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Cat. No. | Product Name | ||
---|---|---|---|
L9810 | 抗纤维化化合物库 | 1180 compounds | |
1180 种潜在的抗纤维化分子,是研究纤维化的有效工具,可以用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6019 |
Volasertib
BI 6727,伏拉塞替 |
Apoptosis; PLK | Apoptosis; Cell Cycle/Checkpoint |
Volasertib (BI 6727) 是一种具有口服活性的高效ATP 竞争性Polo 样激酶 1 抑制剂。它抑制 PLK2 和 PLK3,IC50分别为 5 和 56 nM。它是二氢蝶呤酮衍生物,有抗肿瘤活性,可诱导有丝分裂停滞和细胞凋亡。 | |||
T90421 |
2-Bromo-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridine
|
||
2-Bromo-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridine 是有一种有用的有机化合物,已被用于生命科学相关研究。 | |||
T9607 |
2-Thiopheneacetamide, α-[(2-bromoacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-
|
||
2-Thiopheneacetamide, α-[(2-bromoacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)- 在生命科学相关研究中具有广泛的应用。 | |||
T0880 |
Bronopol
布波尔,BNPK,溴硝醇,BNPD |
Antibacterial | Microbiology/Virology |
Bronopol (BNPD) 是一种抗菌剂,对哺乳动物毒性低和对革兰氏阴性菌活性高。 | |||
T2188 |
Thonzonium Bromide
嘧苯十六铵,通佐溴胺 |
Proton pump; Antibacterial; Autophagy | Autophagy; Membrane transporter/Ion channel; Microbiology/Virology |
Thonzonium bromide 是一种单阳离子表面活性剂,在结构上与 Farnesol 相似的抗菌剂。它以剂量依赖的方式抑制质子转运 (EC50=69 μM)。在体外可抑制 RANKL 诱导的破骨细胞形成和骨吸收,并在体内阻止 LPS 诱导的骨丢失。 | |||
T0920 |
Ambroxol
氨溴索,氨溴索碱,Ambroxolum,NA-872 |
P450; Autophagy | Autophagy; Metabolism |
Ambroxol (NA-872) 是前药溴己辛的活性代谢产物,是一种分泌溶解剂,具有强效祛痰作用,用于治疗与粘液或过多粘液相关的呼吸道疾病。它可诱导肺组织细胞自噬,有用于帕金森氏病和神经性戈谢病的研究潜力。它是一种葡糖脑苷脂酶伴侣,可增加葡糖脑苷脂酶的活性。 | |||
T10295 |
Amantanium bromide
金刚溴铵,Amantanil bromidum |
Others | Others |
Amantanium bromide (Amantanil bromidum) 是一种季铵抗菌/抗真菌剂,可用作手术防腐剂以及粘液和皮肤感染的局部治疗。 | |||
T22761 |
EIT hydrobromide
2-Ethyl-2-thiopseudourea hydrobromide,S-Ethylisothiourea hydrobromide,S-乙基硫酸乙烯溴化氢 |
NOS | Immunology/Inflammation |
EIT hydrobromide (S-Ethylisothiourea hydrobromide) 是一种iNOS 抑制剂。 | |||
T14797 |
Bromo-PEG3-C2-acid
溴代-三聚乙二醇-羧酸 |
PROTAC Linker | PROTAC |
Bromo-PEG3-C2-acid 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T2403 |
Bromfenac sodium hydrate
Bromfenac sodium,Bromfenac monosodium salt sesquihydrate,溴芬酸钠 |
COX | Immunology/Inflammation; Neuroscience |
Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) 是一种可口服的 COX 抑制剂,抑制 COX-1和COX-2的IC50值分别为 5.56 和 7.45 nM。它是一种溴化非甾体类抗炎药,有用于白内障的术后炎症和疼痛以及假晶状体囊状黄斑水肿的研究。 | |||
T17321 |
1,3-Dibromo-5,5-dimethylhydantoin
|
Others; PROTAC Linker | Others; PROTAC |
1,3-Dibromo-5,5-dimethylhydantoin 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T16471 |
Perflubron
Perfluorooctyl bromide,全氟溴辛烷,PFOB |
Others | Others |
Perflubron (Perfluorooctyl bromide) 是一种用于磁共振成像和超声检查的造影剂,可以与卵磷脂(EYP)一起乳化,并表现出较迅速的排泄特性。 | |||
T7543 |
S-(2-aminoethyl) Isothiourea (dihydrobromide)
|
NOS | Immunology/Inflammation |
S-(2-aminoethyl) Isothiourea (dihydrobromide) 是所有 NOS 异构体的非选择性抑制剂。对于人类 nNOS、eNOS 和 iNOS,Ki 值分别为 1.8、2.1 和 0.59 µM。 | |||
T2707 |
Pifithrin-α hydrobromide
Pifithrin hydrobromide,Pifithrin-α (PFTα) HBr,Pifithrin-α,PFTα,PFTα hydrobromide |
Ferroptosis; Aryl Hydrocarbon Receptor; p53 | Apoptosis; Immunology/Inflammation |
Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) 是一种 p53 抑制剂,可抑制 p53 反应基因的 p53 依赖性反式激活。它也是芳烃受体的激动剂。 | |||
T7832 |
Ibrolipim
NO-1886 |
LPL Receptor | GPCR/G Protein |
Ibrolipim (NO-1886) 是口服具有活力的脂蛋白脂肪酶 (LPL) 激活剂。它能够降低血浆甘油三酸酯,增加高密度脂蛋白胆固醇水平,具有肾保护和降血脂的作用。 | |||
T7206L |
2-Iminobiotin hydrobromide
2-亚氨基生物素,Guanidinobiotin,2-亚氨基生物素盐酸盐 |
NOS; NO Synthase | Immunology/Inflammation |
2-Iminobiotin hydrobromide (Guanidinobiotin) 是生物素 (维生素 H 或 B7) 类似物。它是一种可逆的 NO 合酶抑制剂,可作用于小鼠 iNOS(Ki:21.8 μM)和大鼠 n-cNOS(Ki:37.5 μM)。它和低温环境均可以保护人类神经细胞,使其免受缺氧诱导的细胞损伤。 | |||
T14830 |
Bromperidol
溴哌利多,R-11333 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Bromperidol (R-11333) 是一种苯丁酮衍生物,是一种强效长效精神安定药。它被用作治疗精神分裂症的抗精神病药。 | |||
T5882 |
3-Bromopyruvic acid
Hexokinase II Inhibitor II, 3-BP,3-溴丙酮酸,Bromopyruvic acid |
Apoptosis; Hexokinase; Autophagy | Apoptosis; Autophagy; Metabolism |
3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) 是己糖激酶 II 抑制剂,是针对肝癌细胞的一种抗肿瘤剂。 | |||
T10717 |
Inobrodib
CBP-IN-1 |
Epigenetic Reader Domain | Chromatin/Epigenetic |
Inobrodib (CBP-IN-1) 是一种口服活性的强选择性p300/CBP 抑制剂,与 p300 和 CBP 结合,Kd 值为 1.3 和 1.7 nM。它抑制前列腺癌细胞系的细胞增殖并降低雄激素受体和 C-MYC 调节的基因表达。 | |||
T0023 |
Valethamate bromide
Ediposin,Epidozin,戊沙溴铵,Epidosin,Resitan |
Others | Others |
Valethamate bromide (Resitan) 是快速作用的抗胆碱能解痉和肌萎缩剂,是一种酯,能够改善宫颈扩张加速分娩。 | |||
T0166 |
Pancuronium dibromide
Pancuronium bromide,Pavulon,泮库溴铵 |
AChR | Neuroscience |
Pancuronium dibromide (Pavulon) 是一种双季基类固醇,是一种神经肌肉松弛剂。它通过与乙酰胆碱竞争 nACh 受体上的结合位点来抑制神经肌肉传递。它还可抑制心脏毒蕈碱受体并具有拟交感神经作用。 | |||
T23524 |
W-84 dibromide
HDMPPA |
AChR | Neuroscience |
W-84 dibromide (HDMPPA) 是 M2胆碱受体的强变构调节剂,是一种非竞争性毒蕈碱乙酰胆碱受体拮抗剂,具有变构效应。它联合阿托品时,可有效地防止有机磷中毒。它阻碍 [3H]N-甲基东莨菪碱解离,能稳定胆碱能拮抗剂-受体复合物。 | |||
T22534 |
8-Hydroxy-DPAT hydrobromide
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐,8-OH-DPAT hydrobromide |
5-HT Receptor | GPCR/G Protein; Neuroscience |
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) 是一种选择性5-HT1A 激动剂,pIC50为 8.19。它对 5-HT1结合位点的亚型有近 1000 倍的选择性。 | |||
T21685 |
CCT 031374 hydrobromide
|
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
CCT 031374 hydrobromide 是一种 TCF/β-catenin 抑制剂,具有抗肿瘤活性。 | |||
T5842 |
Bromocriptine mesylate
甲磺酸溴隐亭,CB-154 |
Dopamine Receptor; Autophagy | Autophagy; GPCR/G Protein; Neuroscience |
Bromocriptine mesylate (CB-154) 是一种有效的多巴胺受体激动剂,以最高的亲和力结合 D2 受体,Ki 为 2.5 nM。 | |||
T0427 |
Homatropine Methylbromide
Homatropine methobromide,溴甲基后马托品 |
AChR | Neuroscience |
Homatropine Methylbromide 是一种毒蕈碱受体 AChR 拮抗剂,抑制 WKY-E 和 SHR-E ,IC50分别为 162.5 和 170.3 nM。 | |||
T4981 |
Anisotropine Methylbromide
|
Prostaglandin Receptor; AChR | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Anisotropine Methylbromide 是一种抗胆碱能药物,已用于缓解胃肠道痉挛和抑制胃酸分泌。 | |||
T9858 |
5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole
|
Parasite | Microbiology/Virology |
Antileishmanial agent-2 是一种基于 3-Br-isoxazoline 的疟原虫抑制剂恶性疟原虫(D10 和 W2 菌株)和利什曼原虫属。 (L. infantum 和 L.tropica) 前鞭毛体,IC50 为 0.035、0.058、3.5 和 7.5 μM。 | |||
T10108 |
3-Bromocytisine
(-)-3-Bromocytisine,(-)-9-Bromocytisine,3-Br-cytisine |
AChR | Neuroscience |
3-Bromocytisine ((-)-3-Bromocytisine) 是一种有效的 nAChR 激动剂,对 hα4β4、hα4β2 和 hα7 的 IC50值分别为0.28、0.30 和 31.6 nM。 | |||
T15195 |
Ebrotidine
FI3542,乙溴替丁 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Ebrotidine (FI3542) 是有效的、竞争性的H2受体的拮抗剂,Ki 为127.5nM。Ebrotidine 具有抗分泌活性,可用于胃保护。 | |||
T7454 |
4-Bromo-3-hydroxybenzoic acid
|
Decarboxylase; Endogenous Metabolite | Metabolism; Others |
4-Bromo-3-hydroxybenzoic acid 是一种组氨酸脱羧酶抑制剂,是一种 Brocresine 的代谢产物,对大鼠胎儿和大鼠胃HDC 的IC50均为 1 mM。它还能够在体外抑制猪肾脏和大鼠胃粘膜中的芳香族 L-氨基酸脱羧酶,两种酶的IC50均为 1 mM。 | |||
T0807 |
Tribromoethyl alcohol
2,2,2-Tribromoethanol,Avertin,Basibrol,Tribromoethanol,三溴乙醇,TBE |
Others | Others |
Tribromoethyl alcohol (Avertin) 具有麻醉活性,常被用作实验动物的麻醉剂,尤其是啮齿类动物。Tribromoethyl alcohol 的麻醉时间短,麻醉起效快。 | |||
T18929 |
Bromobimane
Monobromobimane |
Autophagy | Autophagy |
Bromobimane (Monobromobimane) 是一种非荧光物质,但与硫醇反应反应时生成荧光产物。Bromobimane 可被当作一种探针使用,常在临床医学上检验血液中硫化物的含量。 | |||
TP1153L |
Fibronectin Adhesion-promoting Peptide acetate
Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate |
Others | Others |
Fibronectin Adhesion-promoting Peptide acetate (Heparin Binding Peptide acetate)(125720-21-0 free base) 是在纤连蛋白的羧基末端肝素结合结构域中发现的肝素结合氨基酸序列之一。 | |||
TP1555L1 |
Fibronectin Active Fragment Control acetate
Fibronectin Active Fragment Control acetate(97461-84-2 Free base) |
||
Fibronectin Active Fragment Control acetate 是纤连蛋白的活性片段,这是一种糖蛋白。 | |||
T13720 |
Hexadimethrine bromide
1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide,海美溴铵,聚凝胺,Polybrene |
Others | Others |
Hexadimethrine bromide (Polybrene) 是一种阳离子聚合物,可以用于逆转录病毒和慢病毒感染,提高基因转移效率。 | |||
T5111 |
4-Bromomethyl-2-cyanobiphenyl
|
Others | Others |
4-Bromomethyl-2-cyanobiphenyl 是一种卤代苯甲腈,用于喹喔啉血管紧张素 II 受体拮抗剂的蛋白质结合研究。 | |||
T16218 |
N-Boc-PEG5-bromide
|
Others; PROTAC Linker; ADC Linker | Antibody-drug Conjugate/ADC Related; Others; PROTAC |
N-Boc-PEG5-bromide 是 PROTAC 的 linker,属于 PEG 类和 Alkyl/ether 类.它也是可降解的 ADC 连接桥,用于抗体药物结合物的合成。 | |||
T60017 |
5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside
|
Others | Others |
5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside 是用于检测纤维生物水解酶的显色化合物。 | |||
T76779 |
Brodalumab
LP 0160,KHK-4827,AMG-827 |
IL Receptor | Immunology/Inflammation |
Brodalumab (AMG 827) 是一种人源靶向白介素 17 受体 (IL-17R) IgG2 的单克隆抗体,常作为免疫抑制剂来治疗银屑病和牛皮藓。 | |||
T13919 |
Terbufibrol
|
Others | Others |
Terbufibrol 降低正常和高胆固醇血症雄性大鼠的血清总胆固醇水平。 | |||
T21422 |
Methylnaltrexone bromide
Relistor,MOA-728,MOA 728,Methylnaltrexone,溴化甲基纳曲酮,MOA728 |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Methylnaltrexone bromide (MOA-728) 是纳曲酮的四元衍生物,是可口服的外周作用 μ 阿片拮抗剂。它穿越血脑屏障的能力有限,可在胃肠道组织中发挥作用。 | |||
T5351L |
PU-WS13 hydrobromide
PU-WS13 hydrobromide (1454619-14-7 Free base) |
GPR | Endocrinology/Hormones; GPCR/G Protein |
PU-WS13 hydrobromide 是一种 GRP94 抑制剂,具有抗炎活性,对小鼠 TNBC 肿瘤中的 M2 样巨噬细胞的增殖具有抑制作用。 | |||
T40363 |
Poly-D-lysine hydrobromide (MW 30000-70000)
Poly-D-lysine HBr (MW 30000-70000) |
CaSR | GPCR/G Protein |
Poly-D-lysine hydrobromide (MW 30000-70000)(Poly-D-lysine HBr) 是一种可口服的肽类 CaSR 激动剂,可从朊病毒感染的 SN56 神经母细胞瘤细胞中去除蛋白酶 K 抗性的 PrP。 | |||
T21788 |
BD 1008 dihydrobromide
|
Sigma receptor | GPCR/G Protein |
BD 1008 dihydrobromide 是 sigma 1 (σ1) 受体 (Ki = 2 nM) 的选择性拮抗剂。 它对 sigma1 受体具有高亲和力,对 sigma2 受体具有中等亲和力。 它通过拮抗 σ 受体减弱可卡因的毒性和刺激作用。 | |||
T50066 |
1-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide
|
AChE | Neuroscience |
1-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide 是人类红细胞 AChE 的抑制剂。 | |||
T0287 |
Hexamethonium Bromide
Gangliostat,溴化六甲铵,Simpatoblock,六甲溴铵,Hexamethonium Dibromide |
Apoptosis; Dopamine Receptor; AChR | Apoptosis; GPCR/G Protein; Neuroscience |
Hexamethonium Bromide (Hexamethonium Dibromide) 是神经节中神经元型烟碱型 AChR 的特异性拮抗剂。在自发性高血压动物模型中,它能降低其交感神经活动和血压。 | |||
T1230 |
Pamabrom
巴马溴,帕马溴 |
Others | Others |
Pamabrom 是一种利尿剂,有效成分为8-bromotheophylline,能够缓解月经相关症状。 | |||
T9420 |
prifinium bromide
|
Others | Others |
Prifinium bromide 是抗胆碱能试剂,能够改善痉挛,具有止吐效果。 | |||
TD0105 |
Sulfobromophthalein disodium salt
|
Others | Others |
Sulfobromophthalein disodium salt 是一种有机阴离子染料,能够参与药物和代谢物的运输,可用于研究动物组织中表达的多种膜载体。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN7171 |
2,4,6-tribromobenzene-1,3,5-triol
三溴间苯三酚,2,4,6-Tribromophloroglucinol,1,3,5-Benzenetriol, 2,4,6-tribromo- (9CI),Tribromophloroglucinol |
Others | Others |
2,4,6-tribromobenzene-1,3,5-triol (1,3,5-Benzenetriol, 2,4,6-tribromo- (9CI)) 是一种海洋来源的天然产物,存在于Rhabdonia verticillata。 | |||
TN7174 |
methyl 5-bromo-1H-pyrrole-2-carboxylate
甲基 5-溴-1H-吡咯-2-甲酸酯,ZINC13379818 |
Others | Others |
methyl 5-bromo-1H-pyrrole-2-carboxylate 是一种海洋来源的天然产物,存在于Lissodendoryx sp.。 | |||
TN7184 |
5,6-dibromo-1H-indole-3-carbaldehyde
ZINC198368276,5,6-二溴吲哚-3-甲醛 |
Others | Others |
5,6-dibromo-1H-indole-3-carbaldehyde 是一种海洋来源的天然产物,存在于Smenospongia sp.。 | |||
TN7202 |
3-Chloro-6-Bromo Indole
6-溴-3-氯-1H-吲哚,6-bromo-3-chloro-1H-indole,3-CHLORO-6-BROMOINDOLE |
Others | Others |
3-Chloro-6-Bromo Indole (3-CHLORO-6-BROMOINDOLE) 是一种海洋来源的天然产物,存在于 Ptychodera flava。 | |||
TN7188 |
2-broMobenzene-1,3,5-triol
2-bromo-phloroglucinol,1,3,5-三羟基2-溴苯,Bromophloroglucinol,2-Bromo-1,3,5-benzenetriol |
Others | Others |
2-broMobenzene-1,3,5-triol (Bromophloroglucinol) 是一种海洋来源的天然产物,发现于 Rhabdonia verticillata。 | |||
TN7187 |
2,4-dibroMobenzene-1,3,5-triol
2,4-dibromophloroglucinol,1,3,5-三羟基2,4-二溴苯,2,4-Dibromo-1,3,5-benzenetriol |
Others | Others |
2,4-dibroMobenzene-1,3,5-triol (2,4-Dibromo-1,3,5-benzenetriol) 是一种海洋来源的天然产物,存在于Rhabdonia verticillata。 | |||
TN7167 |
2,4,5-Tribromoimidazole
2,4,5-三溴咪唑,2,4,5-Tribromo-1H-imidazole |
Others | Others |
2,4,5-Tribromoimidazole (2,4,5-Tribromo-1H-imidazole) 是一种海洋来源的天然产物,存在于 Hexaplex trunculus。 | |||
TN7165 |
3,6-Dibromocarbazole
3,6-Dibromo-9H-carbazole,3,6二溴咔唑 |
Others | Others |
3,6-Dibromocarbazole (3,6-Dibromo-9H-carbazole) 是一种海洋来源的天然产物,存在于Kyrtuthrix maculans。 | |||
TN1691 |
Glabrol
光甘草酚,光甘草醇 |
P450; NF-κB; NO Synthase; Acyltransferase | Immunology/Inflammation; Metabolism; NF-κB |
Glabrol 是分离自甘草根的乙醇提取物中的一种异戊二烯类黄酮,是一种有效且非竞争性的酰基辅酶 A:胆固醇酰基转移酶(ACAT)抑制剂,抑制大鼠肝脏微粒体 ACAT 的IC50为 24.6 μM。 | |||
T8304 |
Anisodamine Hydrobromide
6-Hydroxyhyoscyamine,氢溴酸山莨菪碱 |
Adrenergic Receptor; AChR | GPCR/G Protein; Neuroscience |
Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) 是来自颠茄的一种生物碱,具有抗氧化、抗炎活性。它也是一种非亚型的选择性毒蕈碱和烟碱类胆碱受体拮抗剂。 | |||
T13514 |
5-MethoxyPinocembroside
|
Others | Others |
5-MethoxyPinocembroside 是一种黄酮类天然产物,存在于辣木 Moringa oleifera 的叶子中。 | |||
TN1114 |
Carabrone
|
Antibacterial; Antifection | Microbiology/Virology |
Carabrone 是分离自Carpesium abrotanoides 果实的一种倍半萜,表现出显著抗肿瘤活性和抗菌活性,如灰霉病菌Botrytis cinerea,炭疽病菌Colletotrichum lagenarium 和禾白粉菌Erysiphe graminis。 | |||
T18930 |
Bromothymol Blue
|
Others | Others |
Bromothymol Blue 是 pH 指示剂,在测定弱酸弱碱时使用,在酸性条件下为黄色,在碱性条件下为蓝色。 | |||
T7924 |
8-Bromoguanosine
|
Others | Others |
8-Bromoguanosine 是鸟苷的溴化衍生物。它是通过细胞内机制激活淋巴细胞发挥免疫刺激作用。 | |||
TN1693 |
Glabrone
|
Influenza Virus; PPAR | DNA Damage/DNA Repair; Metabolism; Microbiology/Virology |
Glabrone 是从甘草根中分离的一种异黄酮,可与 PPAR-γ 配体结合,具有抗流感活性。 | |||
TN7223 |
3,5-Dibromo-4-methoxybenzoic acid
|
Others | Others |
3,5-Dibromo-4-methoxybenzoic acid 是从马达加斯加海绵 Amphimedon sp.中分离出的化合物,可用于合成其他化合物。 | |||
T6560 |
Lappaconitine hydrobromide
氢溴酸高乌甲素,Lappaconite HBr,Allapinine |
Others | Others |
Lappaconitine hydrobromide (Allapinine) 是天然生物碱类化合物,具有抗心律失常作用。 | |||
T4962 |
Zingibroside R1
Ginsenoside Z-R1,姜状三七皂苷R1,姜状三七苷R1 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Zingibroside R1 (Ginsenoside Z-R1) 是分离自Panax japonicasC. A. Meyer 根部的一种三萜皂苷,有HIV-1、抗肿瘤和抗血管生成活性。它对 EAT 细胞的 2-脱氧-D-葡萄糖的摄取具有抑制作用,IC50值为91.3 μM。 | |||
T38022 |
2,6-Dibromophenol
2,6-Dibromo-phenol,2,6-二溴苯酚 |
Endogenous Metabolite | Metabolism |
2,6-Dibromophenol (2,6-Dibromo-phenol) 从比目鱼的皮肤和肌肉中提取。 | |||
TN7197 |
6-Chloro-2,4-dibromophenol
2,4-dibromo-6-chloro-phenol,2,4-二溴-6-氯苯酚,2,4-dibromo-6-chlorophenol,ZINC397569 |
Others | Others |
6-Chloro-2,4-dibromophenol (2,4-dibromo-6-chlorophenol) 是一种海洋来源的天然产物,存在于Pseudoalteromonas luteoviolacea。 | |||
TN7183 |
6-Bromo-1H-indole-3-acetic acid methyl ester
Methyl 2-(6-bromo-1H-indol-3-yl)acetate,Methyl 6-Bromoindole-3-acetate,6-溴-1H-吲哚-3-乙酸甲酯 |
Others | Others |
6-Bromo-1H-indole-3-acetic acid methyl ester (Methyl 6-Bromoindole-3-acetate) 是一种海洋来源的天然产物,存在于Pseudosuberites hyalinus。 | |||
TN7172 |
4,5-Dibromo-1H-Pyrrole-2-Carboxylic Acid
5-溴-1H-吡咯-2-羧酸,4,5-Dibromo-2-pyrrolic acid,4,5-dibromopyrrole-2-carboxylic acid |
Others | Others |
4,5-Dibromo-1H-Pyrrole-2-Carboxylic Acid (4,5-Dibromo-2-pyrrolic acid) 是一种海洋来源的天然产物,存在于Agelas oroides。 | |||
TN7161 |
2,3-Dibromomaleinimide
3,4-dibromo-1h-pyrrole-2,5-dione,3,4-Dibromopyrrole-2,5-dione,3,4-二溴-1H-吡咯-2,5-二酮 |
Others | Others |
2,3-Dibromomaleinimide (3,4-Dibromopyrrole-2,5-dione) 是一种海洋来源的天然产物,存在于Axinella brevistyla。 | |||
TN7166 |
2,4,6-Tribromophenol
Bromol,2,4,6-三溴苯酚,Xeroform,Tribromophenol |
Others | Others |
2,4,6-Tribromophenol (Bromol) 是一种海洋来源的天然产物,存在于Phoronopsis harmeri。 | |||
TN7191 |
4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine
4-氨基-5-溴吡咯并[2,3-D]嘧啶,5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Others | Others |
4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine (5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine) 是一种海洋来源的天然产物,存在于Echinodictyum sp.。 | |||
T36581 |
Glucocerebrosides
|
Others | Others |
Glucocerebrosides 是一种天然产物。 | |||
TN7162 |
3-Bromobenzoic acid
m-Bromobenzoic acid,3-Bromo-benzoic acid,3-溴苯甲酸,3-Bromobenzoicacid |
Others | Others |
3-Bromobenzoic acid (m-Bromobenzoic acid) 是一种海洋来源的天然产物,存在于Tubastraea micranthus。 | |||
T2198 |
Arecoline hydrobromide
Arecoline HBr,氢溴酸槟榔碱,Arecoline bromide |
AChR | Neuroscience |
Arecoline hydrobromide (Arecoline HBr) 是从槟榔中得到的一种生物碱,具有刺激、警觉、抗焦虑和抗寄生虫作用。它是烟碱和毒蕈碱乙酰胆碱受体的部分激动剂,可诱导氧化应激。 | |||
TN7186 |
Methyl 6-bromo-1H-indole-3-carboxylate
Methyl 6-bromo-1H-indole-3-carboxylate,6-溴吲哚-3-羧酸甲酯 |
Others | Others |
1H-Indole-3-Carboxylic Acid,6-Bromo-,Methyl Ester (Methyl 6-bromo-1H-indole-3-carboxylate) 是一种海洋来源的天然产物,存在于 Smenospongia sp.。 | |||
TN7135 |
2-(3,5-dibromo-4-methoxyphenyl)acetic acid
3,5-Dibromo-4-methoxybenzeneacetic acid,3,5-dibromo-4-methoxy-phenylacetic acid,3,5-Dibromo-4-methoxyphenyl acetic acid |
Others | Others |
2-(3,5-dibromo-4-methoxyphenyl)acetic acid (3,5-Dibromo-4-methoxyphenyl acetic acid) 是一种海洋来源的天然产物,存在于 Ianthella quadrangulata。 | |||
TN1799 |
Isorubrofusarin-6-O-β-gentiobioside
Isorubrofusarin 10-gentiobioside |
BACE; AChR | Neuroscience |
Isorubrofusarin-6-O-β-gentiobioside 来源于 Cassia obtusifolia Linn 种子,对 AChE 和 BACE1 具有良好的抑制活性。 | |||
T7913 |
2-Bromobiphenyl
|
Others | Others |
2-Bromobiphenyl 是一种持久性有机污染物,主要存在于土壤和水中。它是一种已知的人类致癌物,与生殖和发育毒性等多种健康影响有关。 | |||
TN7205 |
Methyl 5,6-dibromo-1H-indole-3-carboxylate
5,6-Dibromo-1H-indole-3-carboxylic acid methyl ester |
Others | Others |
Methyl 5,6-dibromo-1H-indole-3-carboxylate (5,6-Dibromo-1H-indole-3-carboxylic acid methyl ester) 是一种海洋来源的天然产物,存在于Smenospongia sp.。 | |||
T10619 |
Bromelain
|
Apoptosis; Others | Apoptosis; Others |
Bromelain 是来源于菠萝茎的一种抗炎药,可诱导细胞凋亡,具有纤维蛋白溶解、抗癌、抗水肿和抗血栓形成活性。它通过下调血浆激肽原,抑制前列腺素 E2 表达,降解晚期糖基化终产物受体,在COX 途径上游发生抗氧化作用以及调节血管生成生物标志物而发挥作用。 | |||
TN7177 |
6-Bromoindole-3-carboxylic acid
6-溴吲哚-3-羧酸,ZINC2547985,6-Bromo-1H-indole-3-carboxylic acid |
Others | Others |
6-Bromoindole-3-carboxylic acid (ZINC2547985) 是一种海洋来源的天然产物,存在于Pseudosuberites hyalinus。 | |||
TN7164 |
2,7-Dibromo-9H-Carbazole
2,7-Dibromocarbazole,2,7-二溴咔唑 |
Others | Others |
2,7-Dibromo-9H-Carbazole (2,7-Dibromocarbazole) 是一种海洋来源的天然产物,存在于Kyrtuthrix maculans。 | |||
TN7221 |
6-Bromovanillin
|
||
6-Bromovanillin 是一种生化试剂,可用于用于合成caridopa。Caridopa 一种芳香氨基酸脱羧酶抑制剂。 | |||
T3524 |
Halofuginone hydrobromide
卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐 |
Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells |
Halofuginone hydrobromid 是Febrifugine 的衍生物,是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂,并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。 | |||
T0625 |
Theobromine
3, 7-Dimethylxanthine,可可碱,3,7-Dimethylxanthine |
Endogenous Metabolite; PDE; Adenosine Receptor | GPCR/G Protein; Metabolism; Neuroscience |
Theobromine (3,7-Dimethylxanthine) 是在可可豆中发现的一种甲基黄嘌呤,抑制腺苷受体 A1 信号传导,用作支气管扩张剂和血管扩张剂。 | |||
TN7146 |
2,6-Dibromo-4-(hydroxymethyl)phenol
ZINC2525484,2,6-二溴-4-(羟甲基)苯酚,3,5-dibromo-p-hydroxybenzyl alcohol,3,5-Dibromo-4-Hydroxybenzyl alcohol |
Others | Others |
2,6-Dibromo-4-(hydroxymethyl)phenol (3,5-dibromo-p-hydroxybenzyl alcohol) 是一种海洋来源的天然产物,存在于 Thelepus setosus。 | |||
TN7173 |
Methyl 5-bromo-1H-indole-3-carboxylate
5-溴吲哚-3-羧酸甲酯,Methyl 5-bromo-1H-indole-3-carboxylate |
Others | Others |
5-Bromo-1H-Indole-3-Carboxylic Acid Methyl Ester (Methyl 5-bromo-1H-indole-3-carboxylate) 是一种海洋来源的天然产物,存在于Smenospongia sp.。 | |||
TN7190 |
3-Bromo-4-Methoxyphenylacetonitrile
3-Bromo-4-methoxybenzyl Cyanide,ZINC2565991,2-(3-bromo-4-methoxyphenyl)acetonitrile,3-溴-4-甲氧基苯乙腈 |
Others | Others |
3-Bromo-4-Methoxyphenylacetonitrile (ZINC2565991) 是一种海洋来源的天然产物,存在于 Aiolochroia crassa。 | |||
T8060 |
5-Bromouracil
|
Others | Others |
5-Bromouracil 通过诱导 A 型样 DNA 破坏核小体定位。 | |||
TN7189 |
4,6-Dibromoindole
ZINC13450450,4,6-dibromo-1H-indole,4,6-二溴吲哚 |
Others | Others |
4,6-Dibromoindole (ZINC13450450) 是一种海洋来源的天然产物,存在于Glossobalanus sp.。 | |||
TN7140 |
1H-Pyrrole-2-carboxylic acid, 4,5-dibromo-1-methyl-
4,5-dibromo-1-methyl-1H-pyrrole-2-carboxylic acid,Methyl-4,5-dibromocarboxylic acid,1-methyl-4,5-dibromopyrrole-2-carboxylic acid,4,5-dibromo-1-methylpyrrole-2-carboxylic acid |
Others | Others |
1H-Pyrrole-2-carboxylic acid, 4,5-dibromo-1-methyl- (1-methyl-4,5-dibromopyrrole-2-carboxylic acid)是一种海洋来源的天然产物,存在于Agelas flabelliformis。 | |||
TN7198 |
6-Bromoindole-3-acetonitrile
6-溴吲哚-3-乙腈,6-Bromo-1H-indole-3-acetonitrile,ZINC13379652,2-(6-bromo-1H-indol-3-yl)acetonitrile |
Others | Others |
6-Bromoindole-3-acetonitrile (2-(6-bromo-1H-indol-3-yl)acetonitrile) 是一种海洋来源的天然产物,存在于Pseudosuberites hyalinus。 | |||
TN7163 |
Methyl 4-bromopyrrole-2-carboxylate
4-Bromo-2-(methoxycarbonyl)-1H-pyrrole,methyl 4-bromo-1H-pyrrole-2-carboxylate,4-溴-1H-吡咯-2-羧酸甲酯 |
Others | Others |
Methyl 4-bromopyrrole-2-carboxylate (4-Bromo-2-(methoxycarbonyl)-1H-pyrrole) 是一种海洋来源的天然产物,存在于 Lissodendoryx sp.。 | |||
TN7249 |
Nor-rubrofusarin gentiobioside
|
||
Nor-rubrofusarin gentiobioside 是从豆科植物决明子中发现的天然产物。 | |||
TN7192 |
7-Bromoquinazoline-2,4(1H,3H)-Dione
7-Bromo-2,4(1H,3H)-quinazolinedione,7-溴喹唑啉-(2,4)二酮,7-Bromo-1H-quinazoline-2,4-dione,7-bromoquinazoline-2,4-diol |
Others | Others |
7-Bromoquinazoline-2,4(1H,3H)-Dione (7-Bromo-2,4(1H,3H)-quinazolinedione) 是一种海洋来源的天然产物,发现于 Pyura sacciformis。 | |||
T19808 |
5-Bromo-5-nitro-1,3-dioxane
Bronidox,5-溴-5-硝基-1,3-二噁烷,5-溴-5-硝基-1,3-二恶烷 |
Others; Antibacterial; Antifungal | Microbiology/Virology; Others |
5-Bromo-5-nitro-1,3-dioxane (Bronidox) 是一种抗菌化合物,可通过必需蛋白硫醇的氧化抑制酶活性并随后抑制微生物的生长。它有抗革兰氏阳性和革兰氏阴性细菌,以及抗真菌活性。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00803 |
Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
GFND,LETS,ED-B,fibronectin 1,CIG,GFND2,FNZ,FINC,FN,... |
Human | HEK293 Cells |
Fibronectin Protein, Human, Recombinant (aa 607-1265, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.2 kDa and the accession number is P02751-15. | |||
TMPY-04801 |
Fibromodulin Protein, Human, Recombinant (hFc)
FM,fibromodulin,SLRR2E |
Human | HEK293 Cells |
Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FMOD of cancer cells may promote tumor angiogenesis of SCLC by upregulating the expression of angiogenic factors that act in concert to facilitate the angiogenic phenotype of endothelial cells as a proangiogenic factor. Therefore, silencing FMOD may be a potentially clinical therap... | |||
TMPY-05099 |
GBA/glucocerebrosidase Protein, Human, Recombinant (His)
glucosidase, β, acid,GLUC,GCB,GBA1,glucosidase, beta, acid |
Human | HEK293 Cells |
Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramidase 1) and GBA2 (glucocerebrosidase 2) enzymes that mediate glucosylsphingosine production and metabolism are attractive therapeutic targets for treating mutant GBA-associated PD. | |||
TMPK-01391 |
Fibronectin Protein, Human, Recombinant (aa 1266-1356, His)
FN1,LETS,GFND,MSF,FNZ,CIG,ED-B,FN,SMDCF,GFND2,FINC |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 1266-1356, His) is expressed in HEK293 mammalian cells with C-His tag. The predicte... | |||
TMPJ-01433 |
Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated
Fibronectin,FN1 |
Human | E. coli |
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, an... | |||
TMPK-01390 |
Fibronectin Protein, Human, Recombinant (aa 32-602, His)
FNZ,ED-B,SMDCF,FN1,GFND,MSF,GFND2,LETS,FN,FINC,CIG |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 32-602, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted m... | |||
TMPH-00204 |
Azurin Protein, Bordetella bronchiseptica, Recombinant (His & Myc)
BB3856,Azurin |
Bordetella bronchiseptica | E. coli |
Azurin Protein, Bordetella bronchiseptica, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.8 kDa and the accession number is P0A321. | |||
TMPH-01338 |
Fibronectin Protein, Human, Recombinant (His)
Fibronectin,Cold-insoluble globulin,FN1 |
Human | E. coli |
Fibronectin Protein, Human, Recombinant (His) is expressed in E. coli expression system with His-tag tag. The predicted molecular weight is 23.6 kDa and the accession number is P02751. | |||
TMPY-04929 |
Influenza A H5N8 (A/broiler duck/Korea/Buan2/2014) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N8 | Baculovirus Insect Cells |
Influenza A H5N8 (A/broiler duck/Korea/Buan2/2014) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60 kDa and the accession number is W8NQ99. | |||
TMPK-01373 |
Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc)
FINC,LETS,GFND,SMDCF,GFND2,ED-B,MSF,FNZ,FN1,FN,CIG |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicte... | |||
TMPK-01389 |
Fibronectin Protein, Human, Recombinant (aa 32-345, His)
MSF,ED-B,LETS,SMDCF,FN,GFND2,CIG,FNZ,FN1,GFND,FINC |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 32-345, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted m... | |||
TMPH-00048 |
Pectate lyase 1 Protein, Ambrosia artemisiifolia, Recombinant (His)
Protein AaBA,Pectate lyase 1,Antigen E,Pollen allergen Amb a... |
Ambrosia artemisiifolia | E. coli |
Has pectate lyase activity. | |||
TMPY-05562 |
Fibronectin Protein, Human, Recombinant (aa 1722-1811, His)
fibronectin 1,ED-B,CIG,FNZ,MSF,FN,FINC,GFND,LETS,GF... |
Human | HEK293 Cells |
Fibronectin Protein, Human, Recombinant (aa 1722-1811, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.3 kDa and the accession number is P02751-15. | |||
TMPH-00205 |
Azurin Protein, Bordetella bronchiseptica, Recombinant (His)
BB3856,Azurin |
Bordetella bronchiseptica | P. pastoris (Yeast) |
Azurin Protein, Bordetella bronchiseptica, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 15.8 kDa and the accession number is P0A321. | |||
TMPH-01756 |
Neurofibromin/NF1 Protein, Human, Recombinant (His & Myc)
Neurofibromin,Neurofibromatosis-related pr... |
Human | E. coli |
Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity. Neurofibromin/NF1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.7 kDa and the accession number is P21359. | |||
TMPY-04518 |
Influenza A H5N8 (A/broiler duck/Korea/Buan2/2014) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N8 | HEK293 Cells |
Influenza A H5N8 (A/broiler duck/Korea/Buan2/2014) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.2 kDa and the accession number is W8NQ99. | |||
TMPH-00049 |
Pectate lyase 5 Protein, Ambrosia artemisiifolia, Recombinant (His)
Pollen allergen Amb a 1.1,Pectate lyase 5,Antigen E,Antigen ... |
Ambrosia artemisiifolia | P. pastoris (Yeast) |
Has pectate lyase activity. | |||
TMPH-00050 |
Pectate lyase 5 Protein, Ambrosia artemisiifolia, Recombinant (His & SUMO)
Pectate lyase 5,Antigen Amb a I,Pollen allergen Amb a 1.1,An... |
Ambrosia artemisiifolia | E. coli |
Has pectate lyase activity. Pectate lyase 5 Protein, Ambrosia artemisiifolia, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.8 kDa and the accession number is P27759. |
Cat. No. | Product Name | Target | Signaling Pathways |
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T71143 |
Ambroxol-d5
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Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part... | |||
TMIH-0055 |
4-Bromochlorobenzene-d4
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4-Bromochlorobenzene-d4 是 4-Bromochlorobenzene 的氘代化合物。 | |||
T11273 |
Fenpiverinium D3 bromide
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Others | Others |
Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects.Fenpiverinium D3 bromide is a deuterium labeled Fenpiverinium bromide. | |||
TMIH-0054 |
4-Bromobenzoic acid-d4
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4-Bromobenzoic acid-d4 是 4-Bromobenzoic acid 的氘代化合物。4-Bromobenzoic acid 的 CAS 号为 586-76-5。 | |||
TMIJ-0014 |
Fenoterol-d6 Hydrobromide
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Fenoterol-d6 Hydrobromide 是 Fenoterol Hydrobromide 的氘代化合物。Fenoterol Hydrobromide 的 CAS 号为 1944-12-3。Fenoterol hydrobromide 是一种拟交感神经剂,是一种选择性的,具有口服活性 β2-肾上腺素受体 (β2-adrenoceptor) 激动剂,是一种有效的支气管扩张剂,可用于一种与哮喘、支气管炎和其他阻塞性气道疾病相关的支气管痉挛。 | |||
TMIJ-0234 |
Tiotropium Bromide EP Impurity G-d3 (Iodide)
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Tiotropium Bromide EP Impurity G-d3 (Iodide) 是 Tiotropium Bromide EP Impurity G (Iodide) 的氘代化合物。 | |||
TMIJ-0233 |
Tiotropium Bromide EP Impurity G-d3
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Tiotropium Bromide EP Impurity G-d3 是 Tiotropium Bromide EP Impurity G 的氘代化合物。Tiotropium Bromide EP Impurity G 的 CAS 号为 1508-46-9。 | |||
TMIJ-0270 |
Pinaverium-d4 Bromide (Mixture of Diastereomers)
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Pinaverium-d4 Bromide (Mixture of Diastereomers) 是 Pinaverium Bromide 的氘代化合物。Pinaverium Bromide 的 CAS 号为 53251-94-8。Pinaverium bromide 是一种具有解痉作用的钙通道阻滞剂,可有效缓解疼痛、腹泻和肠道不适。 | |||
TMIJ-0504 |
Neostigmine Bromide EP Impurity C-d6
Nor Neostigmine-d6 |
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Neostigmine Bromide EP Impurity C-d6 是 Neostigmine Bromide EP Impurity C 的氘代化合物。Neostigmine Bromide EP Impurity C 的 CAS 号为 16088-19-0。 | |||
T12018 |
Methylnaltrexone-d3 bromide
溴化甲基纳曲酮 D3,Methylnaltrexone D3 Bromide |
Others | Others |
Methylnaltrexone D3 Bromide is the deuterium labeled Methylnaltrexone Bromide. | |||
TMIH-0283 |
Ipratropium-d3 Bromide
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Ipratropium-d3 Bromide 是 Ipratropium Bromide 的氘代化合物。Ipratropium Bromide 的 CAS 号为 22254-24-6。Ipratropium bromide 是毒蕈碱的受体的拮抗剂,可用于 COPD 和哮喘等研究,对 M1、M2 和 M3 受体的结合的IC50值分别为 2.9、2 和 1.7 nM。 | |||
TMIH-0163 |
Clidinium Bromide-d5
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Clidinium Bromide-d5 是 Clidinium Bromide 的氘代化合物。Clidinium Bromide 的 CAS 号为 3485-62-9。Clidinium bromide 是季胺抗毒蕈碱剂,可通过减少胃酸和减慢肠道速度,缓解痉挛和腹部疼痛的症状。 | |||
TMIH-0027 |
1-Bromo-4-nitrobenzene-d4
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1-Bromo-4-nitrobenzene-d4 是 1-Bromo-4-nitrobenzene 的氘代化合物。 | |||
TMIJ-0104 |
Dibromoethane-d4
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Dibromoethane-d4 是 Dibromoethane 的氘代化合物。Dibromoethane 的 CAS 号为 106-93-4。 | |||
T12587 |
Pyridostigmine-d6 bromide
Pyridostigmine D6 bromide,溴化吡啶斯的明 D6 |
Others | Others |
Pyridostigmine D6 bromide is the deuterium labeled Pyridostigmine, which is a parasympathomimetic and a reversible inhibitor of cholinesterase. | |||
TMID-0030 |
4-Bromophenoxybenzene-d5
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4-Bromophenoxybenzene-d5 是 4-Bromophenoxybenzene 的氘代化合物。4-Bromophenoxybenzene 的 CAS 号为 101-55-3。 | |||
TMID-0232 |
Choline-d13 Bromide (N,N,N-trimethyl-d9; 1,1,2,2-d4)
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Choline-d13 Bromide (N,N,N-trimethyl-d9; 1,1,2,2-d4) 是 Choline Bromide 的氘代化合物。Choline Bromide 的 CAS 号为 1927-06-6。 | |||
TMIH-0125 |
Brombuterol-d9
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Brombuterol-d9 是 Brombuterol 的氘代化合物。 | |||
TMIJ-0186 |
Bromocriptine-13C-d3
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Bromocriptine-13C-d3 是 Bromocriptine 的 13C 和氘代化合物。Bromocriptine 的 CAS 号为 25614-03-3。 | |||
TMID-0089 |
Tetrabromobisphenol A-d4
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Tetrabromobisphenol A-d4 是 Tetrabromobisphenol A 的氘代化合物。Tetrabromobisphenol A 的 CAS 号为 79-94-7。 | |||
TMID-0095 |
2,4-DIBROMOPHENOL-3,5,6-d3
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2,4-DIBROMOPHENOL-3,5,6-d3 是 2,4-DIBROMOPHENOL 的氘代化合物。2,4-DIBROMOPHENOL 的 CAS 号为 615-58-7。 | |||
T71306 |
Gemfibrozil-d6
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Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif l... | |||
T71328 |
Theobromine-d6
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Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist. Theobromine increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium.... | |||
TMIH-0110 |
Benzbromarone-d5
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Benzbromarone-d5 是 Benzbromarone 的氘代化合物。Benzbromarone 的 CAS 号为 3562-84-3。Benzbromarone 是一种高效的,耐受性良好的非竞争性黄嘌呤氧化酶抑制剂,用作排尿酸剂,研究痛风。 | |||
TMIJ-0339 |
Bromhexine-d3 HCl
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Bromhexine-d3 HCl 是 Bromhexine HCl 的氘代化合物。Bromhexine HCl 的 CAS 号为 611-75-6。Bromhexine hydrochloride 是TMPRSS2蛋白酶的一种特异性有效抑制剂,IC50为 0.75 μM。它可预防和控制SARS-CoV-2感染。它是一种粘液溶解剂,用于治疗与粘稠或过多粘液相关的呼吸系统疾病。 |