-estradiol 17-acetate,1,3,5(10)-Estratriene-3,17β-diol 17-acetate
Target: Estrogen Receptor/ERR, Others
Higenamine hydrochloride
Cat.No: T3232
Synonym: Higenamine HCl,Demethylcoclaurine hydrochloride,盐酸去甲乌头碱,norcoclaurine HCl,(+-)-Demethylcoclaurine hydrochloride,Higenamine Hydrochloride
Target: Adrenergic Receptor
Yohimbine
Cat.No: TCS2185
Synonym:
Target: Adrenergic Receptor
Norepinephrine bitartrate monohydrate
Cat.No: T1064
Synonym: 酒石酸去甲肾上腺素,Levophed,Noradrenaline bitartrate monohydrate,降肾上腺素
Target: Endogenous Metabolite, Adrenergic Receptor, Autophagy
Trimethylamine N-oxide dihydrate
Cat.No: T5247
Synonym: 二水氧化三甲胺,TMANO Dihydrate
Target: Others, Endogenous Metabolite
Rauwolscine hydrochloride
Cat.No: T4429
Synonym: Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride
Target: Adrenergic Receptor
Tolazoline hydrochloride
Cat.No: T1680
Synonym: Imidaline hydrochloride,苯甲唑啉盐酸盐,Imidaline (hydrochloride),Benzidazol hydrochloride,Tolazoline HCl,NSC35110 (hydrochloride)
Target: Adrenergic Receptor
Adrenosterone
Cat.No: T2207
Synonym: 肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G
Target: Androgen Receptor, Endogenous Metabolite
Estradiol
Cat.No: T1048
Synonym: 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
Genistin
Cat.No: T2882
Synonym: 染料木甙,Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside,染料木苷
Target: Apoptosis, Estrogen Receptor/ERR, Others
kaempferide
Cat.No: T3806
Synonym: Kaempferol 4'-O-methyl ether,山奈素,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Influenza Virus, Antibacterial, Autophagy
Anisodamine
Cat.No: T21532
Synonym: 6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine
Target: AChR
7-Amino-4-(trifluoromethyl)coumarin
Cat.No: TJS0341
Synonym: 香豆素151,Coumarin 151,AFC,7-氨基-4-(三氟甲基)香豆素
Target: 5-HT Receptor
2-Hydroxyanthraquinone
Cat.No: T36914
Synonym:
Target: Others
Isomucronulatol 7-O-glucoside
Cat.No: TN1787
Synonym: Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷
Target: Others
(-)-(S)-Equol
Cat.No: T6491
Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
Echistatin TFA
Cat.No: T36295
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-04717 CD122/IL2RB Protein, Rhesus, Recombinant (His)

interleukin 2 receptor, β,interleukin 2 recepto...

Rhesus HEK293 Cells
CD122/IL2RB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.1 kDa and the accession number is H9Z8K1.
TMPY-05102 CD122/IL2RB Protein, Rat, Recombinant (His)

interleukin 2 receptor, β,interleukin 2 recepto...

Rat HEK293 Cells
CD122/IL2RB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P26896.
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His)

TGFR-2,TGF-beta type II receptor,Transform...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPJ-00994 LTBR Protein, Mouse, Recombinant (hFc)

Tnfcr,Lymphotoxin-beta receptor,Tumor necr...

Mouse HEK293 Cells
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs...
TMPY-01767 IL-12RB2 Protein, Mouse, Recombinant (His)

A930027I18Rik,interleukin 12 receptor, beta

Mouse HEK293 Cells
IL-12RB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70 kDa and the accession number is P97378.
TMPY-05680 CD122/IL2RB Protein, Human, Recombinant (mFc)

CD122,IL15RB,IL-15RB,interleukin 2 receptor, be...

Human HEK293 Cells
CD122/IL2RB Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51 kDa and the accession number is P14784.
TMPY-01280 FOLR2 Protein, Human, Recombinant (His)

FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2...

Human HEK293 Cells
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPY-05216 CD122/IL2RB Protein, Human, Recombinant (His)

IL-15RB,interleukin 2 receptor, β,P70-75,IL15RB,int...

Human Baculovirus Insect Cells
CD122/IL2RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P14784.
TMPY-00860 CD122/IL2RB Protein, Human, Recombinant

interleukin 2 receptor, β,interleukin 2 recepto...

Human HEK293 Cells
CD122/IL2RB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is P14784.
TMPY-01701 IL-12RB1 Protein, Human, Recombinant (His)

interleukin 12 receptor, β1,IL12RB,IMD30,IL-12R-

Human HEK293 Cells
IL-12RB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is P42701-1.
TMPY-00476 ITGB1 Protein, Human, Recombinant (His)

VLAB,integrin, beta 1 (fibronectin receptor

Human HEK293 Cells
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe...
TMPY-05039 LTBR Protein, Human, Recombinant (hFc)

TNFR-RP,lymphotoxin β receptor (TNFR superfamily, m...

Human HEK293 Cells
LTBR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P36941-1.
TMPY-05784 CD122/IL2RB Protein, Mouse, Recombinant (hFc)

IL-15Rβ,Il-2/15Rbeta,Il-2Rβ,interleukin 2 recep...

Mouse HEK293 Cells
CD122/IL2RB Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.76 kDa and the accession number is P16297.
TMPY-04031 CD122/IL2RB Protein, Mouse, Recombinant (His)

IL-15Rβ,Il-2/15Rbeta,interleukin 2 receptor

Mouse HEK293 Cells
CD122/IL2RB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P16297.
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated

IFN-R,interferon (α, β and Ω) receptor 2,IFNABR,int...

Human HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-02647 IFNAR1 Protein, Human, Recombinant (His)

interferon (alpha, beta and omega) receptor

Human HEK293 Cells
IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1.
TMPJ-00113 CD79B Protein, Human, Recombinant (hFc)

Immunoglobulin-Associated B29 Protein,B-Cell-Specific Glycop...

Human HEK293 Cells
CD79B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-65 KDa and the accession number is P40259.
TMPY-01650 CD131 Protein, Human, Recombinant (His)

CDw131,IL5RB,colony stimulating factor 2 receptor, ...

Human HEK293 Cells
CD131 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is P32927-1.
TMPY-05157 TGFBR2 Protein, Human, Recombinant (His)

LDS2B,FAA3,TAAD2,MFS2,TGFR-2,TGFbeta-RII,transformi...

Human Baculovirus Insect Cells
TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
TMPY-01446 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)

IL-18Rbeta,CD218b,IL-18R β/IL-18RAP,IL-18Rβ,ACPL,IL...

Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is O95256-1.
TMPY-04716 CD122/IL2RB Protein, Rhesus, Recombinant (hFc)

interleukin 2 receptor, beta,interleukin 2...

Rhesus HEK293 Cells
CD122/IL2RB Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.4 kDa and the accession number is H9Z8K1.
TMPY-04712 IL-20RB Protein, Cynomolgus, Recombinant (His)

interleukin 20 receptor beta,interleukin 2...

Cynomolgus HEK293 Cells
IL-20RB Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is XP_005545913.1.
TMPY-04711 IL-20RB Protein, Cynomolgus, Recombinant (hFc)

interleukin 20 receptor β,interleukin 20 recept...

Cynomolgus HEK293 Cells
IL-20RB Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.2 kDa and the accession number is XP_005545913.1.
TMPY-04035 CD122/IL2RB Protein, Canine, Recombinant (hFc)

interleukin 2 receptor, beta,interleukin 2...

Canine HEK293 Cells
CD122/IL2RB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is XP_003431552.1.
TMPY-02902 IL-20RB Protein, Rat, Recombinant (His)

interleukin 20 receptor beta,interleukin 2...

Rat HEK293 Cells
IL-20RB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.6 kDa and the accession number is B8K1X9.
TMPY-05018 CD122/IL2RB Protein, Canine, Recombinant (His)

interleukin 2 receptor, beta,interleukin 2...

Canine HEK293 Cells
CD122/IL2RB Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is NP_001273779.1.
TMPY-03085 IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc)

interleukin 10 receptor, beta,interleukin ...

Rat HEK293 Cells
IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.7 kDa and the accession number is A6JLF1.
TMPY-03086 IL-20RB Protein, Rat, Recombinant (hFc)

interleukin 20 receptor beta,interleukin 2...

Rat HEK293 Cells
IL-20RB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.2 kDa and the accession number is B8K1X9.
TMPY-04562 GRK2 Protein, Human, Recombinant (His & GST)

β,adrenergic, beta, receptor kinase 1

Human Baculovirus Insect Cells
G-protein coupled receptor kinase 2 (GRK2), also referred as Adrenergic, beta, receptor kinase 1 (ADRBK1), is a ubiquitous member of the G protein-coupled receptor kinase (GRK) family that appears to play a central, integrative role in signal transduction cascades. GRK2 can phosphorylate a growing number of non-GPCR substrates and associate with a variety of proteins related to signal transduction, thus suggesting that this kinase could also have diverse 'effector' functions. GRK2 has been repor...
TMPJ-00326 CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

IL-2R subunit beta,High affinity IL-2 receptor<...

Human HEK293 Cells
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit c...
TMPY-06427 IL-12RB1 Protein, Cynomolgus, Recombinant (His)

interleukin 12 receptor, β1,interleukin 12 rece...

Cynomolgus HEK293 Cells
IL-12RB1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.98 kDa and the accession number is A0A2K5VWV1.
TMPY-06428 IL-12RB2 Protein, Cynomolgus, Recombinant (mFc)

interleukin 12 receptor, β2,interleukin 12 rece...

Cynomolgus HEK293 Cells
IL-12RB2 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 94.93 kDa and the accession number is XP_005543136.1.
TMPJ-00333 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

Transforming growth factor-β receptor type II,T...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
TMPH-01367 GABRB2 Protein, Human, Recombinant (His)

GABA(A) receptor subunit beta-2,GABRB2,Gam...

Human E. coli
GABRB2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.3 kDa and the accession number is P47870.
TMPY-03583 LTBR Protein, Rat, Recombinant (hFc)

lymphotoxin beta receptor (TNFR superfamil...

Rat HEK293 Cells
LTBR Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is Q5U2S8.
TMPY-04195 CHRNB3 Protein, Human, Recombinant (hFc)

cholinergic receptor, nicotinic, β 3 (neuronal),cho...

Human HEK293 Cells
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Prot...
TMPY-00554 CHRNB3 Protein, Human, Recombinant (His)

cholinergic receptor, nicotinic, beta 3 (n...

Human HEK293 Cells
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Prot...
TMPY-03252 LTBR Protein, Cynomolgus, Recombinant (hFc)

lymphotoxin β receptor (TNFR superfamily, member 3)...

Cynomolgus HEK293 Cells
LTBR Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.8 kDa and the accession number is F6V995.
TMPJ-00398 IL-12RB2 Protein, Mouse, Recombinant (hFc)

interleukin-12 receptor β-2 chain,IL-12RB2,interleu...

Mouse HEK293 Cells
The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits that are linked via disulfide bonds. Ligation of IL-12 to its receptor involves the binding of IL-12p35 to IL12RB1 and IL-12p40 to IL12RB2. This will result in the activation of tyrosine kinase 2 (TYK2), which is associated with the IL12RB1 chain and Janus kinase 2 (JAK2), which is ...
TMPJ-00334 TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)

TGF-β receptor type II,Tgfbr2,TGF-β receptor

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.
TMPH-01537 ITGB7 Protein, Human, Recombinant (His)

Integrin beta-7,ITGB7,Gut homing receptor ...

Human E. coli
ITGB7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 82.5 kDa and the accession number is P26010.
TMPY-02771 LTBR Protein, Rat, Recombinant (His)

lymphotoxin beta receptor (TNFR superfamil...

Rat HEK293 Cells
LTBR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23 kDa and the accession number is Q5U2S8.
TMPH-03114 ITGB1 Protein, Pig, Recombinant (His & Myc)

VLA-4 subunit beta,Integrin beta-1,Fibrone...

Sus scrofa (Pig) E. coli
ITGB1 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.1 kDa and the accession number is Q9GLP0.
TMPY-00385 PDGFRB Protein, Rhesus, Recombinant (hFc)

platelet-derived growth factor receptor, β polypept...

Rhesus HEK293 Cells
PDGFRB Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.3 kDa and the accession number is F7BTH1.
TMPY-03590 PDGFRB Protein, Rhesus, Recombinant (His)

platelet-derived growth factor receptor, β polypept...

Rhesus HEK293 Cells
PDGFRB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is F7BTH1.
TMPY-05465 IL-20RB Protein, Mouse, Recombinant (His)

Fndc6,Gm186,Il20R2,interleukin 20 receptor β,AV2280...

Mouse HEK293 Cells
IL-20RB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is E9Q9A6.
TMPY-03474 PDGFRB Protein, Rat, Recombinant (hFc)

platelet-derived growth factor receptor, β polypept...

Rat HEK293 Cells
PDGFRB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number is Q05030.
TMPY-03140 PDGFRB Protein, Rat, Recombinant (His)

platelet-derived growth factor receptor, beta

Rat HEK293 Cells
PDGFRB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is Q05030.
TMPJ-00363 IL-12RB1 Protein, Human, Recombinant (hFc)

IL-12R-β1,IL-12R-BETA1,IL-12 receptor subu...

Human HEK293 Cells
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL...
TMPY-03649 TGFBR3 Protein, Human, Recombinant (His)

βglycan,betaglycan,transforming growth factor, ...

Human Baculovirus Insect Cells
TGFBR3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42.2 kDa and the accession number is Q03167-1.
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重组蛋白

CD122/IL2RB Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-04717
Species: Rhesus
Expression System: HEK293 Cells
CD122/IL2RB Protein, Rat, Recombinant (His)
Cat.No: TMPY-05102
Species: Rat
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00335
Species: Mouse
Expression System: HEK293 Cells
LTBR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00994
Species: Mouse
Expression System: HEK293 Cells
IL-12RB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01767
Species: Mouse
Expression System: HEK293 Cells
CD122/IL2RB Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05680
Species: Human
Expression System: HEK293 Cells
FOLR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01280
Species: Human
Expression System: HEK293 Cells
CD122/IL2RB Protein, Human, Recombinant (His)
Cat.No: TMPY-05216
Species: Human
Expression System: Baculovirus Insect Cells
CD122/IL2RB Protein, Human, Recombinant
Cat.No: TMPY-00860
Species: Human
Expression System: HEK293 Cells
IL-12RB1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01701
Species: Human
Expression System: HEK293 Cells
ITGB1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00476
Species: Human
Expression System: HEK293 Cells
LTBR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05039
Species: Human
Expression System: HEK293 Cells
CD122/IL2RB Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05784
Species: Mouse
Expression System: HEK293 Cells
CD122/IL2RB Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04031
Species: Mouse
Expression System: HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04799
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02647
Species: Human
Expression System: HEK293 Cells
CD79B Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00113
Species: Human
Expression System: HEK293 Cells
CD131 Protein, Human, Recombinant (His)
Cat.No: TMPY-01650
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-05157
Species: Human
Expression System: Baculovirus Insect Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)
Cat.No: TMPY-01446
Species: Human
Expression System: HEK293 Cells
CD122/IL2RB Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-04716
Species: Rhesus
Expression System: HEK293 Cells
IL-20RB Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-04712
Species: Cynomolgus
Expression System: HEK293 Cells
IL-20RB Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-04711
Species: Cynomolgus
Expression System: HEK293 Cells
CD122/IL2RB Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-04035
Species: Canine
Expression System: HEK293 Cells
IL-20RB Protein, Rat, Recombinant (His)
Cat.No: TMPY-02902
Species: Rat
Expression System: HEK293 Cells
CD122/IL2RB Protein, Canine, Recombinant (His)
Cat.No: TMPY-05018
Species: Canine
Expression System: HEK293 Cells
IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03085
Species: Rat
Expression System: HEK293 Cells
IL-20RB Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03086
Species: Rat
Expression System: HEK293 Cells
GRK2 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04562
Species: Human
Expression System: Baculovirus Insect Cells
CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated
Cat.No: TMPJ-00326
Species: Human
Expression System: HEK293 Cells
IL-12RB1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-06427
Species: Cynomolgus
Expression System: HEK293 Cells
IL-12RB2 Protein, Cynomolgus, Recombinant (mFc)
Cat.No: TMPY-06428
Species: Cynomolgus
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
Cat.No: TMPJ-00333
Species: Mouse
Expression System: HEK293 Cells
GABRB2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01367
Species: Human
Expression System: E. coli
LTBR Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03583
Species: Rat
Expression System: HEK293 Cells
CHRNB3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04195
Species: Human
Expression System: HEK293 Cells
CHRNB3 Protein, Human, Recombinant (His)
Cat.No: TMPY-00554
Species: Human
Expression System: HEK293 Cells
LTBR Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-03252
Species: Cynomolgus
Expression System: HEK293 Cells
IL-12RB2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00398
Species: Mouse
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
Cat.No: TMPJ-00334
Species: Mouse
Expression System: HEK293 Cells
ITGB7 Protein, Human, Recombinant (His)
Cat.No: TMPH-01537
Species: Human
Expression System: E. coli
LTBR Protein, Rat, Recombinant (His)
Cat.No: TMPY-02771
Species: Rat
Expression System: HEK293 Cells
ITGB1 Protein, Pig, Recombinant (His & Myc)
Cat.No: TMPH-03114
Species: Sus scrofa (Pig)
Expression System: E. coli
PDGFRB Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-00385
Species: Rhesus
Expression System: HEK293 Cells
PDGFRB Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-03590
Species: Rhesus
Expression System: HEK293 Cells
IL-20RB Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05465
Species: Mouse
Expression System: HEK293 Cells
PDGFRB Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03474
Species: Rat
Expression System: HEK293 Cells
PDGFRB Protein, Rat, Recombinant (His)
Cat.No: TMPY-03140
Species: Rat
Expression System: HEK293 Cells
IL-12RB1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00363
Species: Human
Expression System: HEK293 Cells
TGFBR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03649
Species: Human
Expression System: Baculovirus Insect Cells
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Cat. No. Product Name Target Signaling Pathways
T14687 Deucravacitinib

BMS-986165

Tyrosine Kinases; JAK; IFNAR; Interleukin Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂,用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活,可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域,IC50为1.0 nM。
TMIJ-0175 Bisoprolol-d5 Hemifumarate

Bisoprolol-d5 Hemifumarate 是 Bisoprolol Hemifumarate 的氘代化合物。Bisoprolol Hemifumarate 的 CAS 号为 104344-23-2。Bisoprolol hemifumarate 是一种 β1 肾上腺素受体阻断剂。
TMID-0236 Bisoprolol-d7 hemifumarate

Bisoprolol-d7 hemifumarate 是 Bisoprolol hemifumarate 的氘代化合物。Bisoprolol hemifumarate 的 CAS 号为 104344-23-2。Bisoprolol hemifumarate 是一种 β1 肾上腺素受体阻断剂。
TMIJ-0317 Nadolol-d9 (Mixture of Diastereomers)

Nadolol-d9 (Mixture of Diastereomers) 是 Nadolol 的氘代化合物。Nadolol 的 CAS 号为 42200-33-9。Nadolol 是一种有机阴离子转运多肽 1A2 (OATP1A2) 的底物,是一种非选择性的、具有口服活性的 β-肾上腺素受体 (β-adrenergic receptors) 阻滞剂,可用于高血压,心绞痛和血管性头痛的研究。
TMID-0115 Dehydroepiandrosterone-2,2,3,4,4,6-d6

DHEA-d6

Dehydroepiandrosterone-2,2,3,4,4,6-d6 是 Dehydroepiandrosterone 的氘代化合物。Dehydroepiandrosterone 的 CAS 号为 53-43-0。Dehydroepiandrosterone 是一种类固醇激素。它通过多种信号传导途径介导其作用,并通过转化成雄激素和雌激素衍生物(例如,雄激素,雌激素,7α和7β DHEA (Prasterone),以及7α和7β表雄甾酮衍生物)在特异性受体上起作用。

同位素标记化合物

Deucravacitinib
Cat.No: T14687
Synonym: BMS-986165
Target: Tyrosine Kinases, JAK, IFNAR, Interleukin
Bisoprolol-d5 Hemifumarate
Cat.No: TMIJ-0175
Synonym:
Target:
Bisoprolol-d7 hemifumarate
Cat.No: TMID-0236
Synonym:
Target:
Nadolol-d9 (Mixture of Diastereomers)
Cat.No: TMIJ-0317
Synonym:
Target:
Dehydroepiandrosterone-2,2,3,4,4,6-d6
Cat.No: TMID-0115
Synonym: DHEA-d6
Target:
TargetMol Loading
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